{"id":"https://openalex.org/W2284777302","doi":null,"title":"Silicon, iron and titanium doped calcium phosphate-based glass reinforced biodegradable polyester composites as bone analogous materials","display_name":"Silicon, iron and titanium doped calcium phosphate-based glass reinforced biodegradable polyester composites as bone analogous materials","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2284777302","mag":"2284777302"},"language":"en","primary_location":{"id":"mag:2284777302","doi":null,"is_oa":false,"landing_page_url":"http://ui.adsabs.harvard.edu/abs/2012PhDT.......426S/abstract","pdf_url":null,"source":{"id":"https://openalex.org/S4306522422","display_name":"PhDT","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PhDT","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084658636","display_name":"Maziar Shah Mohammadi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Maziar Shah Mohammadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5084658636"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10544","display_name":"Glass properties and applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2503","display_name":"Ceramics and Composites"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phosphate-glass","display_name":"phosphate glass","score":0.8130000233650208},{"id":"https://openalex.org/keywords/calcium-phosphate-glass","display_name":"calcium phosphate glass","score":0.734000027179718},{"id":"https://openalex.org/keywords/silicon-doping","display_name":"silicon doping","score":0.6190000176429749},{"id":"https://openalex.org/keywords/fe-doping","display_name":"iron doping","score":0.9909999966621399},{"id":"https://openalex.org/keywords/titanium-doping","display_name":"titanium doping","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bone-tissue-engineering","display_name":"bone tissue engineering","score":0.6359999775886536},{"id":"https://openalex.org/keywords/bone-scaffolds","display_name":"bone scaffolds","score":0.7350000143051147},{"id":"https://openalex.org/keywords/polycaprolactone","display_name":"polycaprolactone","score":0.9039999842643738},{"id":"https://openalex.org/keywords/polylactic-acid","display_name":"polylactic acid","score":0.9319999814033508},{"id":"https://openalex.org/keywords/poly-d-l-lactide","display_name":"poly(D,L-lactide)","score":0.6520000100135803},{"id":"https://openalex.org/keywords/glass-fibre","display_name":"glass fibre","score":0.625},{"id":"https://openalex.org/keywords/ion-release","display_name":"ion release","score":0.8420000076293945},{"id":"https://openalex.org/keywords/alkaline-phosphatase-activity","display_name":"alkaline phosphatase activity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/mc3t3-e1-cells","display_name":"MC3T3-E1 cells","score":0.9449999928474426},{"id":"https://openalex.org/keywords/mechanical-properties","display_name":"mechanical properties","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C119394753","wikidata":"https://www.wikidata.org/wiki/Q188245","display_name":"Polyester","level":2,"score":0.6450939178466797},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6390326023101807},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.569520890712738},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.5310825705528259},{"id":"https://openalex.org/C2781094431","wikidata":"https://www.wikidata.org/wiki/Q7187431","display_name":"Phosphate glass","level":3,"score":0.5143747925758362},{"id":"https://openalex.org/C506065880","wikidata":"https://www.wikidata.org/wiki/Q716","display_name":"Titanium","level":2,"score":0.462709903717041},{"id":"https://openalex.org/C57863236","wikidata":"https://www.wikidata.org/wiki/Q1130571","display_name":"Doping","level":2,"score":0.41377994418144226},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.40648552775382996},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24478378891944885},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.19150760769844055},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.09932327270507812},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