{"id":"https://openalex.org/W2276846476","doi":null,"title":"Vitamin D, Physical Performance and Neuropsychological Functioning in Elderly Subjects:The Pro.V.A Study","display_name":"Vitamin D, Physical Performance and Neuropsychological Functioning in Elderly Subjects:The Pro.V.A Study","publication_year":2013,"publication_date":"2013-01-25","ids":{"openalex":"https://openalex.org/W2276846476","mag":"2276846476"},"language":"en","primary_location":{"id":"pmh:oai:www.research.unipd.it:11577/3422651","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11577/3422651","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11577/3422651","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104671065","display_name":"Elena Debora Toffanello","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Elena Debora Toffanello","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5104671065"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13112","display_name":"Nutrition and Health Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.8130000233650208},{"id":"https://openalex.org/keywords/25-hydroxyvitamin-d","display_name":"25-hydroxyvitamin D","score":0.996999979019165},{"id":"https://openalex.org/keywords/physical-performance","display_name":"physical performance","score":0.6480000019073486},{"id":"https://openalex.org/keywords/neuropsychological-performance","display_name":"neuropsychological performance","score":0.7390000224113464},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.9279999732971191},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.8669999837875366},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.6499999761581421},{"id":"https://openalex.org/keywords/balance","display_name":"balance","score":0.675000011920929},{"id":"https://openalex.org/keywords/walking-speed","display_name":"walking speed","score":0.9959999918937683},{"id":"https://openalex.org/keywords/muscle-strength","display_name":"muscle strength","score":0.7570000290870667},{"id":"https://openalex.org/keywords/vitamin-d-supplementation","display_name":"vitamin D supplementation","score":0.6909999847412109},{"id":"https://openalex.org/keywords/community-dwelling-elderly","display_name":"community-dwelling older adults","score":0.7850000262260437},{"id":"https://openalex.org/keywords/vitamin-d-receptor","display_name":"vitamin D receptor","score":0.48899999260902405},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8040000200271606},{"id":"https://openalex.org/keywords/mobility-impairment","display_name":"mobility impairment","score":0.48500001430511475},{"id":"https://openalex.org/keywords/vitamin-d-excess","display_name":"vitamin D excess","score":0.3370000123977661},{"id":"https://openalex.org/keywords/mood","display_name":"mood","score":0.39399999380111694}],"concepts":[{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.7215068340301514},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46997255086898804},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.46635428071022034},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42599019408226013},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.35444116592407227},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.262745201587677},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.26064759492874146},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15900856256484985}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:www.research.unipd.it:11577/3422651","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11577/3422651","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2276846476","doi":null,"is_oa":false,"landing_page_url":"http://paduaresearch.cab.unipd.it/5498/1/TOFFANELLO_ELENA_TESI.