{"id":"https://openalex.org/W2290967913","doi":null,"title":"UV Resistance and Photoreactivation of Extremophiles from High-Altitude Andean Lakes","display_name":"UV Resistance and Photoreactivation of Extremophiles from High-Altitude Andean Lakes","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2290967913","mag":"2290967913"},"language":"en","primary_location":{"id":"pmh:oai:americanae.aecid.es:3837169","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/1765","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"http://purl.org/coar/resource_type/c_6501"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11336/1765","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040946395","display_name":"Virginia Helena Albarrac\u00edn","orcid":"https://orcid.org/0000-0002-4316-0720","observed_orcids":["https://orcid.org/0000-0002-4316-0720"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Virginia Helena Albarrac\u00edn","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4316-0720","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040909240","display_name":"Wolfgang G\u00e4rtner","orcid":"https://orcid.org/0000-0002-6898-7011","observed_orcids":["https://orcid.org/0000-0002-6898-7011"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wolfgang G\u00e4rtner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6898-7011","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5079553754","display_name":"Mar\u00eda Eugenia Far\u00edas","orcid":"https://orcid.org/0000-0002-2771-8915","observed_orcids":["https://orcid.org/0000-0002-2771-8915"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mar\u0131\u0301a Eugenia Far\u0131\u0301as","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2771-8915","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2635,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.58099443,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12180","display_name":"Polar Research and Ecology","score":0.361299991607666,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12180","display_name":"Polar Research and Ecology","score":0.361299991607666,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.20499999821186066,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.04899999871850014,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uv-b-resistance","display_name":"UV-B resistance","score":0.843999981880188},{"id":"https://openalex.org/keywords/photoreactivation","display_name":"photoreactivation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/extremophiles","display_name":"extremophiles","score":0.8709999918937683},{"id":"https://openalex.org/keywords/photolyase","display_name":"photolyase","score":0.8199999928474426},{"id":"https://openalex.org/keywords/photoreceptors","display_name":"photoreceptors","score":0.7540000081062317},{"id":"https://openalex.org/keywords/uv-induced-dna-damage","display_name":"UV-induced DNA damage","score":0.7080000042915344},{"id":"https://openalex.org/keywords/fad-binding","display_name":"FAD binding","score":0.6290000081062317},{"id":"https://openalex.org/keywords/protein-structure","display_name":"protein structure","score":0.6039999723434448},{"id":"https://openalex.org/keywords/photobiology","display_name":"photobiology","score":0.6520000100135803},{"id":"https://openalex.org/keywords/bioprospecting","display_name":"bioprospecting","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C165204475","wikidata":"https://www.wikidata.org/wiki/Q424241","display_name":"Photolyase","level":4,"score":0.6650199890136719},{"id":"https://openalex.org/C205458427","wikidata":"https://www.wikidata.org/wiki/Q206912","display_name":"Extremophile","level":4,"score":0.5282166004180908},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.48293420672416687},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.46274617314338684},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.4585106670856476},{"id":"https://openalex.org/C6350597","wikidata":"https://www.wikidata.org/wiki/Q339495","display_name":"Altitude (triangle)","level":2,"score":0.41168057918548584},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3509829640388489},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.32757124304771423},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.2666108012199402},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.06925186514854431},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C27911776","wikidata":"https://www.wikidata.org/wiki/Q834023","display_name":"Thermophile","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:americanae.aecid.es:3837169","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/1765","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/92023","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/92023","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/1765","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/1765","pdf_url":"http://hdl.handle.net/11336/1765","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"mag:2290967913","doi":null,"is_oa":false,"landing_page_url":"http://ri.conicet.gov.ar/handle/11336/1765","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:americanae.aecid.es:3837169","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/1765","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:CONICET Digital (CONICET)","raw_type":"http://purl.org/coar/resource_type/c_6501"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2290967913.pdf","grobid_xml":"https://content.openalex.org/works/W2290967913.