{"id":"https://openalex.org/W2292185341","doi":null,"title":"IMPACTO DO METILFENIDATO SOBRE A FREQU\u00caNCIA E A GRAVIDADE DAS CRISES EPIL\u00c9PTICAS EM CRIAN\u00c7AS COM O TRANSTORNO DE D\u00c9FICIT DE ATEN\u00c7\u00c3O E HIPERATIVIDADE (TDAH) ASSOCIADO A EPILEPSIAS DE DIF\u00cdCIL CONTROLE.","display_name":"IMPACTO DO METILFENIDATO SOBRE A FREQU\u00caNCIA E A GRAVIDADE DAS CRISES EPIL\u00c9PTICAS EM CRIAN\u00c7AS COM O TRANSTORNO DE D\u00c9FICIT DE ATEN\u00c7\u00c3O E HIPERATIVIDADE (TDAH) ASSOCIADO A EPILEPSIAS DE DIF\u00cdCIL CONTROLE.","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2292185341","mag":"2292185341"},"language":"pt","primary_location":{"id":"pmh:oai:americanae.aecid.es:1592927","doi":null,"is_oa":true,"landing_page_url":"http://tede2.pucrs.br/tede2/handle/tede/1605","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Biblioteca Digital de Teses e Disserta\u00e7\u00f5es da PUC_RS","raw_type":"info:eu-repo/semantics/masterThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://tede2.pucrs.br/tede2/handle/tede/1605","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080243082","display_name":"Kleber Santos","orcid":"https://orcid.org/0009-0007-3979-8805","observed_orcids":["https://orcid.org/0009-0007-3979-8805"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kleber Santos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5080243082"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.61080002784729,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.61080002784729,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.38429999351501465,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methylphenidate","display_name":"methylphenidate","score":0.9850000143051147},{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9020000100135803},{"id":"https://openalex.org/keywords/epilepsy","display_name":"epilepsy","score":0.550000011920929},{"id":"https://openalex.org/keywords/seizure-frequency","display_name":"seizure frequency","score":0.7210000157356262},{"id":"https://openalex.org/keywords/seizure-severity","display_name":"seizure severity","score":0.9079999923706055},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.5950000286102295},{"id":"https://openalex.org/keywords/stimulant-medication","display_name":"stimulant medication","score":0.3799999952316284},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.8519999980926514},{"id":"https://openalex.org/keywords/antiepileptic-drugs","display_name":"antiepileptic drugs","score":0.8029999732971191},{"id":"https://openalex.org/keywords/adhd-symptom-severity","display_name":"ADHD symptom severity","score":0.43799999356269836},{"id":"https://openalex.org/keywords/hass","display_name":"Hass","score":0.41100001335144043},{"id":"https://openalex.org/keywords/snap-iv","display_name":"SNAP-IV","score":0.9319999814033508}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6292837262153625}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:americanae.aecid.es:1592927","doi":null,"is_oa":true,"landing_page_url":"http://tede2.pucrs.br/tede2/handle/tede/1605","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Biblioteca Digital de Teses e Disserta\u00e7\u00f5es da PUC_RS","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"pmh:oai:tede2.pucrs.br:tede/1605","doi":null,"is_oa":true,"landing_page_url":"http://tede2.pucrs.br/tede2/handle/tede/1605","pdf_url":"http://tede2.pucrs.br/tede2/handle/tede/1605","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:PUC_RS","raw_type":"info:eu-repo/semantics/masterThesis"},{"id":"mag:2292185341","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.pucrs.br/dspace/bitstream/10923/4446/1/000429858-Texto%2bCompleto-0.