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:www.research.unipd.it:11577/3422651","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11577/3422651","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":89,"referenced_works":["https://openalex.org/W53959218","https://openalex.org/W55127047","https://openalex.org/W1487935461","https://openalex.org/W1511144845","https://openalex.org/W1517902812","https://openalex.org/W1531695673","https://openalex.org/W1547636099","https://openalex.org/W1761274382","https://openalex.org/W1847168837","https://openalex.org/W1952582346","https://openalex.org/W1967546229","https://openalex.org/W1968397534","https://openalex.org/W1979851608","https://openalex.org/W1981262591","https://openalex.org/W1981578725","https://openalex.org/W1991176283","https://openalex.org/W1991405324","https://openalex.org/W2001167462","https://openalex.org/W2006643282","https://openalex.org/W2009369892","https://openalex.org/W2013570006","https://openalex.org/W2027298487","https://openalex.org/W2027504071","https://openalex.org/W2032288122","https://openalex.org/W2032660040","https://openalex.org/W2035644659","https://openalex.org/W2043828514","https://openalex.org/W2045392324","https://openalex.org/W2046848185","https://openalex.org/W2047334039","https://openalex.org/W2050144748","https://openalex.org/W2050461841","https://openalex.org/W2053130595","https://openalex.org/W2054934202","https://openalex.org/W2058632081","https://openalex.org/W2058871858","https://openalex.org/W2059087242","https://openalex.org/W2060531348","https://openalex.org/W2063927547","https://openalex.org/W2080845515","https://openalex.org/W2087559183","https://openalex.org/W2091534885","https://openalex.org/W2096657471","https://openalex.org/W2101042105","https://openalex.org/W2104234101","https://openalex.org/W2105071925","https://openalex.org/W2109909789","https://openalex.org/W2111373412","https://openalex.org/W2112519660","https://openalex.org/W2112837687","https://openalex.org/W2119739932","https://openalex.org/W2119960796","https://openalex.org/W2122593814","https://openalex.org/W2123263258","https://openalex.org/W2123642256","https://openalex.org/W2124070987","https://openalex.org/W2126487639","https://openalex.org/W2131239091","https://openalex.org/W2131264460","https://openalex.org/W2131293625","https://openalex.org/W2131771870","https://openalex.org/W2133371501","https://openalex.org/W2133817813","https://openalex.org/W2134117346","https://openalex.org/W2134894631","https://openalex.org/W2135268750","https://openalex.org/W2135816456","https://openalex.org/W2136324974","https://openalex.org/W2142155191","https://openalex.org/W2142971300","https://openalex.org/W2144217189","https://openalex.org/W2144942859","https://openalex.org/W2145731558","https://openalex.org/W2145891298","https://openalex.org/W2146069778","https://openalex.org/W2148865473","https://openalex.org/W2149002351","https://openalex.org/W2150399991","https://openalex.org/W2154443522","https://openalex.org/W2154997944","https://openalex.org/W2156910304","https://openalex.org/W2158554024","https://openalex.org/W2159011576","https://openalex.org/W2159969435","https://openalex.org/W2161941977","https://openalex.org/W2164305641","https://openalex.org/W2172106147","https://openalex.org/W2399080559","https://openalex.org/W2981592749"],"related_works":["https://openalex.org/W7015951373","https://openalex.org/W1979915614","https