{"id":"https://openalex.org/W2281925648","doi":"https://doi.org/","title":"Structural changes in pre-eclamptic and eclamptic placentas--an ultrastructural study.","display_name":"Structural changes in pre-eclamptic and eclamptic placentas--an ultrastructural study.","publication_year":2011,"publication_date":"2011-08-01","ids":{"openalex":"https://openalex.org/W2281925648","doi":"https://doi.org/","mag":"2281925648","pmid":"https://pubmed.ncbi.nlm.nih.gov/21798135"},"language":"en","primary_location":{"id":"pmid:21798135","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21798135","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the College of Physicians and Surgeons--Pakistan : JCPSP","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110316059","display_name":"Sujatha Salgado","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142651801","display_name":"University of Kelaniya","ror":"https://ror.org/02r91my29","country_code":"LK","type":"education","lineage":["https://openalex.org/I142651801"]}],"countries":["LK"],"is_corresponding":false,"raw_author_name":"Sujatha S Salgado","raw_affiliation_strings":["Department of Anatomy, Faculty of Medicine, University of Kelaniya, Sri Lanka. sujeesal@yahoo.com","Department of Anatomy, Faculty of Medicine, University of Kelaniya, Sri Lanka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomy, Faculty of Medicine, University of Kelaniya, Sri Lanka. sujeesal@yahoo.com","institution_ids":["https://openalex.org/I142651801"]},{"raw_affiliation_string":"Department of Anatomy, Faculty of Medicine, University of Kelaniya, Sri Lanka","institution_ids":["https://openalex.org/I142651801"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055567766","display_name":"M K R Salgado","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M K R Salgado","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7881,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.78400416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"21","issue":"8","first_page":"482","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/eclampsia","display_name":"eclampsia","score":1.0},{"id":"https://openalex.org/keywords/placental-ultrastructure","display_name":"placental ultrastructure","score":0.9419999718666077},{"id":"https://openalex.org/keywords/chorionic-villi","display_name":"chorionic villi","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cytotrophoblast","display_name":"cytotrophoblast","score":0.8610000014305115},{"id":"https://openalex.org/keywords/syncytiotrophoblast","display_name":"syncytiotrophoblast","score":0.890999972820282},{"id":"https://openalex.org/keywords/mitochondrial-vacuolation","display_name":"mitochondrial vacuolation","score":0.7170000076293945},{"id":"https://openalex.org/keywords/placental-insufficiency","display_name":"placental insufficiency","score":0.5669999718666077},{"id":"https://openalex.org/keywords/hypertensive-disorders-of-pregnancy","display_name":"hypertensive disorders of pregnancy","score":0.6940000057220459}],"concepts":[{"id":"https://openalex.org/C2777605040","wikidata":"https://www.wikidata.org/wiki/Q3009555","display_name":"Cytotrophoblast","level":5,"score":0.8890576362609863},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.7600629329681396},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.740365743637085},{"id":"https://openalex.org/C2781385326","wikidata":"https://www.wikidata.org/wiki/Q2272222","display_name":"Chorionic villi","level":5,"score":0.7102375030517578},{"id":"https://openalex.org/C2781276381","wikidata":"https://www.wikidata.org/wiki/Q552348","display_name":"Eclampsia","level":3,"score":0.6997988224029541},{"id":"https://openalex.org/C2779315647","wikidata":"https://www.wikidata.org/wiki/Q2745412","display_name":"Syncytiotrophoblast","level":5,"score":0.5980226993560791},{"id":"https://openalex.org/C40479148","wikidata":"https://www.wikidata.org/wiki/Q844460","display_name":"Syncytium","level":3,"score":0.5457479357719421},{"id":"https://openalex.org/C2776193487","wikidata":"https://www.wikidata.org/wiki/Q32846","display_name":"Basement membrane","level":2,"score":0.5396705865859985},{"id":"https://openalex.org/C79919700","wikidata":"https://www.wikidata.org/wiki/Q6057436","display_name":"Intervillous