{"id":"https://openalex.org/W2276457729","doi":null,"title":"Myocardial injury and performance in hypoxaemic neonates: Effects of oxygen and carbon dioxide during reoxygenation : An experimental study in newborn pigs","display_name":"Myocardial injury and performance in hypoxaemic neonates: Effects of oxygen and carbon dioxide during reoxygenation : An experimental study in newborn pigs","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2276457729","mag":"2276457729"},"language":"en","primary_location":{"id":"pmh:oai:www.duo.uio.no:10852/28072","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/28072","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10852/28072","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009288174","display_name":"Wenche Bakken B\u00f8rke","orcid":"https://orcid.org/0000-0003-3565-3944","observed_orcids":["https://orcid.org/0000-0003-3565-3944"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Wenche Bakken B\u00f8rke","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3565-3944","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5009288174"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.5713000297546387,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.5713000297546387,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.2289000004529953,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.11400000005960464,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myocardial-injury","display_name":"myocardial injury","score":0.8640000224113464},{"id":"https://openalex.org/keywords/perinatal-asphyxia","display_name":"perinatal asphyxia","score":0.8939999938011169},{"id":"https://openalex.org/keywords/hypoxemia","display_name":"hypoxemia","score":0.8209999799728394},{"id":"https://openalex.org/keywords/hypercapnia","display_name":"hypercapnia","score":0.7580000162124634},{"id":"https://openalex.org/keywords/reoxygenation","display_name":"reoxygenation","score":0.871999979019165},{"id":"https://openalex.org/keywords/carbon-dioxide","display_name":"carbon dioxide","score":0.5950000286102295},{"id":"https://openalex.org/keywords/oxygen-therapy","display_name":"oxygen therapy","score":0.6100000143051147},{"id":"https://openalex.org/keywords/myocardial-function","display_name":"myocardial function","score":0.48399999737739563},{"id":"https://openalex.org/keywords/left-ventricular-failure","display_name":"left ventricular failure","score":0.6389999985694885},{"id":"https://openalex.org/keywords/pulmonary-hypertension-of-the-newborn","display_name":"neonatal pulmonary hypertension","score":0.7350000143051147},{"id":"https://openalex.org/keywords/tricuspid-regurgitation","display_name":"tricuspid regurgitation","score":0.7950000166893005},{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"myocardial ischemia","score":0.6940000057220459},{"id":"https://openalex.org/keywords/neonatal-piglets","display_name":"newborn piglets","score":0.5130000114440918},{"id":"https://openalex.org/keywords/cardiogenic-shock","display_name":"cardiogenic shock","score":0.5370000004768372},{"id":"https://openalex.org/keywords/hypoxic-ischemic-encephalopathy","display_name":"hypoxic-ischemic encephalopathy","score":0.7110000252723694}],"concepts":[{"id":"https://openalex.org/C530467964","wikidata":"https://www.wikidata.org/wiki/Q1997","display_name":"Carbon