{"id":"https://openalex.org/W2286328375","doi":null,"title":"The initial treatment strategy and the long-term outcome of early rheumatoid arthritis with special interest in the FIN-RACo trial and the current Finnish practice","display_name":"The initial treatment strategy and the long-term outcome of early rheumatoid arthritis with special interest in the FIN-RACo trial and the current Finnish practice","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2286328375","mag":"2286328375"},"language":"en","primary_location":{"id":"pmh:oai:trepo.tuni.fi:10024/66907","doi":null,"is_oa":true,"landing_page_url":"https://trepo.tuni.fi/handle/10024/66907","pdf_url":"https://trepo.tuni.fi/bitstream/10024/66907/1/978-951-44-8823-8.pdf","source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"fi=V\u00e4it\u00f6skirja | en=Doctoral dissertation|"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://trepo.tuni.fi/bitstream/10024/66907/1/978-951-44-8823-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005794053","display_name":"Vappu Marianna Rantalaiho","orcid":"https://orcid.org/0000-0002-7470-3070","observed_orcids":["https://orcid.org/0000-0002-7470-3070"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]},{"id":"https://openalex.org/I4387153886","display_name":"University of Tampere","ror":"https://ror.org/05p6qqk79","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Vappu Rantalaiho","raw_affiliation_strings":["UNIVERSITY OF TAMPERE"],"raw_orcid":"https://orcid.org/0000-0002-7470-3070","affiliations":[{"raw_affiliation_string":"UNIVERSITY OF TAMPERE","institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5005794053"],"corresponding_institution_ids":["https://openalex.org/I166825849","https://openalex.org/I4387153886"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-rheumatoid-arthritis","display_name":"early rheumatoid arthritis","score":0.8849999904632568},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.6140000224113464},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.7279999852180481},{"id":"https://openalex.org/keywords/sulfasalazine","display_name":"sulfasalazine","score":0.9319999814033508},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.7820000052452087},{"id":"https://openalex.org/keywords/prednisolone","display_name":"prednisolone","score":0.7009999752044678},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.5569999814033508},{"id":"https://openalex.org/keywords/treatment-safety","display_name":"treatment safety","score":0.6200000047683716},{"id":"https://openalex.org/keywords/disability","display_name":"disability","score":0.4429999887943268},{"id":"https://openalex.org/keywords/treatment-guidelines","display_name":"treatment guidelines","score":0.4009999930858612},{"id":"https://openalex.org/keywords/disease-modifying-antirheumatic-drugs","display_name":"disease-modifying antirheumatic drugs","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.9289760589599609},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8579187393188477},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.5707416534423828},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5375418663024902},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49642878770828247},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.4408157467842102},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.4396994113922119},{"id":"https://openalex.org/C163276114","wikidata":"https://www.wikidata.org/wiki/Q484591","display_name":"Natural