2284777302","doi":null,"is_oa":false,"landing_page_url":"http://ui.adsabs.harvard.edu/abs/2012PhDT.......426S/abstract","pdf_url":null,"source":{"id":"https://openalex.org/S4306522422","display_name":"PhDT","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PhDT","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":187,"referenced_works":["https://openalex.org/W40301670","https://openalex.org/W55955895","https://openalex.org/W66638518","https://openalex.org/W78392257","https://openalex.org/W123543948","https://openalex.org/W159333316","https://openalex.org/W649072342","https://openalex.org/W652795422","https://openalex.org/W751670884","https://openalex.org/W1503363495","https://openalex.org/W1536028936","https://openalex.org/W1536407374","https://openalex.org/W1558866275","https://openalex.org/W1607413909","https://openalex.org/W1689347801","https://openalex.org/W1914416900","https://openalex.org/W1929827371","https://openalex.org/W1964622801","https://openalex.org/W1964818747","https://openalex.org/W1966492729","https://openalex.org/W1966947589","https://openalex.org/W1969289988","https://openalex.org/W1969334819","https://openalex.org/W1969735045","https://openalex.org/W1970280620","https://openalex.org/W1971339046","https://openalex.org/W1973067831","https://openalex.org/W1973229108","https://openalex.org/W1973264174","https://openalex.org/W1974541015","https://openalex.org/W1974862551","https://openalex.org/W1975258497","https://openalex.org/W1976415200","https://openalex.org/W1976991816","https://openalex.org/W1977217152","https://openalex.org/W1977534266","https://openalex.org/W1978162577","https://openalex.org/W1979467412","https://openalex.org/W1979837737","https://openalex.org/W1984671834","https://openalex.org/W1986070515","https://openalex.org/W1986485290","https://openalex.org/W1987482585","https://openalex.org/W1987829320","https://openalex.org/W1988804877","https://openalex.org/W1989653618","https://openalex.org/W1990387724","https://openalex.org/W1993470613","https://openalex.org/W1994381312","https://openalex.org/W1995434070","https://openalex.org/W1996552900","https://openalex.org/W1996709540","https://openalex.org/W1999096092","https://openalex.org/W1999684723","https://openalex.org/W2000833954","https://openalex.org/W2002914571","https://openalex.org/W2003252624","https://openalex.org/W2003527940","https://openalex.org/W2007451128","https://openalex.org/W2007787821","https://openalex.org/W2009070599","https://openalex.org/W2009793668","https://openalex.org/W2010940871","https://openalex.org/W2013453106","https://openalex.org/W2014068204","https://openalex.org/W2014785305","https://openalex.org/W2015209658","https://openalex.org/W2015593531","https://openalex.org/W2016256795","https://openalex.org/W2017366846","https://openalex.org/W2017916593","https://openalex.org/W2018543522","https://openalex.org/W2019988730","https://openalex.org/W2022022644","https://openalex.org/W2022076816","https://openalex.org/W2023392547","https://openalex.org/W2024455489","https://openalex.org/W2027338314","https://openalex.org/W2029781839","https://openalex.org/W2029969442","https://openalex.org/W2032032896","https://openalex.org/W2032618902","https://openalex.org/W2032757918","https://openalex.org/W2033418840","https://openalex.org/W2034737207","https://openalex.org/W2037349387","https://openalex.org/W2037461551","https://openalex.org/W2037542296","https://openalex.org/W2037965840","https://openalex.org/W2038659352","https://openalex.org/W2038929699","https://openalex.org/W2040754748","https://openalex.org/W2041558541","https://openalex.org/W2042270475","https://openalex.org/W2043310171","https://openalex.org/W2045962685","https://openalex.org/W2046071992","https://openalex.org/W2047919271","https://openalex.org/W2049283367","https://openalex.org/W2049722249","https://openalex.org/W2049847899","https://openalex.org/W2057937678","https://openalex.org/W2059420231","https://openalex.org/W2062049927","https://openalex.org/W2063751349","https://openalex.org/W2064241693","https://openalex.org/W2064403993","https://openalex.org