{"id":"https://openalex.org/W2274993389","doi":"https://doi.org/10.3389/fphys.2016.00049","title":"The Nervous System Orchestrates and Integrates Craniofacial Development: A Review","display_name":"The Nervous System Orchestrates and Integrates Craniofacial Development: A Review","publication_year":2016,"publication_date":"2016-02-19","ids":{"openalex":"https://openalex.org/W2274993389","doi":"https://doi.org/10.3389/fphys.2016.00049","mag":"2274993389","pmid":"https://pubmed.ncbi.nlm.nih.gov/26924989","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4759458"},"language":"en","primary_location":{"id":"doi:10.3389/fphys.2016.00049","doi":"https://doi.org/10.3389/fphys.2016.00049","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2016.00049","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2016.00049/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fphys.2016.00049/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076800395","display_name":"Igor I. Adameyko","orcid":"https://orcid.org/0000-0001-5471-0356","observed_orcids":["https://orcid.org/0000-0001-5471-0356"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","SE"],"is_corresponding":true,"raw_author_name":"Igor Adameyko","raw_affiliation_strings":["Department of Physiology and Pharmacology, Karolinska InstitutetStockholm, Sweden; Department of Molecular Neurosciences, Center of Brain Research, Medical University of ViennaVienna, Austria","Department of Molecular Neurosciences, Center of Brain Research, Medical University of Vienna, Vienna, Austria","Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska InstitutetStockholm, Sweden; Department of Molecular Neurosciences, Center of Brain Research, Medical University of ViennaVienna, Austria","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Molecular Neurosciences, Center of Brain Research, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019700436","display_name":"Kaj Fried","orcid":"https://orcid.org/0000-0002-9997-7078","observed_orcids":["https://orcid.org/0000-0002-9997-7078"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Kaj Fried","raw_affiliation_strings":["Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019700436","https://openalex.org/A5076800395"],"corresponding_institution_ids":["https://openalex.org/I28166907","https://openalex.org/I76134821"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.7507,"has_fulltext":true,"cited_by_count":78,"citation_normalized_percentile":{"value":0.60562887,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"7","issue":null,"first_page":"49","last_page":"49"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.6758000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.6758000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11679","display_name":"Craniofacial Disorders and Treatments","score":0.20810000598430634,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.031099999323487282,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/craniofacial-development","display_name":"craniofacial development","score":1.0},{"id":"https://openalex.org/keywords/nervous-system","display_name":"nervous system","score":0.7839999794960022},{"id":"https://openalex.org/keywords/peripheral-nerves","display_name":"peripheral nerves","score":0.9330000281333923},{"id":"https://openalex.org/keywords/neural-crest","display_name":"neural crest","score":0.8619999885559082},{"id":"https://openalex.org/keywords/morphogens","display_name":"morphogens","score":0.7059999704360962},{"id":"https://openalex.org/keywords/head-morphogenesis","display_name":"head morphogenesis","score":0.578000009059906},{"id":"https://openalex.org/keywords/jaw-development","display_name":"jaw development","score":0.6970000267028809},{"id":"https://openalex.org/keywords/neural-crest-derived-cells","display_name":"neural crest-derived cells","score":0.6029999852180481},{"id":"https://openalex.org/keywords/tissue-regeneration","display_name":"tissue regeneration","score":0.42899999022483826}],"concepts":[{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.8768501877784729},{"id":"https://openalex.org/C2781245598","wikidata":"https://www.wikidata.org/wiki/Q5182134","display_name":"Craniofacial","level":2,"score":0.6976974010467529},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.685463547706604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6195350885391235},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.5706299543380737},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.5592589974403381},{"id":"https://openalex.org/C2780915607","wikidata":"https://www.wikidata.org/wiki/Q323438","display_name":"Mesoderm","level":4,"score":0.5480733513832092},{"id":"https://openalex.org/C2780071072","wikidata":"https://www.wikidata.org/wiki/Q5182130","display_name":"Cranial neural crest","level":4,"score":0.535977303981781},{"id":"https://openalex.org/C197849852","wikidata":"https://www.wikidata.org/wiki/Q2314823","display_name":"Neural plate","level":4,"score":0.5236432552337646},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.5178163647651672},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.47205764055252075},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4526703655719757},{"id":"https://openalex.org/C2780594696","wikidata":"https://www.wikidata.org/wiki/Q1127402","display_name":"Neural