{"id":"https://openalex.org/W2288436115","doi":"https://doi.org/10.3109/10253890.2016.1146672","title":"Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: influence of gender, smoking, and BMI","display_name":"Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: influence of gender, smoking, and BMI","publication_year":2016,"publication_date":"2016-01-26","ids":{"openalex":"https://openalex.org/W2288436115","doi":"https://doi.org/10.3109/10253890.2016.1146672","mag":"2288436115","pmid":"https://pubmed.ncbi.nlm.nih.gov/26809721"},"language":"en","primary_location":{"id":"doi:10.3109/10253890.2016.1146672","doi":"https://doi.org/10.3109/10253890.2016.1146672","is_oa":true,"landing_page_url":"https://doi.org/10.3109/10253890.2016.1146672","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/10253890.2016.1146672?needAccess=true&role=button","source":{"id":"https://openalex.org/S54143609","display_name":"Stress","issn_l":"1025-3890","issn":["1025-3890","1029-2160","1607-8888"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stress","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.3109/10253890.2016.1146672?needAccess=true&role=button","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110186224","display_name":"Carly E. Herbison","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Carly E. Herbison","raw_affiliation_strings":["School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103179705","display_name":"David Henley","orcid":"https://orcid.org/0000-0003-0194-7194","observed_orcids":["https://orcid.org/0000-0003-0194-7194"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]},{"id":"https://openalex.org/I2802220196","display_name":"Sir Charles Gairdner Hospital","ror":"https://ror.org/01hhqsm59","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800882159","https://openalex.org/I2802220196","https://openalex.org/I4210133657","https://openalex.org/I4396570646"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"David Henley","raw_affiliation_strings":["Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, WA, Australia,","School of Medicine and Pharmacology, The University of Western Australia, Perth, WA, Australia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, WA, Australia,","institution_ids":["https://openalex.org/I2802220196"]},{"raw_affiliation_string":"School of Medicine and Pharmacology, The University of Western Australia, Perth, WA, Australia,","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073224659","display_name":"Julie Marsh","orcid":"https://orcid.org/0000-0001-8984-6907","observed_orcids":["https://orcid.org/0000-0001-8984-6907"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Julie Marsh","raw_affiliation_strings":["School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014560207","display_name":"Helen C. Atkinson","orcid":"https://orcid.org/0000-0002-2172-3780","observed_orcids":["https://orcid.org/0000-0002-2172-3780"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Helen Atkinson","raw_affiliation_strings":["School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050844526","display_name":"John P. Newnham","orcid":"https://orcid.org/0000-0001-9983-7457","observed_orcids":["https://orcid.org/0000-0001-9983-7457"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"John P. Newnham","raw_affiliation_strings":["School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,","institution_ids":["https://openalex.org/I177877127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071397090","display_name":"Stephen G. Matthews","orcid":"https://orcid.org/0000-0002-9654-9940","observed_orcids":["https://orcid.org/0000-0002-9654-9940"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Stephen G. Matthews","raw_affiliation_strings":["Department of Physiology, Department of Obstetrics and Gynecology & Department of Medicine, University of Toronto, Toronto, ON, Canada, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Department of Obstetrics and Gynecology & Department of Medicine, University of Toronto, Toronto, ON, Canada, and","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032904180","display_name":"Stephen James Lye","orcid":"https://orcid.org/0000-0002-3305-4406","observed_orcids":["https://orcid.org/0000-0002-3305-4406"]},"institutions":[{"id":"https://openalex.org/I1291836623","display_name":"Mount