{"id":"https://openalex.org/W2275448331","doi":"https://doi.org/10.1152/ajpregu.1991.261.2.r339","title":"Influence of fatty acid oxidation in lateral hypothalamus on food intake and body composition","display_name":"Influence of fatty acid oxidation in lateral hypothalamus on food intake and body composition","publication_year":1991,"publication_date":"1991-08-01","ids":{"openalex":"https://openalex.org/W2275448331","doi":"https://doi.org/10.1152/ajpregu.1991.261.2.r339","mag":"2275448331","pmid":"https://pubmed.ncbi.nlm.nih.gov/1877693"},"language":"en","primary_location":{"id":"doi:10.1152/ajpregu.1991.261.2.r339","doi":"https://doi.org/10.1152/ajpregu.1991.261.2.r339","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.1991.261.2.r339","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035932972","display_name":"Joseph Lee Beverly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. L. Beverly","raw_affiliation_strings":["Department of Foods and Nutrition, University of Georgia, Athens30602"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Foods and Nutrition, University of Georgia, Athens30602","institution_ids":["https://openalex.org/I165733156"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004945082","display_name":"Roy Joseph Martin","orcid":"https://orcid.org/0000-0002-0253-7982","observed_orcids":["https://orcid.org/0000-0002-0253-7982"]},"institutions":[{"id":"https://openalex.org/I165733156","display_name":"University of Georgia","ror":"https://ror.org/00te3t702","country_code":"US","type":"education","lineage":["https://openalex.org/I165733156"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. J. Martin","raw_affiliation_strings":["Department of Foods and Nutrition, University of Georgia, Athens30602"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Foods and Nutrition, University of Georgia, Athens30602","institution_ids":["https://openalex.org/I165733156"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I165733156"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.14959505,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"261","issue":"2","first_page":"R339","last_page":"R343"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.9399999976158142},{"id":"https://openalex.org/keywords/ventrolateral-hypothalamus","display_name":"ventrolateral hypothalamus","score":0.9589999914169312},{"id":"https://openalex.org/keywords/food-consumption","display_name":"dietary intake","score":0.8550000190734863},{"id":"https://openalex.org/keywords/body-composition","display_name":"body composition","score":0.9409999847412109},{"id":"https://openalex.org/keywords/energy-balance","display_name":"energy balance","score":0.9279999732971191},{"id":"https://openalex.org/keywords/4-pentenoic-acid","display_name":"4-pentenoic acid","score":0.9369999766349792},{"id":"https://openalex.org/keywords/l-carnitine","display_name":"L-carnitine","score":0.9929999709129333},{"id":"https://openalex.org/keywords/overfeeding","display_name":"overfeeding","score":0.7950000166893005},{"id":"https://openalex.org/keywords/dietary-restriction","display_name":"dietary restriction","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.753989040851593},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7466202974319458},{"id":"https://openalex.org/C82714985","wikidata":"https://www.wikidata.org/wiki/Q306213","display_name":"Beta oxidation","level":3,"score":0.6888362765312195},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.6308225989341736},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.6208701133728027},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.473174124956131},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4133240580558777},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3172909617424011},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2502261996269226},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1516455113887787}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002331","descriptor_name":"Carnitine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004435","descriptor_name":"Eating","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005229","descriptor_name":"Fatty Acids, Monounsaturated","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007026","descriptor_name":"Hypothalamic Area, Lateral","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010168","descriptor_name":"Palmitates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpregu.1991.261.2.r339","doi":"https://doi.org/10.1152/ajpregu.1991.261.2.r339","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.1991.261.2.r339","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},{"id":"pmid:1877693","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1877693","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Affordable and clean energy","score":0.44999998807907104,"id":"https://metadata.un.org/sdg/7"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2035298488","https://openalex.org/W1939273416","https://openalex.org/W2055804542","https://openalex.org/W1949697803","https://openalex.org/W2071141358","https://openalex.org/W121678769","https://openalex.org/W2021910273","https://openalex.org/W2040297738","https://openalex.org/W7098065951","https://openalex.org/W1994022217"],"abstract_inverted_index":{"This":[0],"study":[1],"tested":[2],"the":[3,6,13,36,48,70,107,123,149,156],"concept":[4],"that":[5,148],"level":[7,150],"of":[8,93,102,117,135,144,151],"fatty":[9,103,119,140,152],"acid":[10,32,54,66,104,120,153],"oxidation":[11,33,67,105,121,154],"in":[12,27,35,69,106,122,155,164],"ventrolateral":[14],"hypothalamus":[15,109],"(VLH)":[16],"reflects":[17],"peripheral":[18,168],"energy":[19,28],"stores":[20],"and":[21,85,110,138],"elicits":[22],"compensatory":[23],"responses":[24],"to":[25,74,160],"changes":[26,163],"balance":[29],"status.":[30],"Fatty":[31,65],"rates":[34,68,101],"VLH":[37,49,71,124,157],"were":[38,72,99,113],"chronically":[39],"altered":[40,73],"over":[41],"a":[42,75],"14-day":[43],"period":[44],"by":[45,79,83,90],"infusing":[46],"into":[47],"either":[50],"0.1":[51],"mM":[52,60],"4-pentenoic":[53],"(4-PA;":[55],"5":[56],"ng/h)":[57],"or":[58,132,167],"1.0":[59],"L-carnitine":[61],"(L-Carn;":[62],"98":[63],"ng/h).":[64],"similar":[76],"extent":[77],"as":[78],"overfeeding":[80],"(reduced":[81],"37%":[82],"4-PA)":[84],"dietary":[86],"restriction":[87],"(increased":[88],"28%":[89],"L-Carn).":[91],"Diffusion":[92],"infusates":[94],"was":[95],"limited,":[96],"since":[97],"there":[98],"normal":[100],"ventromedial":[108],"cortex.":[111],"There":[112],"no":[114],"significant":[115],"effects":[116],"altering":[118],"on":[125],"food":[126,165],"intake,":[127],"body":[128,130],"weight,":[129],"composition,":[131],"serum":[133],"levels":[134],"glucose,":[136],"insulin,":[137],"free":[139],"acids.":[141],"The":[142],"results":[143],"this":[145],"experiment":[146],"indicate":[147],"is":[158],"unlikely":[159],"independently":[161],"elicit":[162],"intake":[166],"metabolism.":[169]},"counts_by_year":[{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}