history","level":2,"score":0.4383273124694824},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:trepo.tuni.fi:10024/66907","doi":null,"is_oa":true,"landing_page_url":"https://trepo.tuni.fi/handle/10024/66907","pdf_url":"https://trepo.tuni.fi/bitstream/10024/66907/1/978-951-44-8823-8.pdf","source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"fi=V\u00e4it\u00f6skirja | en=Doctoral dissertation|"},{"id":"pmh:oai:tampub.uta.fi:10024/66907","doi":null,"is_oa":false,"landing_page_url":"http://tampub.uta.fi/handle/10024/66907","pdf_url":null,"source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"fi=V\u00e4it\u00f6skirja | en=Doctoral dissertation|"},{"id":"mag:2286328375","doi":null,"is_oa":false,"landing_page_url":"https://trepo.tuni.fi/handle/10024/66907","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:trepo.tuni.fi:10024/66907","doi":null,"is_oa":true,"landing_page_url":"https://trepo.tuni.fi/handle/10024/66907","pdf_url":"https://trepo.tuni.fi/bitstream/10024/66907/1/978-951-44-8823-8.pdf","source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"fi=V\u00e4it\u00f6skirja | en=Doctoral dissertation|"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322592","display_name":"Tampereen Yliopisto","ror":"https://ror.org/033003e23"},{"id":"https://openalex.org/F4320326518","display_name":"Tays","ror":"https://ror.org/02hvt5f17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2286328375.pdf","grobid_xml":"https://content.openalex.org/works/W2286328375.grobid-xml"},"referenced_works_count":264,"referenced_works":["https://openalex.org/W6986156","https://openalex.org/W20155150","https://openalex.org/W46650105","https://openalex.org/W48703373","https://openalex.org/W75792696","https://openalex.org/W82205316","https://openalex.org/W114781624","https://openalex.org/W564890024","https://openalex.org/W1429600871","https://openalex.org/W1485133278","https://openalex.org/W1517231282","https://openalex.org/W1550247426","https://openalex.org/W1573288623","https://openalex.org/W1646112154","https://openalex.org/W1701993624","https://openalex.org/W1770937742","https://openalex.org/W1836738882","https://openalex.org/W1848309977","https://openalex.org/W1867131794","https://openalex.org/W1904389429","https://openalex.org/W1909342577","https://openalex.org/W1914862478","https://openalex.org/W1939689836","https://openalex.org/W1953534612","https://openalex.org/W1955601105","https://openalex.org/W1962112167","https://openalex.org/W1966438794","https://openalex.org/W1967020676","https://openalex.org/W1967672301","https://openalex.org/W1973746261","https://openalex.org/W1974551082","https://openalex.org/W1974802441","https://openalex.org/W1976068756","https://openalex.org/W1979385321","https://openalex.org/W1982145358","https://openalex.org/W1982272985","https://openalex.org/W1982348705","https://openalex.org/W1983134858","https://openalex.org/W1983510723","https://openalex.org/W1985004174","https://openalex.org/W1985338929","https://openalex.org/W1985763670","https://openalex.org/W1985822447","https://openalex.org/W1987074162","https://openalex.org/W1987453516","https://openalex.org/W1989162705","https://openalex.org/W1989773663","https://openalex.org/W1991687557","https://openalex.org/W1994865061","https://openalex.org/W1996075673","https://openalex.org/W1996389186","https://openalex.org/W1997568521","https://openalex.org/W1997888027","https://openalex.org/W1999777294","https://openalex.org/W2000333164","https://openalex.org/W2000905503","https://openalex.org/W2007722006","https://openalex.org/W2008964053","https://openalex.org/W2010667387","https://openalex.org/W2012620405","https://openalex.org/W2012960794","https://openalex.org/W2013382580","https://openalex.org