://openalex.org/W2122593814","https://openalex.org/W7096320102","https://openalex.org/W2320994652","https://openalex.org/W7097971893","https://openalex.org/W7115702655","https://openalex.org/W230836116","https://openalex.org/W2145731558","https://openalex.org/W38566499"],"abstract_inverted_index":{"BACKGROUND":[0],"In":[1,1130,1224,1361,1391],"the":[2,11,37,71,101,132,137,171,210,219,227,236,250,283,359,364,374,420,480,492,526,541,563,611,642,653,681,707,716,724,758,788,795,882,885,889,892,911,925,937,960,968,1036,1049,1104,1120,1149,1231,1262,1279,1291,1316,1322,1333,1427,1442,1453,1456,1459,1487],"past":[3],"two":[4,379],"decades,":[5],"it":[6,1285],"has":[7,66,123],"become":[8,124],"evident":[9,1034],"that":[10,83,1383],"role":[12],"of":[13,39,73,87,131,152,181,216,233,240,258,317,507,531,548,552,610,613,657,665,670,760,775,809,820,884,891,904,908,921,951,1112,1119,1128,1148,1169,1187,1414,1435,1455,1463,1490],"vitamin":[14,60,104,140,619,666,745,1170],"D":[15,21,50,89,141,620,667,746,872,1171,1484],"extends":[16],"beyond":[17],"calcium":[18],"homoeostasis.1":[19],"Vitamin":[20,49,871,1483],"metabolites":[22],"have":[23,81,164,1255],"been":[24,165],"found":[25,984,1481],"to":[26,53,135,208,225,297,340,362,395,410,487,499,521,679,744,756,764,786,806,1102,1125,1144,1157,1173,1180,1183,1254,1309,1324,1444],"affect":[27],"muscle":[28,42,46,453],"metabolism":[29],"by":[30,478,511,539,659,1400],"stimulating":[31],"de":[32],"novo":[33],"protein":[34],"synthesis,":[35],"increasing":[36,1110,1167],"proportion":[38],"type":[40],"II":[41],"fibers":[43],"and":[44,59,96,111,117,143,145,177,191,195,198,218,235,262,270,311,335,343,428,449,475,495,513,528,545,571,593,595,601,608,629,687,709,727,794,838,863,887,906,931,933,964,977,999,1009,1026,1055,1060,1071,1078,1089,1096,1117,1216,1220,1338,1350,1458,1486],"improving":[45],"function.2":[47],"Moreover":[48],"receptors":[51],"seem":[52],"be":[54],"widespread":[55],"in":[56,120,148,300,321,324,366,378,390,424,433,503,517,525,636,706,723,772,799,861,869,881,888,902,936,967,992,995,1006,1017,1020,1039,1043,1046,1052,1064,1068,1093,1114,1134,1164,1190,1197,1209,1278,1290,1378,1385,1471],"brain":[57],"tissue":[58],"D\u2019s":[61],"biologically":[62],"active":[63],"form":[64],"(1,25OHD3)":[65],"shown":[67,82,1067,1082],"neuroprotective":[68],"effects":[69],"including":[70],"clearance":[72],"amyloid":[74],"plaques.3":[75],"Clinical":[76],"studies":[77],"on":[78,266,1261,1315],"older":[79,154,824],"people":[80],"low":[84],"serum":[85,175,201,214,231,615,761,791,852,1185],"levels":[86,176,202,215,232,616,686,698,719,763,793,976,1111,1142,1186,1206,1215,1337,1462],"25-hydroxyvitamin":[88],"(25OHD)":[90],"correlate":[91],"with":[92,97,352,515,696,828,841,1109,1166,1296,1346,1396],"poorer":[93],"motor":[94,144,739,1200],"performances":[95,279,1201],"cognitive":[98,116,222,269,501,518,766,927,940,1218,1259,1313,1339,1357,1379],"decline.4-10":[99],"Therefore":[100],"association":[102,138,211,228,683,789,1074,1268,1334,1479],"between":[103,139,173,212,229,655,684,790,929,974,1075,1123,1213,1335,1461,1482],"D,":[105],"performance":[106,183,206,276,376,688,740,978,1079],"tests":[107,184,689,1092],"exploring":[108,114],"mobility":[109,205],"impairments":[110],"neuropsychological":[112,146,497,691],"test":[113,490,741,987,1001,1038,1051,1106,1380],"both":[115,1007,1040,1191,1210,1347],"depression":[118,241,810,971,1223,1491],"mood":[119,1492],"elderly":[121,260,725,915],"subjects":[122],"a":[125,149,178,304,307,312,385,438,458,546,572,731,770,829,842,919,949,1028,1256,1297,1311,1376],"clinically":