{"id":"https://openalex.org/W2287194476","doi":null,"title":"Dietary supplementation with olive oil leads to improved lipoprotein spectrum and lower n-6 PUFAs in elderly subjects.","display_name":"Dietary supplementation with olive oil leads to improved lipoprotein spectrum and lower n-6 PUFAs in elderly subjects.","publication_year":2004,"publication_date":"2004-04-01","ids":{"openalex":"https://openalex.org/W2287194476","mag":"2287194476","pmid":"https://pubmed.ncbi.nlm.nih.gov/15039655"},"language":"en","primary_location":{"id":"pmid:15039655","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15039655","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035981358","display_name":"Peter Haban","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Haban","raw_affiliation_strings":["Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia. peter_haban@yahoo.com","Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia. peter_haban@yahoo.com","institution_ids":[]},{"raw_affiliation_string":"Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066884149","display_name":"Jana Klvanov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jana Klvanova","raw_affiliation_strings":["Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039674672","display_name":"Eva Zidekova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eva Zidekova","raw_affiliation_strings":["Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063890230","display_name":"Anna Nagyov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Nagyova","raw_affiliation_strings":["Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Preventive & Clinical Medicine, Humanitarian Foundation for the Disabled, Bratislava, Slovakia","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2788,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.79826557,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"10","issue":"4","first_page":"PI49","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.5512999892234802,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.5512999892234802,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.36329999566078186,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.047600001096725464,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extra-virgin-olive-oil","display_name":"extra virgin olive oil","score":0.9150000214576721},{"id":"https://openalex.org/keywords/dietary-supplementation","display_name":"dietary supplementation","score":0.9679999947547913},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.8539999723434448},{"id":"https://openalex.org/keywords/omega-6-fatty-acids","display_name":"omega-6 fatty acids","score":0.8709999918937683},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.996999979019165},{"id":"https://openalex.org/keywords/linoleic-acid","display_name":"linoleic acid","score":0.9539999961853027},{"id":"https://openalex.org/keywords/oleic-acid","display_name":"oleic acid","score":0.7110000252723694},{"id":"https://openalex.org/keywords/mediterranean-diet","display_name":"Mediterranean diet","score":0.656000018119812},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.5299999713897705},{"id":"https://openalex.org/keywords/serum-phospholipids","display_name":"serum phospholipids","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cholesterol-ratio","display_name":"cholesterol ratio","score":0.4390000104904175}],"concepts":[{"id":"https://openalex.org/C2778962194","wikidata":"https://www.wikidata.org/wiki/Q47564","display_name":"Mediterranean diet","level":2,"score":0.8411189317703247},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.6659214496612549},{"id":"https://openalex.org/C2780809830","wikidata":"https://www.wikidata.org/wiki/Q407426","display_name":"Linoleic acid","level":3,"score":0.6198212504386902},{"id":"https://openalex.org/C2781403372","wikidata":"https://www.wikidata.org/wiki/Q207688","display_name":"Oleic acid","level":2,"score":0.6155393123626709},{"id":"https://openalex.org/C2778078955","wikidata":"https://www.wikidata.org/wiki/Q407699","display_name":"Arachidonic acid","level":3,"score":0.5845212936401367},{"id":"https://openalex.org/C2988377048","wikidata":"https://www.wikidata.org/wiki/Q93165","display_name":"Olive oil","level":2,"score":0.5822651386260986},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.5280961394309998},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.4764312207698822},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4596395790576935},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4585847854614258},{"id":"https://openalex.org/C2776091944","wikidata":"https://www.wikidata.org/wiki/Q409990","display_name":"Eicosapentaenoic