{"id":"https://openalex.org/W2265064114","doi":"https://doi.org/10.4103/1658-354x.159463","title":"Articaine and mepivacaine buccal infiltration in securing mandibular first molar pulp anesthesia following mepivacaine inferior alveolar nerve block: A randomized, double-blind crossover study","display_name":"Articaine and mepivacaine buccal infiltration in securing mandibular first molar pulp anesthesia following mepivacaine inferior alveolar nerve block: A randomized, double-blind crossover study","publication_year":2015,"publication_date":"2015-06-29","ids":{"openalex":"https://openalex.org/W2265064114","doi":"https://doi.org/10.4103/1658-354x.159463","mag":"2265064114","pmid":"https://pubmed.ncbi.nlm.nih.gov/26543456","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4610083"},"language":"en","primary_location":{"id":"doi:10.4103/1658-354x.159463","doi":"https://doi.org/10.4103/1658-354x.159463","is_oa":true,"landing_page_url":"https://doi.org/10.4103/1658-354x.159463","pdf_url":null,"source":{"id":"https://openalex.org/S59148946","display_name":"Saudi Journal of Anaesthesia","issn_l":"0975-3125","issn":["0975-3125","1658-354X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Journal of Anaesthesia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/1658-354x.159463","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052828314","display_name":"Giath Gazal","orcid":"https://orcid.org/0000-0003-1434-0703","observed_orcids":["https://orcid.org/0000-0003-1434-0703"]},"institutions":[{"id":"https://openalex.org/I23075662","display_name":"Taibah University","ror":"https://ror.org/01xv1nn60","country_code":"SA","type":"education","lineage":["https://openalex.org/I23075662"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Giath Gazal","raw_affiliation_strings":["Department of Oral and Maxillofacial, College of Dentistry, Taibah University, Medina, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial, College of Dentistry, Taibah University, Medina, Saudi Arabia","institution_ids":["https://openalex.org/I23075662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048576929","display_name":"AbdullahMuteb Alharbi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23075662","display_name":"Taibah University","ror":"https://ror.org/01xv1nn60","country_code":"SA","type":"education","lineage":["https://openalex.org/I23075662"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Abdullah Muteb Alharbi","raw_affiliation_strings":["Department of Oral and Maxillofacial, College of Dentistry, Taibah University, Medina, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial, College of Dentistry, Taibah University, Medina, Saudi Arabia","institution_ids":["https://openalex.org/I23075662"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112244427","display_name":"Khalid H. Al-Samadani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I23075662","display_name":"Taibah University","ror":"https://ror.org/01xv1nn60","country_code":"SA","type":"education","lineage":["https://openalex.org/I23075662"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Khalid HidayatAllah Al-Samadani","raw_affiliation_strings":["Department of Restorative Dentistry, College of Dentistry, Taibah University, Medina, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Restorative Dentistry, College of Dentistry, Taibah University, Medina, Saudi Arabia","institution_ids":["https://openalex.org/I23075662"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109136802","display_name":"Mohammad Dib Kanaa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801415944","display_name":"Kettering General Hospital","ror":"https://ror.org/032kmqj66","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]},{"id":"https://openalex.org/I4210167175","display_name":"Kettering General Hospital NHS Trust","ror":"https://ror.org/05xh7ac43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210167175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mohammad Dib Kanaa","raw_affiliation_strings":["Department of Oral and Maxillofacial Surgery, Kettering General Hospital, Kettering, NN16 8UZ, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Surgery, Kettering General Hospital, Kettering, NN16 8UZ, United Kingdom","institution_ids":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5052828314"],"corresponding_institution_ids":["https://openalex.org/I23075662"],"apc_list":null,"apc_paid":null,"fwci":2.6801,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.86809982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"9","issue":"4","first_page":"397","last_page":"403"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12145","display_name":"Dental