{"id":"https://openalex.org/W22536586","doi":null,"title":"The association of body weight, body fatness and body fat distribution with osteoarthritis of the knee: data from the Baltimore Longitudinal Study of Aging.","display_name":"The association of body weight, body fatness and body fat distribution with osteoarthritis of the knee: data from the Baltimore Longitudinal Study of Aging.","publication_year":1995,"publication_date":"1995-03-01","ids":{"openalex":"https://openalex.org/W22536586","mag":"22536586","pmid":"https://pubmed.ncbi.nlm.nih.gov/7783067"},"language":"en","primary_location":{"id":"pmid:7783067","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7783067","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of rheumatology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109317140","display_name":"Hochberg Mc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M C Hochberg","raw_affiliation_strings":["Department of Medicine, University of Maryland, School of Medicine, Baltimore, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Maryland, School of Medicine, Baltimore, USA","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013409436","display_name":"Margaret Lethbridge\u2010\u00c7ejku","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Lethbridge-Cejku","raw_affiliation_strings":["University of Maryland, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Maryland, Baltimore","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":null,"display_name":"W W Scott","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W W Scott","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074040275","display_name":"R Reichle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R Reichle","raw_affiliation_strings":["University of Maryland, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Maryland, Baltimore","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033815803","display_name":"Plato Cc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C C Plato","raw_affiliation_strings":["University of Maryland, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Maryland, Baltimore","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108243622","display_name":"Tobin Jd","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J D Tobin","raw_affiliation_strings":["University of Maryland, Baltimore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Maryland, Baltimore","institution_ids":["https://openalex.org/I126744593"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.9148,"has_fulltext":false,"cited_by_count":269,"citation_normalized_percentile":{"value":0.96728819,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"22","issue":"3","first_page":"488","last_page":"93"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9639000296592712,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11018","display_name":"Lower Extremity Biomechanics and Pathologies","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/knee-osteoarthritis","display_name":"knee osteoarthritis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/body-weight","display_name":"body weight","score":0.8019999861717224},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.6869999766349792},{"id":"https://openalex.org/keywords/body-fat-distribution","display_name":"body fat distribution","score":0.9549999833106995},{"id":"https://openalex.org/keywords/waist-to-hip-ratio","display_name":"waist-to-hip ratio","score":0.8159999847412109},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.9589999914169312},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.7630000114440918},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8169999718666077},{"id":"https://openalex.org/keywords/mechanical-risk-factors","display_name":"mechanical risk factors","score":0.7179999947547913},{"id":"https://openalex.org/keywords/baltimore-longitudinal-study-of-aging","display_name":"Baltimore Longitudinal Study of Aging","score":0.8500000238418579}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9137037396430969},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.878655195236206},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6819847226142883},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.6690316796302795},{"id":"https://openalex.org/C2776193436","wikidata":"https://www.wikidata.org/wiki/Q236232","display_name":"Waist","level":3,"score":0.6542823314666748},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6358548402786255},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5724937915802002},{"id":"https://openalex.org/C111214947","wikidata":"https://www.wikidata.org/wiki/Q22907290","display_name":"Classification of obesity","level":4,"score":0.5104178786277771},{"id":"https://openalex.org/C2780005051","wikidata":"https://www.wikidata.org/wiki/Q797258","display_name":"Body fat percentage","level":3,"score":0.4781825840473175},{"id":"https://openalex.org/C33997684","wikidata":"https://www.wikidata.org/wiki/Q876152","display_name":"Waist\u2013hip ratio","level":4,"score":0.445973664522171},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3573340177536011},{"id":"https://openalex.org/C2993503589","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Fat mass","level":3,"score":0.14773160219192505},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07843118906021118},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000273","descriptor_name":"Adipose Tissue","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001824","descriptor_name":"Body Constitution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007719","descriptor_name":"Knee Joint","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010003","descriptor_name":"Osteoarthritis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7783067","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7783067","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of rheumatology","raw_type":"Journal Article"},{"id":"mag:22536586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7783067","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2242767875","https://openalex.org/W1696739609","https://openalex.org/W2001790018","https://openalex.org/W2799325491","https://openalex.org/W2888489578","https://openalex.org/W2344773560","https://openalex.org/W2019576201","https://openalex.org/W2056417961","https://openalex.org/W2550678129","https://openalex.org/W4391107472"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"examine":[2],"the":[3,18,44,70,124,144,167,188],"association":[4,189],"of":[5,17,30,48,57,63,102,115,127,135,149,157,170,177,190,235],"body":[6,8,11,77,81,84,103,117,128,151,184,192,216],"weight,":[7],"fatness,":[9],"and":[10,28,34,41,83,90,121,138,146,160,164,194,202,223,230],"fat":[12,85,152,193],"distribution":[13],"with":[14,92,197,220],"osteoarthritis":[15],"(OA)":[16],"knee.":[19],"METHODS:":[20],"Bilateral":[21],"standing":[22],"knee":[23,94,140,162,179,198,225],"radiographs,":[24],"taken":[25],"between":[26],"1985":[27],"1991,":[29],"465":[31],"Caucasian":[32,36],"men":[33,89,122,165],"275":[35],"women":[37,91,107,120,142,201],"subjects":[38],"aged":[39],"40":[40],"above":[42],"in":[43,123,143,166,200,227],"Baltimore":[45],"Longitudinal":[46],"Study":[47],"Aging":[49],"were":[50],"read":[51],"by":[52],"one":[53],"investigator":[54],"for":[55,183],"grade":[56],"OA":[58,95,199,226],"using":[59],"Kellgren-Lawrence":[60],"scales.":[61],"Measures":[62],"obesity,":[64],"assessed":[65],"at":[66],"same":[67],"visit":[68],"as":[69,237],"last":[71],"radiograph":[72],"during":[73],"this":[74,244],"interval,":[75],"included":[76],"mass":[78,104,129,185],"index,":[79,105,186],"percent":[80,116,150,191],"fat,":[82],"distribution.":[86],"RESULTS:":[87],"Both":[88,119],"definite":[93,137,159,222],"had":[96,109,131,153,173],"higher":[97,110],"age":[98,111],"adjusted":[99,112],"mean":[100,113],"levels":[101,114],"while":[106],"only":[108],"fat.":[118],"highest":[125,147,168],"tertile":[126,148,169],"index":[130],"significantly":[132,154,174],"increased":[133,155,175],"odds":[134,156,176],"both":[136,158,221,228],"bilateral":[139,161,178,224],"OA;":[141],"middle":[145],"OA,":[163],"waist-hip":[171,195],"ratio":[172,196],"OA.":[180],"After":[181],"adjusting":[182],"however,":[187],"men,":[203],"respectively,":[204],"was":[205],"no":[206],"longer":[207],"significant.":[208],"CONCLUSION:":[209],"These":[210],"data":[211],"further":[212],"extend":[213],"observations":[214],"that":[215],"weight":[217],"is":[218],"associated":[219],"sexes,":[229],"support":[231],"a":[232],"stronger":[233],"contribution":[234],"mechanical":[236],"opposed":[238],"to":[239,242],"systemic":[240],"factors":[241],"explain":[243],"association.":[245]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":19},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":9}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}