{"id":"https://openalex.org/W22874248","doi":null,"title":"Population structure of the Bacillus cereus group","display_name":"Population structure of the Bacillus cereus group","publication_year":2006,"publication_date":"2006-04-01","ids":{"openalex":"https://openalex.org/W22874248","mag":"22874248"},"language":"en","primary_location":{"id":"pmh:hdl:10068/934592","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10068/934592","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111865337","display_name":"Margaret Barker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Margaret Barker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5111865337"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11515","display_name":"Bacillus and Francisella bacterial research","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacillus-cereus-group","display_name":"Bacillus cereus group","score":0.9980000257492065},{"id":"https://openalex.org/keywords/population-structure","display_name":"population structure","score":0.8309999704360962},{"id":"https://openalex.org/keywords/species-delimitation","display_name":"species delimitation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/multilocus-sequence-typing","display_name":"multilocus sequence typing","score":0.9049999713897705},{"id":"https://openalex.org/keywords/bacillus-anthracis","display_name":"Bacillus anthracis","score":0.8759999871253967},{"id":"https://openalex.org/keywords/bacillus-thuringiensis","display_name":"Bacillus thuringiensis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/bacillus-cereus","display_name":"Bacillus cereus","score":0.9160000085830688},{"id":"https://openalex.org/keywords/bacillus-mycoides","display_name":"Bacillus mycoides","score":0.9240000247955322},{"id":"https://openalex.org/keywords/bacillus-pseudomycoides","display_name":"Bacillus pseudomycoides","score":0.9710000157356262},{"id":"https://openalex.org/keywords/bacillus-weihenstephanensis","display_name":"Bacillus weihenstephanensis","score":0.972000002861023},{"id":"https://openalex.org/keywords/clonal-architecture","display_name":"clonal architecture","score":0.828000009059906},{"id":"https://openalex.org/keywords/recombination","display_name":"recombination","score":0.7820000052452087},{"id":"https://openalex.org/keywords/emetic-toxin","display_name":"emetic toxin","score":0.7289999723434448},{"id":"https://openalex.org/keywords/entomopathogenic-bacteria","display_name":"entomopathogenic bacteria","score":0.5709999799728394},{"id":"https://openalex.org/keywords/septicemia","display_name":"septicemia","score":0.7160000205039978},{"id":"https://openalex.org/keywords/serotypes","display_name":"serotypes","score":0.5490000247955322},{"id":"https://openalex.org/keywords/housekeeping-genes","display_name":"housekeeping genes","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C2777118263","wikidata":"https://www.wikidata.org/wiki/Q131307","display_name":"Bacillus cereus","level":3,"score":0.8348889350891113},{"id":"https://openalex.org/C2781311116","wikidata":"https://www.wikidata.org/wiki/Q83306","display_name":"Group (periodic table)","level":2,"score":0.5401591062545776},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33532005548477173},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.33490440249443054},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.22491416335105896},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11193615198135376},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08357700705528259},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.06963494420051575}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:hdl:10068/934592","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10068/934592","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"mag:22874248","doi":null,"is_oa":false,"landing_page_url":"http://www.ros.hw.ac.uk/bitstream/10399/2145/1/BarkerM_0406_sls.