/W2013555856","https://openalex.org/W2014804217","https://openalex.org/W2015515502","https://openalex.org/W2017473710","https://openalex.org/W2019114331","https://openalex.org/W2021832018","https://openalex.org/W2023768752","https://openalex.org/W2024659694","https://openalex.org/W2024760078","https://openalex.org/W2025314662","https://openalex.org/W2025408360","https://openalex.org/W2031518811","https://openalex.org/W2031838098","https://openalex.org/W2031988556","https://openalex.org/W2032140498","https://openalex.org/W2033299724","https://openalex.org/W2033503255","https://openalex.org/W2035503887","https://openalex.org/W2037874703","https://openalex.org/W2039077567","https://openalex.org/W2041781448","https://openalex.org/W2041803731","https://openalex.org/W2042620780","https://openalex.org/W2043180847","https://openalex.org/W2044601575","https://openalex.org/W2046540088","https://openalex.org/W2046628605","https://openalex.org/W2046967539","https://openalex.org/W2051728683","https://openalex.org/W2052047947","https://openalex.org/W2053272500","https://openalex.org/W2054060503","https://openalex.org/W2055660220","https://openalex.org/W2056789161","https://openalex.org/W2056999436","https://openalex.org/W2057215073","https://openalex.org/W2058498324","https://openalex.org/W2060793909","https://openalex.org/W2063217417","https://openalex.org/W2065104971","https://openalex.org/W2067257696","https://openalex.org/W2067437944","https://openalex.org/W2069959649","https://openalex.org/W2070543794","https://openalex.org/W2071054988","https://openalex.org/W2073578075","https://openalex.org/W2074604845","https://openalex.org/W2078317963","https://openalex.org/W2079359234","https://openalex.org/W2080638211","https://openalex.org/W2081476654","https://openalex.org/W2083525176","https://openalex.org/W2087410926","https://openalex.org/W2091732273","https://openalex.org/W2092063686","https://openalex.org/W2094633788","https://openalex.org/W2095146056","https://openalex.org/W2098539717","https://openalex.org/W2098889063","https://openalex.org/W2098919737","https://openalex.org/W2099334955","https://openalex.org/W2099885994","https://openalex.org/W2100260684","https://openalex.org/W2101830854","https://openalex.org/W2103148720","https://openalex.org/W2104208528","https://openalex.org/W2106806370","https://openalex.org/W2107199822","https://openalex.org/W2109237866","https://openalex.org/W2109445459","https://openalex.org/W2110177517","https://openalex.org/W2111153776","https://openalex.org/W2111540856","https://openalex.org/W2112753620","https://openalex.org/W2113228021","https://openalex.org/W2113430293","https://openalex.org/W2113630516","https://openalex.org/W2114583929","https://openalex.org/W2115004354","https://openalex.org/W2115068422","https://openalex.org/W2115608334","https://openalex.org/W2117738981","https://openalex.org/W2118704147","https://openalex.org/W2120332428","https://openalex.org/W2120441278","https://openalex.org/W2121311666","https://openalex.org/W2122000071","https://openalex.org/W2122416803","https://openalex.org/W2123127083","https://openalex.org/W2123298874","https://openalex.org/W2125121941","https://openalex.org/W2126113140","https://openalex.org/W2126275861","https://openalex.org/W2126429231","https://openalex.org/W2126952749","https://openalex.org/W2127535091","https://openalex.org/W2128952811","https://openalex.org/W2129486471","https://openalex.org/W2130631271","https://openalex.org/W2131913726","https://openalex.org/W2132031538","https://openalex.org/W2133744666","https://openalex.org/W2133782842","https://openalex.org/W2134171514","https