{"id":"https://openalex.org/W2265074293","doi":"https://doi.org/10.11501/3133977","title":"\u30e9\u30c3\u30c8\u8102\u80aa\u7d30\u80de\u306b\u304a\u3051\u308b,\u7cd6\u8f38\u9001\u80fd\u304a\u3088\u3073\u30d7\u30ed\u30c6\u30a4\u30f3\u30ad\u30ca\u30fc\u30bcC(PKC)\u6d3b\u6027\u306b\u5bfe\u3059\u308bwortmannin\u306e\u52b9\u679c","display_name":"\u30e9\u30c3\u30c8\u8102\u80aa\u7d30\u80de\u306b\u304a\u3051\u308b,\u7cd6\u8f38\u9001\u80fd\u304a\u3088\u3073\u30d7\u30ed\u30c6\u30a4\u30f3\u30ad\u30ca\u30fc\u30bcC(PKC)\u6d3b\u6027\u306b\u5bfe\u3059\u308bwortmannin\u306e\u52b9\u679c","publication_year":1996,"publication_date":"1996-05-01","ids":{"openalex":"https://openalex.org/W2265074293","doi":"https://doi.org/10.11501/3133977","mag":"2265074293"},"language":"ja","primary_location":{"id":"pmh:oai:repository.lib.gifu-u.ac.jp:123456789/15207","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12099/15207","pdf_url":"http://hdl.handle.net/20.500.12099/15207","source":{"id":"https://openalex.org/S4406922628","display_name":"Gifu University Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"\u535a\u58eb\u8ad6\u6587 (Doctoral dissertation)"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/20.500.12099/15207","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032845526","display_name":"Toshihiko Nagashima","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u5bff\u5f66 \u6c38\u5cf6","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005117301","display_name":"\u9054\u592b \u77f3\u585a","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u9054\u592b \u77f3\u585a","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5033321775","display_name":"\u548c\u7537 \u68b6\u7530","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u548c\u7537 \u68b6\u7530","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"44","issue":"3","first_page":"427","last_page":"434"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.6958000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.6958000063896179,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.0860000029206276,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.06790000200271606,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wortmannin","display_name":"wortmannin","score":0.996999979019165},{"id":"https://openalex.org/keywords/adipocytes","display_name":"adipocytes","score":0.9100000262260437},{"id":"https://openalex.org/keywords/glucose-transport","display_name":"glucose transport","score":0.9290000200271606},{"id":"https://openalex.org/keywords/protein-kinase-c","display_name":"protein kinase C","score":0.9860000014305115},{"id":"https://openalex.org/keywords/rat-adipocytes","display_name":"rat adipocytes","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C2778308172","wikidata":"https://www.wikidata.org/wiki/Q423565","display_name":"Wortmannin","level":4,"score":0.7668952941894531},{"id":"https://openalex.org/C195794163","wikidata":"https://www.wikidata.org/wiki/Q420877","display_name":"Protein kinase C","level":3,"score":0.44641056656837463},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.35143041610717773},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.252041220664978},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20555508136749268},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.13744956254959106},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.09446340799331665},{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.07322216033935547}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:repository.lib.gifu-u.ac.jp:123456789/15207","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12099/15207","pdf_url":"http://hdl.handle.net/20.500.12099/15207","source":{"id":"https://openalex.org/S4406922628","display_name":"Gifu University Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"\u535a\u58eb\u8ad6\u6587 (Doctoral dissertation)"},{"id":"pmh:oai:irdb.nii.ac.jp:01112:0003074559","doi":null,"is_oa":true,"landing_page_url":"https://gifu-u.repo.nii.ac.jp/records/69597","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"},{"id":"pmh:oai:irdb.nii.ac.jp:01112:0005774812","doi":null,"is_oa":false,"landing_page_url":"https://gifu-u.repo.nii.ac.jp/records/71153","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta scholae medicinalis universitatis in Gifu","raw_type":"departmental bulletin paper"},{"id":"mag:2265074293","doi":"https://doi.org/10.11501/3133977","is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/110004464088","pdf_url":null,"source":{"id":"https://openalex.org/S4306548051","display_name":"\u5c90\u961c\u5927\u5b66\u533b\u5b66\u90e8\u7d00\u8981","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313448","host_organization_name":"Gifu University","host_organization_lineage":["https://openalex.org/P4310313448"],"host_organization_lineage_names":["Gifu University"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u5c90\u961c\u5927\u5b66\u533b\u5b66\u90e8\u7d00\u8981","raw_type":null}],"best_oa_location":{"id":"pmh:oai:repository.lib.gifu-u.ac.jp:123456789/15207","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12099/15207","pdf_url":"http://hdl.handle.net/20.500.12099/15207","source":{"id":"https://openalex.org/S4406922628","display_name":"Gifu University Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"\u535a\u58eb\u8ad6\u6587 (Doctoral dissertation)"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.46810001134872437}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2265074293.pdf","grobid_xml":"https://content.openalex.org/works/W2265074293.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W399767232","https://openalex.org/W2127396222","https://openalex.org/W7144515408","https://openalex.org/W2254590338","https://openalex.org/W162488499","https://openalex.org/W619017046","https://openalex.org/W3101954775","https://openalex.org/W591976520","https://openalex.org/W437863174","https://openalex.org/W2746087739"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}