{"id":"https://openalex.org/W2255883548","doi":null,"title":"PLEIOTROPIC MECHANISMS OF STATIN ACTION IN ALZHEIMER'S DISEASE","display_name":"PLEIOTROPIC MECHANISMS OF STATIN ACTION IN ALZHEIMER'S DISEASE","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2255883548","mag":"2255883548"},"language":"en","primary_location":{"id":"pmh:oai:etd.ohiolink.edu:case1190669698","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1190669698","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1190669698&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=case1190669698","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1190669698&disposition=inline","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001915648","display_name":"Stephen M. Ostrowski","orcid":"https://orcid.org/0000-0002-0669-7502","observed_orcids":["https://orcid.org/0000-0002-0669-7502"]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen M. Ostrowski","raw_affiliation_strings":["Case Western Reserve University"],"raw_orcid":"https://orcid.org/0000-0002-0669-7502","affiliations":[{"raw_affiliation_string":"Case Western Reserve University","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5001915648"],"corresponding_institution_ids":["https://openalex.org/I58956616"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.24324023,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.9929999709129333},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/drug-repurposing","display_name":"drug repurposing","score":0.6380000114440918},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.7799999713897705}],"concepts":[{"id":"https://openalex.org/C2776839432","wikidata":"https://www.wikidata.org/wiki/Q954845","display_name":"Statin","level":2,"score":0.5650022625923157},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.4979410171508789},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4945323169231415},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4898030757904053},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4808395802974701},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3163946270942688},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2282104194164276},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07261517643928528},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:etd.ohiolink.edu:case1190669698","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1190669698","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1190669698&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=case1190669698","raw_type":"text"},{"id":"mag:2255883548","doi":null,"is_oa":false,"landing_page_url":"http://europepmc.org/theses/ETH/5659","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etd.ohiolink.edu:case1190669698","doi":null,"is_oa":true,"landing_page_url":"http://rave.ohiolink.edu/etdc/view?acc_num=case1190669698","pdf_url":"https://etd.ohiolink.edu/acprod/odb_etd/ws/send_file/send?accession=case1190669698&disposition=inline","source":{"id":"https://openalex.org/S4377196344","display_name":"OhioLink ETD Center (Ohio Library and Information Network)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155183","host_organization_name":"Ohio Library and Information Network","host_organization_lineage":["https://openalex.org/I4210155183"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://rave.ohiolink.edu/etdc/view?acc_num=case1190669698","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2255883548.pdf","grobid_xml":"https://content.openalex.org/works/W2255883548.grobid-xml"},"referenced_works_count":329,"referenced_works":["https://openalex.org/W17282896","https://openalex.org/W133038330","https://openalex.org/W140178960","https://openalex.org/W143025234","https://openalex.org/W156047692","https://openalex.org/W1217317373","https://openalex.org/W1447623510","https://openalex.org/W1483730857","https://openalex.org/W1483802837","https://openalex.org/W1491433568","https://openalex.org/W1492482999","https://openalex.org/W1493502680","https://openalex.org/W1498308337","https://openalex.org/W1498775324","https://openalex.org/W1500847299","https://openalex.org/W1501684770","https://openalex.org/W1503880894","https://openalex.org/W1510308646","https://openalex.org/W1516600697","https://openalex.org/W1525331105","https://openalex.org/W1528057257","https://openalex.org/W1540525572","https://openalex.org/W1545266136","https://openalex.org/W1551501233","https://openalex.org/W1562982017","https://openalex.org/W1564406238","https://openalex.org/W1565873176","https://openalex.org/W1566174201","https://openalex.org/W1594736139","https://openalex.org/W1595083713","https://openalex.org/W1596984737","https://openalex.org/W1597577233","https://openalex.org/W1605098290","https://openalex.org/W1606587171","https://openalex.org/W1606937999","https://openalex.org/W1611407165","https://openalex.org/W1644122431","https://openalex.org/W1652351875","https://openalex.org/W1663808526","https://openalex.org/W1679229316","https://openalex.org/W1790645982","https://openalex.org/W1816050387","https://openalex.org/W1860242155","https://openalex.org/W1909180518","https://openalex.org/W1911782607","https://