{"id":"https://openalex.org/W2294040586","doi":"https://doi.org/10.2147/ndt.s100597","title":"Brain oscillations in bipolar disorder and lithium-induced changes","display_name":"Brain oscillations in bipolar disorder and lithium-induced changes","publication_year":2016,"publication_date":"2016-03-01","ids":{"openalex":"https://openalex.org/W2294040586","doi":"https://doi.org/10.2147/ndt.s100597","mag":"2294040586","pmid":"https://pubmed.ncbi.nlm.nih.gov/27022264","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4788370"},"language":"en","primary_location":{"id":"doi:10.2147/ndt.s100597","doi":"https://doi.org/10.2147/ndt.s100597","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ndt.s100597","pdf_url":"https://www.dovepress.com/getfile.php?fileID=29290","source":{"id":"https://openalex.org/S124245730","display_name":"Neuropsychiatric Disease and Treatment","issn_l":"1176-6328","issn":["1176-6328","1178-2021"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric Disease and Treatment","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=29290","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071991377","display_name":"Murat \u0130lhan Atag\u00fcn","orcid":"https://orcid.org/0000-0002-8514-0576","observed_orcids":["https://orcid.org/0000-0002-8514-0576"]},"institutions":[{"id":"https://openalex.org/I4210150808","display_name":"Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University","ror":"https://ror.org/05ryemn72","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210150808"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Murat \u0130lhan Atag\u00fcn","raw_affiliation_strings":["Department of Psychiatry, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Medical School, Cankaya, Ankara, Turkey","Department of Psychiatry, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Medical School, Eski\u015fehir Highway No 6, Cankaya 6400, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Medical School, Cankaya, Ankara, Turkey","institution_ids":["https://openalex.org/I4210150808"]},{"raw_affiliation_string":"Department of Psychiatry, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University Medical School, Eski\u015fehir Highway No 6, Cankaya 6400, Ankara, Turkey","institution_ids":["https://openalex.org/I4210150808"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5071991377"],"corresponding_institution_ids":["https://openalex.org/I4210150808"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.2388,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.24732069,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"12","issue":null,"first_page":"589","last_page":"589"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":0.9940000176429749},{"id":"https://openalex.org/keywords/lithium","display_name":"lithium","score":0.9480000138282776},{"id":"https://openalex.org/keywords/neural-oscillations","display_name":"neural oscillations","score":0.9649999737739563},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"EEG","score":0.7670000195503235},{"id":"https://openalex.org/keywords/delta-waves","display_name":"delta oscillations","score":0.8679999709129333},{"id":"https://openalex.org/keywords/theta-oscillations","display_name":"theta oscillations","score":1.0},{"id":"https://openalex.org/keywords/beta-oscillations","display_name":"beta oscillations","score":0.9959999918937683},{"id":"https://openalex.org/keywords/event-related-oscillations","display_name":"event-related oscillations","score":0.8600000143051147},{"id":"https://openalex.org/keywords/resting-state-eeg","display_name":"resting-state EEG","score":0.8849999904632568},{"id":"https://openalex.org/keywords/serum-lithium-levels","display_name":"serum lithium levels","score":0.9179999828338623},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7739999890327454}],"concepts":[{"id":"https://openalex.org/C2778541603","wikidata":"https://www.wikidata.org/wiki/Q152763","display_name":"Lithium (medication)","level":2,"score":0.8413858413696289},{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.7369436025619507},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.718343198299408},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6051695942878723},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5040296912193298},{"id":"https://openalex.org/C120843803","wikidata":"https://www.wikidata.org/wiki/Q4955807","display_name":"Brain activity and