{"id":"https://openalex.org/W2278680954","doi":null,"title":"Nanoencapsulation of Tea Catechins in Casein Micelles: Effects on Processing and Biological Functionalities","display_name":"Nanoencapsulation of Tea Catechins in Casein Micelles: Effects on Processing and Biological Functionalities","publication_year":2012,"publication_date":"2012-11-25","ids":{"openalex":"https://openalex.org/W2278680954","mag":"2278680954"},"language":"en","primary_location":{"id":"pmh:oai:atrium.lib.uoguelph.ca:10214/4871","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10214/4871","pdf_url":null,"source":{"id":"https://openalex.org/S4306401043","display_name":"The Atrium (University of Guelph)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79817857","host_organization_name":"University of Guelph","host_organization_lineage":["https://openalex.org/I79817857"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064438260","display_name":"Sanaz Haratifar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sanaz Haratifar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5064438260"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10411","display_name":"Proteins in Food Systems","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.009499999694526196,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12048","display_name":"Microencapsulation and Drying Processes","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nanoencapsulation","display_name":"nanoencapsulation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/tea-catechins","display_name":"tea catechins","score":0.972000002861023},{"id":"https://openalex.org/keywords/casein-micelles","display_name":"casein micelles","score":0.8870000243186951},{"id":"https://openalex.org/keywords/epigallocatechin-gallate","display_name":"epigallocatechin gallate","score":0.9210000038146973},{"id":"https://openalex.org/keywords/milk-protein","display_name":"milk protein","score":0.8159999847412109},{"id":"https://openalex.org/keywords/protein-ligand-binding","display_name":"protein-ligand binding","score":0.675000011920929},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.6620000004768372},{"id":"https://openalex.org/keywords/colon-cancer-cells","display_name":"colon cancer cells","score":0.8500000238418579},{"id":"https://openalex.org/keywords/ht-29-cells","display_name":"HT-29 cells","score":0.9580000042915344},{"id":"https://openalex.org/keywords/in-vitro-digestion","display_name":"in vitro digestion","score":0.7710000276565552},{"id":"https://openalex.org/keywords/bioactive-compound-delivery","display_name":"bioactive compound delivery","score":0.7649999856948853}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5261791944503784},{"id":"https://openalex.org/C11268172","wikidata":"https://www.wikidata.org/wiki/Q421110","display_name":"Micelle","level":3,"score":0.5205234289169312},{"id":"https://openalex.org/C2776142715","wikidata":"https://www.wikidata.org/wiki/Q193970","display_name":"Casein","level":2,"score":0.4361688792705536},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.4310583472251892},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.33162644505500793},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.19794756174087524},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:atrium.lib.uoguelph.ca:10214/4871","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10214/4871","pdf_url":null,"source":{"id":"https://openalex.org/S4306401043","display_name":"The Atrium (University of Guelph)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79817857","host_organization_name":"University of Guelph","host_organization_lineage":["https://openalex.org/I79817857"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:oai:collectionscanada.gc.ca:OGU.10214/4871","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10214/4871","pdf_url":null,"source":{"id":"https://openalex.org/S4306402307","display_name":"Library and Archives Canada (Government of Canada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2802286613","host_organization_name":"Government of Canada","host_organization_lineage":["https://openalex.org/I2802286613"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2278680954","doi":null,"is_oa":false,"landing_page_url":"https://atrium.lib.uoguelph.ca/xmlui/handle/10214/4871","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":102,"referenced_works":["https://openalex.org/W17323408","https://openalex.org/W571677811","https://openalex.org/W615819422","https://openalex.org/W1501166132","https://openalex.org/W1959163136","https://openalex.org/W1964952272","https://openalex.org/W1971005475","https://openalex.org/W1971417259","https://openalex.org/W1971895399","https://openalex.org/W1973900565","https://openalex.org/W1974810494","https://openalex.org/W1976250607","https://openalex.org/W1977037331","https://openalex.org/W1981157132","https://openalex.org/W1981171010","https://openalex.org/W1982098995","https://openalex.org/W1986269044","https://openalex.org/W1989839093","https://openalex.org/W1992409616","https://openalex.org/W1994625025","https://openalex.org/W1996440127","https://openalex.org/W1998971200","https://openalex.org/W2001815014","https://openalex.org/W2008319673","https://openalex.org/W2013335354","https://openalex.org/W2013812389","https://openalex.org/W2014114876","https://openalex.org/W2018607875","https://openalex.org/W2019727669","https://openalex.org/W2020328407","https://openalex.org/W2020494266","https://openalex.org/W2020606719","https://openalex.org/W2021341863","https://openalex.org/W2022072020","https://openalex.org/W2024498680","https://openalex.org/W2026362591","https://openalex.org/W2026692084","https://openalex.org/W2027732780","