tube","level":3,"score":0.427082359790802},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.4235355854034424},{"id":"https://openalex.org/C2777164004","wikidata":"https://www.wikidata.org/wiki/Q331858","display_name":"Endoderm","level":4,"score":0.4207427501678467},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.18684688210487366},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.18619531393051147},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1714763343334198},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.13005393743515015},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fphys.2016.00049","doi":"https://doi.org/10.3389/fphys.2016.00049","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2016.00049","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2016.00049/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3737894","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4759458","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4759458","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4759458","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Physiol","raw_type":"Text"},{"id":"pmid:26924989","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26924989","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in physiology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:7fdebe0e8cbf4425a4fe0d4190f50baa","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7fdebe0e8cbf4425a4fe0d4190f50baa","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Physiology, Vol 7 (2016)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fphys.2016.00049","doi":"https://doi.org/10.3389/fphys.2016.00049","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fphys.2016.00049","pdf_url":"https://www.frontiersin.org/articles/10.3389/fphys.2016.00049/pdf","source":{"id":"https://openalex.org/S52732750","display_name":"Frontiers in Physiology","issn_l":"1664-042X","issn":["1664-042X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Physiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309792","display_name":"\u00c5ke Wiberg Stiftelse","ror":"https://ror.org/03htnqd27"},{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320323925","display_name":"Bertil H\u00e5llstens Forskningsstiftelse","ror":"https://ror.org/02gss4s58"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2274993389.pdf","grobid_xml":"https://content.openalex.org/works/W2274993389.grobid-xml"},"referenced_works_count":186,"referenced_works":["https://openalex.org/W58124601","https://openalex.org/W94022262","https://openalex.org/W97012183","https://openalex.org/W121931614","https://openalex.org/W187961754","https://openalex.org/W606713268","https://openalex.org/W642892146","https://openalex.org/W1505910081","https://openalex.org/W1523121836","https://openalex.org/W1532683920","https://openalex.org/W1542582845","https://openalex.org/W1544473728","https://openalex.org/W1561890398","https://openalex.org/W1593622414","https://openalex.org/W1599076673","https://openalex.org/W1602222357","https://openalex.org/W1635301188","https://openalex.org/W1705186225","https://openalex.org/W1803002100","https://openalex.org/W1816245218","https://openalex.org/W1835943580","https://openalex.org/W1843210218","https://openalex.org/W1867810146","https://openalex.org/W1901103270","https://openalex.org/W1901179771","https://openalex.org/W1918696209","https://openalex.org/W1932659519","https://openalex.org/W1958141299","https://openalex.org/W1964150543","https://openalex.org/W1969795967","https://openalex.org/W1973193723","https://openalex.org/W1973687750","https://openalex.org/W1974519086","https://openalex.org/W1975178371","https://openalex.org/W1975997945","https://openalex.org/W1976934015","https://openalex.org/W1977144442","https://openalex.org/W1978886818","https://openalex.org/W1979603337","https://openalex.org/W1980893846","https://openalex.org/W1980958926","https://openalex.org/W1981465866","https://openalex.org/W1981483041","https://openalex.org/W1983735967","https://openalex.org/W1985690728","https://openalex.org/W1985956372","https://openalex.org/W1989920829","https://openalex.org/W1990847940","https://openalex.org/W1992797254","https://openalex.org/W1993852116","https://openalex.org/W1994553956","https://openalex.org/W1996916826","https://openalex.org/W1997035797","https://openalex.org/W1998099768","https://openalex.org/W1999139999","https://openalex.org/W2000299016","https://openalex.org/W2000465700","https://openalex.org/W2004883547","https://openalex.org/W2006070772","https://openalex.org/W2008458502","https://openalex.org/W2010542741","https://openalex.org/W2011640246","https://openalex.org/W2012494987","https://openalex.org/W2013204606","https://openalex.org/W2014284783","https://openalex.org/W2015135001","https://openalex.org/W2015412821","https://openalex.org/W2016895566","https://openalex.org/W2017478350","https://openalex.org/W2018646456","https://openalex.org/W2020969308","https://openalex.org/W2021841868","https://openalex.org/W2022272931","https://openalex.org/W2023248179","https://openalex.org/W2024629463","https://openalex.org/W2025065961","https://openalex.org/W2025921479","https://openalex.org/W2027275966","https://openalex.org/W2027830931","https://openalex.org/W2028536875","https://openalex.org/W2029034837","https://openalex.org/W2034760981","https://openalex.org/W2035465868","https://openalex.org/W2036145275","https://openalex.org/W2037317989","https://openalex.org/W2038248149","https://openalex.org/W2040145443","https://openalex.org/W2040719077","https://openalex.org/W2041738284","https://openalex.org/W2041884290","https://openalex.org/W2042578402","https://openalex.org/W2042642964","https://openalex.org/W2047284392","https://openalex.org/W2047284741","https://openalex.org/W2047786610","https://openalex.org/W2048161575","https://openalex.org