{"id":"https://openalex.org/W2287057795","doi":"https://doi.org/10.1007/978-1-59259-411-5_7","title":"Genomic Imprinting in Mouse Embryonic Stem and Germ Cells","display_name":"Genomic Imprinting in Mouse Embryonic Stem and Germ Cells","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W2287057795","doi":"https://doi.org/10.1007/978-1-59259-411-5_7","mag":"2287057795"},"language":"en","primary_location":{"id":"mag:2287057795","doi":"https://doi.org/10.1007/978-1-59259-411-5_7","is_oa":false,"landing_page_url":"https://link.springer.com/10.1007/978-1-59259-411-5_7","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004292678","display_name":"Jeff R. Mann","orcid":"https://orcid.org/0000-0003-0028-8692","observed_orcids":["https://orcid.org/0000-0003-0028-8692"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey R. Mann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5023474946","display_name":"Piroska E. Szab\u00f3","orcid":"https://orcid.org/0000-0001-9314-7009","observed_orcids":["https://orcid.org/0000-0001-9314-7009"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piroska E. Szab\u00f3","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9314-7009","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1653,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.54733415,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"81","last_page":"88"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11928","display_name":"Genetic Syndromes and Imprinting","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11928","display_name":"Genetic Syndromes and Imprinting","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genomic-imprinting","display_name":"genomic imprinting","score":1.0},{"id":"https://openalex.org/keywords/monoallelic-expression","display_name":"monoallelic expression","score":0.7910000085830688},{"id":"https://openalex.org/keywords/embryonic-stem-cells","display_name":"embryonic stem cells","score":0.7170000076293945},{"id":"https://openalex.org/keywords/germ-cells","display_name":"germ cells","score":0.9909999966621399},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8190000057220459},{"id":"https://openalex.org/keywords/epigenetic-inheritance","display_name":"epigenetic inheritance","score":0.6399999856948853},{"id":"https://openalex.org/keywords/germline","display_name":"germline","score":0.6869999766349792},{"id":"https://openalex.org/keywords/stem-cell-therapy","display_name":"stem cell therapy","score":0.7360000014305115},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.34200000762939453}],"concepts":[{"id":"https://openalex.org/C201492766","wikidata":"https://www.wikidata.org/wiki/Q84087","display_name":"Genomic imprinting","level":5,"score":0.8657203912734985},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7609354257583618},{"id":"https://openalex.org/C109825262","wikidata":"https://www.wikidata.org/wiki/Q1139164","display_name":"Germline","level":3,"score":0.7603188753128052},{"id":"https://openalex.org/C94715292","wikidata":"https://www.wikidata.org/wiki/Q624349","display_name":"Imprinting (psychology)","level":3,"score":0.7413336634635925},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.7375336289405823},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6740531921386719},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.6486743688583374},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.643798291683197},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5957828760147095},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5630518198013306},{"id":"https://openalex.org/C77255625","wikidata":"https://www.wikidata.org/wiki/Q402093","display_name":"Reprogramming","level":3,"score":0.5288903117179871},{"id":"https://openalex.org/C2779122487","wikidata":"https://www.wikidata.org/wiki/Q281579","display_name":"Germ cell","level":3,"score":0.5145344138145447},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4732561409473419},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.36689895391464233},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.33079054951667786}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2287057795","doi":"https://doi.org/10.1007/978-1-59259-411-5_7","is_oa":false,"landing_page_url":"https://link.springer.com/10.1007/978-1-59259-411-5_7","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":101,"referenced_works":["https://openalex.org/W89717087","https://openalex.org/W222311808","https://openalex.org/W328825372","https://openalex.org/W1486183464","https://openalex.org/W1497453049","https://openalex.org/W1518914060","https://openalex.org/W1533935872","https://openalex.org/W1591016426","https://openalex.org/W1609534144","https://openalex.org/W1643500256","https://openalex.org/W1646817159","https://openalex.org/W1669374546","https://openalex.org/W1673514954