dioxide","level":2,"score":0.7365953326225281},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.5622581839561462},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5422123670578003},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49866175651550293},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18882891535758972},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.1863313615322113},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:www.duo.uio.no:10852/28072","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/28072","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2276457729","doi":null,"is_oa":false,"landing_page_url":"https://www.duo.uio.no/bitstream/handle/10852/28072/Medisinavh_Borke_DUO.pdf?sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:www.duo.uio.no:10852/28072","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/28072","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":189,"referenced_works":["https://openalex.org/W648147","https://openalex.org/W34655061","https://openalex.org/W114939658","https://openalex.org/W121205463","https://openalex.org/W122703471","https://openalex.org/W142345870","https://openalex.org/W187079842","https://openalex.org/W201062702","https://openalex.org/W204075985","https://openalex.org/W823826608","https://openalex.org/W1529433619","https://openalex.org/W1539147816","https://openalex.org/W1596522113","https://openalex.org/W1599431022","https://openalex.org/W1602349497","https://openalex.org/W1837514398","https://openalex.org/W1842923723","https://openalex.org/W1846208898","https://openalex.org/W1875553690","https://openalex.org/W1907378296","https://openalex.org/W1946030595","https://openalex.org/W1961656981","https://openalex.org/W1964994147","https://openalex.org/W1966034041","https://openalex.org/W1967890020","https://openalex.org/W1971653265","https://openalex.org/W1972674620","https://openalex.org/W1976733887","https://openalex.org/W1976773462","https://openalex.org/W1978632222","https://openalex.org/W1979500175","https://openalex.org/W1981507750","https://openalex.org/W1981682680","https://openalex.org/W1982985770","https://openalex.org/W1983868056","https://openalex.org/W1985220884","https://openalex.org/W1986569614","https://openalex.org/W1986768111","https://openalex.org/W1987364747","https://openalex.org/W1988297017","https://openalex.org/W1988374241","https://openalex.org/W1989127685","https://openalex.org/W1994329246","https://openalex.org/W1995221756","https://openalex.org/W1995304776","https://openalex.org/W1997383859","https://openalex.org/W1997557771","https://openalex.org/W1998305917","https://openalex.org/W1999805650","https://openalex.org/W2000016000","https://openalex.org/W2003479111","https://openalex.org/W2004047053","https://openalex.org/W2004398448","https://openalex.org/W2004855759","https://openalex.org/W2006187084","https://openalex.org/W2007464754","https://openalex.org/W2007899104","https://openalex.org/W2008984189","https://openalex.org/W2009248023","https://openalex.org/W2010913288","https://openalex.org/W2011556631","https://openalex.org/W2014237099","https://openalex.org/W2014945678","https://openalex.org/W2015098893","https://openalex.org/W2016249305","https://openalex.org/W2017055786","https://openalex.org/W2017886904","https://openalex.org/W2019794653","https://openalex.org/W2020172502","https://openalex.org/W2020326559","https://openalex.org/W2020840142","https://openalex.org/W2022479328","https://openalex.org/W2023023486","https://openalex.org/W2023087153","https://openalex.org/W2023484216","https://openalex.org/W2023861671","https://openalex.org/W2024560631","https://openalex.org/W2026392916","https://openalex.org/W2027236019","https://openalex.org/W2030585152","https://openalex.org/W2033301420","https://openalex.org/W2038633055","https://openalex.org/W2039323243","https://openalex.org/W2041077342","https://openalex.org/W2041888873","https://openalex.org/W2043445024","https://openalex.org/W2046202334","https://openalex.org/W2048237036","https://openalex.org/W2048749182","https://openalex.org/W2049348339","https://openalex.org/W2050524977","https://openalex.org/W2050724872","https://openalex.org/W2051000112","https://openalex.org/W2051245896","https://openalex.org/W2051353161","https://openalex.org/W2054003361","https://openalex.org/W2054878754","https://openalex.org/W2056198629","https://openalex.org/W2056