{"id":"https://openalex.org/W2275145293","doi":"https://doi.org/10.1074/jbc.m115.655654","title":"Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family","display_name":"Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family","publication_year":2015,"publication_date":"2015-06-24","ids":{"openalex":"https://openalex.org/W2275145293","doi":"https://doi.org/10.1074/jbc.m115.655654","mag":"2275145293","pmid":"https://pubmed.ncbi.nlm.nih.gov/26105055","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4528126"},"language":"en","primary_location":{"id":"doi:10.1074/jbc.m115.655654","doi":"https://doi.org/10.1074/jbc.m115.655654","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m115.655654","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1074/jbc.m115.655654","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039843568","display_name":"Rike Diderrich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rike Diderrich","raw_affiliation_strings":["From the Departments of Genetics and","Departments of Genetics, Philipps-Universit\u00e4t, 35043 Marburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Genetics and","institution_ids":[]},{"raw_affiliation_string":"Departments of Genetics, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067329860","display_name":"Michael Andreas Kock","orcid":"https://orcid.org/0000-0002-5355-4475","observed_orcids":["https://orcid.org/0000-0002-5355-4475"]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael Kock","raw_affiliation_strings":["Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]},{"raw_affiliation_string":"Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004960223","display_name":"Manuel Maestre\u2010Reyna","orcid":"https://orcid.org/0000-0002-9566-7216","observed_orcids":["https://orcid.org/0000-0002-9566-7216"]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Manuel Maestre-Reyna","raw_affiliation_strings":["Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]},{"raw_affiliation_string":"Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075340823","display_name":"Petra Keller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210100731","display_name":"Fraunhofer Institute for Interfacial Engineering and Biotechnology","ror":"https://ror.org/0131dra29","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210100731","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Petra Keller","raw_affiliation_strings":["the Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany, and","Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany, and","institution_ids":["https://openalex.org/I4210100731"]},{"raw_affiliation_string":"Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany","institution_ids":["https://openalex.org/I4210100731"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054621120","display_name":"H. Steuber","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Holger Steuber","raw_affiliation_strings":["Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]},{"raw_affiliation_string":"Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083761133","display_name":"Steffen Rupp","orcid":"https://orcid.org/0000-0002-4162-2274","observed_orcids":["https://orcid.org/0000-0002-4162-2274"]},"institutions":[{"id":"https://openalex.org/I100066346","display_name":"University of Stuttgart","ror":"https://ror.org/04vnq7t77","country_code":"DE","type":"education","lineage":["https://openalex.org/I100066346"]},{"id":"https://openalex.org/I4210100731","display_name":"Fraunhofer Institute for Interfacial Engineering and Biotechnology","ror":"https://ror.org/0131dra29","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210100731","https://openalex.org/I4923324"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Rupp","raw_affiliation_strings":["the Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany, and the Institut f\u00fcr Grenzfl\u00e4chenverfahrenstechnik und Plasmatechnologie, Universit\u00e4t Stuttgart, 70569 Stuttgart, Germany","Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany","Institut f\u00fcr Grenzfl\u00e4chenverfahrenstechnik und Plasmatechnologie, Universit\u00e4t Stuttgart, 70569 Stuttgart, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany, and the Institut f\u00fcr Grenzfl\u00e4chenverfahrenstechnik und Plasmatechnologie, Universit\u00e4t Stuttgart, 70569 Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346","https://openalex.org/I4210100731"]},{"raw_affiliation_string":"Fraunhofer-Institut f\u00fcr Grenzfl\u00e4chen und Bioverfahrenstechnik, 70569 Stuttgart, Germany","institution_ids":["https://openalex.org/I4210100731"]},{"raw_affiliation_string":"Institut f\u00fcr Grenzfl\u00e4chenverfahrenstechnik und Plasmatechnologie, Universit\u00e4t Stuttgart, 70569 Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033695434","display_name":"Lars\u2010Oliver Essen","orcid":"https://orcid.org/0000-0003-4272-4026","observed_orcids":["https://orcid.org/0000-0003-4272-4026"]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Lars-Oliver Essen","raw_affiliation_strings":["Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany, essen@chemie.uni-marburg.de","Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany, essen@chemie.uni-marburg.de","institution_ids":["https://openalex.org/I161103922"]},{"raw_affiliation_string":"Departments of Biochemistry, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079464088","display_name":"Hans\u2010Ulrich