{"id":"https://openalex.org/W2280867404","doi":null,"title":"Novel Functions of ErbB4 and NRG-1 in Development and Cancer","display_name":"Novel Functions of ErbB4 and NRG-1 in Development and Cancer","publication_year":2013,"publication_date":"2013-03-22","ids":{"openalex":"https://openalex.org/W2280867404","mag":"2280867404"},"language":"en","primary_location":{"id":"pmh:oai:utupub.fi:11111/26798","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/26798","pdf_url":"https://www.utupub.fi/bitstreams/beef2bf3-2759-428f-a07b-b6c637339c37/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/88746","raw_type":"fi=Artikkeliv\u00e4it\u00f6skirja|en=Doctoral dissertation (article-based)|"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.utupub.fi/bitstreams/beef2bf3-2759-428f-a07b-b6c637339c37/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069911296","display_name":"Ilkka Paatero","orcid":"https://orcid.org/0000-0001-5926-2396","observed_orcids":["https://orcid.org/0000-0001-5926-2396"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ilkka Paatero","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5926-2396","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5069911296"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erbb4","display_name":"ErbB4","score":1.0},{"id":"https://openalex.org/keywords/neuregulin-1","display_name":"neuregulin-1","score":0.9800000190734863},{"id":"https://openalex.org/keywords/erbb-receptor-family","display_name":"ErbB receptor family","score":0.6499999761581421},{"id":"https://openalex.org/keywords/hif-1alpha","display_name":"HIF-1\u03b1","score":0.8669999837875366},{"id":"https://openalex.org/keywords/hypoxia-signaling","display_name":"hypoxia signaling","score":0.9919999837875366},{"id":"https://openalex.org/keywords/ligand-receptor-interactions","display_name":"ligand-receptor interactions","score":0.7260000109672546},{"id":"https://openalex.org/keywords/skeletal-muscle-development","display_name":"skeletal muscle development","score":0.7409999966621399},{"id":"https://openalex.org/keywords/zebrafish-embryos","display_name":"zebrafish embryos","score":0.8579999804496765},{"id":"https://openalex.org/keywords/serous-ovarian-cancer","display_name":"serous ovarian cancer","score":0.9810000061988831},{"id":"https://openalex.org/keywords/anchorage-independent-growth","display_name":"anchorage-independent growth","score":0.9449999928474426},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C2780943970","wikidata":"https://www.wikidata.org/wiki/Q17917202","display_name":"ERBB4","level":4,"score":0.923786997795105},{"id":"https://openalex.org/C2779251935","wikidata":"https://www.wikidata.org/wiki/Q5385089","display_name":"ErbB","level":3,"score":0.6295477747917175},{"id":"https://openalex.org/C2779438470","wikidata":"https://www.wikidata.org/wiki/Q424401","display_name":"Epidermal growth factor receptor","level":3,"score":0.5488539338111877},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5330601930618286},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5250470638275146},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5241870284080505},{"id":"https://openalex.org/C2776362946","wikidata":"https://www.wikidata.org/wiki/Q424374","display_name":"Epidermal growth factor","level":3,"score":0.5059067606925964},{"id":"https://openalex.org/C185323287","wikidata":"https://www.wikidata.org/wiki/Q59252204","display_name":"Neuregulin","level":3,"score":0.47798246145248413},{"id":"https://openalex.org/C115456853","wikidata":"https://www.wikidata.org/wiki/Q17917132","display_name":"ERBB3","level":4,"score":0.4642067551612854},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.44046199321746826},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4381955862045288},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4324226379394531},{"id":"https://openalex.org/C101544691","wikidata":"https://www.wikidata.org/wiki/Q420511","display_name":"Receptor tyrosine kinase","level":3,"score":0.41432249546051025},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2807636857032776},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10854130983352661},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10349878668785095}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:utupub.fi:11111/26798","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/26798","pdf_url":"https://www.utupub.fi/bitstreams/beef2bf3-2759-428f-a07b-b6c637339c37/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/88746","raw_type":"fi=Artikkeliv\u00e4it\u00f6skirja|en=Doctoral dissertation (article-based)|"},{"id":"pmh:oai:www.doria.fi:10024/88746","doi":null,"is_oa":false,"landing_page_url":"http://www.doria.fi/handle/10024/88746","pdf_url":null,"source":{"id":"https://openalex.org/S4377196760","display_name":"Doria (University of Helsinki)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I133731052","host_organization_name":"University of Helsinki","host_organization_lineage":["https://openalex.org/I133731052"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis (article-based)"},{"id":"pmh:oai:www.utupub.fi:10024/88746","doi":null,"is_oa":false,"landing_page_url":"http://www.utupub.fi/handle/10024/88746","pdf_url":null,"source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"fi=Artikkeliv\u00e4it\u00f6skirja|en=Doctoral dissertation (article-based)|"},{"id":"mag:2280867404","doi":null,"is_oa":false,"landing_page_url":"https://www.utupub.fi/bitstream/10024/88746/1/AnnalesD1060PaateroDISS.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utupub.fi:11111/26798","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/26798","pdf_url":"https://www.utupub.fi/bitstreams/beef2bf3-2759-428f-a07b-b6c637339c37/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/88746","raw_type":"fi=Artikkeliv\u00e4it\u00f6skirja|en=Doctoral dissertation (article-based)|"},"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320317353","display_name":"Finnish Cancer Institute","ror":"https://ror.org/02cwbja97"},{"id":"https://openalex.org/F4320321726","display_name":"Suomen Kulttuurirahasto","ror":"https://ror.org/027xav248"},{"id":"https://openalex.org/F4320323313","display_name":"Turun Yliopisto","ror":"https://ror.org/05vghhr25"},{"id":"https://openalex.org/F4320335019","display_name":"Varsinais-Suomen Rahasto","ror":"https://ror.org/027xav248"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2280867404.pdf","grobid_xml":"https://content.openalex.org/works/W2280867404.grobid-xml"},"referenced_works_count":242,"referenced_works":["https://openalex.org/W52324175","https://openalex.org/W93535044","https://openalex.org/W113659195","https://openalex.org/W161146112","https://openalex.org/W240647565","https://openalex.org/W340499956","https://openalex.org/W645508545","https://openalex.org/W1487395029","https://openalex.org/W1493048246","https://openalex.org/W1501383613","https://openalex.org/W1503667331","https://openalex.org/W1548446964","https://openalex.org/W1548640328","https://openalex.org/W1590195146","https://openalex.org/W1599969036","https://openalex.org/W1639582946","https://openalex.org/W1665419471","https://openalex.org/W1675105744","https://openalex.org/W1832030339","https://openalex.org/W1870193477","https://openalex.org/W1918680561","https://openalex.org/W1947859348","https://openalex.org/W1958742527","https://openalex.org/W1963533510","https://openalex.org/W1963811231","https://openalex.org/W1964321121","https://openalex.org/W1965647044","https://openalex.org/W1966658428","https://openalex.org/W1966928253","https://openalex.org/W1968972540","https://openalex.org/W1969734439","https://openalex.org/W1969918683","https://openalex.org/W1970211089","https://openalex.org/W1972340295","https://openalex.org/W1974024530","https://openalex.org/W1975234288","https://openalex.org/W1975984062","https://openalex.org/W1978139448","https://openalex.org/W1978859729","https://openalex.org/W1980141913","https://openalex.org/W1980911789","https://openalex.org/W1982210988","https://openalex.org/W1982411105","https://openalex.org/W1982681624","https://openalex.org/W1983048620","https://openalex.org/W1983867285","https://openalex.org/W1984469163","https://openalex.org/W1984621921","https://openalex.org/W1985103551","https://openalex.org/W1987196222","https://openalex.org/W1988142400","https://openalex.org/W1988656539","https://openalex.org/W1995527759","https://openalex.org/W1997422780","https://openalex.org/W1998756807","https://openalex.org/W2000469371","https://openalex.org/W2000489928","https://openalex.org/W2000624133","https://openalex.org/W2000815470","https://openalex.org/W2001371819","https://openalex.org/W2001968947","https://openalex.org/W2002273560","https://openalex.org/W2003131098","https://openalex.org/W2004144597","https://openalex.org/W2005868568","https://openalex.org/W2006257247","https://openalex.org/W2008161734","https://openalex.org/W2009424285","https://openalex.org/W2009635392","https://openalex.org/W2009766076","https://openalex.org/W2011033752","https://openalex.org/W2011642803","https://openalex.org/W2012911863","https://openalex.org/W2012915718","https://openalex.org/W2015722063","https://openalex.org/W2016010426","https://openalex.org/W2016046902","https://openalex.org/