{"id":"https://openalex.org/W2276543293","doi":"https://doi.org/10.1016/s0160-3450(15)30013-1","title":"Genetically Engineered Vaccines","display_name":"Genetically Engineered Vaccines","publication_year":1995,"publication_date":"1995-12-01","ids":{"openalex":"https://openalex.org/W2276543293","doi":"https://doi.org/10.1016/s0160-3450(15)30013-1","mag":"2276543293","pmid":"https://pubmed.ncbi.nlm.nih.gov/8546075"},"language":"en","primary_location":{"id":"doi:10.1016/s0160-3450(15)30013-1","doi":"https://doi.org/10.1016/s0160-3450(15)30013-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0160-3450(15)30013-1","pdf_url":null,"source":{"id":"https://openalex.org/S2754106657","display_name":"American Pharmacy","issn_l":"0160-3450","issn":["0160-3450","2543-0912"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Pharmacy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103689052","display_name":"Jeffrey A. Hughes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey A. Hughes","raw_affiliation_strings":["College of Pharmacy, University of Florida, Gainesville, USA","College of Pharmacy, University of Florida, Gainesville"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, University of Florida, Gainesville, USA","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"College of Pharmacy, University of Florida, Gainesville","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054494090","display_name":"Gayle A. Brazeau","orcid":"https://orcid.org/0000-0002-4702-374X","observed_orcids":["https://orcid.org/0000-0002-4702-374X"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gayle A. Brazeau","raw_affiliation_strings":["College of Pharmacy, University of Florida, Gainesville"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, University of Florida, Gainesville","institution_ids":["https://openalex.org/I33213144"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I33213144"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.1609987,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"35","issue":"12","first_page":"9","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.20080000162124634,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.20080000162124634,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.12049999833106995,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.1145000010728836,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genetically-engineered-vaccines","display_name":"genetically engineered vaccines","score":0.9909999966621399},{"id":"https://openalex.org/keywords/recombinant-vaccine","display_name":"recombinant vaccine","score":0.8700000047683716},{"id":"https://openalex.org/keywords/vaccine-development","display_name":"vaccine development","score":0.4790000021457672},{"id":"https://openalex.org/keywords/genetic-engineering","display_name":"genetic engineering","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C3019111730","wikidata":"https://www.wikidata.org/wiki/Q159236","display_name":"Genetically engineered","level":3,"score":0.7838754057884216},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.46605122089385986},{"id":"https://openalex.org/C51456166","wikidata":"https://www.wikidata.org/wiki/Q182726","display_name":"Genetically modified organism","level":3,"score":0.44793450832366943},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32074692845344543},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3062206506729126},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30420154333114624},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18722277879714966},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06993234157562256}],"mesh":[{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D005818","descriptor_name":"Genetic Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014613","descriptor_name":"Vaccines, Attenuated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014614","descriptor_name":"Vaccines, Synthetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015164","descriptor_name":"Vaccines, Inactivated","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017325","descriptor_name":"Hepatitis B Vaccines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0160-3450(15)30013-1","doi":"https://doi.org/10.1016/s0160-3450(15)30013-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0160-3450(15)30013-1","pdf_url":null,"source":{"id":"https://openalex.org/S2754106657","display_name":"American Pharmacy","issn_l":"0160-3450","issn":["0160-3450","2543-0912"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Pharmacy","raw_type":"journal-article"},{"id":"pmid:8546075","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8546075","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American pharmacy","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4235509834","https://openalex.org/W4213125152","https://openalex.org/W2011607833","https://openalex.org/W2932604113","https://openalex.org/W2408687590","https://openalex.org/W830336535","https://openalex.org/W2416732764","https://openalex.org/W4210377526","https://openalex.org/W2404886875","https://openalex.org/W7028705277"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}