meditation","level":3,"score":0.4412878453731537},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2937602996826172},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.24319350719451904}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/ndt.s100597","doi":"https://doi.org/10.2147/ndt.s100597","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ndt.s100597","pdf_url":"https://www.dovepress.com/getfile.php?fileID=29290","source":{"id":"https://openalex.org/S124245730","display_name":"Neuropsychiatric Disease and Treatment","issn_l":"1176-6328","issn":["1176-6328","1178-2021"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric Disease and Treatment","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3774843","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4788370","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4788370","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4788370","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatr Dis Treat","raw_type":"Text"},{"id":"pmid:27022264","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27022264","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric disease and treatment","raw_type":"Journal Article"},{"id":"pmh:10e0ffa6-caf1-4951-8b1d-ae3a0a5405af","doi":null,"is_oa":false,"landing_page_url":"https://avesis.comu.edu.tr/publication/details/10e0ffa6-caf1-4951-8b1d-ae3a0a5405af/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055198","display_name":"\u00c7anakkale Onsekiz Mart University AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/ndt.s100597","doi":"https://doi.org/10.2147/ndt.s100597","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ndt.s100597","pdf_url":"https://www.dovepress.com/getfile.php?fileID=29290","source":{"id":"https://openalex.org/S124245730","display_name":"Neuropsychiatric Disease and Treatment","issn_l":"1176-6328","issn":["1176-6328","1178-2021"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric Disease and Treatment","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2294040586.pdf","grobid_xml":"https://content.openalex.org/works/W2294040586.grobid-xml"},"referenced_works_count":138,"referenced_works":["https://openalex.org/W172071297","https://openalex.org/W197406896","https://openalex.org/W332101534","https://openalex.org/W1481369757","https://openalex.org/W1514574906","https://openalex.org/W1542946990","https://openalex.org/W1570893431","https://openalex.org/W1735445987","https://openalex.org/W1773565653","https://openalex.org/W1857638364","https://openalex.org/W1892364789","https://openalex.org/W1965269109","https://openalex.org/W1965544466","https://openalex.org/W1966058655","https://openalex.org/W1966135001","https://openalex.org/W1966235096","https://openalex.org/W1966977193","https://openalex.org/W1967397654","https://openalex.org/W1968616230","https://openalex.org/W1970520385","https://openalex.org/W1971653817","https://openalex.org/W1973125755","https://openalex.org/W1975481880","https://openalex.org/W1976822415","https://openalex.org/W1982291930","https://openalex.org/W1984935769","https://openalex.org/W1986677428","https://openalex.org/W1989278867","https://openalex.org/W1989821296","https://openalex.org/W1990007003","https://openalex.org/W1991545546","https://openalex.org/W1992008891","https://openalex.org/W1996141026","https://openalex.org/W1998796165","https://openalex.org/W2001747740","https://openalex.org/W2003446006","https://openalex.org/W2003463648","https://openalex.org/W2008639041","https://openalex.org/W2010009395","https://openalex.org/W2014596688","https://openalex.org/W2016631595","https://openalex.org/W2021386843","https://openalex.org/W2026834521","https://openalex.org/W2027897479","https://openalex.org/W2028129568","https://openalex.org/W2030556473","https://openalex.org/W2032408124","https://openalex.org/W2032711010","https://openalex.org/W2033456614","https://openalex.org/W2035081484","https://openalex.org/W2036007897","https://openalex.org/W2036645215","https://openalex.org/W2039190189","https://openalex.org/W2039576727","https://openalex.org/W2042311142","https://openalex.org/W2043213104","https://openalex.org/W2045143577","https://openalex.org/W2045270720","https://openalex.org/W2046168093","https://openalex.org/W2047967295","https://openalex.org/W2049031623","https://openalex.org/W2050135235","https://openalex.org/W2051805052","https://openalex.org/W2052209587","https://openalex.org/W2052610419","https://openalex.org/W2054764490","https://openalex.org/W2055387879","https://openalex.org/W2058404051","https://openalex.org/W2058897365","https://openalex.org/W2061054583","https://openalex.org/W2063847663","https://openalex.org