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:americanae.aecid.es:1592927","doi":null,"is_oa":true,"landing_page_url":"http://tede2.pucrs.br/tede2/handle/tede/1605","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Biblioteca Digital de Teses e Disserta\u00e7\u00f5es da PUC_RS","raw_type":"info:eu-repo/semantics/masterThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2292185341.pdf","grobid_xml":"https://content.openalex.org/works/W2292185341.grobid-xml"},"referenced_works_count":125,"referenced_works":["https://openalex.org/W54916108","https://openalex.org/W118481987","https://openalex.org/W174556475","https://openalex.org/W295779251","https://openalex.org/W611912750","https://openalex.org/W1462033058","https://openalex.org/W1488067636","https://openalex.org/W1496742187","https://openalex.org/W1501899422","https://openalex.org/W1507979910","https://openalex.org/W1920696238","https://openalex.org/W1964982339","https://openalex.org/W1974148982","https://openalex.org/W1974799637","https://openalex.org/W1974809694","https://openalex.org/W1975467330","https://openalex.org/W1975778456","https://openalex.org/W1976013747","https://openalex.org/W1980110135","https://openalex.org/W1983105085","https://openalex.org/W1983302342","https://openalex.org/W1984848531","https://openalex.org/W1985010422","https://openalex.org/W1985127286","https://openalex.org/W1987656230","https://openalex.org/W1989251972","https://openalex.org/W1989984708","https://openalex.org/W1990586871","https://openalex.org/W1992213237","https://openalex.org/W1993757011","https://openalex.org/W1994391757","https://openalex.org/W1994909483","https://openalex.org/W1997603755","https://openalex.org/W2002844950","https://openalex.org/W2002883969","https://openalex.org/W2007725902","https://openalex.org/W2008123860","https://openalex.org/W2008237562","https://openalex.org/W2009989242","https://openalex.org/W2010321588","https://openalex.org/W2011684756","https://openalex.org/W2020145782","https://openalex.org/W2022587073","https://openalex.org/W2023323019","https://openalex.org/W2025551837","https://openalex.org/W2026327516","https://openalex.org/W2029080909","https://openalex.org/W2030201962","https://openalex.org/W2030295789","https://openalex.org/W2031416368","https://openalex.org/W2034939353","https://openalex.org/W2045549224","https://openalex.org/W2047585807","https://openalex.org/W2047768075","https://openalex.org/W2050866724","https://openalex.org/W2053341045","https://openalex.org/W2055031312","https://openalex.org/W2056177447","https://openalex.org/W2056319469","https://openalex.org/W2062378815","https://openalex.org/W2066078840","https://openalex.org/W2066186798","https://openalex.org/W2066644618","https://openalex.org/W2067282805","https://openalex.org/W2068438517","https://openalex.org/W2071199156","https://openalex.org/W2072064155","https://openalex.org/W2077465062","https://openalex.org/W2078794894","https://openalex.org/W2079634644","https://openalex.org/W2079843316","https://openalex.org/W2080522717","https://openalex.org/W2080575278","https://openalex.org/W2082269306","https://openalex.org/W2085253253","https://openalex.org/W2085406411","https://openalex.org/W2085990068","https://openalex.org/W2086016890","https://openalex.org/W2086188333","https://openalex.org/W2087555464","https://openalex.org/W2088383746","https://openalex.org/W2092136524","https://openalex.org/W2093348847","https://openalex.org/W2096544279","https://openalex.org/W2096695182","https://openalex.org/W2101525666","https://openalex.org/W2103024352","https://openalex.org/W2103400599","https://openalex.org/W2104485289","https://openalex.org/W2106874245","https://openalex.org/W2108370857","https://openalex.org/W2108423649","https://openalex.org/W2109087679","https://openalex.org/W2111839182","https://openalex.org/W2120731293","https://openalex.org/W2121654575","https://openalex.org/W2125096778","https://openalex.org/W2126661869","https://openalex.org/W2127294790","https://openalex.org/W2127743977","https://openalex.org/W2128466473","https://openalex.org/W2137361770","https://openalex.org/W2138604344","https://openalex.org/W2141588159","https://openalex.org/W2144668641","https://openalex.org/W2146994054","https://openalex.org/W2150549340","https://openalex.org/W2152292563","https://openalex.org/W2154685800","https://openalex.org/W2155681178","https://openalex.org/W2156645869","https://openalex.org/W2164864696","