Sinai Hospital","ror":"https://ror.org/05deks119","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1291836623","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Stephen J. Lye","raw_affiliation_strings":["Mount Sinai Hospital, The Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mount Sinai Hospital, The Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada","institution_ids":["https://openalex.org/I1291836623","https://openalex.org/I210557978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076433645","display_name":"Craig Edward Pennell","orcid":"https://orcid.org/0000-0002-0937-6165","observed_orcids":["https://orcid.org/0000-0002-0937-6165"]},"institutions":[{"id":"https://openalex.org/I177877127","display_name":"The University of Western Australia","ror":"https://ror.org/047272k79","country_code":"AU","type":"education","lineage":["https://openalex.org/I177877127"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Craig E. Pennell","raw_affiliation_strings":["School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Women\u2019s and Infants\u2019 Health, The University of Western Australia, Perth, WA, Australia,","institution_ids":["https://openalex.org/I177877127"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5110186224"],"corresponding_institution_ids":["https://openalex.org/I177877127"],"apc_list":{"value":2895,"currency":"EUR","value_usd":3175},"apc_paid":null,"fwci":2.7629,"has_fulltext":true,"cited_by_count":49,"citation_normalized_percentile":{"value":0.88125344,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"19","issue":"2","first_page":"139","last_page":"150"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-stress-reaction","display_name":"acute stress response","score":0.9919999837875366},{"id":"https://openalex.org/keywords/trier-social-stress-test","display_name":"Trier Social Stress Test","score":0.9710000157356262},{"id":"https://openalex.org/keywords/nonresponders","display_name":"non-responders","score":0.9210000038146973},{"id":"https://openalex.org/keywords/cortisol","display_name":"cortisol","score":0.7689999938011169},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.8240000009536743},{"id":"https://openalex.org/keywords/salivary-cortisol","display_name":"salivary cortisol","score":0.9729999899864197},{"id":"https://openalex.org/keywords/plasma-cortisol","display_name":"plasma cortisol","score":0.875},{"id":"https://openalex.org/keywords/gender-differences","display_name":"gender differences","score":0.7599999904632568},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9800000190734863},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.968999981880188},{"id":"https://openalex.org/keywords/oral-contraceptive-use","display_name":"oral contraceptive use","score":0.7279999852180481},{"id":"https://openalex.org/keywords/menstrual-cycle-phase","display_name":"menstrual cycle phases","score":0.9860000014305115},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.9120000004768372},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.5139999985694885}],"concepts":[{"id":"https://openalex.org/C2778597338","wikidata":"https://www.wikidata.org/wiki/Q7841444","display_name":"Trier social stress test","level":4,"score":0.789306640625},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.7342281937599182},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6503399610519409},{"id":"https://openalex.org/C2780586474","wikidata":"https://www.wikidata.org/wiki/Q332428","display_name":"Overweight","level":3,"score":0.5752080082893372},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5736268758773804},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5539683699607849},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.47593334317207336},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.43006858229637146},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.38066497445106506},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.36284905672073364},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.33389824628829956},{"id":"https://openalex.org/C78604142","wikidata":"https://www.wikidata.org/wiki/Q1640582","display_name":"Fight-or-flight