{"id":"https://openalex.org/W2288959800","doi":"https://doi.org/10.1097/ta.0000000000001002","title":"Acute traumatic coagulopathy in a critically injured pediatric population","display_name":"Acute traumatic coagulopathy in a critically injured pediatric population","publication_year":2016,"publication_date":"2016-02-17","ids":{"openalex":"https://openalex.org/W2288959800","doi":"https://doi.org/10.1097/ta.0000000000001002","mag":"2288959800","pmid":"https://pubmed.ncbi.nlm.nih.gov/26886002"},"language":"en","primary_location":{"id":"doi:10.1097/ta.0000000000001002","doi":"https://doi.org/10.1097/ta.0000000000001002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ta.0000000000001002","pdf_url":null,"source":{"id":"https://openalex.org/S4210177186","display_name":"The Journal of Trauma: Injury, Infection, and Critical Care","issn_l":"2163-0755","issn":["2163-0755","2163-0763"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Trauma and Acute Care Surgery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039321004","display_name":"Christine M. Leeper","orcid":"https://orcid.org/0000-0002-8561-8760","observed_orcids":["https://orcid.org/0000-0002-8561-8760","https://orcid.org/0000-0001-9902-0340"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine M. Leeper","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center; and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania; and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center; and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania; and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210130600","https://openalex.org/I4210134769","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034765888","display_name":"Matthew Kutcher","orcid":"https://orcid.org/0000-0003-4566-5359","observed_orcids":["https://orcid.org/0000-0003-4566-5359"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Kutcher","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047578758","display_name":"Isam W. Nasr","orcid":"https://orcid.org/0000-0002-1848-5259","observed_orcids":["https://orcid.org/0000-0002-1848-5259"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Isam Nasr","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048468393","display_name":"Christine McKenna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christine McKenna","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062076820","display_name":"Timothy R. Billiar","orcid":"https://orcid.org/0000-0002-2949-0811","observed_orcids":["https://orcid.org/0000-0002-2949-0811"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Billiar","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029058133","display_name":"Matthew D. Neal","orcid":"https://orcid.org/0000-0001-8931-6236","observed_orcids":["https://orcid.org/0000-0001-8931-6236"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew Neal","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109191035","display_name":"Jason L. Sperry","orcid":"https://orcid.org/0000-0003-3917-6479","observed_orcids":["https://orcid.org/0000-0003-3917-6479"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Sperry","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110009048","display_name":"Barbara Anne Gaines","orcid":"https://orcid.org/0000-0002-9257-169X","observed_orcids":["https://orcid.org/0000-0002-9257-169X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210130600","display_name":"Children's Hospital of Pittsburgh","ror":"https://ror.org/03763ep67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara A. Gaines","raw_affiliation_strings":["From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","email: [email\u00a0protected]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of General Surgery and Trauma (C.M.L., M.K., T.B., M.N., J.S.), Department of Surgery, University of Pittsburgh Medical Center","institution_ids":["https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"and Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Address for reprints: Barbara A. Gaines, MD, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh of UPMC, 7th Floor, Faculty Pavilion, One Children's Hospital Dr, 4401 Penn Ave, Pittsburgh, PA 15224","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Children's Hospital of Pittsburgh of UPMC (C.M.L., C.M., B.A.G.), Pittsburgh, Pennsylvania","institution_ids":["https://openalex.org/I4210130600","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Pediatric Surgery (I.N.), The Johns Hopkins Hospital, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]},{"raw_affiliation_string":"Submitted: December 2, 2015, Revised: January 21, 2016, Accepted: January 27, 2016, Published online: February 18, 2016","institution_ids":[]},{"raw_affiliation_string":"This study was presented at the 29th annual meeting of the Eastern Association for the Surgery of Trauma, January 12\u201316, 2016, in San Antonio, Texas","institution_ids":[]},{"raw_affiliation_string":"email: [email\u00a0protected]","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.0611,"has_fulltext":false,"cited_by_count":68,"citation_normalized_percentile":{"value":0.95822763,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"81","issue":"1","first_page":"34","last_page":"41"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11467","display_name":"Trauma