{"id":"https://openalex.org/W2297822100","doi":null,"title":"Economic evaluation of dabigatran etexilate in the management of atrial fibrillation in Greece.","display_name":"Economic evaluation of dabigatran etexilate in the management of atrial fibrillation in Greece.","publication_year":2013,"publication_date":"2013-07-01","ids":{"openalex":"https://openalex.org/W2297822100","mag":"2297822100","pmid":"https://pubmed.ncbi.nlm.nih.gov/23912921"},"language":"en","primary_location":{"id":"pmid:23912921","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23912921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5129547326","display_name":"George K Andrikopoulos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094245","display_name":"National School of Public Health","ror":"https://ror.org/00mjaaf25","country_code":"GR","type":"education","lineage":["https://openalex.org/I4210094245"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"George K Andrikopoulos","raw_affiliation_strings":["National School of Public Health, Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National School of Public Health, Athens, Greece","institution_ids":["https://openalex.org/I4210094245"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108462376","display_name":"Vasilis Fragoulakis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vasilis Fragoulakis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Nikos Maniadakis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nikos Maniadakis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0896,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.78901663,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"54","issue":"4","first_page":"289","last_page":"300"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dabigatran-etexilate","display_name":"dabigatran etexilate","score":0.996999979019165},{"id":"https://openalex.org/keywords/non-valvular-atrial-fibrillation","display_name":"non-valvular atrial fibrillation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.8410000205039978},{"id":"https://openalex.org/keywords/cardioembolic-risk","display_name":"cardioembolic risk","score":0.6819999814033508},{"id":"https://openalex.org/keywords/stroke-prevention","display_name":"stroke prevention","score":0.7960000038146973},{"id":"https://openalex.org/keywords/warfarin","display_name":"warfarin","score":0.7239999771118164},{"id":"https://openalex.org/keywords/acenocoumarol","display_name":"acenocoumarol","score":0.9190000295639038},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.996999979019165},{"id":"https://openalex.org/keywords/markov-model","display_name":"Markov model","score":0.8399999737739563},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.9020000100135803},{"id":"https://openalex.org/keywords/social-security-burden","display_name":"social security burden","score":0.6510000228881836},{"id":"https://openalex.org/keywords/greece","display_name":"Greece","score":0.847000002861023}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9588278532028198},{"id":"https://openalex.org/C2778810321","wikidata":"https://www.wikidata.org/wiki/Q419345","display_name":"Dabigatran","level":4,"score":0.9546908140182495},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.6935181617736816},{"id":"https://openalex.org/C2776301958","wikidata":"https://www.wikidata.org/wiki/Q407431","display_name":"Warfarin","level":3,"score":0.6702232360839844},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4690476059913635},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.45566147565841675},{"id":"https://openalex.org/C2781344064","wikidata":"https://www.wikidata.org/wiki/Q304088","display_name":"Acenocoumarol","level":4,"score":0.4376711845397949},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3246854543685913},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.07009392976760864}],"mesh":[{"descriptor_ui":"D000069604","descriptor_name":"Dabigatran","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D001562","descriptor_name":"Benzimidazoles","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D001562","descriptor_name":"Benzimidazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003362","descriptor_name":"Cost-Benefit Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006115","descriptor_name":"Greece","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D017850","descriptor_name":"Economics, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019057","descriptor_name":"Quality-Adjusted Life