://openalex.org/W2135011878","https://openalex.org/W2135644975","https://openalex.org/W2135763952","https://openalex.org/W2135843902","https://openalex.org/W2136042500","https://openalex.org/W2136184915","https://openalex.org/W2138742783","https://openalex.org/W2138959263","https://openalex.org/W2139063743","https://openalex.org/W2140235327","https://openalex.org/W2141959872","https://openalex.org/W2142232425","https://openalex.org/W2142279201","https://openalex.org/W2143218813","https://openalex.org/W2144819232","https://openalex.org/W2145439729","https://openalex.org/W2146002757","https://openalex.org/W2146166312","https://openalex.org/W2146502982","https://openalex.org/W2146831240","https://openalex.org/W2147623386","https://openalex.org/W2147787332","https://openalex.org/W2148053400","https://openalex.org/W2148311007","https://openalex.org/W2149564172","https://openalex.org/W2151337536","https://openalex.org/W2151366126","https://openalex.org/W2151476793","https://openalex.org/W2152348310","https://openalex.org/W2153049551","https://openalex.org/W2153236635","https://openalex.org/W2153405936","https://openalex.org/W2153461196","https://openalex.org/W2153732725","https://openalex.org/W2154341553","https://openalex.org/W2155109530","https://openalex.org/W2155865143","https://openalex.org/W2156665585","https://openalex.org/W2156996668","https://openalex.org/W2158058290","https://openalex.org/W2158590685","https://openalex.org/W2158733279","https://openalex.org/W2160494647","https://openalex.org/W2161757042","https://openalex.org/W2162002325","https://openalex.org/W2162260707","https://openalex.org/W2162351377","https://openalex.org/W2162522385","https://openalex.org/W2163487393","https://openalex.org/W2163817180","https://openalex.org/W2164081230","https://openalex.org/W2165584277","https://openalex.org/W2165631659","https://openalex.org/W2166732840","https://openalex.org/W2166771071","https://openalex.org/W2167550860","https://openalex.org/W2168148602","https://openalex.org/W2168429696","https://openalex.org/W2169080396","https://openalex.org/W2169655406","https://openalex.org/W2170013081","https://openalex.org/W2170102479","https://openalex.org/W2170525451","https://openalex.org/W2170668311","https://openalex.org/W2170873039","https://openalex.org/W2171327215","https://openalex.org/W2171880913","https://openalex.org/W2172011800","https://openalex.org/W2206746226","https://openalex.org/W2217934711","https://openalex.org/W2268787646","https://openalex.org/W2291852233","https://openalex.org/W2314052274","https://openalex.org/W2320562573","https://openalex.org/W2338984036","https://openalex.org/W2340084730","https://openalex.org/W2340862092","https://openalex.org/W2345361184","https://openalex.org/W2400970675","https://openalex.org/W2402170083","https://openalex.org/W2408791573","https://openalex.org/W2409808456","https://openalex.org/W2410239398","https://openalex.org/W2411570043","https://openalex.org/W2411832526","https://openalex.org/W2412662820","https://openalex.org/W2413468471","https://openalex.org/W2413628343","https://openalex.org/W2416195612","https://openalex.org/W2417509515","https://openalex.org/W2417907140","https://openalex.org/W2465275442","https://openalex.org/W2465986126","https://openalex.org/W2466573681","https://openalex.org/W2467033040","https://openalex.org/W2468464143","https://openalex.org/W2607079988","https://openalex.org/W4308769923"],"related_works":["https://openalex.org/W163304964","https://openalex.org/W7133156477","https://openalex.org/W2241661558","https://openalex.org/W2411077310","https://openalex.org/W6983756589","https://