/W2048209216","https://openalex.org/W2048672935","https://openalex.org/W2048957956","https://openalex.org/W2050472029","https://openalex.org/W2052873380","https://openalex.org/W2054383886","https://openalex.org/W2056236983","https://openalex.org/W2056588007","https://openalex.org/W2061135487","https://openalex.org/W2061826308","https://openalex.org/W2063452242","https://openalex.org/W2064694357","https://openalex.org/W2066205648","https://openalex.org/W2068414825","https://openalex.org/W2073290778","https://openalex.org/W2073726708","https://openalex.org/W2073913252","https://openalex.org/W2074220720","https://openalex.org/W2076491580","https://openalex.org/W2079953735","https://openalex.org/W2080247229","https://openalex.org/W2085912440","https://openalex.org/W2087050089","https://openalex.org/W2089813986","https://openalex.org/W2091514845","https://openalex.org/W2092389298","https://openalex.org/W2093064905","https://openalex.org/W2095153889","https://openalex.org/W2096929333","https://openalex.org/W2104295566","https://openalex.org/W2104869587","https://openalex.org/W2106875028","https://openalex.org/W2110519645","https://openalex.org/W2111806313","https://openalex.org/W2119056481","https://openalex.org/W2119635284","https://openalex.org/W2120231073","https://openalex.org/W2120577112","https://openalex.org/W2123775246","https://openalex.org/W2123954788","https://openalex.org/W2124585965","https://openalex.org/W2125723268","https://openalex.org/W2126626234","https://openalex.org/W2129102004","https://openalex.org/W2129239327","https://openalex.org/W2129924682","https://openalex.org/W2130940139","https://openalex.org/W2131176598","https://openalex.org/W2131823580","https://openalex.org/W2132982633","https://openalex.org/W2133285281","https://openalex.org/W2134374915","https://openalex.org/W2139602536","https://openalex.org/W2139685257","https://openalex.org/W2139836251","https://openalex.org/W2142092370","https://openalex.org/W2142649698","https://openalex.org/W2144292993","https://openalex.org/W2146717124","https://openalex.org/W2147774449","https://openalex.org/W2147822820","https://openalex.org/W2148909614","https://openalex.org/W2150987011","https://openalex.org/W2153405537","https://openalex.org/W2154413552","https://openalex.org/W2156757115","https://openalex.org/W2156925261","https://openalex.org/W2157436078","https://openalex.org/W2157592788","https://openalex.org/W2158966094","https://openalex.org/W2159252299","https://openalex.org/W2163109891","https://openalex.org/W2166666678","https://openalex.org/W2168229205","https://openalex.org/W2168302035","https://openalex.org/W2168468808","https://openalex.org/W2168888069","https://openalex.org/W2183778377","https://openalex.org/W2188019112","https://openalex.org/W2220832108","https://openalex.org/W2333219176","https://openalex.org/W2404941226","https://openalex.org/W2412691829","https://openalex.org/W2418915448","https://openalex.org/W2463417921","https://openalex.org/W2949584518","https://openalex.org/W4240659265","https://openalex.org/W4246121813","https://openalex.org/W6603882764","https://openalex.org/W6763879665"],"related_works":["https://openalex.org/W2911110103","https://openalex.org/W4239143774","https://openalex.org/W2464141521","https://openalex.org/W2038434413","https://openalex.org/W2074797127","https://openalex.org/W4235686459","https://openalex.org/W2463417921","https://openalex.org/W3112208380","https://openalex.org/W16088872","https://openalex.org/W3153874610"],"abstract_inverted_index":{"Development":[0],"of":[1,11,38,68,95,101,111,124],"a":[2,5,9,46,60,99,132],"head":[3],"is":[4],"dazzlingly":[6],"complex":[7],"process:":[8],"number":[10],"distinct":[12],"cellular":[13,135],"sources":[14,136],"including":[15,165],"cranial":[16],"ecto-":[17],"and":[18,21,27,45,53,72,89,151,158,173],"endoderm,":[19],"mesoderm":[20],"neural":[22,41,170],"crest":[23,171],"contribute":[24,161],"to":[25,59,130,154,162],"facial":[26],"other":[28],"structures.":[29],"In":[30,141],"the":[31,84,93,107,121,125,147,168],"head,":[32],"an":[33,66],"extremely":[34],"fine-tuned":[35],"developmental":[36],"coordination":[37],"CNS,":[39],"peripheral":[40,90,156],"components,":[42],"sensory":[43,69],"organs":[44],"musculo-skeletal":[47],"apparatus":[48],"occurs,":[49],"which":[50],"provides":[51],"protection":[52],"functional":[54],"integration.":[55],"The":[56,109],"face":[57],"can":[58],"large":[61],"extent":[62],"be":[63],"considered":[64],"as":[65,98,114],"assembly":[67],"systems":[70],"encased":[71],"functionally":[73],"fused":[74],"with":[75],"appendages":[76],"represented":[77],"by":[78],"jaws.":[79],"Here":[80],"we":[81,115,144],"review":[82,143],"how":[83,155],"developing":[85],"brain,":[86],"neurogenic":[87],"placodes":[88],"nerves":[91,157],"influence":[92],"morphogenesis":[94],"surrounding":[96],"tissues":[97],"part":[100],"various":[102],"general":[103],"integrative":[104],"processes":[105],"in":[106,138,175],"head.":[108],"mechanisms":[110],"this":[112,142],"impact,":[113],"understand":[116],"it":[117],"now,":[118],"span":[119],"from":[120],"targeted":[122],"release":[123],"morphogens":[126],"necessary":[127],"for":[128,134],"shaping":[129],"providing":[131],"niche":[133],"required":[137],"later":[139],"development.":[140],"also":[145],"discuss":[146],"most":[148],"recent":[149],"findings":[150],"ideas":[152],"related":[153],"nerve-associated":[159],"cells":[160],"craniofacial":[163],"development,":[164],"teeth,":[166],"during":[167],"post-":[169],"period":[172],"potentially":[174],"regeneration.":[176]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}