{"id":"https://openalex.org/W2264003175","doi":null,"title":"Role of Delta16HER2 splice variant in breast tumor progression and response to HER2-Targeted therapy.","display_name":"Role of Delta16HER2 splice variant in breast tumor progression and response to HER2-Targeted therapy.","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W2264003175","mag":"2264003175"},"language":"en","primary_location":{"id":"mag:2264003175","doi":null,"is_oa":false,"landing_page_url":"https://moh-it.pure.elsevier.com/en/publications/role-of-%CE%B416her2-splice-variant-in-breast-tumor-progression-and-re","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044426445","display_name":"Serenella Maria Pupa","orcid":"https://orcid.org/0000-0002-4592-6830","observed_orcids":["https://orcid.org/0000-0002-4592-6830"]},"institutions":[{"id":"https://openalex.org/I4210156707","display_name":"Fondazione IRCCS Istituto Nazionale dei Tumori","ror":"https://ror.org/05dwj7825","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210156707"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Serenella M. Pupa","raw_affiliation_strings":["Fondazione IRCCS Istituto Nazionale dei Tumori"],"raw_orcid":"https://orcid.org/0000-0002-4592-6830","affiliations":[{"raw_affiliation_string":"Fondazione IRCCS Istituto Nazionale dei Tumori","institution_ids":["https://openalex.org/I4210156707"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017342562","display_name":"Manuela Campiglio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156707","display_name":"Fondazione IRCCS Istituto Nazionale dei Tumori","ror":"https://ror.org/05dwj7825","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210156707"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Manuela Campiglio","raw_affiliation_strings":["Fondazione IRCCS Istituto Nazionale dei Tumori"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione IRCCS Istituto Nazionale dei Tumori","institution_ids":["https://openalex.org/I4210156707"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063842317","display_name":"Anna Rossini","orcid":"https://orcid.org/0000-0002-4466-4373","observed_orcids":["https://orcid.org/0000-0002-4466-4373"]},"institutions":[{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Anna Rossini","raw_affiliation_strings":["IRCCS Policlinico di Milano"],"raw_orcid":"https://orcid.org/0000-0002-4466-4373","affiliations":[{"raw_affiliation_string":"IRCCS Policlinico di Milano","institution_ids":["https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080591515","display_name":"Rosaria Orlandi","orcid":"https://orcid.org/0000-0002-0533-9041","observed_orcids":["https://orcid.org/0000-0002-0533-9041"]},"institutions":[{"id":"https://openalex.org/I4210156707","display_name":"Fondazione IRCCS Istituto Nazionale dei Tumori","ror":"https://ror.org/05dwj7825","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210156707"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosaria Orlandi","raw_affiliation_strings":["Fondazione IRCCS Istituto Nazionale dei Tumori"],"raw_orcid":"https://orcid.org/0000-0002-0533-9041","affiliations":[{"raw_affiliation_string":"Fondazione IRCCS Istituto Nazionale dei Tumori","institution_ids":["https://openalex.org/I4210156707"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056543368","display_name":"Valentina Ciravolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210156707","display_name":"Fondazione IRCCS Istituto Nazionale dei Tumori","ror":"https://ror.org/05dwj7825","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210156707"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valentina Ciravolo","raw_affiliation_strings":["Fondazione IRCCS Istituto Nazionale dei Tumori"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fondazione IRCCS Istituto Nazionale dei Tumori","institution_ids":["https://openalex.org/I4210156707"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059041711","display_name":"Augusto Roca De Amici","orcid":"https://orcid.org/0000-0002-4634-1500","observed_orcids":["https://orcid.org/0000-0002-4634-1500"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Augusto Amici","raw_affiliation_strings":["University of Camerino"],"raw_orcid":"https://orcid.org/0000-0002-4634-1500","affiliations":[{"raw_affiliation_string":"University of Camerino","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083469846","display_name":"Elda Tagliabue","orcid":"https://orcid.org/0000-0001-9877-2903","observed_orcids":["https://orcid.org/0000-0001-9877-2903"]},"institutions":[{"id":"https://openalex.org/I4210156707","display_name":"Fondazione IRCCS Istituto Nazionale dei Tumori","ror":"https://ror.org/05dwj7825","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210156707"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elda Tagliabue","raw_affiliation_strings":["Fondazione IRCCS Istituto Nazionale dei Tumori"],"raw_orcid":"https://orcid.org/0000-0001-9877-2903","affiliations":[{"raw_affiliation_string":"Fondazione IRCCS Istituto Nazionale dei Tumori","institution_ids":["https://openalex.org/I4210156707"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1621,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.54839538,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"201","last_page":"209"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8799999952316284},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.984000027179718},{"id":"https://openalex.org/keywords/her2-targeted-therapy","display_name":"HER2-targeted therapy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.46299999952316284},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.576229453086853},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.555827260017395},{"id":"https://openalex.org/C2780989783","wikidata":"https://www.wikidata.org/wiki/Q7578557","display_name":"splice","level":3,"score":0.5441367626190186},{"id":"https://openalex.org/C2781230642","wikidata":"https://www.wikidata.org/wiki/Q492646","display_name":"Targeted therapy","level":3,"score":0.49987125396728516},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.44225090742111206},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.37352609634399414},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.34682273864746094},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.25604042410850525},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2283276915550232},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22198334336280823},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.208997905254364}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2264003175","doi":null,"is_oa":false,"landing_page_url":"https://moh-it.pure.elsevier.com/en/publications/role-of-%CE%B416her2-splice-variant-in-breast-tumor-progression-and-re","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1557682778","https://openalex.org/W1597038050","https://openalex.org/W1877098097","https://openalex.org/W1986044270","https://openalex.org/W1990208211","https://openalex.org/W1990331048","https://openalex.org/W1997595809","https://openalex.org/W2007256480","https://openalex.org/W2022895967","https://openalex.org/W2024592141","https://openalex.org/W2024651005","https://openalex.org/W2037769103","https://openalex.org/W2054966044","https://openalex.org/W2074270635","https://openalex.org/W2076597279","https://openalex.org/W2086606630","https://openalex.org/W2089071484","https://openalex.org/W2091130738","https://openalex.org/W2094833794","https://openalex.org/W2097255042","https://openalex.org/W2113868669","https://openalex.org/W2131994307","https://openalex.org/W2141393790","https://openalex.org/W2159121906","https://openalex.org/W2159363679","https://openalex.org/W2165249233","https://openalex.org/W2165283019"],"related_works":["https://openalex.org/W2047885429","https://openalex.org/W6888733051","https://openalex.org/W1992959559","https://openalex.org/W2090534984","https://openalex.org/W2464721200","https://openalex.org/W7100339239","https://openalex.org/W3099460798","https://openalex.org/W2955542694","https://openalex.org/W4404962540","https://openalex.org/W2165283019"],"abstract_inverted_index":null,"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}