openalex.org/W1932612562","https://openalex.org/W1961904860","https://openalex.org/W1963635405","https://openalex.org/W1963833196","https://openalex.org/W1963851577","https://openalex.org/W1964867688","https://openalex.org/W1965050626","https://openalex.org/W1965365250","https://openalex.org/W1965583284","https://openalex.org/W1967399741","https://openalex.org/W1967464880","https://openalex.org/W1967566501","https://openalex.org/W1968546119","https://openalex.org/W1968970931","https://openalex.org/W1969271586","https://openalex.org/W1973200579","https://openalex.org/W1973276273","https://openalex.org/W1973725374","https://openalex.org/W1975806945","https://openalex.org/W1976900147","https://openalex.org/W1978464661","https://openalex.org/W1978841341","https://openalex.org/W1979257234","https://openalex.org/W1980857453","https://openalex.org/W1984964878","https://openalex.org/W1985069724","https://openalex.org/W1985566364","https://openalex.org/W1986587815","https://openalex.org/W1987046654","https://openalex.org/W1990752558","https://openalex.org/W1991023072","https://openalex.org/W1991292359","https://openalex.org/W1992372212","https://openalex.org/W1992598058","https://openalex.org/W1992653365","https://openalex.org/W1992841111","https://openalex.org/W1992972153","https://openalex.org/W1993418815","https://openalex.org/W1996216953","https://openalex.org/W1996281893","https://openalex.org/W1996709343","https://openalex.org/W1997021573","https://openalex.org/W1998664054","https://openalex.org/W1998843397","https://openalex.org/W1999098901","https://openalex.org/W1999607830","https://openalex.org/W2000706612","https://openalex.org/W2000753827","https://openalex.org/W2001197606","https://openalex.org/W2001210466","https://openalex.org/W2001314906","https://openalex.org/W2001361004","https://openalex.org/W2001774934","https://openalex.org/W2003283600","https://openalex.org/W2003890494","https://openalex.org/W2004646459","https://openalex.org/W2004767178","https://openalex.org/W2004799153","https://openalex.org/W2004896472","https://openalex.org/W2006028058","https://openalex.org/W2006163959","https://openalex.org/W2006666533","https://openalex.org/W2008353883","https://openalex.org/W2009111659","https://openalex.org/W2009394026","https://openalex.org/W2011070858","https://openalex.org/W2015034968","https://openalex.org/W2015675204","https://openalex.org/W2018358250","https://openalex.org/W2019500453","https://openalex.org/W2021730434","https://openalex.org/W2022889334","https://openalex.org/W2023120740","https://openalex.org/W2023344829","https://openalex.org/W2024462254","https://openalex.org/W2024867289","https://openalex.org/W2025946388","https://openalex.org/W2027810531","https://openalex.org/W2029040938","https://openalex.org/W2029391653","https://openalex.org/W2030508474","https://openalex.org/W2030564973","https://openalex.org/W2032920422","https://openalex.org/W2033745197","https://openalex.org/W2033995139","https://openalex.org/W2034286717","https://openalex.org/W2035247878","https://openalex.org/W2035363409","https://openalex.org/W2035713311","https://openalex.org/W2036801925","https://openalex.org/W2037485198","https://openalex.org/W2037500564","https://openalex.org/W2037649918","https://openalex.org/W2038036050","https://openalex.org/W2040870583","https://openalex.org/W2041953777","https://openalex.org/W2042709174","https://openalex.org/W2042835731","https://openalex.org/W2043583138","https://openalex.org/W2044286556","https://openalex.org/W2044640674","https://openalex.org/W2046006229","https://openalex.org/W2046209489","https://openalex.org/W2046718416","https://openalex.org/W2046847750","https://openalex.org/W2047613132","https://openalex.org/W2047815983","https://openalex.org/W2048027386","https://openalex.org/W2048086967","https://openalex.org/W2048975745","https://openalex.org/W2049186585","https://openalex.org/W2049430814","https://openalex.org/W2050394333","https://openalex.org/W2053536280","https://openalex.org/W2054498733","https://openalex.org/W2055261848","https://openalex.org/W2056181922","https://openalex.org/W2057924949","https://openalex.org/W2058723245","https://openalex.org/W2058743922","https://openalex.org/W2059073594","https://openalex.org/W2060579161","https://openalex.org/W2061286464","https://openalex.org/W2061302578","https://openalex.org/W2061669829","https://openalex.org/W2061850960","https://openalex.org/W2062283435","https://openalex.org/W2062830242","https://openalex.org/W2062928074","https://openalex.org/W2063236931","https://openalex.org/W2064877246","https://openalex.org/W2066398399","https://openalex.org/W2067153744","https://openalex.org/W2067772115","https://openalex.org/W2068625958","https://openalex.org/W2071124826","https://openalex.org/W2072199290","https://openalex.org/W2072897134","https://openalex.org/W2074385612","https://openalex.org/W2074574014","https://openalex.org/W2075725519","https://openalex.org/W2075766733","https://openalex.org/W2076505784","https://openalex.org/W2076538102","https://openalex.org/W2076734975","https://openalex.org/W2077845591","https://openalex.org/W2079314942","https://openalex.org/W2079997045","https