Anxiety and Anesthesia Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12145","display_name":"Dental Anxiety and Anesthesia Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11363","display_name":"Dental Radiography and Imaging","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mepivacaine","display_name":"mepivacaine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/buccal-infiltration","display_name":"buccal infiltration","score":0.9340000152587891},{"id":"https://openalex.org/keywords/inferior-alveolar-nerve-block","display_name":"inferior alveolar nerve block","score":0.9789999723434448},{"id":"https://openalex.org/keywords/mandibular-first-molar","display_name":"mandibular first molar","score":0.9350000023841858},{"id":"https://openalex.org/keywords/local-anesthetic-efficacy","display_name":"local anesthetic efficacy","score":0.6159999966621399},{"id":"https://openalex.org/keywords/dental-anesthesia","display_name":"dental anesthesia","score":0.47200000286102295},{"id":"https://openalex.org/keywords/pulp-testing","display_name":"pulp testing","score":0.35199999809265137},{"id":"https://openalex.org/keywords/postoperative-paresthesia","display_name":"postoperative paresthesia","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C2777347110","wikidata":"https://www.wikidata.org/wiki/Q421297","display_name":"Articaine","level":3,"score":0.9691163301467896},{"id":"https://openalex.org/C2779429755","wikidata":"https://www.wikidata.org/wiki/Q416760","display_name":"Mepivacaine","level":3,"score":0.9184081554412842},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8670060038566589},{"id":"https://openalex.org/C2775856749","wikidata":"https://www.wikidata.org/wiki/Q1538474","display_name":"Inferior alveolar nerve","level":3,"score":0.7840135097503662},{"id":"https://openalex.org/C195735259","wikidata":"https://www.wikidata.org/wiki/Q16963239","display_name":"Buccal administration","level":2,"score":0.5448791980743408},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.5023362636566162},{"id":"https://openalex.org/C2780149897","wikidata":"https://www.wikidata.org/wiki/Q216935","display_name":"Lidocaine","level":2,"score":0.4998488426208496},{"id":"https://openalex.org/C2779773560","wikidata":"https://www.wikidata.org/wiki/Q385981","display_name":"Mandibular nerve","level":3,"score":0.47631344199180603},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.47463807463645935},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.47323593497276306},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4713076055049896},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.06040841341018677},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4103/1658-354x.159463","doi":"https://doi.org/10.4103/1658-354x.159463","is_oa":true,"landing_page_url":"https://doi.org/10.4103/1658-354x.159463","pdf_url":null,"source":{"id":"https://openalex.org/S59148946","display_name":"Saudi Journal of Anaesthesia","issn_l":"0975-3125","issn":["0975-3125","1658-354X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Journal of Anaesthesia","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4610083","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4610083/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4610083/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi J Anaesth","raw_type":"Text"},{"id":"pmid:26543456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26543456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi journal of anaesthesia","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:5c6267a333354f1ea60828d15f11a1c0","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/5c6267a333354f1ea60828d15f11a1c0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Saudi Journal of Anaesthesia, Vol 9, Iss 4, Pp 397-403 (2015)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/1658-354x.159463","doi":"https://doi.org/10.4103/1658-354x.159463","is_oa":true,"landing_page_url":"https://doi.org/10.4103/1658-354x.159463","pdf_url":null,"source":{"id":"https://openalex.org/S59148946","display_name":"Saudi Journal of Anaesthesia","issn_l":"0975-3125","issn":["0975-3125","1658-354X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Journal of Anaesthesia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2265064114.pdf","grobid_xml":"https://content.openalex.org/works/W2265064114.