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W183744588","https://openalex.org/W1494400290","https://openalex.org/W1679971907","https://openalex.org/W1680724326","https://openalex.org/W1857141999","https://openalex.org/W1867447038","https://openalex.org/W1980883327","https://openalex.org/W1991593993","https://openalex.org/W1993318049","https://openalex.org/W1998840349","https://openalex.org/W2002655620","https://openalex.org/W2005307781","https://openalex.org/W2013119258","https://openalex.org/W2014439357","https://openalex.org/W2016224329","https://openalex.org/W2019282077","https://openalex.org/W2025482838","https://openalex.org/W2036786683","https://openalex.org/W2039585182","https://openalex.org/W2040951800","https://openalex.org/W2051248004","https://openalex.org/W2056350783","https://openalex.org/W2061019965","https://openalex.org/W2067139494","https://openalex.org/W2071416281","https://openalex.org/W2075588167","https://openalex.org/W2080758881","https://openalex.org/W2083966995","https://openalex.org/W2088641101","https://openalex.org/W2089911941","https://openalex.org/W2091299578","https://openalex.org/W2092563530","https://openalex.org/W2098736553","https://openalex.org/W2103892786","https://openalex.org/W2120544856","https://openalex.org/W2129214067","https://openalex.org/W2130149293","https://openalex.org/W2132427279","https://openalex.org/W2137351605","https://openalex.org/W2139597538","https://openalex.org/W2141843759","https://openalex.org/W2143897202","https://openalex.org/W2145301542","https://openalex.org/W2158757371","https://openalex.org/W2161832812","https://openalex.org/W2162398331","https://openalex.org/W2162914394","https://openalex.org/W2165390912","https://openalex.org/W2171781763","https://openalex.org/W2238269907","https://openalex.org/W4242289525"],"related_works":["https://openalex.org/W2902590618","https://openalex.org/W2080758881","https://openalex.org/W1989142777","https://openalex.org/W2193462074","https://openalex.org/W2007489473","https://openalex.org/W2006784914","https://openalex.org/W4220821795","https://openalex.org/W3182891248","https://openalex.org/W2613976247","https://openalex.org/W2587216369"],"abstract_inverted_index":{"He":[0],"HAAL":[1,89,311],"are":[2],"natural":[3],"laboratories":[4],"for":[5,167,241,281,316,325],"exploring":[6,317],"and":[7,16,83,96,163,171,197,251,273,324],"monitoring":[8],"in":[9,45,121,141,173,206,248,252],"situ":[10],"interactions":[11],"between":[12],"the":[13,17,30,34,38,41,88,118,122,135,142,174,178,183,210,213,256,262,266,276,298,310,326],"geophysical":[14],"environment":[15],"dynamics":[18],"of":[19,40,115,124,137,144,212,221,233,237,259,270,279,291,328],"biodiversity.":[20],"Solar":[21],"irradiation":[22,75],"(including":[23],"high":[24,352],"UV-B":[25,74],"doses)":[26],"is":[27,51,228,245,294,344],"without":[28],"doubt":[29],"factor":[31],"that":[32,54,149,202],"puts":[33],"greatest":[35],"pressure":[36],"on":[37,160,335,350],"ecology":[39],"microbial":[42],"communities":[43],"thriving":[44],"these":[46,132],"shallow":[47],"lakes.":[48],"Thus,":[49],"it":[50],"not":[52],"surprising":[53],"~100":[55],"strains":[56],"with":[57,72,107,275,331],"intrinsic":[58],"UV-B-resistance":[59],"have":[60,67,110],"been":[61],"isolated":[62],"from":[63,185,354],"HAAL.":[64],"These":[65],"organisms":[66],"developed":[68],"strategies":[69],"to":[70,76,80,94,98,182,204,209,255,300,346],"cope":[71],"strong":[73,155],"avoid":[77],"severe":[78],"UV-B-damage":[79],"proteins,":[81],"lipids":[82],"DNA.":[84],"Hence,":[85],"microbiota":[86],"at":[87,297],"may":[90],"harbor":[91],"special":[92],"mechanisms":[93],"sense":[95],"respond":[97],"such":[99],"a":[100,112,138,193,198,229,286,351,355],"ubiquitous":[101],"resource,":[102],"i.e.,":[103],"light.":[104],"In":[105],"accordance":[106,208],"this,":[108],"we":[109,176],"encountered":[111],"rich":[113],"diversity":[114],"photoreceptors":[116,133],"within":[117],"cryptochrome-photolyase":[119],"family":[120],"genomes":[123],"three":[125],"UV-B-resistant":[126],"extremophiles.":[127],"Of":[128],"particular":[129],"importance":[130],"among":[131],"was":[134],"finding":[136],"photolyase-coding":[139],"sequence":[140,161],"genome":[143],"Acinetobacter":[145],"sp.":[146],"Ver3":[147,249,280],"strain":[148],"displayed":[150],"efficient":[151,277],"photoreactivation":[152],"ability":[153,278],"after":[154],"UV-B-induced":[156],"DNA":[157],"damage.":[158],"Based":[159],"alignments":[162],"secondary":[164],"structure":[165,191,211],"predictions":[166],"this":[168,271,292],"novel":[169,318,329],"photolyase,":[170,250],"entries":[172],"PDB,":[175],"found":[177],"highest":[179],"three-dimensional":[180],"similarity":[181],"photolyase":[184],"E.":[186,214],"coli":[187,215],"(PDB":[188],"1DNPA).":[189],"The":[190,217,235,305],"revealed":[192],"proximal":[194],"alpha-beta":[195],"domain,":[196],"distal":[199],"helical":[200],"domain":[201],"binds":[203],"FAD":[205],"full":[207],"photolyase.":[216],"N-terminal":[218],"anti-parallel":[219],"bundle":[220],"beta":[222],"sheets":[223],"enclosed":[224],"by":[225,322],"alpha":[226],"helices":[227],"typical":[230],"folding":[231],"motif":[232],"photolyases.":[234],"chain":[236],"three-tryptophan":[238],"residues":[239],"instrumental":[240],"electron":[242],"transfer":[243],"reaction":[244],"also":[246],"conserved":[247],"close":[253],"proximity":[254],"isoalloxazine":[257],"ring":[258],"FAD.":[260],"All":[261],"former":[263],"findings":[264],"support":[265],"putative":[267],"CPD-photolyase":[268],"property":[269],"protein,":[272],"agree":[274],"repairing":[282],"CPD":[283],"lesions.":[284],"Nevertheless,":[285],"more":[287],"detailed":[288],"functional":[289],"characterization":[290],"\"extremoenzyme\"":[293],"being":[295],"conducted":[296],"moment":[299],"clarify":[301],"its":[302],"repair":[303],"function.":[304],"scenario":[306],"pictured":[307],"herein":[308],"makes":[309],"microorganisms":[312],"excellent":[313],"test":[314],"cases":[315],"enzymatic":[319],"functions":[320],"driven":[321],"light,":[323],"bioprospection":[327],"molecules":[330],"potential":[332],"biotechnological":[333],"applications":[334],"energy":[336],"conversion,":[337],"biomedicine":[338],"or":[339],"industry.":[340],"This":[341],"brief":[342],"overview":[343],"intended":[345],"\"shine\"":[347],"scientific":[348],"light":[349],"window":[353],"quite":[356],"unexplored,":[357],"exotic":[358],"environment,":[359],"which":[360],"otherwise":[361],"constitutes":[362],"an":[363],"exceptional":[364],"outdoor":[365],"photobiology":[366],"lab.":[367]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}