://openalex.org/W2080563648","https://openalex.org/W2081182167","https://openalex.org/W2081416526","https://openalex.org/W2081586704","https://openalex.org/W2081881251","https://openalex.org/W2081998222","https://openalex.org/W2083633251","https://openalex.org/W2084015178","https://openalex.org/W2084292803","https://openalex.org/W2084491557","https://openalex.org/W2084604930","https://openalex.org/W2085728170","https://openalex.org/W2087524018","https://openalex.org/W2087969945","https://openalex.org/W2089906643","https://openalex.org/W2090081205","https://openalex.org/W2090702802","https://openalex.org/W2091557924","https://openalex.org/W2093610690","https://openalex.org/W2094303671","https://openalex.org/W2094411486","https://openalex.org/W2094841812","https://openalex.org/W2095534953","https://openalex.org/W2096012124","https://openalex.org/W2097296286","https://openalex.org/W2098460507","https://openalex.org/W2098536076","https://openalex.org/W2098806204","https://openalex.org/W2098946775","https://openalex.org/W2099556509","https://openalex.org/W2100610042","https://openalex.org/W2101077392","https://openalex.org/W2101176536","https://openalex.org/W2101256091","https://openalex.org/W2102459023","https://openalex.org/W2102492191","https://openalex.org/W2103496509","https://openalex.org/W2103856558","https://openalex.org/W2104227586","https://openalex.org/W2105632027","https://openalex.org/W2106009748","https://openalex.org/W2106192181","https://openalex.org/W2107288853","https://openalex.org/W2108298524","https://openalex.org/W2108326377","https://openalex.org/W2108689038","https://openalex.org/W2110106971","https://openalex.org/W2111119128","https://openalex.org/W2111778006","https://openalex.org/W2112494618","https://openalex.org/W2112522119","https://openalex.org/W2112698709","https://openalex.org/W2113690827","https://openalex.org/W2114806174","https://openalex.org/W2116423228","https://openalex.org/W2116784956","https://openalex.org/W2121261412","https://openalex.org/W2121448546","https://openalex.org/W2122027285","https://openalex.org/W2122599308","https://openalex.org/W2123941817","https://openalex.org/W2124308710","https://openalex.org/W2125483042","https://openalex.org/W2126108937","https://openalex.org/W2128195111","https://openalex.org/W2128479394","https://openalex.org/W2128635872","https://openalex.org/W2128690136","https://openalex.org/W2128706310","https://openalex.org/W2129960297","https://openalex.org/W2130552816","https://openalex.org/W2131200617","https://openalex.org/W2131963133","https://openalex.org/W2132810311","https://openalex.org/W2133019124","https://openalex.org/W2133362776","https://openalex.org/W2133782231","https://openalex.org/W2133898534","https://openalex.org/W2134073766","https://openalex.org/W2135612359","https://openalex.org/W2136622296","https://openalex.org/W2136647702","https://openalex.org/W2137760199","https://openalex.org/W2138769898","https://openalex.org/W2139582633","https://openalex.org/W2139825669","https://openalex.org/W2140139281","https://openalex.org/W2140272887","https://openalex.org/W2140298351","https://openalex.org/W2140631432","https://openalex.org/W2145123193","https://openalex.org/W2145653235","https://openalex.org/W2145859941","https://openalex.org/W2146072223","https://openalex.org/W2147354849","https://openalex.org/W2148152028","https://openalex.org/W2148463229","https://openalex.org/W2150565253","https://openalex.org/W2151099771","https://openalex.org/W2151588652","https://openalex.org/W2151602225","https://openalex.org/W2152524859","https://openalex.org/W2153716000","https://openalex.org/W2153723509","https://openalex.org/W2153825396","https://openalex.org/W2154441086","https://openalex.org/W2155518349","https://openalex.org/W2156654096","https://openalex.org/W2156962646","https://openalex.org/W2158157260","https://openalex.org/W2159529587","https://openalex.org/W2160152341","https://openalex.org/W2160524771","https://openalex.org/W2162676210","https://openalex.org/W2162815565","https://openalex.org/W2163417125","https://openalex.org/W2164208610","https://openalex.org/W2164537715","https://openalex.org/W2166336042","https://openalex.org/W2166390550","https://openalex.org/W2166564135","https://openalex.org/W2167215352","https://openalex.org/W2169555689","https://openalex.org/W2170644095","https://openalex.org/W2176744910","https://openalex.org/W2186601255","https://openalex.org/W2289018119","https://openalex.org/W2322095705","https://openalex.org/W2323918049","https://openalex.org/W2357420288","https://openalex.org/W2403710204","https://openalex.org/W2408810695","https://openalex.org/W2419789578","https://openalex.org/W2473253444","https://openalex.org/W3141682137","https://openalex.org/W4252526962"],"related_works":["https://openalex.org/W2086695952","https://openalex.org/W4255244940","https://openalex.org/W4233954616","https://openalex.org/W2012073271","https://openalex.org/W4220911621","https://openalex.org/W2018568348","https://openalex.org/W7109169427","https://openalex.org/W4234645906","https://openalex.org/W1989112928","https://openalex.org/W6903878472"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