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":114,"referenced_works":["https://openalex.org/W145328525","https://openalex.org/W222910508","https://openalex.org/W641828379","https://openalex.org/W1501415946","https://openalex.org/W1590573769","https://openalex.org/W1601950803","https://openalex.org/W1688775979","https://openalex.org/W1883478397","https://openalex.org/W1925331805","https://openalex.org/W1934642468","https://openalex.org/W1951398891","https://openalex.org/W1960932922","https://openalex.org/W1963563104","https://openalex.org/W1963772772","https://openalex.org/W1969464199","https://openalex.org/W1970209609","https://openalex.org/W1970651230","https://openalex.org/W1971636785","https://openalex.org/W1975859179","https://openalex.org/W1976496738","https://openalex.org/W1977039424","https://openalex.org/W1980016131","https://openalex.org/W1981563187","https://openalex.org/W1984303898","https://openalex.org/W1984702361","https://openalex.org/W1989966631","https://openalex.org/W1992299051","https://openalex.org/W1993087283","https://openalex.org/W1995357664","https://openalex.org/W1997915530","https://openalex.org/W1998746931","https://openalex.org/W2009972059","https://openalex.org/W2020134144","https://openalex.org/W2022527211","https://openalex.org/W2026413648","https://openalex.org/W2028998553","https://openalex.org/W2041886351","https://openalex.org/W2043107677","https://openalex.org/W2044473722","https://openalex.org/W2048285080","https://openalex.org/W2048752758","https://openalex.org/W2050523158","https://openalex.org/W2050575653","https://openalex.org/W2052903624","https://openalex.org/W2060590832","https://openalex.org/W2063993421","https://openalex.org/W2064641442","https://openalex.org/W2065311355","https://openalex.org/W2069368208","https://openalex.org/W2075371279","https://openalex.org/W2077914268","https://openalex.org/W2078064634","https://openalex.org/W2081561143","https://openalex.org/W2083587510","https://openalex.org/W2086033353","https://openalex.org/W2088313841","https://openalex.org/W2092027334","https://openalex.org/W2094617834","https://openalex.org/W2095724872","https://openalex.org/W2095789339","https://openalex.org/W2095925877","https://openalex.org/W2102300942","https://openalex.org/W2103842828","https://openalex.org/W2105333758","https://openalex.org/W2106428264","https://openalex.org/W2106882534","https://openalex.org/W2106928585","https://openalex.org/W2107847732","https://openalex.org/W2108643808","https://openalex.org/W2108679420","https://openalex.org/W2111205680","https://openalex.org/W2111531935","https://openalex.org/W2112704704","https://openalex.org/W2112760436","https://openalex.org/W2113153814","https://openalex.org/W2113515344","https://openalex.org/W2120682398","https://openalex.org/W2121297340","https://openalex.org/W2121861720","https://openalex.org/W2122108794","https://openalex.org/W2122145390","https://openalex.org/W2122538488","https://openalex.org/W2124898405","https://openalex.org/W2125302790","https://openalex.org/W2128789445","https://openalex.org/W2130641564","https://openalex.org/W2130887804","https://openalex.org/W2133457164","https://openalex.org/W2135479403","https://openalex.org/W2139111510","https://openalex.org/W2139471932","https://openalex.org/W2139678543","https://openalex.org/W2142503351","https://openalex.org/W2144403475","https://openalex.org/W2145240901","https://openalex.org/W2145282362","https://openalex.org/W2145809152","https://openalex.org/W2147834333","https://openalex.org/W2151371624","https://openalex.org/W2151511015","https://openalex.org/W2153983434","https://openalex.org/W2155062978","https://openalex.org/W2155641525","https://openalex.org/W2156434383","https://openalex.org/W2159308620","https://openalex.org/W2159798931","https://openalex.org/W2159961063","https://openalex.org/W2161987668","https://openalex.org/W2161991622","https://openalex.org/W2164741622","https://openalex.org/W2166642025","https://openalex.org/W2169812063","https://openalex.org/W2285775483","https://openalex.org/W3217097258"],"related_works":["https://openalex.org/W7098279134","https://openalex.org/W2161987668","https://openalex.org/W2288343205","https://openalex.org/W7000832543","https://openalex.org/W2288384588","https://openalex.org/W4412331641","https://openalex.org/W2414079960","https://openalex.org/W7100493480","https://openalex.org/W2146090923","https://openalex.org/W4252804126"],"abstract_inverted_index":{"The":[0,467],"Bacillus":[1],"cereus":[2,54,75,148,198,215,275,308],"group":[3,76,149,284],"of":[4,39,72,114,139,145,153,194,210,222,224,273,285,306,342,361,433],"bacteria":[5],"comprises":[6],"B.":[7,9,11,13,15,18,33,45,53,74,147,195,197,201,211,214,225,227,230,233,265,274,287,307,343,362,434,436,438,440,442,445],"anthracis,":[8,196,435],"cereus,":[10,226,437],"mycoides,":[12,439],"pseudomycoides,":[14,441],"thuringiensis