M\u00f6sch","orcid":"https://orcid.org/0000-0002-4660-6070","observed_orcids":["https://orcid.org/0000-0002-4660-6070"]},"institutions":[{"id":"https://openalex.org/I161103922","display_name":"Philipps University of Marburg","ror":"https://ror.org/01rdrb571","country_code":"DE","type":"education","lineage":["https://openalex.org/I161103922"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Hans-Ulrich M\u00f6sch","raw_affiliation_strings":["From the Departments of Genetics and moesch@staff.uni-marburg.de","Departments of Genetics, Philipps-Universit\u00e4t, 35043 Marburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Departments of Genetics and moesch@staff.uni-marburg.de","institution_ids":["https://openalex.org/I161103922"]},{"raw_affiliation_string":"Departments of Genetics, Philipps-Universit\u00e4t, 35043 Marburg, Germany","institution_ids":["https://openalex.org/I161103922"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033695434","https://openalex.org/A5079464088"],"corresponding_institution_ids":["https://openalex.org/I161103922"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":1.6152,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.83754225,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"290","issue":"32","first_page":"19597","last_page":"19613"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.4099000096321106,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.4099000096321106,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.39480000734329224,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.07400000095367432,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candida-glabrata","display_name":"Candida glabrata","score":1.0},{"id":"https://openalex.org/keywords/cell-wall-proteins","display_name":"cell wall proteins","score":0.5260000228881836},{"id":"https://openalex.org/keywords/host-colonization","display_name":"host colonization","score":0.531000018119812},{"id":"https://openalex.org/keywords/epithelial-cell-adhesion","display_name":"epithelial cell adhesion","score":0.7860000133514404},{"id":"https://openalex.org/keywords/binding-pocket","display_name":"binding pocket","score":0.7839999794960022},{"id":"https://openalex.org/keywords/functional-diversity","display_name":"functional diversity","score":0.6349999904632568},{"id":"https://openalex.org/keywords/paralogs","display_name":"paralogs","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C179470777","wikidata":"https://www.wikidata.org/wiki/Q356661","display_name":"Bacterial adhesin","level":4,"score":0.8832994103431702},{"id":"https://openalex.org/C2780670043","wikidata":"https://www.wikidata.org/wiki/Q139137","display_name":"Candida glabrata","level":3,"score":0.7960340976715088},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7548210620880127},{"id":"https://openalex.org/C2780758401","wikidata":"https://www.wikidata.org/wiki/Q408693","display_name":"Lectin","level":2,"score":0.48536932468414307},{"id":"https://openalex.org/C2910135453","wikidata":"https://www.wikidata.org/wiki/Q3122802","display_name":"Fungal protein","level":4,"score":0.4538508653640747},{"id":"https://openalex.org/C2776460866","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogen","level":2,"score":0.45321884751319885},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.45103487372398376},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.44893205165863037},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.44854068756103516},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.44751641154289246},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.41174134612083435},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.31113922595977783},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2898207902908325},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.24238213896751404},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2364075779914856},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.20823001861572266},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.1466393768787384}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005656","descriptor_name":"Fungal Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011134","descriptor_name":"Polysaccharides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D041221","descriptor_name":"Candida glabrata","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054730","descriptor_name":"Protein Interaction Domains and Motifs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1074/jbc.m115.655654","doi":"https://doi.org/10.1074/jbc.m115.655654","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m115.655654","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3937567","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4528126","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4528126","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4528126","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biol Chem","raw_type":"Text"},{"id":"pmid:26105055","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26105055","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of biological chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:bib-pubdb1.desy.de:322403","doi":null,"is_oa":false,"landing_page_url":"https://bib-pubdb1.desy.de/record/322403","pdf_url":null,"source":{"id":"https://openalex.org/S4306400383","display_name":"DESY Publication Database (PUBDB) (Deutsches Elektronen-Synchrotron)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801876189","host_organization_name":"Deutsches