/W2066348702","https://openalex.org/W2067026131","https://openalex.org/W2069095874","https://openalex.org/W2071909378","https://openalex.org/W2072429116","https://openalex.org/W2072825812","https://openalex.org/W2072889298","https://openalex.org/W2073813406","https://openalex.org/W2073945993","https://openalex.org/W2076098150","https://openalex.org/W2076249607","https://openalex.org/W2078126231","https://openalex.org/W2079104480","https://openalex.org/W2079979110","https://openalex.org/W2081425199","https://openalex.org/W2081828383","https://openalex.org/W2083265178","https://openalex.org/W2083581261","https://openalex.org/W2084304606","https://openalex.org/W2085303635","https://openalex.org/W2086238635","https://openalex.org/W2087635529","https://openalex.org/W2087987629","https://openalex.org/W2088697330","https://openalex.org/W2089960469","https://openalex.org/W2090004724","https://openalex.org/W2090232626","https://openalex.org/W2090263279","https://openalex.org/W2091921033","https://openalex.org/W2092881292","https://openalex.org/W2093457729","https://openalex.org/W2093998120","https://openalex.org/W2096412230","https://openalex.org/W2100627342","https://openalex.org/W2103745164","https://openalex.org/W2104427836","https://openalex.org/W2105278093","https://openalex.org/W2106035984","https://openalex.org/W2106781115","https://openalex.org/W2111415695","https://openalex.org/W2112880618","https://openalex.org/W2113042424","https://openalex.org/W2114965343","https://openalex.org/W2118877693","https://openalex.org/W2118948459","https://openalex.org/W2119712762","https://openalex.org/W2121976442","https://openalex.org/W2122996284","https://openalex.org/W2124195334","https://openalex.org/W2125197189","https://openalex.org/W2127819121","https://openalex.org/W2130971715","https://openalex.org/W2131983765","https://openalex.org/W2132309525","https://openalex.org/W2140251955","https://openalex.org/W2142720627","https://openalex.org/W2143882111","https://openalex.org/W2148727448","https://openalex.org/W2152953685","https://openalex.org/W2153425158","https://openalex.org/W2155124369","https://openalex.org/W2158572699","https://openalex.org/W2161762920","https://openalex.org/W2164166548","https://openalex.org/W2165221289","https://openalex.org/W2166118779","https://openalex.org/W2166149223","https://openalex.org/W2169528392","https://openalex.org/W2171800994","https://openalex.org/W2172021353","https://openalex.org/W2224239138","https://openalex.org/W2312898741","https://openalex.org/W2383509278","https://openalex.org/W2488269141","https://openalex.org/W2489037557","https://openalex.org/W2490027581","https://openalex.org/W2498350993","https://openalex.org/W2501384800","https://openalex.org/W2503937731","https://openalex.org/W2524883113"],"related_works":["https://openalex.org/W2045730784","https://openalex.org/W2886871738","https://openalex.org/W2009070599","https://openalex.org/W1996350487","https://openalex.org/W2059970115","https://openalex.org/W1977534266","https://openalex.org/W66638203","https://openalex.org/W2203869072","https://openalex.org/W2044503569","https://openalex.org/W2118525276"],"abstract_inverted_index":{"Bone":[0],"defects":[1],"resulting":[2,303],"from":[3,210],"disease":[4],"or":[5,180,236],"traumatic":[6],"injury":[7],"is":[8],"a":[9,30,118,287,305,388],"major":[10],"health":[11],"care":[12],"problem":[13],"worldwide.":[14],"Tissue":[15],"engineering":[16,417],"offers":[17],"an":[18,41],"alternative":[19],"approach":[20],"to":[21,49,159,214,297,339,359,430],"repair":[22],"and":[23,45,72,83,96,126,136,139,148,154,172,187,191,226,244,246,251,268,276,292,329,379,438],"regenerate":[24],"bone":[25,94,259,415],"through":[26,74],"the":[27,51,81,108,197,202,207,211,254,271,280,293,298,312,316,333,347,371,374,400],"use":[28],"of":[29,85,112,199,219,256,279,300,315,354,373,406,421,440],"cell-scaffold":[31],"construct.":[32],"The":[33,419],"scaffold":[34],"should":[35,46],"be":[36,47,58,70],"biodegradable,":[37],"biocompatible,":[38],"porous":[39],"with":[40,123,178,253,320,357,383,395,426],"open":[42,422],"pore":[43,391,401],"structure,":[44],"able":[48],"withstand":[50],"applied":[52],"forces.":[53],"Phosphate-based":[54],"glasses":[55],"(PGs)":[56],"may":[57],"used":[59],"as":[60,166,168,230,233],"reinforcing":[61],"agents":[62],"in":[63,93,183,201,304,368,390,409],"degradable":[64,258],"composites":[65,326,356,375],"since":[66],"their":[67,75,340],"degradation":[68],"can":[69],"predicted":[71],"controlled":[73],"chemistry.":[76],"This":[77,98],"doctoral":[78],"dissertation":[79],"describes":[80],"development":[82],"evaluation":[84],"PGs":[86,229],"reinforced":[87],"biodegradable":[88,240],"polyesters":[89,241],"for":[90,414],"intended":[91],"applications":[92],"augmentation":[95],"regeneration.":[97],"research":[99],"was":[100,194,263,283,335,393],"divided":[101],"into":[102,239],"three":[103],"main":[104],"objectives:":[105],"1)":[106],"Investigating":[107,346],"composition":[109,267],"dependent":[110],"properties":[111,278,314],"novel":[113],"PG":[114,212,266],"formulations":[115,151,204],"by":[116],"doping":[117,177],"sodium-free":[119],"calcium":[120],"phosphate-based":[121],"glass":[122],"SiO2,":[124],"Fe2O3,":[125],"TiO2.":[127],"Accordingly,":[128],"(50P2O5-40CaO-":[129],"xSiO2-(10-x)Fe2O3,":[130],"where":[131,141],"x":[132,142],"=":[133,143],"10,":[134,144],"5":[135],"0":[137,149],"mol.%)":[138,150],"(50P2O5-40CaO-xSiO2-(10-x)TiO2":[140],"7,":[145],"5,":[146],"3":[147],"were":[152,327],"developed":[153],"characterised.":[155],"SiO2":[156,200],"incorporation":[157],"led":[158,296],"increased":[160,424],"solubility,":[161],"ion":[162],"release,":[163,275],"pH":[164],"reduction,":[165],"well":[167],"hydrophilicity,":[169],"surface":[170,173],"energy,":[171],"polarity.":[174],"In":[175,386],"contrast,":[176],"Fe2O3":[179],"TiO2":[181],"resulted":[182,367],"more":[184],"durable":[185],"glasses,":[186],"improved":[188],"cell":[189,330],"attachment":[190],"viability.":[192],"It":[193,262,282],"hypothesised":[195,285],"that":[196,265,286,324],"presence":[198],"TiO2-doped":[203],"could":[205],"up-regulate":[206],"ionic":[208,274,342],"release":[209,343],"leading":[213],"higher":[215],"alkaline":[216],"phosphatase":[217],"activity":[218],"MC3T3-E1":[220,321],"cells.":[221],"2)":[222],"Incorporating":[223],"Si,":[224],"Fe,":[225],"Ti":[227],"doped":[228],"fillers,":[231],"either":[232],"particulates":[234],"(PGPs)":[235],"fibres":[237],"(PGFs),":[238],"(polycaprolactone":[242],"(PCL)":[243],"semi-crystalline":[245],"amorphous":[247],"poly(lactic":[248],"acid)":[249],"(PLA":[250],"PDLLA))":[252],"aim":[255],"developing":[257],"analogous":[260],"composites.":[261,281,317],"found":[264],"geometry":[269],"dictated":[270],"weight":[272,308],"loss,":[273],"mechanical":[277,313],"also":[284],"potential":[288],"reaction":[289],"between":[290,377],"Si":[291],"ester":[294],"bond":[295],"formation":[299],"carboxylate":[301],"by-products":[302],"lower":[306],"molecular":[307],"polymer,":[309],"thus":[310],"affecting":[311],"Cytocompatibility":[318],"assessment":[319],"preosteoblasts":[322],"showed":[323],"these":[325],"cytocompatible,":[328],"alignment":[331],"along":[332],"PGFs":[334],"observed":[336,394],"possibly":[337],"due":[338],"favourable":[341],"properties.":[344],"3)":[345],"solid-state":[348],"foaming":[349],"using":[350],"carbon":[351],"dioxide":[352],"(CO2)":[353],"PDLLA-PGP":[355,441],"up":[358],"30":[360,433],"vol.%":[361,434],"filler":[362],"content.":[363,385],"While":[364],"PDLLA":[365],"foams":[366],"92%":[369],"porosity,":[370],"porosity":[372],"ranged":[376],"79":[378],"91%":[380],"which":[381],"decreased":[382],"PGP":[384,397,427],"addition,":[387],"reduction":[389],"size":[392,402],"increasing":[396],"content;":[398],"however,":[399],"maintained":[403],"its":[404],"range":[405],"200-500":[407],"\u00b5m":[408],"all":[410],"composite":[411],"foams,":[412],"suitable":[413],"tissue":[416],"applications.":[418],"percentage":[420],"pores":[423],"significantly":[425],"content":[428],"(up":[429],"78%":[431],"at":[432],"PGP).":[435],"Compressive":[436],"strength":[437],"modulus":[439],"foams\u2026":[442]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
