{"id":"https://openalex.org/W2269611535","doi":"https://doi.org/10.1200/jco.1998.16.6.2290","title":"Monitoring methotrexate levels in osteosarcoma.","display_name":"Monitoring methotrexate levels in osteosarcoma.","publication_year":1998,"publication_date":"1998-06-01","ids":{"openalex":"https://openalex.org/W2269611535","doi":"https://doi.org/10.1200/jco.1998.16.6.2290","mag":"2269611535","pmid":"https://pubmed.ncbi.nlm.nih.gov/9626240"},"language":"en","primary_location":{"id":"doi:10.1200/jco.1998.16.6.2290","doi":"https://doi.org/10.1200/jco.1998.16.6.2290","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.1998.16.6.2290","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"letter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032743242","display_name":"Richard Greg Gorlick","orcid":"https://orcid.org/0000-0001-8995-2929","observed_orcids":["https://orcid.org/0000-0001-8995-2929"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Gorlick","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010913859","display_name":"Paul A. Meyers","orcid":"https://orcid.org/0000-0001-6146-6101","observed_orcids":["https://orcid.org/0000-0001-6146-6101"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Meyers","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057588239","display_name":"Michael G. Kellick","orcid":"https://orcid.org/0000-0002-7934-5508","observed_orcids":["https://orcid.org/0000-0002-7934-5508"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Kellick","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109128786","display_name":"J.R. Bertino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J R Bertino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"6","first_page":"2290","last_page":"2291"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9940000176429749},{"id":"https://openalex.org/keywords/osteosarcoma","display_name":"osteosarcoma","score":0.9459999799728394},{"id":"https://openalex.org/keywords/therapeutic-drug-monitoring","display_name":"therapeutic drug monitoring","score":0.8679999709129333},{"id":"https://openalex.org/keywords/chemotherapy-dosing","display_name":"chemotherapy dosing","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8313103914260864},{"id":"https://openalex.org/C2777760704","wikidata":"https://www.wikidata.org/wiki/Q549534","display_name":"Osteosarcoma","level":2,"score":0.7941855192184448},{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.7124336361885071},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.5960203409194946},{"id":"https://openalex.org/C2776598537","wikidata":"https://www.wikidata.org/wiki/Q1812651","display_name":"Clinical Oncology","level":3,"score":0.5442237854003906},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5015192031860352},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4281850755214691},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.3418152630329132},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.21345213055610657},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.20113414525985718},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.05612066388130188}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012516","descriptor_name":"Osteosarcoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D017024","descriptor_name":"Chemotherapy, Adjuvant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1200/jco.1998.16.6.2290","doi":"https://doi.org/10.1200/jco.1998.16.6.2290","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.1998.16.6.2290","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:9626240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9626240","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology","raw_type":"Comment"},{"id":"pmh:oai:alma.01RUT_INST:11665006700004646","doi":null,"is_oa":false,"landing_page_url":"https://scholarship.libraries.rutgers.edu/esploro/outputs/journalArticle/Monitoring-methotrexate-levels-in-osteosarcoma/991031665863504646","pdf_url":null,"source":{"id":"https://openalex.org/S4306401388","display_name":"Rutgers University Community Repository (Rutgers University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102322142","host_organization_name":"Rutgers, The State University of New Jersey","host_organization_lineage":["https://openalex.org/I102322142"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2384299534","https://openalex.org/W2034987718","https://openalex.org/W2153180030","https://openalex.org/W2137872977","https://openalex.org/W7111094101","https://openalex.org/W2383590841","https://openalex.org/W3136781449","https://openalex.org/W2387219277","https://openalex.org/W1551776566","https://openalex.org/W2378425332"],"abstract_inverted_index":{"Article":[0,2],"Tools":[1,3],"OPTIONS":[4],"&":[5,15],"TOOLS":[6],"Export":[7],"Citation":[8,10],"Track":[9],"Add":[11],"To":[12],"Favorites":[13],"Rights":[14],"Permissions":[16],"COMPANION":[17],"ARTICLES":[18],"No":[19],"companion":[20],"articles":[21,49,58,67,78],"ARTICLE":[22],"CITATION":[23],"DOI:":[24],"10.1200/JCO.1998.16.6.2290":[25],"Journal":[26,89],"of":[27,90,100],"Clinical":[28,91,101],"Oncology":[29,102],"-":[30],"published":[31],"online":[32],"before":[33],"print":[34],"September":[35],"21,":[36],"2016":[37],"PMID:":[38],"9626240":[39],"Monitoring":[40],"methotrexate":[41,85],"levels":[42,86],"in":[43,87],"osteosarcoma.":[44],"R":[45,73,75],"GorlickxR":[46],"GorlickSearch":[47],"for":[48,57,66,77],"by":[50,59,68,79,97],"this":[51,60,69,80],"author":[52,61,70,81],",":[53,62,71],"P":[54],"MeyersxP":[55],"MeyersSearch":[56],"M":[63],"KellickxM":[64],"KellickSearch":[65],"J":[72],"BertinoxJ":[74],"BertinoSearch":[76],"https://doi.org/10.1200/JCO.1998.16.6.2290":[82],"PDF":[83],"\"Monitoring":[84],"osteosarcoma..\"":[88],"Oncology,":[92],"16(6),":[93],"pp.":[94],"2290\u20132291\u00a9":[95],"1998":[96],"American":[98],"Society":[99]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}