621596","https://openalex.org/W2058523630","https://openalex.org/W2059215187","https://openalex.org/W2063363164","https://openalex.org/W2063377279","https://openalex.org/W2064190260","https://openalex.org/W2064622835","https://openalex.org/W2066689305","https://openalex.org/W2067537480","https://openalex.org/W2068486450","https://openalex.org/W2069270929","https://openalex.org/W2072348601","https://openalex.org/W2073542283","https://openalex.org/W2074963734","https://openalex.org/W2080351010","https://openalex.org/W2081120501","https://openalex.org/W2081587623","https://openalex.org/W2082076982","https://openalex.org/W2083287402","https://openalex.org/W2084216570","https://openalex.org/W2084305984","https://openalex.org/W2085476682","https://openalex.org/W2086322772","https://openalex.org/W2089678610","https://openalex.org/W2089925749","https://openalex.org/W2090338393","https://openalex.org/W2091601208","https://openalex.org/W2092377409","https://openalex.org/W2092716848","https://openalex.org/W2093257539","https://openalex.org/W2093322092","https://openalex.org/W2099256958","https://openalex.org/W2100972081","https://openalex.org/W2108256295","https://openalex.org/W2109658199","https://openalex.org/W2109907166","https://openalex.org/W2110565948","https://openalex.org/W2114152651","https://openalex.org/W2115946769","https://openalex.org/W2119596286","https://openalex.org/W2120327065","https://openalex.org/W2120831964","https://openalex.org/W2121189945","https://openalex.org/W2122810132","https://openalex.org/W2122892850","https://openalex.org/W2124450086","https://openalex.org/W2126910504","https://openalex.org/W2131364104","https://openalex.org/W2131576310","https://openalex.org/W2135610021","https://openalex.org/W2136387632","https://openalex.org/W2137474478","https://openalex.org/W2137497846","https://openalex.org/W2138303189","https://openalex.org/W2139834186","https://openalex.org/W2140808477","https://openalex.org/W2141543212","https://openalex.org/W2145543131","https://openalex.org/W2147993424","https://openalex.org/W2149574331","https://openalex.org/W2150951327","https://openalex.org/W2152395959","https://openalex.org/W2154297318","https://openalex.org/W2154401382","https://openalex.org/W2155579919","https://openalex.org/W2157291239","https://openalex.org/W2157534984","https://openalex.org/W2160030499","https://openalex.org/W2162713311","https://openalex.org/W2164721721","https://openalex.org/W2165378923","https://openalex.org/W2167318964","https://openalex.org/W2176503073","https://openalex.org/W2218524791","https://openalex.org/W2239835326","https://openalex.org/W2274392996","https://openalex.org/W2292097009","https://openalex.org/W2322613273","https://openalex.org/W2330614853","https://openalex.org/W2340701771","https://openalex.org/W2395020274","https://openalex.org/W2399213352","https://openalex.org/W2410848066","https://openalex.org/W2414232020","https://openalex.org/W2417443733","https://openalex.org/W2422242303","https://openalex.org/W2432571697","https://openalex.org/W2472479967","https://openalex.org/W2612240048","https://openalex.org/W2988622013","https://openalex.org/W4206452565"],"related_works":["https://openalex.org/W1977091412","https://openalex.org/W2889515859","https://openalex.org/W2745826736","https://openalex.org/W3030539912","https://openalex.org/W2036558005","https://openalex.org/W7197810205","https://openalex.org/W2576433597","https://openalex.org/W2794340918","https://openalex.org/W3094971685","https://openalex.org/W2909229303"],"abstract_inverted_index":{"Definition":[0],"of":[1,10,18,50,67,85,133,166,180,193,224,230,236,242,311,322,334],"asphyxia.