https://openalex.org/W2169328132","https://openalex.org/W2170755336","https://openalex.org/W2171074660","https://openalex.org/W2244966181","https://openalex.org/W2314647810","https://openalex.org/W2413912182","https://openalex.org/W2416660046","https://openalex.org/W2419257021","https://openalex.org/W2601578636","https://openalex.org/W2992831435","https://openalex.org/W2993504029","https://openalex.org/W4247972233","https://openalex.org/W4320288074"],"related_works":["https://openalex.org/W7010422022","https://openalex.org/W7120498940","https://openalex.org/W7120843803","https://openalex.org/W7006473160","https://openalex.org/W2104394920","https://openalex.org/W2903417403","https://openalex.org/W1844592306","https://openalex.org/W4390266646","https://openalex.org/W2280461583","https://openalex.org/W2991636373"],"abstract_inverted_index":{"Objetivo":[0],"o":[1,105,108,130,145,160,169,214,231,242],"objetivo":[2],"do":[3,12,14,78,100,115,162,196,201,207,285],"estudo":[4,116,264],"foi":[5,85,133,147,239],"avaliar":[6,181],"a":[7,10,184,194,260,288],"efic\u00e1cia":[8],"e":[9,22,26,107,135,153,175,188,220,251,292],"seguran\u00e7a":[11,141,252],"tratamento":[13,46,143,167,243],"Transtorno":[15,79],"de":[16,18,33,36,41,54,62,80,82,93,95,166,173,212,246,262,277],"d\u00e9ficit":[17,81],"aten\u00e7\u00e3o/hiperatividade":[19,83],"em":[20,29,51,236],"crian\u00e7as":[21,38,118],"adolescentes":[23],"com":[24,39,47,91,97,122,144,168,193,230,248,255,274],"epilepsia":[25,256],"crises":[27,157,187,224,278,296],"epil\u00e9pticas":[28,158,225],"atividade.":[30],"M\u00e9todos":[31],"22":[32],"um":[34,52,263],"total":[35],"75":[37],"m\u00e9dia":[40],"idade":[42],"(11,4\u00b1":[43],"3,7)":[44],"recebendo":[45],"drogas":[48],"antiepil\u00e9ticas,":[49],"atendidas":[50],"centro":[53],"atendimento":[55],"terci\u00e1rio":[56],"para":[57,137,180,241,279],"epilepsia,":[58],"tiveram":[59],"os":[60,98,111,189,281],"crit\u00e9rios":[61,99],"inclus\u00e3o":[63],"no":[64,142],"estudo,":[65],"apresentando":[66],"pelo":[67,226],"menos":[68],"uma":[69,88],"crise":[70],"epil\u00e9ptica":[71],"nos":[72,199,253],"\u00faltimos":[73],"tr\u00eas":[74,112],"meses.":[75],"O":[76,234],"diagnostico":[77],"(TDAH)":[84],"realizado":[86],"por":[87],"entrevista":[89],"cl\u00ednica":[90],"identifica\u00e7\u00e3o":[92],"sintomas":[94,200,245],"acordo":[96],"DSM-IV.":[101],"Tamb\u00e9m":[102],"foram":[103,119,177,203],"realizados":[104],"Kiddie-SADS":[106],"SNAP-IV.":[109,208],"Durante":[110],"meses":[113,128],"iniciais":[114],"as":[117],"tratadas":[120],"apenas":[121,268],"F\u00e1rmacos":[123],"antiepil\u00e9pticos":[124],"(FAE).":[125],"Nos":[126],"3":[127],"restantes":[129],"Metilfenidato":[131],"(MFD)":[132],"iniciado":[134],"ajustado":[136],"doses":[138],"terap\u00eauticas.":[139],"A":[140,210],"MFD":[146,286],"avaliada":[148],"pelas":[149],"mudan\u00e7as":[150,182],"na":[151,154,218,221,290,293],"frequ\u00eancia":[152,219,276,291],"gravidade":[155,185,222,294],"das":[156,186,223,295],"comparando":[159],"per\u00edodo":[161,165],"baseline":[163],"ao":[164],"MFD.":[170,197,232],"As":[171],"escalas":[172],"HASS":[174],"Barkley":[176],"utilizadas,":[178],"respectivamente,":[179],"sobre":[183,287],"efeitos":[190],"adversos":[191],"provocados":[192],"prescri\u00e7\u00e3o":[195],"Melhora":[198],"TDAH":[202],"avaliadas":[204],"pelos":[205],"escores":[206],"Resultados":[209],"an\u00e1lise":[211],"todo":[213],"grupo":[215],"demonstrou":[216],"melhora":[217],"efeito":[227,284],"da":[228],"interven\u00e7\u00e3o":[229],"Conclus\u00e3o":[233],"MFD,":[235],"baixa":[237],"dose,":[238],"efetivo":[240],"dos":[244],"TDAH,":[247],"boa":[249],"tolerabilidade":[250],"pacientes":[254],"ativa.":[257],"\u00c9":[258],"necess\u00e1rio":[259],"realiza\u00e7\u00e3o":[261],"duplo":[265],"cego":[266],"envolvendo":[267],"sujeitos":[269],"que":[270],"t\u00eam":[271],"epilepsias":[272],"refrat\u00e1rias":[273],"elevada":[275],"confirmar":[280],"resultados":[282],"deste":[283],"redu\u00e7\u00e3o":[289],"epil\u00e9pticas.":[297]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}