acid","level":4,"score":0.44998666644096375},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.44691193103790283},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4259195327758789},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42261192202568054},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.3793220520019531},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3221193552017212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2835763692855835},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2462535798549652},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09481820464134216}],"mesh":[{"descriptor_ui":"D000069463","descriptor_name":"Olive Oil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005231","descriptor_name":"Fatty Acids, Unsaturated","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010938","descriptor_name":"Plant Oils","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016718","descriptor_name":"Arachidonic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019301","descriptor_name":"Oleic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:15039655","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15039655","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Journal Article"},{"id":"mag:2287194476","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15039655","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W121548498","https://openalex.org/W2412241351","https://openalex.org/W1995359219","https://openalex.org/W7097467047","https://openalex.org/W2304360391","https://openalex.org/W2058083533","https://openalex.org/W2072011528","https://openalex.org/W4294844944","https://openalex.org/W1964372540","https://openalex.org/W1914235052"],"abstract_inverted_index":{"BACKGROUND:":[0],"Oleic":[1],"acid,":[2],"polyphenols,":[3],"and":[4,74,101,122,138,158,163,166,224],"other":[5,42],"components":[6],"abundantly":[7],"present":[8],"in":[9,155,171,206],"olive":[10,86,118,196],"oil":[11,87,197],"are":[12,44],"thought":[13],"to":[14,23,45,135,145,190,229],"be":[15,46,211,230],"partly":[16],"responsible":[17],"for":[18,71],"the":[19,24,29,37,91,156,199,220],"antiatherogenic":[20],"effects":[21,221],"attributed":[22],"Mediterranean":[25],"diet.":[26],"One":[27],"of":[28,60,78,84,90,195,222],"expected":[30],"outcomes":[31],"is":[32,228],"a":[33,110,152],"positive":[34],"impact":[35],"on":[36,53,198],"lipoprotein":[38,200],"spectrum,":[39],"but":[40],"also":[41,151],"benefits":[43],"expected.":[47,231],"MATERIAL/METHODS:":[48],"The":[49,67,180,202],"analysis":[50],"was":[51,69,107,150],"conducted":[52],"28":[54],"outpatients":[55],"older":[56],"than":[57],"50":[58],"years":[59],"age":[61,63],"(mean":[62],"68.1,":[64],"95%CI":[65],"64.9-71.3).":[66],"supplement":[68],"taken":[70],"6":[72],"weeks":[73],"involved":[75],"daily":[76],"consumption":[77],"2":[79],"tablespoons":[80],"(approx.":[81],"20":[82],"g)":[83],"extra-virgin":[85],"as":[88,213],"part":[89],"subjects'":[92],"habitual":[93],"diets,":[94],"without":[95],"changing":[96],"their":[97],"usual":[98],"total":[99],"energy":[100],"fat":[102],"c":[103],"onsumption.":[104],"This":[105],"phase":[106],"followed":[108],"by":[109,128],"2-month":[111],"wash-out.":[112],"RESULTS:":[113],"After":[114],"dietary":[115],"supplementation":[116],"with":[117],"oil,":[119],"serum":[120,172],"total-":[121],"LDL-cholesterol":[123],"mean":[124],"concentrations":[125],"were":[126,183],"lowered":[127],"0.818":[129],"mmol/l":[130,140],"(p<0.00002;":[131],"95%":[132,142],"CI":[133,143],"-1.142":[134],"-0.493":[136],"mmol/l)":[137],"0.782":[139],"(p=0.00013;":[141],"-1.141":[144],"-0.423":[146],"mmol/l),":[147],"respectively.":[148],"There":[149],"significant":[153,204],"decline":[154],"total-to-HDL":[157],"LDL-to-HDL":[159],"cholesterol":[160],"ratios":[161],"(p<0.03":[162],"p<0.015).":[164],"Linolic":[165],"ar":[167],"achidonic":[168],"acid":[169,208],"content":[170],"phospholipids":[173],"decreased":[174],"significantly":[175],"(p<0.01":[176],"andcl":[177],"p<0.001,":[178],"respectively).":[179],"n-3":[181,226],"PUFAs":[182,227],"not":[184],"affected.":[185],"CONCLUSIONS:":[186],"These":[187],"results":[188],"point":[189],"an":[191],"overwhelmingly":[192],"beneficial":[193],"influence":[194],"spectrum.":[201],"statistically":[203],"reduction":[205],"arachidonic":[207],"may":[209],"even":[210],"regarded":[212],"clinically":[214],"desirable.":[215],"An":[216],"excellent":[217],"complementarity":[218],"between":[219],"MUFAs":[223],"long-chain":[225]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}