[126],"hot":[127],"topic.":[128],"The":[129,161,255,315,815,850,1073,1099,1176,1411,1432],"purpose":[130],"study":[133,817],"was":[134,326,368,388,435,471,509,537,550,576,855,879,900,1032,1269,1286,1341,1422,1426,1437],"verify":[136],"status":[142,747,1485],"functioning":[147],"large":[150,179],"sample":[151,256,1323,1443],"Italian":[153],"people.":[155],"SPECIFIC":[156],"AIMS":[157],"OF":[158],"THE":[159],"STUDY":[160],"following":[162,284],"aims":[163],"taken":[166,361,1101],"into":[167],"considerations:":[168],"1.":[169],"testing":[170],"relationship":[172,759],"25OHD":[174,200,217,234,614,685,697,718,762,853,975,1076,1113,1141,1184,1205,1214,1281,1293,1336,1348,1373,1387,1397,1409,1420,1464],"battery":[180],"physical":[182,267],"(exploring":[185],"balance,":[186],"gait":[187,997,1057,1085,1136],"speed,":[188,372,1086],"coordination,":[189],"upper":[190],"lower":[192,1467],"limb":[193],"strength":[194,1012,1062,1091,1162],"aerobic":[196],"capacity)":[197],"identify":[199,715,807],"optimal":[203],"for":[204,245,416,578,590,597,605,618,648,704,720,738,939,970,985,989,1003,1010,1014,1024,1035,1048,1056,1083,1140,1204,1222,1230,1276,1356,1365,1416],"2.":[207],"explore":[209,226],"baseline":[213,230,474,816,1232,1330,1366],"4y":[220,237,797,1257],"subsequent":[221,238,1488],"decline":[223,771,941,1219,1260,1314,1340,1358,1377,1415,1457],"3.":[224],"development":[239],"mood.":[242],"METHODS":[243],"Data":[244],"this":[246],"analysis":[247,556,559,669,735,938],"are":[248],"from":[249,1155],"Progetto":[251],"Veneto":[252],"Anziani":[253],"(Pro.V.A.).11":[254],"consisted":[257,819],"community-dwelling":[259],"men":[261,726,840,1131,1165],"women":[263,827,886,905,1053,1115],"whose":[264],"data":[265],"performance,":[268],"psychological":[271],"evaluation":[272],"were":[273,280,295,338,393,408,455,560,583,603,639,650,677,702,712,736,754,784,804,934,965,983,1202,1237,1245,1251,1300,1327,1352,1372,1408,1419,1447,1465,1480],"complete.":[274],"Motor":[275],"assessment:":[277],"Physical":[278],"evaluated":[281,472,538],"using":[282,437,457,540,562,585,641,668],"standardized":[285],"tests:11":[286],"\uf0f1":[287,328,370,400,426],"Tandem":[288],"test,":[289,365,403],"TT":[290],"(static":[291],"balance":[292,299],"ability):":[293],"participants":[294,337,407,923,1235,1325,1395,1406,1445],"asked":[296,339,409],"maintain":[298],"three":[301],"different":[302],"positions:":[303],"side-by-side":[305],"position,":[306,310],"semi":[308],"tandem":[309],"full-tandem":[313],"position.":[314],"amount":[316,1454],"time":[318,360,1100],"they":[319,422],"succeeded":[320],"remaining":[322],"so,":[323],"seconds,":[325,367],"recorded;":[327,369],"5":[329,346],"timed":[330],"chair":[331],"stands,":[332],"TCS":[333,986,1050,1105],"(coordination":[334],"strength):":[336],"stand":[341],"up":[342,1143,1172,1182],"sit":[344],"down":[345],"times":[347],"as":[348,350,769,1066,1425],"quickly":[349],"possible,":[351],"their":[353,357,413],"hands":[354],"folded":[355],"across":[356,1430],"chest;":[358],"complete":[363,1103],"Gait":[371],"GS:":[373],"best":[375,717],"achieved":[377],"walks":[380],"at":[381,412,473,476,748,780,812,917,1152,1319,1329,1353,1359,1449,1493],"usual":[382,414],"pace":[383,415],"along":[384],"4m":[386],"corridor":[387],"recorded":[389],"meter/seconds.":[391],"Participants":[392,1295,1345],"allowed":[394],"use":[396],"canes":[397],"or":[398,617,661,690,777,1242],"walkers;":[399],"6-minute":[401],"walking":[402],"6mW":[404,1000,1037,1087,1177],"(aerobic":[405],"capacity):":[406],"walk":[411],"6":[417],"minutes,":[418],"recording":[419],