Years","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D058833","descriptor_name":"Antithrombin Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:23912921","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23912921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese","raw_type":"Comparative Study"},{"id":"mag:2297822100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23912921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W86438867","https://openalex.org/W1882292014","https://openalex.org/W1969247937","https://openalex.org/W1971505725","https://openalex.org/W1973223229","https://openalex.org/W1973633212","https://openalex.org/W1979180382","https://openalex.org/W1992076253","https://openalex.org/W1993614294","https://openalex.org/W2022239683","https://openalex.org/W2024932164","https://openalex.org/W2042099226","https://openalex.org/W2047926237","https://openalex.org/W2055250748","https://openalex.org/W2056473894","https://openalex.org/W2060315753","https://openalex.org/W2074334843","https://openalex.org/W2078414845","https://openalex.org/W2082600085","https://openalex.org/W2083828641","https://openalex.org/W2085270509","https://openalex.org/W2089367188","https://openalex.org/W2089534375","https://openalex.org/W2095783086","https://openalex.org/W2096719451","https://openalex.org/W2097156473","https://openalex.org/W2107326822","https://openalex.org/W2109943085","https://openalex.org/W2111466538","https://openalex.org/W2117807679","https://openalex.org/W2119808478","https://openalex.org/W2125757462","https://openalex.org/W2132505348","https://openalex.org/W2136489990","https://openalex.org/W2137434301","https://openalex.org/W2145737292","https://openalex.org/W2148056560","https://openalex.org/W2164238702","https://openalex.org/W2164861810","https://openalex.org/W2171088836","https://openalex.org/W2183459510","https://openalex.org/W2187805540","https://openalex.org/W2413185619","https://openalex.org/W2463589070"],"related_works":["https://openalex.org/W2096719451","https://openalex.org/W2045499352","https://openalex.org/W2022149251","https://openalex.org/W2931762292","https://openalex.org/W1979708394","https://openalex.org/W2030619174","https://openalex.org/W2292929634","https://openalex.org/W2083828641","https://openalex.org/W2122348080","https://openalex.org/W2541580365"],"abstract_inverted_index":{"INTRODUCTION:":[0],"The":[1,65,87,106,142],"objective":[2],"of":[3,27,54,60,83,92,114,132,147,169,182,195,204],"the":[4,25,46,51,55,58,73,76,81,90,93,98,122,154,166,179,193],"present":[5],"study":[6],"was":[7,43,158,172],"to":[8,18,45,49,121,128,140,152,162],"evaluate,":[9],"from":[10,35,97,126,138],"an":[11],"economic":[12,70,103],"perspective,":[13],"dabigatran":[14,115,133,148],"etexilate":[15,186],"in":[16,198],"comparison":[17],"existing":[19,40],"pharmaceutical":[20],"therapeutic":[21],"options":[22],"available":[23],"for":[24,75,89,192],"protection":[26],"moderate-to-high":[28,202],"risk":[29,203],"patients":[30,61,200],"with":[31,62],"non-valvular":[32],"atrial":[33],"fibrillation":[34],"cardioembolic":[36],"risk.":[37],"METHODS:":[38],"An":[39],"Markov":[41],"model":[42,66,94],"adapted":[44],"Greek":[47],"setting":[48],"reflect":[50],"natural":[52],"course":[53,82],"disease":[56],"and":[57,69,72,101,130,160,164,174],"management":[59],"different":[63],"therapies.":[64],"predicts":[67],"health":[68],"outcomes":[71],"implications":[74],"social":[77],"security":[78],"system":[79],"during":[80],"a":[84,189],"patient's":[85],"lifetime.":[86],"data":[88],"population":[91],"were":[95],"derived":[96],"international":[99],"literature":[100],"local":[102,167,180],"databases.":[104],"RESULTS:":[105],"incremental":[107,143],"cost":[108,144],"per":[109,145],"quality-adjusted":[110],"life":[111],"year":[112],"(QALY)":[113],"150":[116,149],"mg":[117,135,150],"twice":[118,136],"daily":[119,137],"relative":[120,151,161],"other":[123],"therapies":[124],"varied":[125],"\u20ac5547":[127],"\u20ac11,762":[129,159],"that":[131],"110":[134],"\u20ac7398":[139],"\u20ac16,437.":[141],"QALY":[146],"aspirin,":[153],"least":[155],"costly":[156],"option,":[157],"warfarin":[163],"acenocoumarol,":[165],"standards":[168],"care,":[170],"it":[171],"\u20ac11,400":[173],"\u20ac11,224":[175],"respectively,":[176],"well":[177],"below":[178],"thresholds":[181],"acceptance.":[183],"CONCLUSION:":[184],"Dabigatran":[185],"may":[187],"represent":[188],"cost-effective":[190],"option":[191],"prevention":[194],"thromboembolic":[196],"events":[197],"AF":[199],"at":[201],"stroke":[205],"or":[206],"systemic":[207],"embolism.":[208]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}