{"id":"https://openalex.org/W2291453904","doi":null,"title":"IDENTIFICA\u00c7\u00c3O MOLECULAR E CARACTERIZA\u00c7\u00c3O FENOT\u00cdPICA E GENOT\u00cdPICA DA PRODU\u00c7\u00c3O DE BIOFILME EM ISOLADOS DE Candida spp DO HOSPITAL DAS CL\u00cdNICAS DE BOTUCATU, UNESP.","display_name":"IDENTIFICA\u00c7\u00c3O MOLECULAR E CARACTERIZA\u00c7\u00c3O FENOT\u00cdPICA E GENOT\u00cdPICA DA PRODU\u00c7\u00c3O DE BIOFILME EM ISOLADOS DE Candida spp DO HOSPITAL DAS CL\u00cdNICAS DE BOTUCATU, UNESP.","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2291453904","mag":"2291453904"},"language":"pt","primary_location":{"id":"mag:2291453904","doi":null,"is_oa":false,"landing_page_url":"https://repositorio.unesp.br/bitstream/handle/11449/108424/000736352.pdf?sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021902021","display_name":"Ariane Cristina Mendes de Oliveira Bruder Nascimento","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ariane Cristina Mendes de Oliveira Bruder Nascimento","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5021902021"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12668","display_name":"Yeasts and Rust Fungi Studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candida","display_name":"Candida","score":0.847000002861023},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.8669999837875366},{"id":"https://openalex.org/keywords/candida-parapsilosis","display_name":"Candida parapsilosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.8949999809265137},{"id":"https://openalex.org/keywords/candida-species-identification","display_name":"Candida species identification","score":0.8399999737739563},{"id":"https://openalex.org/keywords/group-i-introns","display_name":"group I introns","score":0.781000018119812},{"id":"https://openalex.org/keywords/antifungal-susceptibility","display_name":"antifungal susceptibility","score":0.9129999876022339},{"id":"https://openalex.org/keywords/invasive-candidiasis","display_name":"invasive candidiasis","score":0.8119999766349792},{"id":"https://openalex.org/keywords/hospital-infection-control","display_name":"hospital infection control","score":0.6079999804496765},{"id":"https://openalex.org/keywords/chromogenic-media","display_name":"chromogenic media","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C2779443200","wikidata":"https://www.wikidata.org/wiki/Q144068","display_name":"Candida parapsilosis","level":3,"score":0.8052479028701782},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6073356866836548},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5766322612762451},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.5705648064613342},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5458198189735413},{"id":"https://openalex.org/C2780558435","wikidata":"https://www.wikidata.org/wiki/Q3491700","display_name":"Fungemia","level":3,"score":0.449100524187088},{"id":"https://openalex.org/C97669555","wikidata":"https://www.wikidata.org/wiki/Q4118435","display_name":"Molecular epidemiology","level":4,"score":0.4379723370075226},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.436028391122818},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.28541433811187744},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15838155150413513},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1015360951423645}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2291453904","doi":null,"is_oa":false,"landing_page_url":"https://repositorio.unesp.br/bitstream/handle/11449/108424/000736352.pdf?sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W1485298008","https://openalex.org/W1535701124","https://openalex.org/W1921586209","https://openalex.org/W1965096012","https://openalex.org/W1971330935","https://openalex.org/W1972692992","https://openalex.org/W1972870818","https://openalex.org/W1977576819","https://openalex.org/W1978466336","https://openalex.org/W1981052166","https://openalex.org/W1987565613","https://openalex.org/W1988396233","https://openalex.org/W1990109619","https://openalex.org/W2003672769","https://openalex.org/W2012150744","https://openalex.org/W2022114264","https://openalex.org/W2026009239","https://openalex.org/W2030456354","https://openalex.org/W2033429308","https://openalex.org/W2047133769","https://openalex.org/W2049505636","https://openalex.org/W2064518489","https://openalex.org/W2067409920","https://openalex.org/W2068413360","https://openalex.org/W2071847689","https://openalex.org/W2072169421","https://openalex.org/W2074177031","https://openalex.org/W2089543309","https://openalex.org/W2091049152","https://openalex.org/W2091529802","https://openalex.org/W2091661775","https://openalex.org/W2093198885","https://openalex.org/W2097026648","https://openalex.org/W2100