"distance":[421,1088,1178],"covered":[423],"meters;":[425],"Handgrip":[427,1161],"quadriceps":[429],"strength:":[430],"handgrip":[431,1011,1061,1090],"strength,":[432],"kg,":[434],"measured":[436],"JAMAR":[439],"hand-held":[440],"dynamometer":[441,461],"(BK-7498,":[442],"Fred":[443,463],"Sammons,":[444,464],"Inc.).":[445,465],"Knee":[446],"extensor":[447],"(quadriceps)":[448],"hip":[450],"flexor":[451],"(iliopsoas)":[452],"strengths":[454],"determined":[456],"Nicholas":[459],"Manual":[460,530],"(BK-7454,":[462],"Neuropsychological":[466],"Functioning":[467],"Assessment:":[468],"Cognitive":[469],"function":[470,502],"follow-up,":[477,944],"administering":[479],"30-item":[481],"Mini":[482],"Mental":[483,532],"State":[484],"Examination,":[485],"according":[486,520],"Folstein.12":[488],"This":[489,1267],"is":[491,1081],"most":[493,1118,1147],"widely":[494],"validated":[496],"tool":[498],"measure":[500,979],"geriatric":[504],"setting.":[505],"Diagnosis":[506],"dementia":[508],"performed":[510,561,737],"geretricians":[512],"psychologists":[514],"expertise":[516],"impairment":[519],"criteria":[522],"set":[523],"out":[524],"Diagnostic":[527],"Statistical":[529,555],"Disorders":[533],"(Fourth":[534],"Edition).13":[535],"Depression":[536,543],"Geriatric":[542],"Scale,":[544],"score":[547,774,1318,1368],"\u226511":[549],"indicative":[551],"depressive":[553],"symptoms.14":[554],"All":[557],"statistical":[558,579],"SAS":[564,569],"rel.":[565],"9.13":[566],"(Cary":[567],"NC:":[568],"institute),":[570],"two-tailed":[573],"p-value":[574],"<.05":[575],"assumed":[577],"significance.":[580],"Participants\u2019":[581],"characteristics":[582],"summarized":[584],"means":[586,656],"(\u00b1":[587],"standard":[588],"deviations)":[589],"continuous":[591],"variables":[592,638],"counts":[594],"percentages":[596],"categorical":[598,637],"variables.":[599],"Means":[600],"proportions":[602],"calculated":[604],"sex-specific":[606],"quintiles":[607],"tertiles":[609],"distribution":[612],"clinical":[621,662],"cut-off":[622],"values":[623,647,664],"(deficient":[624],"<50":[625,876],"nmol/L,":[626,631,1146,1208],"insufficient":[627,1243,1292],">50":[628],"<75":[630],"sufficient":[632,1308,1388],">75":[633],"nmol/L).15":[634],"Differences":[635],"examined":[640,703],"Chi-square":[643],"test.":[644],"Age-adjusted":[645],"p":[646],"trends":[649],"calculated,":[651],"checking":[652],"differences":[654,1460],"covariates":[658,1277],"quintiles/tertiles":[660],"cut-offs":[663],"variance":[671],"(ANOVA).":[672],"General":[673],"linear":[674,981,1030,1428],"models":[675,711,753,783,803,1227,1363],"(GLM)":[676],"used":[678,755],"examine":[680,787],"independent":[682],"function.":[692],"Known":[693],"factors":[694],"associated":[695,743],"and/or":[699],"physical/cognitive":[700],"functionality":[701],"inclusion":[705],"analyses":[708,969],"multivariate":[710],"obtained.":[713],"To":[714],"musculoskeletal":[721],"functions":[722],"women,":[728,862,1135],"we":[729,1440],"conducted":[730],"loess":[732],"analysis.":[733],"Longitudinal":[734],"significantly":[742,1108,1139],"baseline.":[749],"Multivariate":[750],"logistic":[751,1225],"regression":[752,1226,1476],"determine":[757],"substantial":[765,1258,1312],"decline,":[767],"defined":[768],"MMSE":[773,800,1233,1263,1317,1367,1402],"3":[776],"more":[778,1246,1303,1343,1404],"points":[779,1403],"follow-up.":[781,813,1320],"Random-effects":[782],"applied":[785],"25(OH)D":[792,1238,1252,1298,1307],"mean":[796,830,843,851],"changing":[798],"scores.":[801],"Cox-regression":[802],"obtained":[805],"predictors":[808],"onset":