{"id":"https://openalex.org/W2274204875","doi":"https://doi.org/10.1155/2016/7314971","title":"Overexpression ofAaWRKY1Leads to an Enhanced Content of Artemisinin inArtemisia annua","display_name":"Overexpression ofAaWRKY1Leads to an Enhanced Content of Artemisinin inArtemisia annua","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2274204875","doi":"https://doi.org/10.1155/2016/7314971","mag":"2274204875","pmid":"https://pubmed.ncbi.nlm.nih.gov/27064403","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4809039"},"language":"en","primary_location":{"id":"doi:10.1155/2016/7314971","doi":"https://doi.org/10.1155/2016/7314971","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/7314971","pdf_url":"https://downloads.hindawi.com/journals/bmri/2016/7314971.pdf","source":{"id":"https://openalex.org/S1010394304","display_name":"BioMed Research International","issn_l":"1110-7243","issn":["1110-7243","1110-7251","2314-6133","2314-6141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","medline","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed Research International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://downloads.hindawi.com/journals/bmri/2016/7314971.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004691905","display_name":"Weimin Jiang","orcid":"https://orcid.org/0000-0002-2546-5256","observed_orcids":["https://orcid.org/0000-0002-2546-5256"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weimin Jiang","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057923496","display_name":"Xueqing Fu","orcid":"https://orcid.org/0000-0003-4399-9830","observed_orcids":["https://orcid.org/0000-0003-4399-9830"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueqing Fu","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101402749","display_name":"Qifang Pan","orcid":"https://orcid.org/0000-0002-8183-4343","observed_orcids":["https://orcid.org/0000-0002-8183-4343"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qifang Pan","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027778305","display_name":"Yueli Tang","orcid":"https://orcid.org/0000-0002-9720-7555","observed_orcids":["https://orcid.org/0000-0002-9720-7555"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueli Tang","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039516755","display_name":"Qian Shen","orcid":"https://orcid.org/0000-0002-4621-4659","observed_orcids":["https://orcid.org/0000-0002-4621-4659"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Shen","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009951838","display_name":"Zongyou Lv","orcid":"https://orcid.org/0000-0003-1965-8809","observed_orcids":["https://orcid.org/0000-0003-1965-8809"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zongyou Lv","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050877812","display_name":"Tingxiang Yan","orcid":"https://orcid.org/0000-0002-2068-859X","observed_orcids":["https://orcid.org/0000-0002-2068-859X"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingxiang Yan","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101621449","display_name":"Pu Shi","orcid":"https://orcid.org/0000-0002-5204-4107","observed_orcids":["https://orcid.org/0000-0002-5204-4107"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pu Shi","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100435302","display_name":"Ling Li","orcid":"https://orcid.org/0000-0001-5194-0391","observed_orcids":["https://orcid.org/0000-0001-5194-0391"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ling Li","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072931223","display_name":"Lida Zhang","orcid":"https://orcid.org/0000-0002-5207-2458","observed_orcids":["https://orcid.org/0000-0002-5207-2458"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lida Zhang","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100389619","display_name":"Guofeng Wang","orcid":"https://orcid.org/0000-0001-8459-0308","observed_orcids":["https://orcid.org/0000-0001-8459-0308"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guofeng Wang","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100861025","display_name":"Xiaofen Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaofen Sun","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074496850","display_name":"Kexuan Tang","orcid":"https://orcid.org/0000-0002-8748-9624","observed_orcids":["https://orcid.org/0000-0002-8748-9624"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kexuan Tang","raw_affiliation_strings":["Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Urban Agriculture (South) Ministry of Agriculture, Plant