{"id":"https://openalex.org/W2290035591","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.753.11","title":"CORRELATION OF DR\u03b21*1501, DQ\u03b21*0602 DONOR ALLELIC HAPLOTYPE WITH HUMORAL ANTIBODY EPISODES OF ACUTE RENAL ALLOGRAFT REJECTION","display_name":"CORRELATION OF DR\u03b21*1501, DQ\u03b21*0602 DONOR ALLELIC HAPLOTYPE WITH HUMORAL ANTIBODY EPISODES OF ACUTE RENAL ALLOGRAFT REJECTION","publication_year":2010,"publication_date":"2010-04-01","ids":{"openalex":"https://openalex.org/W2290035591","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.753.11","mag":"2290035591"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.24.1_supplement.753.11","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.753.11","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.24.1_supplement.753.11","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060987813","display_name":"Venkat K.R. Mannam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Venkat Krishna Reddy Mannam","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017916044","display_name":"Taryn N. Green","orcid":"https://orcid.org/0000-0001-9527-5960","observed_orcids":["https://orcid.org/0000-0001-9527-5960"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taryn Green","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Morgan Cowan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Morgan Cowan","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027329478","display_name":"Joshua Goodin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Goodin","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072416990","display_name":"Robert E. Lewis","orcid":"https://orcid.org/0000-0002-3616-2971","observed_orcids":["https://orcid.org/0000-0002-3616-2971","https://orcid.org/0009-0005-0177-220X"]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Lewis","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057457134","display_name":"Steven A. Bigler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven Bigler","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108591334","display_name":"Julius M. Cruse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julius Cruse","raw_affiliation_strings":["Immunopathology, University of Mississippi Medical Center, Jackson, MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Immunopathology, University of Mississippi Medical Center, Jackson, MS","institution_ids":["https://openalex.org/I29606459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I29606459"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36456212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hla-class-ii-haplotypes","display_name":"HLA class II haplotypes","score":0.7049999833106995},{"id":"https://openalex.org/keywords/acute-renal-allograft-rejection","display_name":"acute renal allograft rejection","score":0.9610000252723694},{"id":"https://openalex.org/keywords/c4d-staining","display_name":"C4d staining","score":0.8339999914169312},{"id":"https://openalex.org/keywords/donor-recipient-hla-mismatch","display_name":"donor-recipient HLA mismatch","score":0.9049999713897705},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.6330000162124634},{"id":"https://openalex.org/keywords/hla-typing","display_name":"HLA typing","score":0.35499998927116394}],"concepts":[{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.7874367833137512},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.7125958204269409},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.635738730430603},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5768923163414001},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.5677669048309326},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.4854629635810852},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4383489191532135},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40130212903022766},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38434919714927673},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.31081467866897583},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20614343881607056},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19677358865737915},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13987693190574646}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.24.1_supplement.753.11","doi":"https://doi.org/10.1096/fasebj.24.1_supplement.753.11","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.24.1_supplement.753.11","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1999854415","https://openalex.org/W2032390370","https://openalex.org/W2418236321","https://openalex.org/W4415115256","https://openalex.org/W2158007408","https://openalex.org/W2004495070","https://openalex.org/W1999503574","https://openalex.org/W2014351561","https://openalex.org/W2113342039","https://openalex.org/W2024569972"],"abstract_inverted_index":{"The":[0,33],"present":[1],"investigation":[2],"was":[3,135],"designed":[4],"to":[5,81,151],"show":[6],"the":[7,39,44,48,130,160,165,169,180],"effect":[8],"of":[9,38,50,59,74,89,97,109,122,142,153,171,175,187,203],"molecular":[10,119],"HLA":[11],"class":[12],"II":[13],"DR":[14,147],"and":[15,21,178,190],"DQ":[16],"allelic":[17],"differences":[18],"between":[19],"donor":[20,45,64,78,106,128,166,189],"recipient":[22,191],"on":[23],"humoral":[24,51,67,83,172,204],"antibody":[25,52,68,84,173],"rejection":[26,205],"identified":[27],"by":[28,116],"C4d":[29,183],"peritubular":[30],"capillary":[31],"staining.":[32,184],"hypothesis":[34],"is":[35,199],"that":[36,56,159],"expression":[37],"DR\u03b21*1501,":[40,161],"DQ\u03b21*0602":[41,162],"allele":[42,134,163],"in":[43,137,164],"kidney":[46,167],"increases":[47,168],"likelihood":[49],"rejection.":[53,87],"We":[54,104],"found":[55],"67":[57],"%(n=18)":[58],"DR15":[60,75],"and/or":[61],"DQ6":[62],"haplotype":[63,77,107],"kidneys":[65,79],"induce":[66,82],"renal":[69,85],"allograft":[70,86],"rejection;":[71],"35%":[72,141],"(n=40)":[73],"and/orDQ6":[76],"failed":[80],"41%":[88],"C4d+":[90,111,124,143],"recipients":[91,99,115,125,144],"had":[92,100,126,145],"donors":[93,101],"with":[94,102,112,129],"DR15;":[95],"15%":[96],"C4d\u2212":[98,114,139,154],"HLA\u2010DR15.":[103],"compared":[105,150],"alleles":[108],"4":[110,123],"6":[113],"high":[117],"resolution":[118],"typing;":[120],"3":[121],"a":[127,200],"DR\u03b21*1501/DQ\u03b21*0602":[131],"allele.":[132],"This":[133],"absent":[136],"all":[138],"donors.":[140],"2":[146],"mismatches":[148],"when":[149],"33%":[152],"recipients.":[155],"Our":[156],"results,":[157],"suggest":[158],"risk":[170],"episodes":[174],"acute":[176],"rejection,":[177],"signals":[179],"need":[181],"for":[182],"Future":[185],"analysis":[186],"additional":[188],"haplotypes":[192],"will":[193],"establish":[194],"whether":[195],"or":[196],"not":[197],"this":[198],"useful":[201],"predictor":[202],"episodes.":[206]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}