[811],"RESULTS":[814],"population":[818],"2694":[821,912],"community":[822,913],"dwelling":[823,914],"people:":[825],"1597":[826],"age":[831,844,955],"75.6":[832],"y":[833,846,957],"\u00b17.5":[834],"(range":[835,848],"65-98":[836],"y)":[837],"1097":[839],"76.2":[845],"\u00b17.8":[847],"65-99).":[849],"level":[854,875,1168],"65.0":[856],"nmol/L":[857,865,877,1127,1189],"(\u00b141.3;":[858],"range:":[859,867],"2.5-329)":[860],"101.9":[864],"(\u00b162.4;":[866],"2.5-441)":[868],"men.":[870,909],"deficiency":[873,895,1299,1349,1398],"(25OHD":[874,896],"[12]),":[878],"present":[880],"40%":[883,1302],"20%":[890],"men;":[893],"severe":[894],"<25":[897],"nmol/L;":[898],"[13])":[899],"identified":[901],"13.5%":[903],"5.9%":[907],"Among":[910],"enrolled":[916],"baseline,":[918,1450],"total":[920,950],"1904":[922],"completed":[924,959],"follow-up":[926,961],"assessment":[928,963],"1999":[930],"2001":[932],"included":[935,966],"(mean":[942],"[SD]":[943],"4.4":[945],"[1.1]":[946],"years),":[947],"whereas":[948,1284],"1675":[952],"(363M/":[953],"1039F,":[954],"65-99":[956],")":[958],"GDS":[962],"risk.":[972],"Association":[973,1212],"Significant":[980],"associations":[982,1436],"(p":[988,1002,1013],"trend":[990,1004,1015,1031,1429],"<.0001":[991,1019,1045],"women;":[993,1018,1044],".03":[994],"men),":[996,1047],"speed":[998,1058,1137],"<.0001,":[1005],"genders),":[1008],"<.0009":[1016],"men).":[1021],"After":[1022],"controlling":[1023,1275],"confounders":[1025],"covariates,":[1027],"significant":[1029,1195,1273,1289],"still":[1033],"genders":[1041],"(p=.0002":[1042],"(p=.004),":[1054],"(p=.0006)":[1059],"(p=.03)":[1063],"men,":[1065],"Table":[1069],"1a":[1070],"1b.":[1072],"concentrations":[1077,1153],"measures":[1080],"TCS,":[1084],"Figure":[1094],"1a,b,c,":[1095],"d":[1097],"respectively.":[1098],"decreased":[1107],"only":[1116,1229],"improvements":[1121,1196],"occurred":[1122],"20":[1124],"100":[1126,1145,1174,1188],"25OHD.":[1129],"but":[1132,1271],"not":[1133],"increased":[1138,1412],"improvement":[1150],"occurring":[1151],"ranging":[1154],"50":[1156],"approximately":[1158,1301],"75":[1159],"nmol/L.":[1160,1175],"improved":[1163],"continued":[1179],"increase":[1181],"genders.":[1192,1211],"No":[1193],"further":[1194],"these":[1198],"four":[1199],"seen":[1203],">100":[1207],"longitudinal":[1217],"risk":[1221,1355,1489],"adjusted":[1228,1364,1393],"score,":[1234],"who":[1236,1250,1326,1371,1407,1418,1446],"deficient":[1239,1280,1374,1421],"(<50":[1240],"nmol/l)":[1241],"(>50-<75)":[1244],"likely":[1247,1304],"than":[1248,1305,1405,1468],"those":[1249,1306,1370,1417,1469],"repleted":[1253],"scores":[1264],"(Table":[1265,1331,1389,1496],"2).":[1266],"attenuated":[1270],"remained":[1272],"after":[1274],"group":[1282],"only,":[1283,1369],"no":[1287,1478],"longer":[1288],"group.":[1294],"experience":[1310],"Restricting":[1321],"non-demented":[1328,1448],"3),":[1332],"even":[1342,1451],"evident.":[1344],"insufficiency":[1351],"higher":[1354],"4y.":[1360],"random-effects":[1362],"experienced":[1375],"about":[1381],"twice":[1382],"observed":[1384,1438,1470],"participant":[1386],"4).":[1390],"fully":[1392],"models,":[1394],"declined":[1399],"0.59":[1401],"sufficient.":[1410],"rate":[1413],"statistically":[1423],"significant,":[1424],"groups.":[1431],"same":[1433],"pattern":[1434],"when":[1439],"restricted":[1441],"though":[1452],"slightly":[1466],"all":[1472],"participants.":[1473],"At":[1474],"Cox":[1475],"analysis,":[1477],"4":[1494],"years":[1495],"5).":[1497],"CONCLUSION":[1498]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}