openalex.org/W7052429370","https://openalex.org/W59306933","https://openalex.org/W7004843848","https://openalex.org/W2114990760","https://openalex.org/W2321940495"],"abstract_inverted_index":{"Nivelreuman":[0],"luonnollinen":[1],"kulku":[2],"johtaa":[3],"tulehduksen":[4],"kautta":[5],"nivelten":[6],"tuhoutumiseen,":[7],"toiminta-":[8],"ja":[9,12,26,33,59,68,79,95,118,125,305,357,374],"ty\u00f6kyvyn":[10],"alenemiseen":[11],"lis\u00e4\u00e4ntyneeseen":[13],"kuolleisuuteen.":[14],"Viime":[15],"vuosikymmenin\u00e4":[16],"reumal\u00e4\u00e4kkeiden":[17],"on":[18,194,213,272,282,369,387,400],"todettu":[19],"est\u00e4v\u00e4n,":[20],"tai":[21,122],"ainakin":[22],"hidastavan":[23],"t\u00e4t\u00e4":[24],"taudinkulkua,":[25],"niinp\u00e4":[27],"nyky\u00e4\u00e4n":[28],"maailmanlaajuisesti":[29],"nivelreumaan":[30,230],"suositellaan":[31,65],"varhaista":[32,109],"aggressiivista":[34],"hoitoa,":[35],"joskin":[36,184],"hoitosuositukset":[37],"eri":[38],"maissa":[39],"eroavat":[40],"jonkin":[41],"verran":[42],"toisistaan.":[43],"Suomessa,":[44],"suurelta":[45],"osin":[46],"kansallisen":[47],"monikeskustutkimuksen,":[48],"FIN-REKO:n":[49],"(Finnish":[50],"Rheumatoid":[51],"Arthritis":[52],"Combination":[53],"Therapy":[54],"Trial,":[55],"FIN-RACo)":[56],"suotuisten":[57],"2-":[58],"5-vuotistulosten":[60],"ansiosta,":[61],"aktiivisen":[62],"nivelreuman":[63,203,322,385],"aloitushoidoksi":[64],"kolmen":[66,116,295,364],"reumal\u00e4\u00e4kkeen":[67,117,299],"pieniannoksisen":[69],"kortisonin":[70,119],"yhdistelm\u00e4hoitoa.":[71],"Nykyisess\u00e4":[72],"tutkimuksessa":[73],"halusimme":[74],"tutkia":[75],"t\u00e4m\u00e4n":[76],"hoidon":[77],"pitk\u00e4aikaisvaikutuksia":[78],"turvallisuutta":[80],"analysoimalla":[81],"FIN-REKO-tutkimuksen":[82],"11":[83],"vuoden":[84,138,248,256,319],"seurantatulokset.":[85],"Lis\u00e4ksi":[86,172],"pyrimme":[87],"kartoittamaan":[88],"kuinka":[89],"reumal\u00e4\u00e4kkeit\u00e4":[90],"Suomessa":[91,227,271,388],"k\u00e4ytet\u00e4\u00e4n":[92],"varhaisessa":[93],"nivelreumassa,":[94],"onko":[96],"mahdollisesti":[97],"aikaisempaa":[98],"aktiivisemmilla":[99],"hoitok\u00e4yt\u00e4nn\u00f6ill\u00e4":[100],"voitu":[101,343],"v\u00e4hent\u00e4\u00e4":[102],"pysyv\u00e4\u00e4":[103],"ty\u00f6kyvytt\u00f6myytt\u00e4.\\n\\nVuonna":[104],"1993":[105],"alkaneessa":[106],"FIN-REKO-tutkimuksessa":[107],"199":[108],"nivelreumaa":[110,275],"sairastavaa":[111],"potilasta":[112,147],"satunnaistettiin":[113],"saamaan":[114],"joko":[115],"yhdistelm\u00e4hoitoa":[120,366],"(FIN-RACo-ryhm\u00e4)":[121],"yksitt\u00e4ist\u00e4":[123],"reumal\u00e4\u00e4kett\u00e4":[124,308],"tarvittaessa":[126],"kortisonia":[127],"(SINGLE-ryhm\u00e4).":[128],"Hoito":[129],"molemmissa":[130,152],"ryhmiss\u00e4":[131,153],"t\u00e4ht\u00e4si":[132],"t\u00e4yteen":[133],"oireettomuuteen":[134],"eli":[135],"remissioon.":[136],"Kahden":[137],"j\u00e4lkeen":[139],"hoidot":[140],"olivat":[141,164,188,347],"vapaat.":[142],"Yhteentoista":[143],"vuoteen":[144],"asti":[145],"138":[146],"jatkoi":[148],"seurannassa.":[149],"Toimintakyky":[150],"oli":[151,179,309,317],"s\u00e4ilynyt":[154],"hyv\u00e4n\u00e4,":[155],"puolella":[156],"potilaista":[157,292,316],"ei":[158,339],"ollut":[159],"siin\u00e4":[160],"mink\u00e4\u00e4nlaista":[161],"rajoitusta.":[162],"Remissiot":[163],"kuitenkin":[165,214],"yleisempi\u00e4":[166],"FIN-RACo-ryhm\u00e4ss\u00e4":[167,181],"(37%)":[168],"kuin":[169,182,190,206,217,378],"SINGLE-ryhm\u00e4ss\u00e4":[170],"(19%).":[171],"pysyvi\u00e4":[173],"vaurioita":[174],"osoittavia,":[175],"r\u00f6ntgenkuvissa":[176],"n\u00e4kyvi\u00e4":[177],"muutoksia":[178],"v\u00e4hemm\