","https://openalex.org/W1829371983","https://openalex.org/W1829990018","https://openalex.org/W1887077905","https://openalex.org/W1894129931","https://openalex.org/W1959319781","https://openalex.org/W1961597426","https://openalex.org/W1962259234","https://openalex.org/W1965526087","https://openalex.org/W1966697925","https://openalex.org/W1972779402","https://openalex.org/W1973727308","https://openalex.org/W1974127834","https://openalex.org/W1975459355","https://openalex.org/W1976110788","https://openalex.org/W1976886665","https://openalex.org/W1977573876","https://openalex.org/W1977577232","https://openalex.org/W1978538506","https://openalex.org/W1981639631","https://openalex.org/W1982650546","https://openalex.org/W1985467296","https://openalex.org/W1992028127","https://openalex.org/W1992525863","https://openalex.org/W1995184255","https://openalex.org/W1995559307","https://openalex.org/W1995574948","https://openalex.org/W2002639317","https://openalex.org/W2002877822","https://openalex.org/W2005290266","https://openalex.org/W2007314953","https://openalex.org/W2013346353","https://openalex.org/W2014109329","https://openalex.org/W2025594663","https://openalex.org/W2027537562","https://openalex.org/W2032512845","https://openalex.org/W2035783896","https://openalex.org/W2036414291","https://openalex.org/W2038223191","https://openalex.org/W2041105117","https://openalex.org/W2043622843","https://openalex.org/W2044124160","https://openalex.org/W2045899482","https://openalex.org/W2047227694","https://openalex.org/W2047870452","https://openalex.org/W2049063528","https://openalex.org/W2050400423","https://openalex.org/W2057159461","https://openalex.org/W2059167536","https://openalex.org/W2061076014","https://openalex.org/W2062542552","https://openalex.org/W2067163627","https://openalex.org/W2072218174","https://openalex.org/W2074906225","https://openalex.org/W2075322953","https://openalex.org/W2085842509","https://openalex.org/W2092860994","https://openalex.org/W2097236698","https://openalex.org/W2097589091","https://openalex.org/W2097595052","https://openalex.org/W2103246764","https://openalex.org/W2107345366","https://openalex.org/W2109143388","https://openalex.org/W2109744103","https://openalex.org/W2110427132","https://openalex.org/W2114768769","https://openalex.org/W2117600128","https://openalex.org/W2124513497","https://openalex.org/W2137546188","https://openalex.org/W2141737525","https://openalex.org/W2143658931","https://openalex.org/W2149056949","https://openalex.org/W2149228985","https://openalex.org/W2156139452","https://openalex.org/W2156799279","https://openalex.org/W2159250091","https://openalex.org/W2163035954","https://openalex.org/W2163666397","https://openalex.org/W2167020978","https://openalex.org/W2168819459","https://openalex.org/W2175849508","https://openalex.org/W2184561450","https://openalex.org/W2303552151","https://openalex.org/W2340829394","https://openalex.org/W2393155497","https://openalex.org/W2400027078","https://openalex.org/W2401684706","https://openalex.org/W3167239035","https://openalex.org/W7096145306"],"related_works":["https://openalex.org/W1980689576","https://openalex.org/W2027974804","https://openalex.org/W25072721","https://openalex.org/W2137195358","https://openalex.org/W1571006575","https://openalex.org/W4388301490","https://openalex.org/W2416140607","https://openalex.org/W2057382500","https://openalex.org/W2021184952","https://openalex.org/W1969824245"],"abstract_inverted_index":{"Genomic":[0],"imprinting":[1,84],"is":[2,35,63,103],"an":[3,104],"epigenetic":[4,53],"system":[5],"determining":[6],"the":[7,21,40,57,64,89,108],"parent-of-origin-specific":[8],"monoallelic":[9,58],"expression":[10,29,41,59,80],"of":[11,14,42,60,69,93,110],"a":[12],"subset":[13],"genes,":[15],"with":[16],"imprints":[17],"being":[18],"imparted":[19],"in":[20,32,81,99,107],"germline":[22],"according":[23],"to":[24,78],"germ":[25,97],"cell":[26,47],"sex.":[27],"Monoallelic":[28],"begins":[30],"early":[31],"development":[33],"and":[34,49,91,96,114],"maintained":[36],"throughout":[37],"life,":[38],"regulating":[39],"genes":[43,62],"important":[44,52,105],"for":[45,55,119],"somatic":[46],"growth":[48],"differentiation.":[50],"An":[51],"mechanism":[54],"controlling":[56],"imprinted":[61],"differential":[65,75,79],"allelic":[66],"methylation":[67],"state":[68],"cis-acting":[70],"gene":[71],"DNA":[72],"regulatory":[73],"elements\u2014this":[74],"methy-lation":[76],"leads":[77],"trans.":[82],"Genetic":[83],"may":[85],"be":[86],"altered":[87],"during":[88],"derivation":[90],"propagation":[92],"embryonic":[94],"stem":[95,112,117],"cells":[98],"vitro":[100],"and,":[101],"therefore,":[102],"consideration":[106],"use":[109],"such":[111],"cells,":[113,118],"possibly":[115],"somatic-derived":[116],"therapy.":[120]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}