response","level":3,"score":0.24152854084968567},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11597311496734619},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006854","descriptor_name":"Hydrocortisone","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D007030","descriptor_name":"Hypothalamo-Hypophyseal System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010913","descriptor_name":"Pituitary-Adrenal System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3109/10253890.2016.1146672","doi":"https://doi.org/10.3109/10253890.2016.1146672","is_oa":true,"landing_page_url":"https://doi.org/10.3109/10253890.2016.1146672","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/10253890.2016.1146672?needAccess=true&role=button","source":{"id":"https://openalex.org/S54143609","display_name":"Stress","issn_l":"1025-3890","issn":["1025-3890","1029-2160","1607-8888"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stress","raw_type":"journal-article"},{"id":"pmid:26809721","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26809721","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stress (Amsterdam, Netherlands)","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/3f5c29ea-ddd9-48be-9076-16e1a16b7d14","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/3f5c29ea-ddd9-48be-9076-16e1a16b7d14","pdf_url":null,"source":{"id":"https://openalex.org/S4306402492","display_name":"UWA Profiles and Research Repository (UWA)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Herbison, C E, Henley, D, Marsh, J, Atkinson, H, Newnham, J, Matthews, S G, Lye, S J & Pennell, C 2016, 'Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: Influence of gender, smoking, and BMI', Stress, vol. 19, no. 2, pp. 139-150. https://doi.org/10.3109/10253890.2016.1146672","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:espace.curtin.edu.au:20.500.11937/62218","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.11937/62218","pdf_url":null,"source":{"id":"https://openalex.org/S4306401790","display_name":"eSpace (Curtin University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205640436","host_organization_name":"Curtin University","host_organization_lineage":["https://openalex.org/I205640436"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3109/10253890.2016.1146672","doi":"https://doi.org/10.3109/10253890.2016.1146672","is_oa":true,"landing_page_url":"https://doi.org/10.3109/10253890.2016.1146672","pdf_url":"https://www.tandfonline.com/doi/pdf/10.3109/10253890.2016.1146672?needAccess=true&role=button","source":{"id":"https://openalex.org/S54143609","display_name":"Stress","issn_l":"1025-3890","issn":["1025-3890","1029-2160","1607-8888"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320449","host_organization_name":"Informa","host_organization_lineage":["https://openalex.org/P4310320449"],"host_organization_lineage_names":["Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stress","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G5388449085","display_name":null,"funder_award_id":"MOP82893","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"}],"funders":[{"id":"https://openalex.org/F4320315885","display_name":"Australian Government","ror":"https://ror.org/0314h5y94"},{"id":"https://openalex.org/F4320318419","display_name":"Universit\u00e4t Trier","ror":"https://ror.org/02778hg05"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2288436115.pdf","grobid_xml":"https://content.openalex.org/works/W2288436115.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W170411931","https://openalex.org/W898822149","https://openalex.org/W1497034610","https://openalex.org/W1529795543","https://openalex.org/W1572208191","https://openalex.org/W1792110071","https://openalex.org/W1968787277","https://openalex.org/W1971188127","https://openalex.org/W1998742722","https://openalex.org/W2004293180","https://openalex.org/W2015463486","https://openalex.org/W2019062333","https://openalex.org/W2019397169","https://openalex.org/W2021395577","https://openalex.org/W2022227125","https://openalex.org/W2041223478","https://openalex.org/W2051714598","https://openalex.org/W2052787253","https://openalex.org/W2054147233","https://openalex.org/W2059247207","https://openalex.org/W2060220801","https://openalex.org/W2064453031","https://openalex.org/W2065292219","https://openalex.org/W2075627423","https://openalex.org/W2084038751","https://openalex.org/W2085495638","https://openalex.org