\\nAsphyxia":[2],"is":[3,14,28,45,71,78,125,252,268,281,316,339,356,365],"a":[4,41,48,55,79,83,130,164,191],"Greek":[5],"term":[6,186],"and":[7,52,58,76,98,128,200,202,249,256,279,299,332,344],"means":[8],"loss":[9],"pulse":[11],"(1).":[12,61],"There":[13],"no":[15],"clear":[16],"definition":[17],"the":[19,38,43,65,108,176,212,225,231,237,243,253,258,273,285,314,323,335,345],"term,":[20],"though":[21],"perinatal":[22,68,86,113,307],"asphyxia":[23,26,69,154,216,308,312,350],"or":[24,33,144,320,329],"birth":[25],"often":[27,126],"defined":[29],"as":[30,263],"impaired":[31],"placental-":[32],"pulmonary":[34,201,240,245],"oxygen":[35],"delivery":[36],"to":[37,120,135,146,153,270,341,354,367,373],"neonate.":[39],"As":[40],"consequence":[42],"neonate":[44],"going":[46],"through":[47],"period":[49],"hypoxaemia":[51],"hypercapnia":[53],"with":[54,169,190],"subsequent":[56,119,152],"respiratory":[57],"metabolic":[59],"acidosis":[60],"In":[62,287],"clinical":[63,139,265,346],"work,":[64],"diagnosis":[66,109],"predominantly":[70],"based":[72],"on":[73],"its":[74,342],"consequences,":[75],"there":[77,280],"general":[80],"agreement":[81],"that":[82,272],"combination":[84],"stress":[87],"(i.e.":[88,101],"fetal":[89,328],"bradycardia,":[90],"acidosis,":[91],"low":[92],"Apgar":[93],"scores),":[94],"multiple":[95],"organ":[96],"affection":[97],"neurological":[99],"symptoms":[100],"hypoxic":[102],"ischemic":[103,295],"encephalopathy)":[104],"are":[105],"required":[106],"for":[107],"(2).\\nCardiac":[110],"abnormalities":[111,214,260],"in":[112,158,217,284,313,348,358],"asphyxia.":[114,121],"\\nMyocardial":[115,150],"performance":[116],"may":[117,275,351],"vary":[118],"The":[122,138,161],"cardiac":[123,213,259],"dysfunction":[124],"underdiagnosed":[127],"requires":[129],"high":[131],"index":[132],"suspicion":[134],"detect":[136],"(3;4).":[137],"picture":[140,347],"varies":[141],"from":[142],"brady-":[143],"tachycardia":[145],"cardiogenic":[147],"shock":[148],"(1;5).":[149],"failure":[151,174,196],"was":[155],"first":[156,177],"reported":[157,189],"1961":[159],"(6).":[160],"authors":[162],"described":[163,262],"group":[165],"asphyxiated":[167,289],"neonates":[168,290,370],"left":[170,302],"ventricular":[171,303],"(LV)":[172,304],"heart":[173,361,376],"within":[175],"24":[178],"hours":[179],"life.":[181],"A":[182],"decade":[183],"later":[184],"three":[185],"infants":[187],"were":[188,261],"syndrome":[192],"acute":[194],"LV":[195],"accompanied":[197],"by":[198,371],"cyanosis":[199],"systemic":[203],"venous":[204],"congestion":[205],"(7).":[206],"Rowe":[207],"et":[208],"al.":[209],"(8)":[210],"classified":[211],"following":[215],"1978,":[218],"broadly":[219],"as:\\n1)":[220],"Transient":[221,227,233],"myocardial":[222],"ischaemia":[223],"newborn\\n2)":[226],"mitral":[228],"regurgitation":[229,235,251],"newborn\\n3)":[232],"tricuspid":[234,250],"newborn\\n4)":[238],"Persistent":[239],"hypertension":[241],"newborn\\nIncreased":[244],"artery":[246],"pressure":[247],"(PAP)":[248],"most":[254],"common,":[255],"although":[257],"separate":[264],"entities,":[266],"it":[267,364],"important":[269],"understand":[271],"distinction":[274],"not":[276],"be":[277],"clear,":[278],"much":[282],"overlap":[283],"pathogenesis.":[286],"severely":[288],"post-mortem":[291],"autopsies":[292],"have":[293],"showed":[294],"papillary":[296],"muscle":[297],"necrosis":[298,305],"diffuse":[300],"subendocardial":[301],"secondary\\nto":[306],"(9;10).\\nAetiology\\nThe":[309],"aetiology":[310],"newborn":[315],"multifactorial,":[317],"including":[318],"abruption":[319],"infarction":[321],"placenta,":[324],"excessive":[325],"uterine":[326],"contraction,":[327],"maternal":[330],"bleeding,":[331],"compression":[333],"umbilical":[336],"cord.":[337],"Infection":[338],"contributing":[340],"severity,":[343],"severe":[349,359],"present":[352],"similar":[353],"what":[355],"seen":[357],"congenital":[360,375],"disease,":[362],"thus":[363],"mandatory":[366],"evaluate":[368],"these":[369],"echocardiography":[372],"exclude":[374],"disease.":[377]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