Biotechnology Research Center, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China","institution_ids":["https://openalex.org/I183067930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5074496850"],"corresponding_institution_ids":["https://openalex.org/I183067930"],"apc_list":{"value":2680,"currency":"USD","value_usd":2680},"apc_paid":{"value":2680,"currency":"USD","value_usd":2680},"fwci":2.0209,"has_fulltext":true,"cited_by_count":72,"citation_normalized_percentile":{"value":0.86697935,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"2016","issue":null,"first_page":"1","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artemisia-annua","display_name":"Artemisia annua","score":0.921999990940094},{"id":"https://openalex.org/keywords/artemisinin-biosynthesis","display_name":"artemisinin biosynthesis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/overexpression","display_name":"overexpression","score":0.6389999985694885},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.5669999718666077},{"id":"https://openalex.org/keywords/ads","display_name":"ADS","score":0.39899998903274536},{"id":"https://openalex.org/keywords/cyp","display_name":"CYP","score":0.8999999761581421},{"id":"https://openalex.org/keywords/genetically-modified-plants","display_name":"transgenic plants","score":0.8199999928474426},{"id":"https://openalex.org/keywords/artemisinin-yield","display_name":"artemisinin yield","score":0.7670000195503235},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C2779691961","wikidata":"https://www.wikidata.org/wiki/Q1308044","display_name":"Artemisia annua","level":5,"score":0.9905792474746704},{"id":"https://openalex.org/C2776120307","wikidata":"https://www.wikidata.org/wiki/Q426921","display_name":"Artemisinin","level":4,"score":0.9838247299194336},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5186680555343628},{"id":"https://openalex.org/C2777389444","wikidata":"https://www.wikidata.org/wiki/Q156421","display_name":"Artemisia","level":2,"score":0.4673882722854614},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34276360273361206},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30740514397621155},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.14545604586601257},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.11557576060295105},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.08439883589744568}],"mesh":[{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014026","descriptor_name":"Nicotiana","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014026","descriptor_name":"Nicotiana","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037621","descriptor_name":"Artemisinins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D037621","descriptor_name":"Artemisinins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1155/2016/7314971","doi":"https://doi.org/10.1155/2016/7314971","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/7314971","pdf_url":"https://downloads.hindawi.com/journals/bmri/2016/7314971.pdf","source":{"id":"https://openalex.org/S1010394304","display_name":"BioMed Research International","issn_l":"1110-7243","issn":["1110-7243","1110-7251","2314-6133","2314-6141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","medline","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed Research International","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3796157","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4809039","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:27064403","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27064403","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed research international","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4809039","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4809039/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomed Res Int","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/2016/7314971","doi":"https://doi.org/10.1155/2016/7314971","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2016/7314971","pdf_url":"https://downloads.hindawi.com/journals/bmri/2016/7314971.pdf","source":{"id":"https://openalex.org/S1010394304","display_name":"BioMed Research International","issn_l":"1110-7243","issn":["1110-7243","1110-7251","2314-6133","2314-6141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","medline","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BioMed Research International","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G499971151","display_name":null,"funder_award_id":"2011AA100605","funder_id":"https://openalex.org/F4320322999","funder_display_name":"Shanghai Jiao Tong University"}],"funders":[{"id":"https://openalex.org/F4320322999","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2274204875.pdf","grobid_xml":"https://content.openalex.org/works/W2274204875.