W2016125507","https://openalex.org/W2017079185","https://openalex.org/W2018169163","https://openalex.org/W2018204057","https://openalex.org/W2018753432","https://openalex.org/W2019751519","https://openalex.org/W2019797166","https://openalex.org/W2020237866","https://openalex.org/W2020851470","https://openalex.org/W2021656373","https://openalex.org/W2023578257","https://openalex.org/W2024348320","https://openalex.org/W2024470896","https://openalex.org/W2025357617","https://openalex.org/W2025429298","https://openalex.org/W2027877482","https://openalex.org/W2028415754","https://openalex.org/W2028496807","https://openalex.org/W2030437687","https://openalex.org/W2034269086","https://openalex.org/W2034614477","https://openalex.org/W2034887388","https://openalex.org/W2035034837","https://openalex.org/W2037632368","https://openalex.org/W2038086562","https://openalex.org/W2038661578","https://openalex.org/W2040031153","https://openalex.org/W2041102071","https://openalex.org/W2042216712","https://openalex.org/W2042996461","https://openalex.org/W2043345702","https://openalex.org/W2043474702","https://openalex.org/W2043641464","https://openalex.org/W2044146407","https://openalex.org/W2045451647","https://openalex.org/W2046609315","https://openalex.org/W2048528629","https://openalex.org/W2050461681","https://openalex.org/W2051338141","https://openalex.org/W2055149726","https://openalex.org/W2055734281","https://openalex.org/W2058021996","https://openalex.org/W2058836795","https://openalex.org/W2059513313","https://openalex.org/W2059569571","https://openalex.org/W2059951197","https://openalex.org/W2063029568","https://openalex.org/W2063867779","https://openalex.org/W2063917536","https://openalex.org/W2067376187","https://openalex.org/W2068488653","https://openalex.org/W2068555261","https://openalex.org/W2070369951","https://openalex.org/W2072451938","https://openalex.org/W2073310408","https://openalex.org/W2074320983","https://openalex.org/W2074440232","https://openalex.org/W2075059021","https://openalex.org/W2075358419","https://openalex.org/W2075711878","https://openalex.org/W2077110395","https://openalex.org/W2079438985","https://openalex.org/W2079539653","https://openalex.org/W2079681470","https://openalex.org/W2082483448","https://openalex.org/W2082677148","https://openalex.org/W2084849295","https://openalex.org/W2085189353","https://openalex.org/W2085483520","https://openalex.org/W2086248882","https://openalex.org/W2086913408","https://openalex.org/W2088035322","https://openalex.org/W2088925787","https://openalex.org/W2089692551","https://openalex.org/W2090622449","https://openalex.org/W2090650873","https://openalex.org/W2090855460","https://openalex.org/W2092025416","https://openalex.org/W2092250372","https://openalex.org/W2093189266","https://openalex.org/W2094630580","https://openalex.org/W2095059099","https://openalex.org/W2095366249","https://openalex.org/W2095879193","https://openalex.org/W2097091656","https://openalex.org/W2097685453","https://openalex.org/W2098100204","https://openalex.org/W2098972920","https://openalex.org/W2102476325","https://openalex.org/W2102718676","https://openalex.org/W2103245406","https://openalex.org/W2104812730","https://openalex.org/W2106133610","https://openalex.org/W2106186049","https://openalex.org/W2106396961","https://openalex.org/W2107427447","https://openalex.org/W2108520616","https://openalex.org/W2109492293","https://openalex.org/W2111693820","https://openalex.org/W2113508930","https://openalex.org/W2113714901","https://openalex.org/W2114536437","https://openalex.org/W2114739452","https://openalex.org/W2114920820","https://openalex.org/W2115401766","https://openalex.org/W2115844415","https://openalex.org/W2116075954","https://openalex.org/W2116903886","https://openalex.org/W2117849323","https://openalex.org/W2119352376","https://openalex.org/W2120657231","https://openalex.org/W2121136307","https://openalex.org/W2122788299","https://openalex.org/W2123415105","https://openalex.org/W2125349610","https://openalex.org/W2125947965","https://openalex.org/W2126459951","https://openalex.org/W2127115922","https://openalex.org/W2127806881","https://openalex.org/W2129355295","https://openalex.org/W2135034560","https://openalex.org/W2135198700","https://openalex.org/W2135836641","https://openalex.org/W2137168087","https://openalex.org/W2137504912","https://openalex.org/W2139420017","https://openalex.org/W2139574983","https://openalex.org/W2140486223","https://openalex.org/W2140775102","https://openalex.org/W2140840142","https://openalex.org/W2141393790","https://openalex.org/W2142564546","https://openalex.org/W2142786915","https