{"id":"https://openalex.org/W2296777588","doi":null,"title":"The influence of vascular risk factors and white matter hyperintensities on the degree of cognitive impairment in Parkinson's disease.","display_name":"The influence of vascular risk factors and white matter hyperintensities on the degree of cognitive impairment in Parkinson's disease.","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W2296777588","mag":"2296777588","pmid":"https://pubmed.ncbi.nlm.nih.gov/16967348"},"language":"pl","primary_location":{"id":"pmid:16967348","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16967348","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia i neurochirurgia polska","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5139289292","display_name":"Jaros\u0142aw S\u0142awek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75124487","display_name":"Gda\u0144sk Medical University","ror":"https://ror.org/019sbgd69","country_code":"PL","type":"education","lineage":["https://openalex.org/I75124487"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Jaros\u0142aw S\u0142awek","raw_affiliation_strings":["Zak\u0142ad Piel\u00eagniarstwa Neurologiczno-Psychiatrycznego, Akademia Medyczna w Gda\u0144sku, Szpital Specjalistyczny oew. Wojciecha, Al. Jana Paw\u0142a II 50, 80-462 Gda\u0144sk. jaroslawek@amg.gda.pl"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zak\u0142ad Piel\u00eagniarstwa Neurologiczno-Psychiatrycznego, Akademia Medyczna w Gda\u0144sku, Szpital Specjalistyczny oew. Wojciecha, Al. Jana Paw\u0142a II 50, 80-462 Gda\u0144sk. jaroslawek@amg.gda.pl","institution_ids":["https://openalex.org/I75124487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011399242","display_name":"Dariusz Wieczorek","orcid":"https://orcid.org/0000-0003-4446-8927","observed_orcids":["https://orcid.org/0000-0003-4446-8927"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dariusz Wieczorek","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111667977","display_name":"Miros\u0142awa Derejko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153937","display_name":"Institute of Psychiatry and Neurology","ror":"https://ror.org/0468k6j36","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210153937"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Miros\u0142awa Derejko","raw_affiliation_strings":["Zak\u0142ad Neurofizjologii Klinicznej, Instytut Psychiatrii i Neurologii, ul. Sobieskiego 9, 02-957 Warszawa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zak\u0142ad Neurofizjologii Klinicznej, Instytut Psychiatrii i Neurologii, ul. Sobieskiego 9, 02-957 Warszawa","institution_ids":["https://openalex.org/I4210153937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113668815","display_name":"Miros\u0142awa Dubaniewicz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miros\u0142awa Dubaniewicz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065674486","display_name":"Bogna Brockhuis","orcid":"https://orcid.org/0000-0002-9035-6160","observed_orcids":["https://orcid.org/0000-0002-9035-6160"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bogna Brockhuis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090159415","display_name":"Emilia Jadwiga Sitek","orcid":"https://orcid.org/0000-0003-4141-072X","observed_orcids":["https://orcid.org/0000-0003-4141-072X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emilia Sitek","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081876877","display_name":"Lucyna Wilczewska","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucyna Wilczewska","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079663499","display_name":"Anna Roszmann","orcid":"https://orcid.org/0000-0003-3865-3667","observed_orcids":["https://orcid.org/0000-0003-3865-3667"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Roszmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5062389804","display_name":"Piotr Lass","orcid":"https://orcid.org/0000-0001-7144-1370","observed_orcids":["https://orcid.org/0000-0001-7144-1370"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piotr Lass","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1064,"has_fulltext":false,"cited_by_count":53,"citation_normalized_percentile":{"value":0.78906535,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"40","issue":"4","first_page":"276","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9526000022888184,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.03200000151991844,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/vascular-risk-factors","display_name":"vascular risk factors","score":0.9049999713897705},{"id":"https://openalex.org/keywords/white-matter-hyperintensities","display_name":"white matter hyperintensities","score":1.0},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.8820000290870667},{"id":"https://openalex.org/keywords/motor-impairment","display_name":"motor impairment","score":0.8769999742507935},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7400000095367432},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.800000011920929},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.890999972820282},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.7590000033378601},{"id":"https://openalex.org/keywords/alcohol-abuse","display_name":"alcohol abuse","score":0.9629999995231628},{"id":"https://openalex.org/keywords/unified-parkinson-s-disease-rating-scale","display_name":"Unified Parkinson's Disease