{"id":"https://openalex.org/W2274034541","doi":null,"title":"Model and analysis: Diabetes and obesity","display_name":"Model and analysis: Diabetes and obesity","publication_year":2007,"publication_date":"2007-12-01","ids":{"openalex":"https://openalex.org/W2274034541","mag":"2274034541"},"language":"en","primary_location":{"id":"pmh:oai:ttu-ir.tdl.org:2346/22345","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2346/22345","pdf_url":null,"source":{"id":"https://openalex.org/S4306402519","display_name":"ThinkTech (Texas Tech University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I12315562","host_organization_name":"Texas Tech University","host_organization_lineage":["https://openalex.org/I12315562"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045382497","display_name":"Sam Al-Hashmi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sam Al-Hashmi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5045382497"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.5551999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.5551999807357788,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.3197999894618988,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.04470000043511391,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9599999785423279},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9449999928474426},{"id":"https://openalex.org/keywords/glucose-regulation","display_name":"glucose regulation","score":0.7689999938011169},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8700000047683716},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.9829999804496765},{"id":"https://openalex.org/keywords/pharmacokinetic-simulation","display_name":"pharmacokinetic simulation","score":0.6850000023841858},{"id":"https://openalex.org/keywords/control-theory","display_name":"control theory","score":0.597000002861023},{"id":"https://openalex.org/keywords/impaired-insulin-secretion","display_name":"impaired insulin secretion","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6113939881324768},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6089890003204346},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40736839175224304},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21941998600959778},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.19634509086608887}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ttu-ir.tdl.org:2346/22345","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2346/22345","pdf_url":null,"source":{"id":"https://openalex.org/S4306402519","display_name":"ThinkTech (Texas Tech University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I12315562","host_organization_name":"Texas Tech University","host_organization_lineage":["https://openalex.org/I12315562"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2274034541","doi":null,"is_oa":false,"landing_page_url":"https://ttu-ir.tdl.org/ttu-ir/bitstream/2346/22345/1/AlHashmi_Sam_Thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W561967255","https://openalex.org/W594222009","https://openalex.org/W1481333372","https://openalex.org/W1482417269","https://openalex.org/W1527093032","https://openalex.org/W1553733060","https://openalex.org/W1555818350","https://openalex.org/W1605353467","https://openalex.org/W1860443407","https://openalex.org/W1970654240","https://openalex.org/W1982488301","https://openalex.org/W1986313897","https://openalex.org/W1993683038","https://openalex.org/W1995514808","https://openalex.org/W2005959013","https://openalex.org/W2014259643","https://openalex.org/W2016194457","https://openalex.org/W2019314363","https://openalex.org/W2038833357","https://openalex.org/W2041580344","https://openalex.org/W2042279710","https://openalex.org/W2043569787","https://openalex.org/W2047922146","https://openalex.org/W2048565142","https://openalex.org/W2049275999","https://openalex.org/W2051827443","https://openalex.org/W2058355180","https://openalex.org/W2059020692","https://openalex.org/W2080927900","https://openalex.org/W2095252238","https://openalex.org/W2103031848","https://openalex.org/W2104238031","https://openalex.org/W2104464442","https://openalex.org/W2105779910","https://openalex.org/W2105912552","https://openalex.org/W2126317966","https://openalex.org/W2134324546","https://openalex.org/W2141027252","https://openalex.org/W2142962347","https://openalex.org/W2143070237","https://openalex.org/W2149156474","https://openalex.org/W2151316409","https://openalex.org/W2156353972","https://openalex.org/W2157337717","https://openalex.org/W2166240532","https://openalex.org/W2171407792","https://openalex.org/W2337101260"],"related_works":["https://openalex.org/W2249884511","https://openalex.org/W180102821","https://openalex.org/W2495131116","https://openalex.org/W2949891677","https://openalex.org/W1986198574","https://openalex.org/W219166223","https://openalex.org/W2040796675","https://openalex.org/W2338619015","https://openalex.org/W183817095","https://openalex.org/W3139001870"],"abstract_inverted_index":{"The":[0,21,46,122,167],"thesis":[1,123,168],"is":[2,26,51,62,75,86,184],"a":[3,7,40,76,89,96,133,140,147,162,206],"further":[4,141],"revision":[5,59],"of":[6,23,31,44,49,83,95,112,128,135,146,161,178,194],"mathematical":[8,90],"model":[9,25,85,91],"based":[10,52],"upon":[11,53],"Sorensen\u2019s":[12],"progress":[13,204],"and":[14,57,116,201],"Alvehag\u2019s":[15],"modification":[16],"under":[17,151],"Dr":[18],"Clyde":[19],"Martin.":[20],"intention":[22],"the":[24,29,37,54,65,72,80,84,93,126,144,171,175,192,203],"to":[27,63,87,143,173,186,189],"address":[28,64],"aspect":[30,61],"regulating":[32],"glucose":[33],"concentration":[34],"with":[35],"in":[36,71],"body":[38,150],"from":[39],"control":[41],"theory":[42],"point":[43],"view.":[45],"chosen":[47],"method":[48],"simulation":[50],"pharmacokinetic":[55],"approach;":[56],"our":[58],"main":[60],"effect":[66],"free":[67],"fatty":[68],"acid":[69],"(FFA)":[70],"blood.":[73],"This":[74],"necessary":[77],"step":[78],"since":[79],"primary":[81],"role":[82],"establish":[88],"simulating":[92],"behavior":[94,145,177],"type":[97,113,119,163,197,208],"II":[98,102,114,120,164,198,209],"diabetic":[99,165,199,210],"patient.":[100,166],"Type":[101],"diabetes":[103,115],"can":[104],"be":[105,187],"classified":[106],"into":[107,205],"categories;":[108],"such":[109],"early":[110,159,195],"stages":[111,160,196],"fully":[117,190,207],"developed":[118],"diabetes.":[121],"emphasis":[124],"on":[125],"affect":[127],"insulin":[129,153,180],"resistance":[130],"by":[131],"including":[132],"sub-model":[134],"adipose":[136],"tissue;":[137],"hence":[138],"creating":[139],"understanding":[142],"healthy":[148],"human":[149],"induced":[152],"resistance,":[154],"or":[155,158],"obese":[156],"individuals,":[157],"remains":[169],"lacking":[170],"ability":[172],"simulate":[174,191],"unique":[176],"impaired":[179],"secretion.":[181],"Further":[182],"research":[183],"needed":[185],"able":[188],"response":[193],"patients":[200],"follow":[202],"patients.":[211]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-08-18T07:49:30.821534","created_date":"2016-06-24T00:00:00"}