Elektronen-Synchrotron DESY","host_organization_lineage":["https://openalex.org/I2801876189"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The journal of biological chemistry 290(32), 19597 - 19613 (2015). doi:10.1074/jbc.M115.655654","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:helmholtz.HZB:107153","doi":null,"is_oa":true,"landing_page_url":"https://www.helmholtz-berlin.de/pubbin/oai_publication?VT=1&ID=107153","pdf_url":null,"source":{"id":"https://openalex.org/S4306402598","display_name":"HZB Repository (Helmholtz-Zentrum Berlin f\u00fcr Materialien und Energie GmbH (HZB))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I3018134672","host_organization_name":"Helmholtz Munich","host_organization_lineage":["https://openalex.org/I3018134672"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Chemistry 290 2015 , p. 19597 19613","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:publica.fraunhofer.de:publica/241806","doi":null,"is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/241806","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1074/jbc.m115.655654","doi":"https://doi.org/10.1074/jbc.m115.655654","is_oa":true,"landing_page_url":"https://doi.org/10.1074/jbc.m115.655654","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W76048665","https://openalex.org/W255996521","https://openalex.org/W1515034295","https://openalex.org/W1533469692","https://openalex.org/W1607931568","https://openalex.org/W1812391263","https://openalex.org/W1966071060","https://openalex.org/W1967390330","https://openalex.org/W1969641905","https://openalex.org/W1970991913","https://openalex.org/W1973035681","https://openalex.org/W1976167023","https://openalex.org/W2000479572","https://openalex.org/W2001641653","https://openalex.org/W2002351910","https://openalex.org/W2003564377","https://openalex.org/W2015593638","https://openalex.org/W2019254756","https://openalex.org/W2022006512","https://openalex.org/W2028527480","https://openalex.org/W2029662163","https://openalex.org/W2040820919","https://openalex.org/W2057593710","https://openalex.org/W2069663555","https://openalex.org/W2070265193","https://openalex.org/W2075016274","https://openalex.org/W2078752695","https://openalex.org/W2080703391","https://openalex.org/W2087646013","https://openalex.org/W2099540110","https://openalex.org/W2102496935","https://openalex.org/W2104043602","https://openalex.org/W2114622716","https://openalex.org/W2121177222","https://openalex.org/W2127122014","https://openalex.org/W2132309217","https://openalex.org/W2133179696","https://openalex.org/W2134201060","https://openalex.org/W2135840745","https://openalex.org/W2138145776","https://openalex.org/W2141294282","https://openalex.org/W2141563676","https://openalex.org/W2144081223","https://openalex.org/W2144362290","https://openalex.org/W2146787746","https://openalex.org/W2147874841","https://openalex.org/W2150187215","https://openalex.org/W2150444353","https://openalex.org/W2150569101","https://openalex.org/W2150926065","https://openalex.org/W2152207030","https://openalex.org/W2153562609","https://openalex.org/W2155403267","https://openalex.org/W2159211495","https://openalex.org/W2159686118","https://openalex.org/W2169540909","https://openalex.org/W2180229411","https://openalex.org/W2883755802"],"related_works":["https://openalex.org/W3132513662","https://openalex.org/W2150187215","https://openalex.org/W6887678222","https://openalex.org/W2587803831","https://openalex.org/W2040820919","https://openalex.org/W2102496935","https://openalex.org/W3043130611","https://openalex.org/W7018975572","https://openalex.org/W7024801295","https://openalex.org/W1515034295"],"abstract_inverted_index":{"For":[0],"host":[1],"colonization,":[2],"the":[3,23,30,34,47,103,122],"human":[4],"fungal":[5,143],"pathogen":[6],"Candida":[7],"glabrata":[8,140],"is":[9],"known":[10],"to":[11],"utilize":[12],"a":[13,41,80],"large":[14,42],"family":[15,124],"of":[16,46,51,61,83],"highly":[17],"related":[18,142],"surface-exposed":[19],"cell":[20,91],"wall":[21],"proteins,":[22],"lectin-like":[24,75],"epithelial":[25,90],"adhesins":[26,135],"(Epas).":[27],"To":[28],"reveal":[29],"structure-function":[31],"relationships":[32,120],"within":[33,102,121],"entire":[35],"Epa":[36,53,105,123],"family,":[37],"we":[38],"have":[39,136],"performed":[40],"scale":[43],"functional":[44,129],"analysis":[45],"adhesion":[48],"(A)":[49],"domains":[50,73],"17":[52],"paralogs":[54],"in":[55,138],"combination":[56],"with":[57,64,85],"three-dimensional":[58],"structural":[59,100],"studies":[60],"selected":[62],"members":[63],"cognate":[65],"ligands.":[66],"Our":[67],"study":[68],"shows":[69],"that":[70],"most":[71],"EpaA":[72],"exert":[74],"functions":[76],"and":[77,98,112,131,141],"together":[78],"recognize":[79],"wide":[81],"variety":[82],"glycans":[84],"terminal":[86],"galactosides":[87],"for":[88,128],"conferring":[89],"adhesion.":[92],"We":[93],"further":[94],"identify":[95],"several":[96],"conserved":[97],"variable":[99],"features":[101,115],"diverse":[104],"ligand":[106],"binding":[107],"pockets,":[108],"which":[109],"affect":[110],"affinity":[111],"specificity.":[113],"These":[114],"rationalize":[116],"why":[117],"mere":[118],"phylogenetic":[119],"are":[125],"weak":[126],"indicators":[127],"classification":[130],"explain":[132],"how":[133],"Epa-like":[134],"evolved":[137],"C.":[139],"species.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}