space","level":5,"score":0.5122913122177124},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.469310998916626},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.4562548100948334},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.45395535230636597},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.296147882938385},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24533158540725708},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.24028298258781433},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.21452778577804565},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.17732104659080505},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.12204161286354065},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0792337954044342},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004461","descriptor_name":"Eclampsia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D004461","descriptor_name":"Eclampsia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D011225","descriptor_name":"Pre-Eclampsia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014327","descriptor_name":"Trophoblasts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:21798135","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21798135","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the College of Physicians and Surgeons--Pakistan : JCPSP","raw_type":"Comparative Study"},{"id":"mag:2281925648","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21798135","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W153307768","https://openalex.org/W1578201696","https://openalex.org/W1804933064","https://openalex.org/W1975195151","https://openalex.org/W1979734620","https://openalex.org/W2015794890","https://openalex.org/W2021728568","https://openalex.org/W2061506872","https://openalex.org/W2067557867","https://openalex.org/W2073067182","https://openalex.org/W2078646575","https://openalex.org/W2115081018","https://openalex.org/W2154412334","https://openalex.org/W2322068896","https://openalex.org/W2403417853","https://openalex.org/W3203440974","https://openalex.org/W4298154816"],"related_works":["https://openalex.org/W2067557867","https://openalex.org/W7006381692","https://openalex.org/W3215278115","https://openalex.org/W2115951076","https://openalex.org/W4404709247","https://openalex.org/W4390721843","https://openalex.org/W2033572583","https://openalex.org/W1752462377","https://openalex.org/W2532061562","https://openalex.org/W3107933970"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"determine":[2],"the":[3,7,17,127,146,150,185,200],"ultrastructural":[4],"changes":[5,196],"of":[6,19,34,46,82,86,108,121,126,137,139,159,172,179,187,190,202],"placenta":[8,18],"in":[9,42,62,114,134,184,199],"women":[10,49,53,140,203],"with":[11,54,93,119,129,141,157,204],"pre-eclampsia":[12,55,205],"and":[13,50,56,67,77,97,123,161,167,177,206],"eclampsia":[14,57,207],"compared":[15,101],"to":[16,102,211],"normotensive":[20,48,103],"patients.":[21],"STUDY":[22],"DESIGN:":[23],"Comparative":[24],"descriptive":[25],"study.":[26],"PLACE":[27],"AND":[28],"DURATION":[29],"OF":[30],"STUDY:":[31],"Obstetrics":[32],"Unit":[33],"North":[35],"Colombo":[36],"Teaching":[37],"Hospital,":[38],"Ragama,":[39],"Sri":[40],"Lanka":[41],"2004.":[43],"METHODOLOGY:":[44],"Placentae":[45],"10":[47,51],"hypertensive":[52,87,115],"were":[58,72,75,132,182,197],"studied.":[59],"Morphological":[60],"abnormalities":[61],"chorionic":[63,84,109],"villi,":[64],"cytotrophoblastic":[65],"cells":[66,100,152,189],"basement":[68,106],"membrane":[69,107],"under":[70],"electronmicroscope":[71],"detected.":[73],"Findings":[74],"recorded":[76],"compared.":[78],"RESULTS:":[79],"Microvillous":[80],"surface":[81],"many":[83,94],"villi":[85,110,136],"placentae":[88,138,201],"showed":[89,153],"a":[90],"complex":[91],"appearance":[92],"distorted":[95,130],"microvilli":[96,122,131],"frequent":[98],"cytotrophoblast":[99,151],"placentae.":[104,116],"The":[105],"was":[111,148],"more":[112],"thickened":[113],"Patchy":[117],"necrosis":[118],"loss":[120,158],"gross":[124],"thinning":[125],"syncytium":[128,147],"seen":[133],"terminal":[135],"eclampsia.":[142],"In":[143],"areas":[144],"where":[145],"absent,":[149],"numerous":[154],"vacuolated":[155,180],"mitochondria":[156,181],"cristae,":[160],"few":[162],"rough":[163],"endoplasmic":[164],"reticulum,":[165],"lysosomes":[166],"glycogen":[168],"deposits.":[169],"An":[170],"accumulation":[171],"electron":[173],"dense":[174],"amorphous":[175],"substance":[176],"number":[178],"concentrated":[183],"cytoplasm":[186],"endothelial":[188],"fetal":[191],"capillaries.":[192],"CONCLUSION:":[193],"Ultrastructural":[194],"villous":[195],"found":[198],"which":[208],"are":[209],"likely":[210],"influence":[212],"adversely":[213],"on":[214],"placental":[215],"function.":[216]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":4},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}