":[16,46,212,288,344,363,377,443],"and":[17,43,52,60,69,98,130,176,199,213,229,251,260,268,295,317,328,330,376,382,389,396,419,444,447],"weihenstephanensis.":[19,231],"Species":[20],"status":[21,142,432],"has":[22],"been":[23,311],"allocated":[24],"to":[25,30,102,181,334,347,411,421,472],"these":[26],"taxa":[27],"largely":[28,178],"according":[29],"pathogenic":[31],"properties.":[32],"anthracis":[34,266],"is":[35,47,55,456],"the":[36,73,115,136,146,160,182,240,258,269,297,301,320,367,412,429],"causative":[37],"agent":[38],"anthrax":[40],"in":[41,65,84,247,292],"ungulates":[42],"humans.":[44,66],"primarily":[48],"an":[49,448],"insect":[50],"pathogen":[51],"associated":[56],"with":[57,164,402,463,475],"food":[58],"poisoning":[59],"occasionally":[61],"soft":[62],"tissue":[63],"infections":[64,316],"One":[67],"hundred":[68],"forty-six":[70],"strains":[71,175,216,223,235,267,272,289,357],"were":[77,100,187,236,245,323,331,345,354,364,378,384,391,470],"examined":[78,365],"by":[79,366],"multilocus":[80],"sequence":[81,106,162,454],"typing":[82],"(MLST)":[83],"which":[85],"partial":[86],"sequences":[87],"for":[88,109,122,143,167],"seven":[89],"housekeeping":[90],"genes":[91,414],"(glpF,":[92],"gmk,":[93],"ilvD,":[94],"pta,":[95],"pur,":[96],"pycA":[97],"tpi)":[99],"generated":[101],"provide":[103],"a":[104,177,207,335,349],"definitive":[105],"type":[107],"(ST)":[108],"each":[110,168],"strain.":[111],"Statistical":[112],"analyses":[113],"data":[116,163,455],"using":[117],"pairwise":[118],"comparisons":[119],"between":[120,174,263,423],"groups":[121],"(i)":[123],"Fst":[124],"(gene":[125],"flow),":[126],"(ii)":[127],"shared":[128,255],"mutations":[129,256],"(iii)":[131],"fixed":[132,261],"differences":[133,262],"confirmed":[134],"that":[135,309],"present":[137],"designation":[138],"separate":[140,430],"species":[141,431],"members":[144],"was":[150,191,220,290],"inappropriate.":[151],"Comparison":[152],"neighbour":[154],"joining":[155],"(NJ)":[156],"trees":[157,165],"derived":[158],"from":[159,239,313,358],"concatenated":[161],"constructed":[166],"allele":[169],"individually":[170],"indicated":[171],"limited":[172],"recombination":[173],"clonal":[179,283,337,350,386],"structure":[180,351],"group.":[183,338],"Three":[184],"major":[185],"clades":[186,249,326,462],"recovered:":[188],"clade":[189,204,218,280,293],"1":[190,250,327],"made":[192],"up":[193],"rare":[200],"ringiensis":[202],"strains;":[203],"2":[205,252,294],"comprised":[206],"heterogeneous":[208],"mixture":[209],"while":[217,352,387],"3":[219],"composed":[221],"mycoides":[228],"Two":[232],"pseudomycoides":[234],"distant":[237],"outliers":[238],"main":[241,461],"tree.":[242],"Four":[243],"lineages":[244,259,469],"recognised":[246],"both":[248],"based":[253,451,458],"on":[254,319,417,452,459],"within":[257,279],"them.":[264],"emetic":[270],"toxin-producing":[271],"formed":[276],"two":[277],"clones":[278],"1.":[281],"A":[282],"entomopathogenic":[286],"identified":[291],"named":[296,471],"\u2018Sotto\u2019":[298],"lineage":[299],"(after":[300],"predicted":[302],"founder":[303],"group).":[304],"Strains":[305],"had":[310],"isolated":[312],"human":[314],"wound":[315],"septicaemia,":[318],"other":[321],"hand,":[322],"distributed":[324],"over":[325],"2,":[329],"not":[332,399,427],"restricted":[333],"particular":[336],"Similarly,":[339],"some":[340],"serotypes":[341,360],"found":[346],"have":[348],"others":[353],"heterogeneous.":[355,392],"Representative":[356],"several":[359],"RAPD":[368,397],"(random":[369],"amplified":[370],"polymorphic":[371],"DNA)":[372],"method.":[373],"Serovars":[374],"israelensis":[375],"strongly":[379],"clonal,":[380],"morrisoni":[381],"tolworthi":[383],"partially":[385],"darmstadiensis":[388],"canadensis":[390],"Serotype,":[393],"MLST":[394,425],"profile":[395],"did":[398],"always":[400],"correlate":[401],"delta-endotoxin":[403],"cry":[404,413],"gene":[405],"content.":[406],"This":[407],"may":[408],"be":[409,473],"due":[410],"being":[415],"located":[416],"plasmids":[418],"subject":[420],"transfer":[422],"strains.":[424],"does":[426],"support":[428],"weihenstephanensis":[446],"alternative":[449],"classification":[450],"DNA":[453],"proposed":[457,468],"three":[460],"nine":[464],"distinct":[465],"lineages.":[466],"consistent":[474],"current":[476],"nomenclature,":[477],"as":[478,480],"far":[479],"possible.":[481]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