/W2064119873","https://openalex.org/W2068557183","https://openalex.org/W2069247119","https://openalex.org/W2070915654","https://openalex.org/W2072149409","https://openalex.org/W2072319692","https://openalex.org/W2076361433","https://openalex.org/W2077112901","https://openalex.org/W2078571588","https://openalex.org/W2079173805","https://openalex.org/W2079659716","https://openalex.org/W2081843146","https://openalex.org/W2082674503","https://openalex.org/W2082769948","https://openalex.org/W2083733140","https://openalex.org/W2086609236","https://openalex.org/W2088555893","https://openalex.org/W2088601627","https://openalex.org/W2088863821","https://openalex.org/W2091125653","https://openalex.org/W2091960711","https://openalex.org/W2092068573","https://openalex.org/W2094919766","https://openalex.org/W2094932569","https://openalex.org/W2098479924","https://openalex.org/W2099235397","https://openalex.org/W2100229639","https://openalex.org/W2102056454","https://openalex.org/W2103355154","https://openalex.org/W2114853774","https://openalex.org/W2117563432","https://openalex.org/W2120768649","https://openalex.org/W2121999864","https://openalex.org/W2122663873","https://openalex.org/W2125700525","https://openalex.org/W2126774165","https://openalex.org/W2127389037","https://openalex.org/W2129429355","https://openalex.org/W2132560561","https://openalex.org/W2135812219","https://openalex.org/W2137688180","https://openalex.org/W2138953643","https://openalex.org/W2142790764","https://openalex.org/W2144406744","https://openalex.org/W2145490238","https://openalex.org/W2145653173","https://openalex.org/W2146348136","https://openalex.org/W2147804098","https://openalex.org/W2148992219","https://openalex.org/W2151119669","https://openalex.org/W2154533983","https://openalex.org/W2157693613","https://openalex.org/W2160137276","https://openalex.org/W2165807458","https://openalex.org/W2165902008","https://openalex.org/W2168497148","https://openalex.org/W2267368124","https://openalex.org/W2329582511","https://openalex.org/W2402216094","https://openalex.org/W2404142708","https://openalex.org/W2417121581","https://openalex.org/W3154410958","https://openalex.org/W4241852872","https://openalex.org/W6608853120","https://openalex.org/W6632668414","https://openalex.org/W6945527279","https://openalex.org/W7073601655"],"related_works":["https://openalex.org/W1965269109","https://openalex.org/W2122663873","https://openalex.org/W172071297","https://openalex.org/W3011383282","https://openalex.org/W1998796165","https://openalex.org/W3154410958","https://openalex.org/W4285731319","https://openalex.org/W2102079928","https://openalex.org/W1989059754","https://openalex.org/W7199332802"],"abstract_inverted_index":{"Electroencephalography":[0],"(EEG)":[1],"studies":[2,64],"in":[3,12,26,42,54,60,95,103,118,133,141,150,168],"patients":[4],"with":[5],"bipolar":[6,27,43,142],"disorder":[7,28,44,143],"have":[8],"revealed":[9],"lower":[10],"amplitudes":[11],"brain":[13,52,88,96,108,119],"oscillations.":[14,81],"The":[15],"aim":[16],"of":[17,51,72,74,113,138],"this":[18],"review":[19],"is":[20,77,144],"to":[21,30,79,100,125,131,146,160],"describe":[22],"lithium-induced":[23,39,101,116,163],"EEG":[24,40,63,164],"changes":[25,41,94,117,165],"and":[29,58,87],"discuss":[31],"potential":[32],"underlying":[33],"factors.":[34],"A":[35],"literature":[36],"survey":[37],"about":[38],"was":[45],"performed.":[46],"Lithium":[47],"consistently":[48],"enhances":[49],"magnitudes":[50,73],"oscillations":[53,69,76,89,97,120],"slow":[55],"frequencies":[56],"(delta":[57],"theta)":[59],"both":[61],"resting-state":[62],"as":[65,67,166],"well":[66],"event-related":[68,80],"studies.":[70,170],"Enhancement":[71],"beta":[75],"specific":[78],"Correlation":[82],"between":[83],"serum":[84],"lithium":[85,139],"levels":[86],"has":[90],"been":[91],"reported.":[92],"Lithium-induced":[93],"might":[98],"correspond":[99],"alterations":[102],"neurotransmitters,":[104],"signaling":[105],"cascades,":[106],"plasticity,":[107],"structure,":[109],"or":[110],"biophysical":[111],"properties":[112],"lithium.":[114],"Therefore,":[115],"could":[121],"be":[122,157],"promising":[123,159],"biomarkers":[124,167],"assess":[126,161],"the":[127,136,147,151,162],"molecular":[128],"mechanisms":[129,152],"leading":[130],"variability":[132,137],"efficacy.":[134],"Since":[135],"response":[140],"due":[145],"genetic":[148,169],"differences":[149],"involving":[153],"lithium,":[154],"it":[155],"would":[156],"highly":[158]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}