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W125278534","https://openalex.org/W148819946","https://openalex.org/W220052254","https://openalex.org/W1505296286","https://openalex.org/W1512335984","https://openalex.org/W1584416450","https://openalex.org/W1963861883","https://openalex.org/W1966797622","https://openalex.org/W1970795195","https://openalex.org/W1973966321","https://openalex.org/W1974354715","https://openalex.org/W1978309427","https://openalex.org/W1983167835","https://openalex.org/W1995138379","https://openalex.org/W2009683113","https://openalex.org/W2010071027","https://openalex.org/W2015329095","https://openalex.org/W2016232535","https://openalex.org/W2019661924","https://openalex.org/W2022312838","https://openalex.org/W2022633926","https://openalex.org/W2023735394","https://openalex.org/W2024961993","https://openalex.org/W2025401235","https://openalex.org/W2027423445","https://openalex.org/W2034419740","https://openalex.org/W2047392303","https://openalex.org/W2048393775","https://openalex.org/W2058480753","https://openalex.org/W2059454219","https://openalex.org/W2060798677","https://openalex.org/W2075014698","https://openalex.org/W2080611634","https://openalex.org/W2081204780","https://openalex.org/W2081264669","https://openalex.org/W2116241526","https://openalex.org/W2129478213","https://openalex.org/W2133934838","https://openalex.org/W2140905120","https://openalex.org/W2153889848","https://openalex.org/W2160059429","https://openalex.org/W2161508048","https://openalex.org/W2166742691","https://openalex.org/W2280418894","https://openalex.org/W2403757711","https://openalex.org/W2409464155","https://openalex.org/W2427680149","https://openalex.org/W4233504042","https://openalex.org/W6608769737","https://openalex.org/W6695626566"],"related_works":["https://openalex.org/W2024961993","https://openalex.org/W2015329095","https://openalex.org/W2041691059","https://openalex.org/W2200617355","https://openalex.org/W2022312838","https://openalex.org/W4388517918","https://openalex.org/W2410106114","https://openalex.org/W1990091097","https://openalex.org/W2605857290","https://openalex.org/W3160281542"],"abstract_inverted_index":{"AIMS:":[0],"A":[1,54],"crossover":[2],"double-blind,":[3],"randomized":[4],"study":[5],"was":[6,101,128],"designed":[7],"to":[8,89,161,210],"explore":[9],"the":[10,114,156,220],"efficacy":[11],"of":[12,43,56,97,110,158],"2%":[13,29,76,84,90],"mepivacaine":[14,30,77,85,91,176,193,211,236,254,267,282,286],"with":[15,23,31,64,70,83],"1:100,000":[16,24,32],"adrenaline":[17,25,33],"buccal":[18,26,73,86,194,257,273,283],"infiltration":[19,27,74,87,274,284],"and":[20,75,81,146,192,226,255,278],"4%":[21,71],"articaine":[22,72,173,191,221,256],"following":[28,266,285],"inferior":[34],"alveolar":[35],"nerve":[36],"block":[37],"(IANB)":[38],"for":[39,113,149,165,203,244],"testing":[40,96,137,164],"pulp":[41,136,163,206,247,264],"anesthesia":[42,207,248,265],"mandibular":[44],"first":[45,98,115,166,204,245,262],"molar":[46,99,167,205,246,263],"teeth":[47,168],"in":[48,199,219,270],"adult":[49,59],"volunteers.":[50,271],"MATERIALS":[51],"AND":[52],"METHODS:":[53],"total":[55],"23":[57],"healthy":[58],"volunteers":[60,218],"received":[61],"two":[62,131],"regimens":[63],"at":[65,105,108],"least":[66],"1-week":[67],"apart;":[68],"one":[69],"IANB":[78,92,212,268,287],"(articaine":[79],"regimen)":[80],"another":[82],"supplemented":[88,209],"(mepivacaine":[93],"regimen).":[94],"Pulp":[95],"tooth":[100],"electronically":[102],"measured":[103],"twice":[104],"baseline,":[106],"then":[107,118],"intervals":[109],"2":[111],"min":[112,121,124,145,151,179],"10":[116,144],"min,":[117,231,233,240,242],"every":[119],"5":[120],"until":[122],"45":[123,150,178],"postinjection.":[125,152],"Anesthetic":[126],"success":[127,202],"considered":[129],"when":[130,208],"consecutive":[132],"maximal":[133],"stimulation":[134],"on":[135],"readings":[138],"without":[139],"sensation":[140],"were":[141,169],"obtained":[142],"within":[143],"continuously":[147],"sustained":[148],"RESULTS:":[153],"In":[154],"total,":[155],"number":[157],"no":[159],"sensations":[160],"maximum":[162],"significantly":[170],"higher":[171],"after":[172],"regimen":[174,222,237],"than":[175,235,281],"during":[177],"postinjection":[180],"(267":[181],"vs.":[182],"250":[183],"episodes,":[184],"respectively,":[185],"P":[186],"<":[187,250],"0.001),":[188],"however,":[189],"both":[190],"infiltrations":[195,258],"are":[196],"equally":[197],"effective":[198],"securing":[200],"anesthetic":[201],"injections":[213,269],"(P":[214,249],">":[215],"0.05).":[216],"Interestingly,":[217],"provided":[223],"faster":[224,276],"onset":[225,277],"longer":[227,279],"duration":[228,280],"(means":[229,238],"2.78":[230],"42.22":[232],"respectively)":[234,243],"4.26":[239],"40.74":[241],"0.001).":[251],"CONCLUSIONS:":[252],"Supplementary":[253],"produced":[259,275],"similar":[260],"successful":[261],"Articaine":[272],"injections.":[288]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}