://openalex.org/W2142826108","https://openalex.org/W2143600397","https://openalex.org/W2144196565","https://openalex.org/W2146542524","https://openalex.org/W2148974291","https://openalex.org/W2151068043","https://openalex.org/W2151625241","https://openalex.org/W2155614211","https://openalex.org/W2156495412","https://openalex.org/W2156743286","https://openalex.org/W2157981718","https://openalex.org/W2159406166","https://openalex.org/W2160120806","https://openalex.org/W2160334007","https://openalex.org/W2161533644","https://openalex.org/W2161578680","https://openalex.org/W2162419009","https://openalex.org/W2163487203","https://openalex.org/W2163509803","https://openalex.org/W2163732518","https://openalex.org/W2163798887","https://openalex.org/W2165405116","https://openalex.org/W2165562009","https://openalex.org/W2165832423","https://openalex.org/W2167132924","https://openalex.org/W2167398987","https://openalex.org/W2167761137","https://openalex.org/W2216554257","https://openalex.org/W2315705156","https://openalex.org/W2318605753","https://openalex.org/W2339389593","https://openalex.org/W2344695725"],"related_works":["https://openalex.org/W2165405116","https://openalex.org/W2167132924","https://openalex.org/W2315705156","https://openalex.org/W1583384972","https://openalex.org/W2327188447","https://openalex.org/W2085703300","https://openalex.org/W2021004463","https://openalex.org/W1531371244","https://openalex.org/W436856753","https://openalex.org/W2328039638"],"abstract_inverted_index":{"Cells":[0],"communicate,":[1],"or":[2,101],"signal,":[3],"with":[4,179,239],"each":[5],"other":[6],"constantly":[7],"to":[8,92,147,163,270],"ensure":[9],"proper":[10],"functioning":[11],"of":[12,23,48,69,72,96,103,113,117,125,138,167,173,192,204,219,234,251,267,272,275],"tissues":[13],"and":[14,25,43,54,78,86,98,109,123,130,169,175,188,228,246,262,274],"organs.":[15],"Cell":[16],"signaling":[17],"is":[18,105],"often":[19],"performed":[20],"by":[21,143],"interplay":[22],"receptors":[24,32],"ligands":[26],"that":[27,83,260],"bind":[28,39,85],"these":[29,45],"receptors.":[30],"ErbB":[31,50,74],"(epidermal":[33],"growth":[34,41,79,250],"factor":[35,132],"receptors,":[36],"EGFR,":[37],"HER)":[38],"extracellular":[40],"factors":[42],"transduce":[44],"signals":[46],"inside":[47],"cells.":[49],"dysfunction":[51],"promotes":[52],"carcinogenesis,":[53],"also":[55,161],"results":[56],"in":[57,107,155,182,184,189,195,200,202,212,215,242,255],"numerous":[58],"defects":[59,201],"during":[60],"normal":[61],"development.":[62],"This":[63,89],"study":[64,90,209],"focused":[65],"on":[66],"the":[67,73,114,118,121,135,205],"functions":[68,95,211],"one":[70],"member":[71],"receptor":[75],"family,":[76],"ErbB4,":[77,235],"factor,":[80],"neuregulin-1":[81],"(NRG-1),":[82],"can":[84],"activate":[87],"ErbB4.":[88,170],"aimed":[91],"find":[93],"novel":[94],"ErbB4":[97,129,141,176,194,210,261],"NRG-1.":[99],"Hypoxia,":[100],"deficiency":[102],"oxygen,":[104],"common":[106],"cancer":[108,245,253],"ischemic":[110],"conditions.":[111],"One":[112],"key":[115],"findings":[116],"work":[119],"was":[120,145,160,177,237],"identification":[122],"characterization":[124],"a":[126],"cross-talk":[127],"between":[128],"Hypoxia-inducible":[131],"1\u03b1":[133],"(HIF-1\u03b1),":[134],"central":[136],"mediator":[137],"hypoxia":[139],"signaling.":[140],"activation":[142],"NRG-1":[144,168,174,263],"found":[146],"increase":[148,164],"HIF-1\u03b1":[149,159],"activity.":[150],"Interestingly,":[151],"this":[152],"regulation":[153],"occurred":[154],"reciprocal":[156],"manner":[157],"as":[158],"able":[162],"protein":[165],"levels":[166],"Moreover,":[171],"expression":[172],"associated":[178,238],"HIF":[180],"activity":[181],"vivo":[183],"human":[185],"clinical":[186,217],"samples":[187,218],"mice.":[190],"Reduction":[191],"functional":[193],"developing":[196],"zebrafish":[197],"embryos":[198],"resulted":[199],"development":[203],"skeletal":[206],"muscles.":[207],"To":[208],"pathological":[213],"situation":[214],"humans,":[216],"serous":[220,243],"ovarian":[221,244,252,276],"carcinoma":[222],"were":[223],"analyzed":[224],"using":[225],"tissue":[226],"microarrays":[227],"real-time":[229],"RT-PCR.":[230],"A":[231],"specific":[232],"isoform":[233],"CYT-1,":[236],"poor":[240],"survival":[241],"increased":[247],"anchorage":[248],"independent":[249],"cells":[254],"vitro.":[256],"These":[257],"observations":[258],"demonstrate":[259],"are":[264],"essential":[265],"regulators":[266],"cellular":[268],"response":[269],"hypoxia,":[271],"development,":[273],"carcinogenesis.":[277]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}