{"id":"https://openalex.org/W2275196604","doi":null,"title":"Trehalase inhibition in Aedes aegypti","display_name":"Trehalase inhibition in Aedes aegypti","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2275196604","mag":"2275196604"},"language":"en","primary_location":{"id":"pmh:oai:summit.sfu.ca:node-9272","doi":null,"is_oa":true,"landing_page_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","pdf_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","source":{"id":"https://openalex.org/S4306400490","display_name":"Summit (Simon Fraser University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I18014758","host_organization_name":"Simon Fraser University","host_organization_lineage":["https://openalex.org/I18014758"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017029218","display_name":"C. Logan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"C. Logan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5017029218"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.5756999850273132,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.5756999850273132,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11065","display_name":"Insect Pest Control Strategies","score":0.10379999876022339,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12043","display_name":"Insect behavior and control techniques","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aedes-aegypti","display_name":"Aedes aegypti","score":0.9580000042915344},{"id":"https://openalex.org/keywords/trehalase-inhibition","display_name":"trehalase inhibition","score":0.9399999976158142},{"id":"https://openalex.org/keywords/trehalose","display_name":"trehalose","score":0.8379999995231628},{"id":"https://openalex.org/keywords/carbohydrate-metabolism","display_name":"carbohydrate metabolism","score":0.8560000061988831},{"id":"https://openalex.org/keywords/plagiorchis-elegans","display_name":"Plagiorchis elegans","score":0.9589999914169312},{"id":"https://openalex.org/keywords/trematode-infection","display_name":"trematode infection","score":0.777999997138977},{"id":"https://openalex.org/keywords/oviposition-deterrence","display_name":"oviposition deterrence","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hemolymph-biochemistry","display_name":"hemolymph biochemistry","score":0.7639999985694885},{"id":"https://openalex.org/keywords/insect-pest-management","display_name":"insect pest management","score":0.7590000033378601},{"id":"https://openalex.org/keywords/dengue-vector","display_name":"dengue vector","score":0.8930000066757202}],"concepts":[{"id":"https://openalex.org/C2779315325","wikidata":"https://www.wikidata.org/wiki/Q410630","display_name":"Trehalase","level":3,"score":0.9016928672790527},{"id":"https://openalex.org/C2777775583","wikidata":"https://www.wikidata.org/wiki/Q1148004","display_name":"Aedes aegypti","level":3,"score":0.8833448886871338},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4441484808921814},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.3553389310836792},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.27754658460617065},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09688892960548401},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08487212657928467},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.0710090696811676}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:summit.sfu.ca:node-9272","doi":null,"is_oa":true,"landing_page_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","pdf_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","source":{"id":"https://openalex.org/S4306400490","display_name":"Summit (Simon Fraser University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I18014758","host_organization_name":"Simon Fraser University","host_organization_lineage":["https://openalex.org/I18014758"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:summit.sfu.ca:9272","doi":null,"is_oa":false,"landing_page_url":"http://summit.sfu.ca/item/9272","pdf_url":null,"source":{"id":"https://openalex.org/S4306400490","display_name":"Summit (Simon Fraser University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I18014758","host_organization_name":"Simon Fraser University","host_organization_lineage":["https://openalex.org/I18014758"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2275196604","doi":null,"is_oa":false,"landing_page_url":"https://summit.sfu.ca/system/files/iritems1/9272/etd4270.