https://openalex.org/W2034710312","https://openalex.org/W2035277609","https://openalex.org/W2035417580","https://openalex.org/W2037833415","https://openalex.org/W2041641105","https://openalex.org/W2042873064","https://openalex.org/W2047906915","https://openalex.org/W2048005672","https://openalex.org/W2049728393","https://openalex.org/W2052201651","https://openalex.org/W2054042395","https://openalex.org/W2066494134","https://openalex.org/W2067266295","https://openalex.org/W2067488430","https://openalex.org/W2069789267","https://openalex.org/W2071048467","https://openalex.org/W2071440115","https://openalex.org/W2072643110","https://openalex.org/W2076893264","https://openalex.org/W2078723138","https://openalex.org/W2080627325","https://openalex.org/W2083177668","https://openalex.org/W2084085849","https://openalex.org/W2085715270","https://openalex.org/W2086868978","https://openalex.org/W2087692771","https://openalex.org/W2089906158","https://openalex.org/W2093974041","https://openalex.org/W2101253668","https://openalex.org/W2102565160","https://openalex.org/W2105408725","https://openalex.org/W2105966479","https://openalex.org/W2109689528","https://openalex.org/W2113018723","https://openalex.org/W2113140652","https://openalex.org/W2114517267","https://openalex.org/W2115154144","https://openalex.org/W2120181084","https://openalex.org/W2124045186","https://openalex.org/W2124510560","https://openalex.org/W2130514425","https://openalex.org/W2134857618","https://openalex.org/W2135782311","https://openalex.org/W2136865018","https://openalex.org/W2143999360","https://openalex.org/W2144675115","https://openalex.org/W2148042269","https://openalex.org/W2148313291","https://openalex.org/W2152252699","https://openalex.org/W2152835156","https://openalex.org/W2153480732","https://openalex.org/W2154621970","https://openalex.org/W2160012138","https://openalex.org/W2160788531","https://openalex.org/W2165918189","https://openalex.org/W2167212038","https://openalex.org/W2167561104","https://openalex.org/W2168132502","https://openalex.org/W2168268365","https://openalex.org/W2269716589","https://openalex.org/W2319167906","https://openalex.org/W2467987796","https://openalex.org/W2594162906","https://openalex.org/W4254758362"],"related_works":["https://openalex.org/W2042269323","https://openalex.org/W2084395128","https://openalex.org/W2038093613","https://openalex.org/W2032466476","https://openalex.org/W2018271318","https://openalex.org/W2911259432","https://openalex.org/W7167444988","https://openalex.org/W4386257131","https://openalex.org/W2551257419","https://openalex.org/W2317878996"],"abstract_inverted_index":{"This":[0],"thesis":[1],"focuses":[2],"on":[3,19,31,125,169,207,261,271],"the":[4,14,17,20,32,36,73,84,92,103,112,116,152,160,170,179,197,240,243,249,266,301],"interactions":[5,18],"between":[6],"milk":[7,88,244,292],"proteins":[8],"(caseins)":[9],"and":[10,13,23,56,59,181,214],"tea":[11],"catechins":[12],"consequences":[15],"of":[16,25,35,46,67,83,96,106,115,131,154,162,164,173,184,199,242,251,269,303],"renneting":[21],"properties":[22],"digestion":[24,241],"casein":[26,50,74,134,167],"micelles":[27,51,98,135,168],"as":[28,30,38,141,256,296],"well":[29],"biological":[33,171],"functionality":[34,172],"mixture,":[37],"measured":[39],"using":[40,54],"intestinal":[41],"cell":[42,263,276],"models.":[43],"The":[44,94,231],"binding":[45,236],"epigallocatechin-gallate":[47],"(EGCG)":[48],"to":[49,87,121,226],"was":[52,61,89,175,190,224,253,280],"quantified":[53],"HPLC":[55],"fluorescence":[57],"quenching,":[58],"it":[60,148],"shown":[62],"that":[63,192,234,291],"a":[64,211],"substantial":[65],"amount":[66],"EGCG":[68,85,118,132,165,174,223,252,270,279],"can":[69,293],"be":[70,294],"incorporated":[71],"in":[72,133,166,227],"micelles.":[75],"At":[76],"concentrations":[77],"<":[78],"2.5":[79],"mg/ml":[80],"milk,":[81,107],"most":[82],"added":[86],"associated":[90],"with":[91,284],"caseins.":[93],"formation":[95,114],"EGCG-casein":[97,235],"complexes":[99],"not":[100,195,238,254],"only":[101],"delayed":[102],"gelling":[104],"point":[105],"but":[108],"they":[109],"also":[110,150,204],"affected":[111],"structure":[113],"gels.":[117],"is":[119],"known":[120],"have":[122,137],"antiproliferative":[123],"activity":[124],"colon":[126,186],"cancer":[127,187,272],"cells.":[128,188],"Although":[129],"nanoencapsulation":[130,163,193],"may":[136,149],"some":[138],"advantages,":[139],"such":[140],"protecting":[142],"this":[143,158,220,247],"bioactive":[144,304],"compound":[145],"from":[146],"degradation,":[147],"affect":[151,196,239],"bioavailability":[153],"EGCG.":[155,200],"To":[156],"test":[157],"hypothesis,":[159],"effect":[161,268],"tested":[176],"by":[177],"evaluating":[178],"cytotoxity":[180],"proliferation":[182],"behaviour":[183],"HT-29":[185],"It":[189],"demonstrated":[191,265],"did":[194,237],"bioefficacy":[198,250],"Similar":[201],"experiments":[202,287],"were":[203],"carried":[205],"out":[206],"rat":[208],"colonic":[209],"cells,":[210,273],"normal":[212,262,275],"line":[213],"its":[215],"cancerous":[216],"tranformed":[217],"line.":[218],"For":[219],"study,":[221],"nanoencapulated":[222],"subjected":[225],"vitro":[228],"digbefore":[229],"absorption.":[230],"results":[232],"showed":[233],"proteins.":[245],"In":[246,258],"case,":[248],"diminished":[255],"well.":[257],"addition,":[259],"studies":[260],"lines":[264],"specific":[267],"favoring":[274],"survival":[277],"whether":[278],"isolated":[281],"or":[282],"complexed":[283],"milk.":[285],"These":[286],"bring":[288],"further":[289],"evidence":[290],"employed":[295],"an":[297],"appropriate":[298],"platform":[299],"for":[300],"delivery":[302],"compounds.":[305]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