452980","https://openalex.org/W2110612528","https://openalex.org/W2112458089","https://openalex.org/W2120644786","https://openalex.org/W2121177222","https://openalex.org/W2122836009","https://openalex.org/W2123116500","https://openalex.org/W2125570838","https://openalex.org/W2125848302","https://openalex.org/W2125859998","https://openalex.org/W2126599529","https://openalex.org/W2127535744","https://openalex.org/W2128955189","https://openalex.org/W2129006376","https://openalex.org/W2129009794","https://openalex.org/W2130515584","https://openalex.org/W2132340274","https://openalex.org/W2133826036","https://openalex.org/W2134687901","https://openalex.org/W2134693978","https://openalex.org/W2136869823","https://openalex.org/W2137959581","https://openalex.org/W2138947616","https://openalex.org/W2139421104","https://openalex.org/W2140697913","https://openalex.org/W2141025633","https://openalex.org/W2143839871","https://openalex.org/W2145804339","https://openalex.org/W2148104357","https://openalex.org/W2151757612","https://openalex.org/W2155895327","https://openalex.org/W2166552420","https://openalex.org/W2169653839","https://openalex.org/W2169735925","https://openalex.org/W2416459517"],"related_works":["https://openalex.org/W7051824993","https://openalex.org/W189414203","https://openalex.org/W3127877213","https://openalex.org/W2594816822","https://openalex.org/W2156520099","https://openalex.org/W2802130070","https://openalex.org/W2333556414","https://openalex.org/W3015603396","https://openalex.org/W2575677824","https://openalex.org/W2893212659"],"abstract_inverted_index":{"1":[0],"Over":[1],"the":[2,12,54,80,93,100,104,111,145,153,177,197,203,211,222,259,279,289],"last":[3],"decade,":[4],"there":[5],"have":[6,31],"been":[7],"important":[8,34],"changes":[9],"in":[10,62,98,134,176,258],"2":[11],"epidemiology":[13,55],"of":[14,36,48,56,103,137,147,160,170,199,207,217,264,278],"Candida":[15,29,58,90,162,183,265],"infections":[16,39],"and":[17,65,83,124,140,144,190,224,232,239,243,294],"antifungal":[18],"agents":[19],"used":[20,87],"to":[21,52,78,88,92,109,118,125,151,196,250,273],"treat":[22],"these":[23],"3":[24],"infections.":[25],"In":[26],"recent":[27],"years,":[28],"species":[30,59,94,154,184],"emerged":[32],"as":[33,115,117],"causes":[35],"4":[37],"invasive":[38],"mainly":[40],"among":[41],"immunocompromised":[42],"patients.":[43],"The":[44,74,179,215,267],"principal":[45],"aim":[46],"5":[47],"this":[49,122],"study":[50],"was":[51,286],"evaluate":[53,110],"infectious":[57],"6":[60],"isolated":[61,166],"our":[63],"hospital":[64,70],"accordingly":[66],"supply":[67],"data":[68],"for":[69],"infection":[71],"control.":[72],"7":[73],"other":[75],"aims":[76],"were":[77,165,174,186,210,237,245],"compare":[79],"traditional,":[81],"automated":[82,223,244],"molecular":[84,129,226,251],"8":[85],"methods":[86,236],"identify":[89],"isolates":[91],"level":[95],"current":[96],"available":[97],"9":[99],"Clinical":[101],"Hospital":[102],"Boucatu":[105],"Medical":[106],"School,":[107],"UNESP,":[108],"drug":[112],"10":[113],"susceptibility":[114,283],"well":[116],"biofilm":[119,135],"production":[120,136],"by":[121,127,288],"yeasts":[123],"characterize,":[126],"11":[128],"tools,":[130],"several":[131],"genes":[132],"involved":[133],"C.":[138,141,155,187,191,208],"albicans":[139,188,209],"12":[142],"parapsilosis":[143,193],"use":[146],"group":[148,200],"I":[149,201],"introns":[150],"genotype":[152,205],"albicans.":[156],"A":[157,206],"13":[158],"total":[159],"196":[161],"strains":[163,296],"that":[164],"from":[167],"blood":[168],"specimens":[169],"14":[171],"hospitalized":[172],"patients":[173],"included":[175],"study.":[178],"most":[180,212],"15":[181],"common":[182],"identified":[185],"(39,3-44,4%)":[189],"16":[192],"(33,2-42,3%).":[194],"According":[195],"insertion":[198],"introns,":[202],"17":[204],"frequent":[213],"(74%).":[214],"evaluation":[216],"18":[218],"traditional":[219],"phenotypic":[220,235],"methods,":[221],"some":[225],"revealed":[227],"good":[228],"19":[229],"agreement":[230],"(>80%)":[231],"since":[233],"both":[234],"simple":[238],"cost":[240],"20":[241],"effective":[242],"few":[246],"time-consuming":[247],"when":[248],"compared":[249],"21":[252],"techniques,":[253],"they":[254],"should":[255],"be":[256,271],"considered":[257],"routine":[260],"lab":[261],"identification":[262],"22":[263],"species.":[266],"chromogenic":[268],"media":[269],"must":[270],"employed":[272],"avoid":[274],"23":[275],"misinterpretations,":[276],"independently":[277],"method":[280,292],"used.":[281],"Antifungal":[282],"24":[284],"testing":[285],"performed":[287],"reference":[290],"microdilution":[291],"(CLSI)":[293],"all":[295],"25":[297]},"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}