/W2086902152","https://openalex.org/W2092880670","https://openalex.org/W2100798060","https://openalex.org/W2101451224","https://openalex.org/W2103141157","https://openalex.org/W2104129218","https://openalex.org/W2107347271","https://openalex.org/W2110243778","https://openalex.org/W2110948307","https://openalex.org/W2117077354","https://openalex.org/W2118936082","https://openalex.org/W2121588628","https://openalex.org/W2122246933","https://openalex.org/W2130597643","https://openalex.org/W2137402534","https://openalex.org/W2139284888","https://openalex.org/W2141804913","https://openalex.org/W2144171217","https://openalex.org/W2144961120","https://openalex.org/W2145161166","https://openalex.org/W2145998662","https://openalex.org/W2148022513","https://openalex.org/W2151929259","https://openalex.org/W2156579478","https://openalex.org/W2161754592","https://openalex.org/W2164593127","https://openalex.org/W2320692076","https://openalex.org/W2326396329","https://openalex.org/W2576406766"],"related_works":["https://openalex.org/W2144961120","https://openalex.org/W4281904079","https://openalex.org/W2100798060","https://openalex.org/W6986768922","https://openalex.org/W7096596174","https://openalex.org/W2065292219","https://openalex.org/W2139623579","https://openalex.org/W3195472361","https://openalex.org/W1548404776","https://openalex.org/W4206555758"],"abstract_inverted_index":{"Dysregulation":[0],"of":[1,13,38,75,103,113,145,241],"the":[2,11,45,48,109,122,146,175,207,245],"biological":[3],"stress":[4,22,39,104,111],"response":[5,23,40,105,112],"system":[6],"has":[7,244],"been":[8,42,65],"implicated":[9],"in":[10,21,32,44,68,221,228],"development":[12],"psychological,":[14],"metabolic,":[15],"and":[16,58,95,100,129,137,143,165,237,252,254],"cardiovascular":[17],"disease.":[18],"Whilst":[19],"changes":[20],"are":[24],"often":[25],"quantified":[26],"as":[27],"an":[28],"increase":[29],"or":[30,158],"decrease":[31],"cortisol":[33,131],"levels,":[34],"three":[35],"different":[36],"patterns":[37,139,177,243],"have":[41,63],"reported":[43],"literature":[46],"for":[47,204,259],"Trier":[49],"Social":[50],"Stress":[51],"Test":[52],"(TSST)":[53],"(reactive-responders":[54],"(RR),":[55],"anticipatory-responders":[56],"(AR)":[57],"non-responders":[59],"(NR)).":[60],"However,":[61],"these":[62,242],"never":[64],"systematically":[66],"analyzed":[67,108],"a":[69,118,199,222,257],"large":[70],"population-based":[71],"cohort.":[72],"The":[73,239],"aims":[74],"this":[76],"study":[77],"were":[78,133,150,168,183],"to":[79,84,153,171,186,230,247],"examine":[80],"factors":[81],"that":[82,220],"contribute":[83],"TSST":[85,208],"variation":[86],"(gender,":[87],"oral":[88],"contraceptive":[89],"use,":[90],"menstrual":[91],"cycle":[92],"phase,":[93],"smoking,":[94,236],"BMI)":[96],"using":[97,121],"traditional":[98],"methods":[99],"novel":[101,200],"analyses":[102],"patterns.":[106],"We":[107],"acute":[110],"798,":[114],"18-year-old":[115],"participants":[116],"from":[117],"community-based":[119],"cohort":[120],"TSST.":[123],"Plasma":[124],"adrenocorticotrophic":[125],"hormone,":[126],"plasma":[127],"cortisol,":[128],"salivary":[130],"levels":[132],"quantified.":[134],"RR,":[135],"AR,":[136],"NR":[138,155,173,190],"comprised":[140],"56.6%,":[141],"26.2%,":[142],"17.2%":[144],"cohort,":[147,225],"respectively.":[148],"Smokers":[149],"more":[151,184],"likely":[152,170,185],"be":[154,172,187],"than":[156,174,189,213],"(RR":[157],"AR;":[159],"adjusted,":[160],"p":[161,179,192],"<":[162,180],"0.05).":[163,181,194],"Overweight":[164],"obese":[166],"subjects":[167],"less":[169],"other":[176,231],"(adjusted,":[178,191],"Males":[182],"RR":[188],"=":[193],"In":[195],"addition,":[196],"we":[197],"present":[198],"AUC":[201],"measure":[202],"(AUCR),":[203],"use":[205],"when":[206],"baseline":[209],"concentration":[210],"is":[211],"higher":[212],"later":[214],"time":[215],"points.":[216],"These":[217],"results":[218],"show":[219],"young":[223],"adult":[224,250],"stress-response":[226],"patterns,":[227],"addition":[229],"parameters":[232],"vary":[233,248],"with":[234,249],"gender,":[235],"BMI.":[238],"distribution":[240],"potential":[246],"health":[251],"disease":[253],"may":[255],"represent":[256],"biomarker":[258],"future":[260],"investigation.":[261]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
