{"id":"https://openalex.org/W2279110965","doi":null,"title":"Clinical response to a second uterine curettage in patients with low-risk gestational trophoblastic disease: a pilot study.","display_name":"Clinical response to a second uterine curettage in patients with low-risk gestational trophoblastic disease: a pilot study.","publication_year":2014,"publication_date":"2014-11-01","ids":{"openalex":"https://openalex.org/W2279110965","mag":"2279110965","pmid":"https://pubmed.ncbi.nlm.nih.gov/25552129"},"language":"en","primary_location":{"id":"pmid:25552129","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25552129","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of reproductive medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005018335","display_name":"Fariba Yarandi","orcid":"https://orcid.org/0000-0001-9882-3360","observed_orcids":["https://orcid.org/0000-0001-9882-3360"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Fariba Yarandi","raw_affiliation_strings":["Department of Obstetrics and Gynecology,  Women's Hospital, Tehran University of Medical Sciences, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology,  Women's Hospital, Tehran University of Medical Sciences, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Farzaneh Jafari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Farzaneh Jafari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090942243","display_name":"Hadi Shojaei","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hadi Shojaei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113604589","display_name":"Narges Izadi\u2010Mood","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Narges Izadi-Mood","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6703,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.71568627,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"59","issue":"11-12","first_page":"566","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gestational-trophoblastic-neoplasia","display_name":"gestational trophoblastic neoplasia","score":0.984000027179718},{"id":"https://openalex.org/keywords/uterine-evacuation","display_name":"uterine evacuation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/chemotherapy-avoidance","display_name":"chemotherapy avoidance","score":0.5849999785423279},{"id":"https://openalex.org/keywords/dactinomycin","display_name":"actinomycin D","score":0.9539999961853027},{"id":"https://openalex.org/keywords/complete-remission","display_name":"complete remission","score":0.9330000281333923},{"id":"https://openalex.org/keywords/uterine-perforation","display_name":"uterine perforation","score":0.8999999761581421}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9410923719406128},{"id":"https://openalex.org/C2779904257","wikidata":"https://www.wikidata.org/wiki/Q1428130","display_name":"Curettage","level":2,"score":0.7267236113548279},{"id":"https://openalex.org/C2781310275","wikidata":"https://www.wikidata.org/wiki/Q3918693","display_name":"Uterine perforation","level":5,"score":0.7176024913787842},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6766822934150696},{"id":"https://openalex.org/C2778383414","wikidata":"https://www.wikidata.org/wiki/Q3433884","display_name":"Gestational trophoblastic disease","level":4,"score":0.5455460548400879},{"id":"https://openalex.org/C2778456384","wikidata":"https://www.wikidata.org/wiki/Q1508510","display_name":"Perforation","level":3,"score":0.47078603506088257},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.47043630480766296},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.46656671166419983},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4356166124343872},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.41235288977622986},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4085853099822998},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.34895336627960205},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.12608996033668518},{"id":"https://openalex.org/C2779076696","wikidata":"https://www.wikidata.org/wiki/Q1280670","display_name":"Family planning","level":4,"score":0.0622921884059906},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C2778527123","wikidata":"https://www.wikidata.org/wiki/Q11750728","display_name":"Punching","level":2,"score":0.0},{"id":"https://openalex.org/C2986817661","wikidata":"https://www.wikidata.org/wiki/Q185698","display_name":"Research methodology","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004107","descriptor_name":"Dilatation and Curettage","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012086","descriptor_name":"Reoperation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D014599","descriptor_name":"Uterus","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D031901","descriptor_name":"Gestational Trophoblastic Disease","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:25552129","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25552129","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of reproductive medicine","raw_type":"Journal Article"},{"id":"mag:2279110965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25552129","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2989270401","https://openalex.org/W2515852356","https://openalex.org/W4312465454","https://openalex.org/W4312139173","https://openalex.org/W2760113895","https://openalex.org/W3112933155","https://openalex.org/W2938676364","https://openalex.org/W2980011846","https://openalex.org/W4387077392","https://openalex.org/W3110913383"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"determine":[2],"the":[3,30,86,119],"curative":[4],"effect":[5],"of":[6,33,58],"a":[7,42,126,133,142],"repeat":[8],"uterine":[9,54,127],"evacuation":[10,55],"in":[11,41,145,150],"patients":[12,68,81,102,146],"with":[13,21,93,115,147,172],"low-risk":[14,22,148],"gestational":[15,23],"trophoblastic":[16,24],"neoplasia.":[17],"STUDY":[18],"DESIGN:":[19],"Patients":[20],"neoplasia":[25],"(GTN)(N=12),":[26],"diagnosed":[27],"according":[28],"to":[29,62,83,85,104,140],"International":[31],"Federation":[32],"Gynecology":[34],"and":[35,56,74,89,160,166],"Obstetrics":[36],"2002":[37],"guidelines,":[38],"were":[39,48,75],"enrolled":[40],"prospective":[43],"cohort":[44],"study.":[45],"Primary":[46],"outcomes":[47],"need":[49],"for":[50],"chemotherapy":[51,59,73,92,105],"after":[52],"second":[53,78,87,143],"number":[57],"courses":[60],"needed":[61],"achieve":[63],"complete":[64],"remission.":[65],"RESULTS:":[66],"Ten":[67],"(83%)":[69],"did":[70],"not":[71],"require":[72],"cured":[76],"bya":[77],"curettage.":[79],"Two":[80],"failed":[82],"respond":[84],"curettage":[88,131,144],"received":[90],"single-agent":[91],"actinomycin-D":[94],"(1.25":[95],"mg/m2":[96],"biweekly,":[97],"slow":[98],"intravenous":[99],"administration).":[100],"Both":[101],"responded":[103],"as":[106],"second-line":[107],"therapy.":[108],"A":[109],"100%":[110],"remission":[111],"rate":[112],"was":[113],"achieved,":[114],"no":[116],"recurrence":[117],"at":[118],"1-year":[120],"follow-up.":[121],"One":[122],"patient":[123],"(8%)":[124],"had":[125],"perforation.":[128],"CONCLUSION:":[129],"Second":[130],"has":[132],"favorable":[134],"response":[135],"rate.":[136],"It":[137],"seems":[138],"reasonable":[139],"perform":[141],"GTN":[149],"settings":[151],"where":[152],"serum":[153],"beta-hCG":[154],"assay":[155],"follow-up":[156],"is":[157],"highly":[158],"reliable":[159],"available.":[161],"However,":[162],"its":[163],"potential":[164],"complications":[165],"inconvenience":[167],"must":[168],"be":[169],"discussed":[170],"critically":[171],"each":[173],"patient.":[174]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}