{"id":"https://openalex.org/W2281640328","doi":"https://doi.org/10.1152/ajpendo.1991.261.6.e789","title":"Ethnic differences in sympathetic nervous system-mediated energy expenditure","display_name":"Ethnic differences in sympathetic nervous system-mediated energy expenditure","publication_year":1991,"publication_date":"1991-12-01","ids":{"openalex":"https://openalex.org/W2281640328","doi":"https://doi.org/10.1152/ajpendo.1991.261.6.e789","mag":"2281640328","pmid":"https://pubmed.ncbi.nlm.nih.gov/1685070"},"language":"en","primary_location":{"id":"doi:10.1152/ajpendo.1991.261.6.e789","doi":"https://doi.org/10.1152/ajpendo.1991.261.6.e789","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpendo.1991.261.6.e789","pdf_url":null,"source":{"id":"https://openalex.org/S196637695","display_name":"American Journal of Physiology-Endocrinology and Metabolism","issn_l":"0193-1849","issn":["0193-1849","1522-1555"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Endocrinology and Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016427083","display_name":"Mohammad F. Saad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. F. Saad","raw_affiliation_strings":["Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108346300","display_name":"Sharon A. Alger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. A. Alger","raw_affiliation_strings":["Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090204127","display_name":"FRANCESCO ZURLO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F. Zurlo","raw_affiliation_strings":["Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112158350","display_name":"J. B. Young","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. B. Young","raw_affiliation_strings":["Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058624350","display_name":"Clifton Bogardus","orcid":"https://orcid.org/0000-0003-1472-3376","observed_orcids":["https://orcid.org/0000-0003-1472-3376"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Bogardus","raw_affiliation_strings":["Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069618649","display_name":"\u00c9ric Ravussin","orcid":"https://orcid.org/0000-0003-2129-547X","observed_orcids":["https://orcid.org/0000-0003-2129-547X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E. Ravussin","raw_affiliation_strings":["Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona 85014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4886,"has_fulltext":false,"cited_by_count":83,"citation_normalized_percentile":{"value":0.90022646,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"261","issue":"6","first_page":"E789","last_page":"E794"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.3871999979019165,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.3871999979019165,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.23010000586509705,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.13850000500679016,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.8949999809265137},{"id":"https://openalex.org/keywords/energy-expenditure","display_name":"energy expenditure","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pima-indians","display_name":"Pima Indians","score":0.7940000295639038},{"id":"https://openalex.org/keywords/caucasian-men","display_name":"Caucasian men","score":0.7839999794960022},{"id":"https://openalex.org/keywords/urinary-norepinephrine","display_name":"urinary norepinephrine","score":0.9010000228881836},{"id":"https://openalex.org/keywords/beta-adrenergic-blockade","display_name":"beta-adrenergic blockade","score":0.847000002861023},{"id":"https://openalex.org/keywords/propranolol","display_name":"propranolol","score":1.0},{"id":"https://openalex.org/keywords/resting-metabolic-rate","display_name":"resting metabolic rate","score":1.0},{"id":"https://openalex.org/keywords/weight-maintenance-diet","display_name":"weight-maintenance diet","score":0.7639999985694885},{"id":"https://openalex.org/keywords/ethnic-differences","display_name":"ethnic differences","score":0.8009999990463257},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7205357551574707},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6920291185379028},{"id":"https://openalex.org/C2778151854","wikidata":"https://www.wikidata.org/wiki/Q423364","display_name":"Propranolol","level":2,"score":0.6375964283943176},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.6241286396980286},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5537704229354858},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.5132322311401367},{"id":"https://openalex.org/C2992755834","wikidata":"https://www.wikidata.org/wiki/Q4116368","display_name":"Fat free mass","level":4,"score":0.4891674816608429},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.4785352647304535},{"id":"https://openalex.org/C43376680","wikidata":"https://www.wikidata.org/wiki/Q6580786","display_name":"Bolus (digestion)","level":2,"score":0.47721773386001587},{"id":"https://openalex.org/C2988147884","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy expenditure","level":2,"score":0.42313000559806824},{"id":"https://openalex.org/C82736064","wikidata":"https://www.wikidata.org/wiki/Q623293","display_name":"Basal metabolic rate","level":2,"score":0.4166979193687439},{"id":"https://openalex.org/C2993503589","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Fat mass","level":3,"score":0.34014198184013367},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.3010725975036621},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.292418897151947},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000319","descriptor_name":"Adrenergic beta-Antagonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001481","descriptor_name":"Basal Metabolism","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005215","descriptor_name":"Fasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007198","descriptor_name":"Indians, North American","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009638","descriptor_name":"Norepinephrine","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011433","descriptor_name":"Propranolol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013564","descriptor_name":"Sympathetic Nervous System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpendo.1991.261.6.e789","doi":"https://doi.org/10.1152/ajpendo.1991.261.6.e789","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpendo.1991.261.6.e789","pdf_url":null,"source":{"id":"https://openalex.org/S196637695","display_name":"American Journal of Physiology-Endocrinology and Metabolism","issn_l":"0193-1849","issn":["0193-1849","1522-1555"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Endocrinology and Metabolism","raw_type":"journal-article"},{"id":"pmid:1685070","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1685070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2074132706","https://openalex.org/W3003770475","https://openalex.org/W2144499727","https://openalex.org/W2753818216","https://openalex.org/W56238106","https://openalex.org/W2000664453","https://openalex.org/W2414033814","https://openalex.org/W2148124324","https://openalex.org/W23033995","https://openalex.org/W2127104873"],"abstract_inverted_index":{"The":[0,32,146,202],"impact":[1],"of":[2,137,148],"sympathetic":[3],"nervous":[4],"system":[5],"(SNS)":[6],"activity":[7],"on":[8,22,164],"energy":[9],"expenditure":[10],"(EE)":[11],"was":[12,46,80,170,204],"evaluated":[13,171],"in":[14,38,48,87,96,120,131,172,206,230,239],"nondiabetic":[15],"Caucasian":[16],"and":[17,42,64,95,110,143,157,187,222,224],"Pima":[18],"Indian":[19],"men":[20],"while":[21],"a":[23,39],"weight-maintenance":[24],"diet":[25],"using":[26],"two":[27,85,208],"approaches":[28],"as":[29],"follows.":[30],"1)":[31],"relationship":[33],"between":[34,83],"24-h":[35,43,88,117],"EE,":[36],"measured":[37],"respiratory":[40],"chamber,":[41],"urinary":[44,97,118],"norepinephrine":[45,98,119],"studied":[47],"36":[49,173,181],"Caucasians":[50,121,174,231],"[32":[51],"+/-":[52,57,61,68,72,76,176,180,184,191,195,199],"8":[53],"(SD)":[54],"yr,":[55,70,178,193],"95":[56],"41":[58],"kg,":[59,74,182,197],"22":[60],"13%":[62],"fat]":[63],"33":[65],"Pimas":[66,132,189,240],"(29":[67],"6":[69,177,192],"103":[71,179],"28":[73],"30":[75],"9%":[77],"fat).":[78,201],"There":[79],"no":[81],"difference":[82],"the":[84,165,207],"groups":[86,209],"EE":[89,113],"(2,422":[90],"vs.":[91,100,211],"2,523":[92],"kcal/24":[93,213],"h)":[94,214],"(28":[99,190],"31":[101],"micrograms/24":[102],"h),":[103],"even":[104,215],"after":[105,216,227],"adjusting":[106],"for":[107,161,218],"body":[108],"size":[109],"composition.":[111],"Twenty-four-hour":[112],"correlated":[114],"significantly":[115,226],"with":[116,151],"(r":[122,133],"=":[123,134,243],"0.78,":[124],"P":[125,233,242],"less":[126,234],"than":[127,235],"0.001)":[128,236],"but":[129,237],"not":[130,238],"0.03),":[135],"independent":[136],"fat-free":[138],"mass":[139],"(FFM),":[140],"fat":[141,220],"mass,":[142,221],"age.":[144],"2)":[145],"effect":[147],"beta-adrenoceptor":[149],"blockade":[150],"propranolol":[152,228],"(120":[153],"micrograms/kg":[154],"FFM":[155],"bolus":[156],"1.2":[158],"micrograms.kg":[159],"FFM-1.min-1":[160],"45":[162],"min)":[163],"resting":[166],"metabolic":[167],"rate":[168],"(RMR)":[169],"(30":[175],"25":[183],"11%":[185],"fat)":[186],"32":[188],"100":[194],"34":[196],"27":[198],"10%":[200],"RMR":[203],"similar":[205],"(2,052":[210],"1,973":[212],"adjustment":[217],"FFM,":[219],"age":[223],"dropped":[225],"infusion":[229],"(-3.9%,":[232],"(-0.8%,":[241],"0.07).(ABSTRACT":[244],"TRUNCATED":[245],"AT":[246],"250":[247],"WORDS)":[248]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}