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:summit.sfu.ca:node-9272","doi":null,"is_oa":true,"landing_page_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","pdf_url":"https://summit.sfu.ca/_flysystem/fedora/sfu_migrate/9272/etd4270.pdf","source":{"id":"https://openalex.org/S4306400490","display_name":"Summit (Simon Fraser University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I18014758","host_organization_name":"Simon Fraser University","host_organization_lineage":["https://openalex.org/I18014758"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2275196604.pdf","grobid_xml":"https://content.openalex.org/works/W2275196604.grobid-xml"},"referenced_works_count":82,"referenced_works":["https://openalex.org/W13766186","https://openalex.org/W17326370","https://openalex.org/W17339332","https://openalex.org/W137883589","https://openalex.org/W163546078","https://openalex.org/W185601674","https://openalex.org/W570982476","https://openalex.org/W605120477","https://openalex.org/W1215684641","https://openalex.org/W1491842509","https://openalex.org/W1512613013","https://openalex.org/W1531276308","https://openalex.org/W1532082124","https://openalex.org/W1779665718","https://openalex.org/W1841057661","https://openalex.org/W1963749283","https://openalex.org/W1963923091","https://openalex.org/W1966015128","https://openalex.org/W1971058116","https://openalex.org/W1972024357","https://openalex.org/W1976887204","https://openalex.org/W1981802815","https://openalex.org/W1999400395","https://openalex.org/W2003167401","https://openalex.org/W2003918610","https://openalex.org/W2010696972","https://openalex.org/W2014997440","https://openalex.org/W2037268688","https://openalex.org/W2043806757","https://openalex.org/W2044016720","https://openalex.org/W2045211613","https://openalex.org/W2048390563","https://openalex.org/W2061281790","https://openalex.org/W2061353988","https://openalex.org/W2061373995","https://openalex.org/W2063812037","https://openalex.org/W2071464148","https://openalex.org/W2073250359","https://openalex.org/W2074109610","https://openalex.org/W2095348431","https://openalex.org/W2099489869","https://openalex.org/W2108865450","https://openalex.org/W2113364572","https://openalex.org/W2113489177","https://openalex.org/W2118707645","https://openalex.org/W2121867223","https://openalex.org/W2124501455","https://openalex.org/W2124962442","https://openalex.org/W2127298038","https://openalex.org/W2128635872","https://openalex.org/W2129010749","https://openalex.org/W2131931165","https://openalex.org/W2140836172","https://openalex.org/W2142733283","https://openalex.org/W2149235043","https://openalex.org/W2150639539","https://openalex.org/W2155110504","https://openalex.org/W2156350829","https://openalex.org/W2157938678","https://openalex.org/W2166998765","https://openalex.org/W2169624508","https://openalex.org/W2173812327","https://openalex.org/W2270042755","https://openalex.org/W2274098398","https://openalex.org/W2313559456","https://openalex.org/W2317777482","https://openalex.org/W2319054860","https://openalex.org/W2320328878","https://openalex.org/W2324210353","https://openalex.org/W2324436739","https://openalex.org/W2325871900","https://openalex.org/W2329922482","https://openalex.org/W2332412655","https://openalex.org/W2333861622","https://openalex.org/W2335079800","https://openalex.org/W2397834868","https://openalex.org/W2410137647","https://openalex.org/W2412467419","https://openalex.org/W2417460907","https://openalex.org/W2500749548","https://openalex.org/W2504591527","https://openalex.org/W2982317197"],"related_works":["https://openalex.org/W3002910539","https://openalex.org/W7065251713","https://openalex.org/W2062174388","https://openalex.org/W2314438891","https://openalex.org/W2124962442","https://openalex.org/W2159740972","https://openalex.org/W4409699339","https://openalex.org/W570982476","https://openalex.org/W4319599666","https://openalex.org/W1894278903"],"abstract_inverted_index":{"Aedes":[0],"aegypti":[1,19],"is":[2,134],"the":[3,9,22,35,42,51,114],"principal":[4],"vector":[5],"of":[6,17,30,37,44,54,78,117,126],"Dengue":[7],"virus,":[8],"most":[10],"important":[11],"mosquito-borne":[12],"viral":[13],"disease":[14],"affecting":[15],"humans.Infection":[16],"Ae.":[18],"larvae":[20,81,118],"by":[21,33,108],"trematode":[23],"Plagiorchis":[24],"elegans":[25,110],"leads":[26],"to":[27,39,75],"a":[28,55],"disruption":[29],"carbohydrate":[31,123],"metabolism":[32],"preventing":[34],"conversion":[36],"trehalose":[38,84],"glucose,":[40],"and":[41,89],"production":[43],"an":[45],"oviposition":[46],"deterrent":[47],"compound.This":[48],"thesis":[49],"examines":[50],"dose-dependent":[52],"effects":[53],"trehalase":[56,128],"inhibitor,":[57],"Validoxylamine":[58],"A":[59],"(VAA),":[60],"on":[61,67],"Ae.aegypti.VAA":[62],"had":[63,82],"no":[64],"noticeable":[65],"effect":[66],"larval":[68],"mortality":[69],"but":[70,120],"emerging":[71],"adults":[72],"were":[73],"unable":[74],"fly.The":[76],"hemolymph":[77],"VAA":[79,101],"exposed":[80],"increased":[83,90],"levels,":[85],"reduced":[86],"glucose":[87],"concentrations,":[88],"lipid":[91],"content":[92],"compared":[93],"with":[94],"controls.In":[95],"addition,":[96],"adult":[97],"mosquitoes":[98],"that":[99],"ingested":[100],"laid":[102],"significantly":[103],"fewer":[104],"eggs":[105],"than":[106],"controls.Parasitism":[107],"P.":[109],"did":[111],"not":[112],"reduce":[113],"energy":[115],"reserves":[116],"significantly,":[119],"influenced":[121],"mosquito":[122],"biochemistry.The":[124],"concept":[125],"utilizing":[127],"inhibitors":[129],"for":[130],"insect":[131],"pest":[132],"management":[133],"discussed.":[135]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}