and Emergency Care Studies","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-traumatic-coagulopathy","display_name":"acute traumatic coagulopathy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pediatric-trauma","display_name":"pediatric trauma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/international-normalized-ratio","display_name":"international normalized ratio","score":0.8659999966621399},{"id":"https://openalex.org/keywords/mortality-prediction","display_name":"mortality prediction","score":0.890999972820282},{"id":"https://openalex.org/keywords/intensive-care-unit-admission","display_name":"intensive care unit admission","score":0.7089999914169312},{"id":"https://openalex.org/keywords/plasma-transfusion","display_name":"plasma transfusion","score":0.7929999828338623},{"id":"https://openalex.org/keywords/coagulopathy-correction","display_name":"coagulopathy correction","score":0.6259999871253967},{"id":"https://openalex.org/keywords/trauma-registry","display_name":"trauma registry","score":0.32199999690055847},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7059999704360962},{"id":"https://openalex.org/keywords/hemorrhagic-shock","display_name":"hemorrhagic shock","score":0.5569999814033508},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.5709999799728394},{"id":"https://openalex.org/keywords/acidosis","display_name":"acidosis","score":0.5490000247955322},{"id":"https://openalex.org/keywords/hypothermia","display_name":"hypothermia","score":0.8529999852180481},{"id":"https://openalex.org/keywords/hypotension","display_name":"hypotension","score":0.949999988079071},{"id":"https://openalex.org/keywords/injury-severity","display_name":"injury severity","score":0.6899999976158142}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9078786373138428},{"id":"https://openalex.org/C2779936836","wikidata":"https://www.wikidata.org/wiki/Q890200","display_name":"Coagulopathy","level":2,"score":0.7195614576339722},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.6083046197891235},{"id":"https://openalex.org/C85004164","wikidata":"https://www.wikidata.org/wiki/Q1089964","display_name":"Injury Severity Score","level":4,"score":0.5754822492599487},{"id":"https://openalex.org/C43346845","wikidata":"https://www.wikidata.org/wiki/Q8057732","display_name":"Youden's J statistic","level":3,"score":0.5695403218269348},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.5400288105010986},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4836186468601227},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4710614085197449},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.46988561749458313},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.44529256224632263},{"id":"https://openalex.org/C2777981362","wikidata":"https://www.wikidata.org/wiki/Q7159235","display_name":"Pediatric trauma","level":4,"score":0.4413529634475708},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.4341717064380646},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.40655314922332764},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33095884323120117},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.2829045057296753},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.2547500729560852},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001778","descriptor_name":"Blood Coagulation Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014947","descriptor_name":"Wounds and Injuries","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014947","descriptor_name":"Wounds and Injuries","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D015278","descriptor_name":"Intensive Care Units, Pediatric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015601","descriptor_name":"Injury Severity Score","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019934","descriptor_name":"International Normalized Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/ta.0000000000001002","doi":"https://doi.org/10.1097/ta.0000000000001002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ta.0000000000001002","pdf_url":null,"source":{"id":"https://openalex.org/S4210177186","display_name":"The Journal of Trauma: Injury, Infection, and Critical Care","issn_l":"2163-0755","issn":["2163-0755","2163-0763"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Trauma and Acute Care Surgery","raw_type":"journal-article"},{"id":"pmid:26886002","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26886002","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of trauma and acute care surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W118344571","https://openalex.org/W1490725941","https://openalex.org/W1549306192","https://openalex.org/W1969167508","https://openalex.org/W1971410089","https://openalex.org/W1991438089","https://openalex.org/W1992034786","https://openalex.org/W1994534010","https://openalex.org/W1994974585","https://openalex.org/W1996709257","https://openalex.org/W1999519140","https://openalex.org/W2013125286","https://openalex.org/W2021308489","https://openalex.org/W2022938012","https://openalex.org/W2038905950","https://openalex.org/W2041395932","https://openalex.org/W2046989562","https://openalex.org/W2064521505","https://openalex.org/W2065793617","https://openalex.org/W2071283644","https://openalex.org/W2071495228","https://openalex.org/W2071853226","https://openalex.org/W2073977342","https://openalex.org/W2075304757","https://openalex.org/W2079715879","https://openalex.org/W2083761317","https://openalex.org/W2085143218","https://openalex.org/W2085167072","https://openalex.org/W2087156568","https://openalex.org/W2088106697","https://openalex.org/W2112657827","https://openalex.org/W2118208696","https://openalex.org/W2126714811","https://openalex.org/W2144080918","https://openalex.org/W2146837707","https://openalex.org/W2152575748","https://openalex.org/W2164840394","https://openalex.org/W2165574572","https://openalex.org/W2264772667","https://openalex.org/W2265809849","https://openalex.org/W2316441890","https://openalex.org/W2319900543","https://openalex.org/W4248762695"],"related_works":["https://openalex.org/W3025101607","https://openalex.org/W2792694855","https://openalex.org/W2580824058","https://openalex.org/W2123189282","https://openalex.org/W2465538617","https://openalex.org/W2941324138","https://openalex.org/W4411188242","https://openalex.org/W2085143218","https://openalex.org/W2041395932","https://openalex.org/W2062133114"],"abstract_inverted_index":{"BACKGROUND:":[0],"While":[1],"our":[2,51],"understanding":[3],"of":[4,34,50,108,119,155,168,181,192,280,333],"acute":[5],"traumatic":[6],"coagulopathy":[7],"(ATC)":[8],"in":[9,227,288,301,306,339],"adults":[10],"is":[11,18,326],"advancing,":[12],"the":[13,32,71,318],"pediatric":[14,309,340],"literature":[15],"on":[16,37],"ATC":[17,38,334],"limited.":[19],"Children":[20],"have":[21],"a":[22,47,106,278,285,307],"unique":[23],"injury":[24,126],"profile":[25],"and":[26,82,88,129,141,149,172,199,240,298,335,347],"physiologic":[27],"response":[28],"to":[29,56,65,70,94,115,196,253,328],"trauma;":[30],"however,":[31,312],"impact":[33],"this":[35],"phenomenon":[36],"has":[39],"not":[40,262,316],"been":[41],"fully":[42],"elucidated.":[43],"METHODS:":[44],"We":[45],"performed":[46,135],"retrospective":[48],"review":[49],"trauma":[52,60,310,341],"registry":[53],"from":[54],"2005":[55],"2014.":[57],"Level":[58],"1":[59],"patients":[61,157],"age":[62,271],"0":[63],"year":[64],"17":[66],"years":[67],"requiring":[68],"admission":[69,79,100,166,179,291],"intensive":[72],"care":[73],"unit":[74],"were":[75,134,158,250,261,268],"included.":[76],"Variables":[77],"included":[78],"vital":[80],"signs":[81],"laboratory":[83],"studies,":[84],"product":[85,313],"transfusion,":[86],"injuries,":[87],"mortality.":[89,109],"Youden":[90,185],"index":[91,186],"was":[92,113,204,211,231],"used":[93,114],"determine":[95,116],"optimum":[96,188],"cutoff":[97,189],"point":[98],"for":[99,122,137,224,337],"international":[101],"normalized":[102],"ratio":[103],"(INR)":[104],"as":[105,144,146,277],"predictor":[107],"Logistic":[110],"regression":[111,228],"modeling":[112],"independent":[117],"predictors":[118,226],"mortality":[120,140,202,215,305],"adjusting":[121],"hypotension,":[123],"hypothermia,":[124],"acidosis,":[125],"severity,":[127],"hemorrhage,":[128],"head":[130],"injury.":[131],"\u03c7":[132],"tests":[133],"evaluating":[136],"association":[138],"between":[139,147],"24-hour":[142],"INR":[143,150,167,180,191,210,236,242,256,274,294,302,319],"well":[145],"transfusion":[148,314],"correction.":[151],"RESULTS:":[152],"A":[153],"total":[154],"776":[156],"analyzed:":[159],"29.2%":[160],"(n":[161,174,206],"=":[162,175,207,265],"227)":[163],"had":[164,177],"an":[165,178],"1.3":[169,193],"or":[170,183,194,321],"greater,":[171],"13.3%":[173],"103)":[176],"1.5":[182],"greater.":[184],"demonstrated":[187],"at":[190,237,295],"greater":[195],"distinguish":[197],"survivors":[198],"nonsurvivors.":[200],"Overall":[201],"rate":[203],"11.1%":[205],"86).":[208],"Elevated":[209,290],"independently":[212],"associated":[213,233],"with":[214,234,258],"(odds":[216],"ratio,":[217],"3.77;":[218],"p":[219],"<":[220],"0.001)":[221],"after":[222],"controlling":[223],"other":[225],"modeling.":[229],"Death":[230],"also":[232],"elevated":[235,293],"24":[238,296],"hours":[239],"worsening":[241],"trend":[243,300,320],"over":[244],"time.":[245],"Patients":[246],"who":[247,260],"received":[248],"plasma":[249],"equally":[251],"likely":[252,275],"normalize":[254],"their":[255],"compared":[257],"those":[259],"transfused":[263],"(p":[264],"nonsignificant).":[266],"Findings":[267],"consistent":[269],"across":[270],"groups.":[272],"CONCLUSION:":[273],"serves":[276],"marker":[279],"systemic":[281],"dysregulation":[282],"rather":[283],"than":[284],"treatment":[286],"target":[287],"ATC.":[289],"INR,":[292],"hours,":[297],"overall":[299],"strongly":[303],"predict":[304],"diverse":[308],"population;":[311],"did":[315],"influence":[317],"clinical":[322],"outcome.":[323],"Further":[324],"research":[325],"warranted":[327],"evaluate":[329],"potential":[330],"upstream":[331],"mediators":[332],"targets":[336],"intervention":[338],"patients.":[342],"LEVEL":[343],"OF":[344],"EVIDENCE:":[345],"Prognostic":[346],"epidemiologic":[348],"study,":[349],"level":[350],"III.":[351]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