Rating Scale","score":0.7929999828338623},{"id":"https://openalex.org/keywords/hoehn-and-yahr-stage","display_name":"Hoehn and Yahr stage","score":0.8640000224113464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8335092067718506},{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.7265613079071045},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6119401454925537},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.49950480461120605},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.4869476556777954},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.4827665388584137},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4786714017391205},{"id":"https://openalex.org/C2776191500","wikidata":"https://www.wikidata.org/wiki/Q2123166","display_name":"Leukoaraiosis","level":4,"score":0.45206013321876526},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.4440827965736389},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4187612235546112},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.391031414270401},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.24063342809677124},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.19757142663002014},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.08064380288124084},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009460","descriptor_name":"Neurologic Examination","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011597","descriptor_name":"Psychomotor Performance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D019957","descriptor_name":"Motor Skills Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D019957","descriptor_name":"Motor Skills Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:16967348","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16967348","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia i neurochirurgia polska","raw_type":"English Abstract"},{"id":"pmid:19235103","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19235103","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurologia i neurochirurgia polska","raw_type":"Journal Article"},{"id":"mag:2296777588","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16967348","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4292635960","https://openalex.org/W2460848525","https://openalex.org/W3081535812","https://openalex.org/W2889045374","https://openalex.org/W2109490889","https://openalex.org/W1987631753","https://openalex.org/W2794239424","https://openalex.org/W2896306174","https://openalex.org/W4200539887","https://openalex.org/W3010333991"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,39],"PURPOSE:":[2],"The":[3,235],"aim":[4],"of":[5,13,57,74,96,110,136,157,183,217,237,246,264,274,278,289],"the":[6,11,72,94,108,155,181,214,222,249,262,265,272,287],"study":[7],"was":[8,77,132,143],"to":[9,65,92,167],"assess":[10,93],"prevalence":[12,109],"vascular":[14,112,140,162,189,218,279],"risk":[15,113,141,163,190,219,280],"factors":[16,114,164,176,191,212,220,281],"and":[17,28,47,85,122,130,160,171,192,213,229,276],"white":[18],"matter":[19],"hyperintensities":[20],"(WMH)":[21],"in":[22,79,145,201,208,248,256,292],"patients":[23,42,81,89,147,158,184,203,238],"with":[24,43,62,159,165,185,224,239,244,286],"Parkinson's":[25],"disease":[26,58],"(PD)":[27],"its":[29],"impact":[30],"on":[31],"clinical":[32,169,211,259],"features":[33],"such":[34],"as":[35],"motor":[36,75,290],"impairment.":[37],"MATERIAL":[38],"METHODS:":[40],"60":[41],"PD":[44],"[25":[45],"women":[46],"35":[48],"men;":[49],"mean":[50,55],"age":[51],"68.4":[52],"(51-81)":[53],"years,":[54],"duration":[56],"8.4":[59],"(1-27)":[60],"years]":[61],"good":[63],"response":[64],"L-Dopa":[66],"were":[67,152,233],"studied.":[68],"Besides":[69],"neurological":[70],"examination,":[71],"degree":[73,95,288],"impairment":[76],"evaluated":[78],"all":[80,168,209,257],"using":[82,98],"UPDRS,":[83],"Hoehn-Yahr,":[84],"Schwab-England":[86],"scales.":[87],"All":[88],"underwent":[90],"MRI":[91],"WMH":[97,195,232,275],"Age":[99],"Related":[100],"White":[101],"Matter":[102],"Changes":[103],"(ARWMC)":[104],"Wahlund":[105,250],"scale.":[106],"Moreover,":[107],"classic":[111],"included":[115],"arterial":[116],"hypertension,":[117],"diabetes":[118],"mellitus":[119],"t.":[120],"1":[121],"2;":[123],"plasma":[124],"cholesterol,":[125],"cardiovascular":[126],"diseases,":[127],"alcohol":[128],"abuse":[129],"smoking":[131],"assessed.":[133],"RESULTS:":[134],"Presence":[135],"at":[137,240],"least":[138,241],"one":[139,242],"factor":[142],"noted":[144],"19":[146],"(31.7%).":[148],"No":[149,205],"significant":[150,206],"differences":[151,207],"found":[153],"between":[154,180,221],"groups":[156,182,223],"without":[161,230],"regard":[166],"parameters":[170,260],"total":[172,215],"ARWMC":[173],"score.":[174],"These":[175],"did":[177,252],"not":[178,253,283],"differ":[179,254],"more":[186],"than":[187],"3":[188],"other":[193],"patients.":[194,266],"(ARWMC":[196,225],">":[197,226],"or":[198,227],"=1)":[199,228],"occurred":[200],"33":[202],"(55%).":[204],"analysed":[210,258],"number":[216],"(ARWMC=0)":[231],"found.":[234],"group":[236],"focus":[243],"score":[245],"2":[247],"scale":[251],"significantly":[255,284],"from":[261],"rest":[263],"CONCLUSIONS:":[267],"Our":[268],"data":[269],"suggest":[270],"that":[271],"severity":[273],"incidence":[277],"are":[282],"related":[285],"disability":[291],"PD.":[293]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}