{"id":"https://openalex.org/W2291571622","doi":"https://doi.org/10.1093/jac/dkw047","title":"Comment on: Antifungal therapy: drug\u2013drug interactions at your fingertips","display_name":"Comment on: Antifungal therapy: drug\u2013drug interactions at your fingertips","publication_year":2016,"publication_date":"2016-03-03","ids":{"openalex":"https://openalex.org/W2291571622","doi":"https://doi.org/10.1093/jac/dkw047","mag":"2291571622","pmid":"https://pubmed.ncbi.nlm.nih.gov/26944925"},"language":"en","primary_location":{"id":"doi:10.1093/jac/dkw047","doi":"https://doi.org/10.1093/jac/dkw047","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/dkw047","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"letter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038195917","display_name":"Jennifer S. Bartholomew","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jennifer S. Bartholomew","raw_affiliation_strings":["Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK jennifer.bartholomew@manchester.ac.uk","Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK jennifer.bartholomew@manchester.ac.uk","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Susan Banfield","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Susan Banfield","raw_affiliation_strings":["Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030165757","display_name":"Graham T. Atherton","orcid":"https://orcid.org/0000-0002-7425-3153","observed_orcids":["https://orcid.org/0000-0002-7425-3153"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Graham T. Atherton","raw_affiliation_strings":["Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083752740","display_name":"David W. Denning","orcid":"https://orcid.org/0000-0001-5626-2251","observed_orcids":["https://orcid.org/0000-0001-5626-2251","https://orcid.org/0000-0002-0955-0151"]},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David W. Denning","raw_affiliation_strings":["Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Centre for Respiratory & Allergy, University of Manchester Institute of Inflammation & Repair, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"National Aspergillosis Centre, University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5038195917"],"corresponding_institution_ids":["https://openalex.org/I28407311"],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"71","issue":"7","first_page":"2062.1","last_page":"2062"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.6377000212669373,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.6377000212669373,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.10830000042915344,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.06809999793767929,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.8479999899864197},{"id":"https://openalex.org/keywords/drug-drug-interactions","display_name":"drug-drug interactions","score":0.9980000257492065},{"id":"https://openalex.org/keywords/adverse-drug-interactions","display_name":"adverse drug interactions","score":0.8259999752044678},{"id":"https://openalex.org/keywords/mobile-application","display_name":"mobile application","score":0.9779999852180481},{"id":"https://openalex.org/keywords/clinical-decision-support","display_name":"clinical decision support","score":0.6449999809265137}],"concepts":[{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.7945505380630493},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.6659443378448486},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5544843673706055},{"id":"https://openalex.org/C2991737395","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal drug","level":3,"score":0.5275000333786011},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5136250853538513},{"id":"https://openalex.org/C2909919671","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal drugs","level":3,"score":0.48707297444343567},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.41990137100219727},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.10505950450897217}],"mesh":[{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004347","descriptor_name":"Drug Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006296","descriptor_name":"Health Services","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/jac/dkw047","doi":"https://doi.org/10.1093/jac/dkw047","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/dkw047","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:26944925","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26944925","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Letter"},{"id":"pmh:oai:open-archive.highwire.org:jac:71/7/2062","doi":null,"is_oa":false,"landing_page_url":"http://jac.oxfordjournals.org/cgi/content/short/71/7/2062","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2117712600"],"related_works":["https://openalex.org/W3160493166","https://openalex.org/W2378381709","https://openalex.org/W2117712600","https://openalex.org/W4247535454","https://openalex.org/W3139491089","https://openalex.org/W2146922556","https://openalex.org/W2058261141","https://openalex.org/W3206046197","https://openalex.org/W2329026339","https://openalex.org/W4235539940"],"abstract_inverted_index":{"Sir,":[0],"We":[1],"are":[2,114,122,142,165,176],"writing":[3],"in":[4,85,146,150],"response":[5],"to":[6,57,71,95,171],"an":[7],"article":[8,26],"entitled":[9],"\u2018Antifungal":[10,120],"therapy:":[11],"drug\u2013drug":[12,32],"interactions":[13,33],"at":[14,137],"your":[15],"fingertips\u2019,":[16],"which":[17,78,105],"was":[18,79],"published":[19],"online":[20,49,84],"on":[21],"8":[22],"November":[23],"2015.1":[24],"The":[25,67,129],"highlights":[27],"the":[28,44,51,59,132,151,154],"compilation":[29],"of":[30,46,53,143,153,183,186],"adverse":[31],"(DDIs)":[34],"with":[35,102,200],"antifungal":[36,65,103],"medicines":[37],"as":[38],"a":[39,47,54,73,184],"knowledge":[40],"database.":[41],"They":[42],"describe":[43],"construction":[45],"database":[48,133],"and":[50,64,75,81,131,149,158,160,180,196],"development":[52],"smartphone":[55,97],"app":[56,155],"access":[58],"data":[60,89],"for":[61,99,124,178],"paired":[62],"DDIs":[63,101,199],"drugs.":[66],"paper":[68],"has":[69],"omitted":[70,93],"mention":[72],"similar":[74,88],"pre-existing":[76],"database,":[77],"developed":[80],"made":[82],"available":[83,108,123],"2012,":[86],"using":[87],"sources.2":[90],"It":[91],"also":[92,166],"reference":[94],"two":[96],"apps":[98,130],"assessing":[100],"medicines,":[104],"have":[106,134,190],"been":[107,135],"since":[109],"early":[110],"2013.3,4":[111],"All":[112],"these":[113],"free":[115],"resources;":[116],"both":[117],"apps,":[118],"named":[119],"Interactions\u2019,":[121],"Android":[125],"or":[126],"iOS":[127],"platforms.":[128],"presented":[136],"several":[138],"international":[139],"conferences.5,6":[140],"There":[141],"course":[144],"differences":[145],"some":[147,167],"content":[148],"presentation":[152],"by":[156],"Lempers":[157],"Br\u00fcggemann1":[159],"our":[161],"apps,3,4":[162],"but":[163],"there":[164],"other":[168],"important":[169,177],"points":[170],"highlight:":[172],"Antifungal":[173],"DDI":[174],"databases":[175],"clinicians":[179],"patients,":[181],"since,":[182],"total":[185],"2116":[187],"interactions,":[188],"we":[189],"identified":[191],"409":[192],"severe,":[193],"976":[194],"moderate":[195],"731":[197],"mild":[198],"antifungals.":[201]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}