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W1525232568","https://openalex.org/W1571265670","https://openalex.org/W1607854320","https://openalex.org/W1719348349","https://openalex.org/W1969962785","https://openalex.org/W1973280892","https://openalex.org/W1973958528","https://openalex.org/W1983355052","https://openalex.org/W1985490305","https://openalex.org/W1986111317","https://openalex.org/W1988392160","https://openalex.org/W1992324215","https://openalex.org/W1992362149","https://openalex.org/W1995977555","https://openalex.org/W1998303296","https://openalex.org/W1998325904","https://openalex.org/W2005254097","https://openalex.org/W2015823022","https://openalex.org/W2016348993","https://openalex.org/W2017640872","https://openalex.org/W2019281554","https://openalex.org/W2028886234","https://openalex.org/W2033812623","https://openalex.org/W2036368368","https://openalex.org/W2038771253","https://openalex.org/W2039034225","https://openalex.org/W2045115500","https://openalex.org/W2057823601","https://openalex.org/W2060685213","https://openalex.org/W2064909918","https://openalex.org/W2065275664","https://openalex.org/W2067884797","https://openalex.org/W2070287693","https://openalex.org/W2071924031","https://openalex.org/W2077381490","https://openalex.org/W2079383956","https://openalex.org/W2080053579","https://openalex.org/W2082905440","https://openalex.org/W2083226567","https://openalex.org/W2088639933","https://openalex.org/W2090020964","https://openalex.org/W2104072286","https://openalex.org/W2107029656","https://openalex.org/W2107277218","https://openalex.org/W2107593640","https://openalex.org/W2108488573","https://openalex.org/W2112522116","https://openalex.org/W2114360920","https://openalex.org/W2115186431","https://openalex.org/W2117756181","https://openalex.org/W2118782447","https://openalex.org/W2118846876","https://openalex.org/W2124259686","https://openalex.org/W2129447528","https://openalex.org/W2145813726","https://openalex.org/W2146451828","https://openalex.org/W2152038789","https://openalex.org/W2152443621","https://openalex.org/W2162905217","https://openalex.org/W2164314128","https://openalex.org/W2165818994","https://openalex.org/W2184709802","https://openalex.org/W2466235598","https://openalex.org/W2951197366","https://openalex.org/W4236404432"],"related_works":["https://openalex.org/W3138278196","https://openalex.org/W2088639933","https://openalex.org/W4383373474","https://openalex.org/W2165818994","https://openalex.org/W2581239899","https://openalex.org/W4366977276","https://openalex.org/W2133898951","https://openalex.org/W2563084198","https://openalex.org/W1984156348","https://openalex.org/W2983204290"],"abstract_inverted_index":{"Artemisinin":[0],"is":[1,14,33],"an":[2],"effective":[3],"component":[4],"of":[5,11,18,30,64,86,92,130,136,149],"drugs":[6],"against":[7],"malaria.":[8],"The":[9,90],"regulation":[10,150],"artemisinin":[12,19,39,100,113,131,152],"biosynthesis":[13,153],"at":[15],"the":[16,28,34,62,96,112,128,134,147,158],"forefront":[17],"research.":[20],"Previous":[21],"studies":[22],"showed":[23,124],"that":[24,125],"AaWRKY1":[25,45,76,87,126],"can":[26],"regulate":[27],"expression":[29,85,91,135],"ADS,":[31],"which":[32],"first":[35],"key":[36,97],"enzyme":[37],"in":[38,54,99,106,117,157],"biosynthetic":[40,101],"pathway.":[41],"In":[42],"this":[43],"study,":[44],"was":[46,71,103],"cloned,":[47],"and":[48,52,79,94,139],"it":[49],"activated":[50],"ADSpro":[51],"CYPpro":[53],"tobacco":[55],"using":[56],"dual-LUC":[57],"assay.":[58],"To":[59],"further":[60],"study":[61],"function":[63],"AaWRKY1,":[65],"pCAMBIA2300-AaWRKY1":[66],"construct":[67],"under":[68],"35S":[69],"promoter":[70],"generated.":[72],"Transgenic":[73],"plants":[74],"containing":[75],"were":[77,88],"obtained,":[78],"four":[80],"independent":[81],"lines":[82],"with":[83],"high":[84],"analyzed.":[89],"ADS":[93,138],"CYP,":[95],"enzymes":[98],"pathway,":[102],"dramatically":[104],"increased":[105,115,127],"AaWRKY1-overexpressing":[107,118],"A.":[108,119],"annua":[109,120],"plants.":[110,121],"Furthermore,":[111],"yield":[114],"significantly":[116],"These":[122],"results":[123],"content":[129],"by":[132],"regulating":[133],"both":[137],"CYP.":[140],"It":[141],"provides":[142],"a":[143],"new":[144],"insight":[145],"into":[146],"mechanism":[148],"on":[151],"via":[154],"transcription":[155],"factors":[156],"future.":[159]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}