u00e4n":[180,375],"SINGLE-ryhm\u00e4ss\u00e4,":[183],"molempien":[185],"ryhmien":[186],"r\u00f6ntgenl\u00f6yd\u00f6kset":[187],"v\u00e4h\u00e4isempi\u00e4":[189],"useissa":[191],"aikaisemmissa":[192],"tutkimuksissa":[193],"todettu.":[195],"Remissioon":[196],"t\u00e4ht\u00e4\u00e4v\u00e4":[197],"hoito":[198,281,386],"hillitsee":[199],"siis":[200],"pitk\u00e4ll\u00e4kin":[201],"t\u00e4ht\u00e4imell\u00e4":[202],"etenemist\u00e4":[204,377],"paremmin":[205],"vanhanaikainen,":[207],"konservatiivisempi":[208],"hoito.":[209],"Yhdistelm\u00e4l\u00e4\u00e4kityksell\u00e4":[210],"toteutettuna":[211],"se":[212],"viel\u00e4":[215,370],"tehokkaampaa":[216],"yhdell\u00e4":[218],"reumal\u00e4\u00e4kkeell\u00e4.\\n\\nTutkimuksen":[219],"toisessa":[220],"osassa":[221,262],"ker\u00e4ttiin":[222],"Kansanel\u00e4kelaitoksen":[223],"(Kela)":[224],"rekisteritiedoista":[225],"kaikki":[226],"vuosina":[228],"2000-2007":[229],"sairastuneet":[231],"14":[232],"878":[233],"potilasta,":[234],"joiden":[235],"tiedot":[236],"analysoitiin":[237],"kaksivuotiskohorteittain":[238],"(2000-01,":[239],"2002-03,":[240],"2004-05,":[241],"2006-07).":[242],"Erityisesti":[243],"mielenkiinto":[244],"kohdistui":[245],"potilaiden":[246],"ensimm\u00e4isen":[247,294],"aikana":[249,297,321],"ostamiin":[250],"reumal\u00e4\u00e4kkeisiin":[251],"sek\u00e4":[252],"toisaalta":[253],"ty\u00f6kyvytt\u00f6myyden":[254,398],"ilmaantuvuuteen":[255],"2008":[257],"loppuun":[258],"menness\u00e4.":[259],"T\u00e4ss\u00e4":[260],"tutkimuksen":[261],"todettiin,":[263],"ett\u00e4":[264,287,349],"useista":[265],"muista":[266],"maista":[267],"raportoituun":[268],"tilanteeseen":[269],"verrattuna":[270],"hoidettu":[273],"tuoretta":[274],"aktiivisesti":[276],"jo":[277],"tutkimusjakson":[278,288],"alussa,":[279],"mutta":[280,330],"k\u00e4ynyt":[283],"jatkuvasti":[284],"aktiivisemmaksi":[285],"niin,":[286],"lopulla":[289],"yli":[290],"puolelle":[291],"aloitettiin":[293],"kuukauden":[296],"usean":[298],"yhdistelm\u00e4hoito,":[300],"metotreksaattia":[301],"sai":[302],"l\u00e4hes":[303],"70%,":[304],"ilman":[306],"mit\u00e4\u00e4n":[307],"vain":[310,333],"alle":[311],"5%":[312],"potilaista.":[313],"Diagnoosihetkell\u00e4":[314],"ty\u00f6kykyisist\u00e4":[315],"kahden":[318],"seurannan":[320],"vuoksi":[323],"ty\u00f6kyvytt\u00f6myysel\u00e4kkeelle":[324],"j\u00e4\u00e4nyt":[325],"ensimm\u00e4isest\u00e4":[326],"vuosikohortista":[327],"(2000-01)":[328],"8.9%,":[329],"viimeisest\u00e4":[331],"(2006-07)":[332],"4.8%.":[334],"Ty\u00f6kyvytt\u00f6myyden":[335],"v\u00e4henemist\u00e4":[336],"selitt\u00e4vi\u00e4":[337],"tekij\u00f6it\u00e4":[338],"t\u00e4st\u00e4":[340],"tutkimusaineistossa":[341],"valitettavasti":[342],"analysoida.":[344],"V\u00e4it\u00f6skirjan":[345],"p\u00e4\u00e4l\u00f6yd\u00f6kset":[346],"siis,":[348],"aktiivinen,":[350],"remissioon":[351],"pyrkiv\u00e4":[352],"hoitostrategia":[353],"tuottaa":[354],"hyv\u00e4n":[355],"kliinisen":[356],"radiologisen":[358],"tuloksen":[359],"useimmilla":[360],"potilailla.":[361],"Kuitenkin":[362],"alkuvaiheessa":[363,379],"l\u00e4\u00e4kkeen":[365],"saaneilla":[367],"potilailla":[368],"pitk\u00e4aikaisseurannassakin":[371],"enemm\u00e4n":[372],"remissioita":[373],"radiologista":[376],"yksitt\u00e4ishoitoa":[380],"saaneilla.":[381],"T\u00e4ll\u00e4":[382],"vuosituhannella":[383],"varhaisen":[384],"muuttunut":[389],"entist\u00e4kin":[390],"aktiivisemmaksi.":[391],"Samaan":[392],"aikaan":[393],"varhaisesta":[394],"nivelreumasta":[395],"johtuvan":[396],"pitk\u00e4aikaisen":[397],"ilmaantuvuus":[399],"alentunut.":[401]},"counts_by_year":[{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}