{"id":"https://openalex.org/W224947396","doi":"https://doi.org/10.1007/0-387-24180-9_15","title":"Ontogeny of Lagerhans Cells and Graft Versus Host Disease","display_name":"Ontogeny of Lagerhans Cells and Graft Versus Host Disease","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W224947396","doi":"https://doi.org/10.1007/0-387-24180-9_15","mag":"224947396","pmid":"https://pubmed.ncbi.nlm.nih.gov/15932027"},"language":"en","primary_location":{"id":"doi:10.1007/0-387-24180-9_15","doi":"https://doi.org/10.1007/0-387-24180-9_15","is_oa":false,"landing_page_url":"https://doi.org/10.1007/0-387-24180-9_15","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2489834556","display_name":"Mechanisms of Lymphocyte Activation and Immune Regulation X"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070354041","display_name":"Miriam M\u00e9rad","orcid":"https://orcid.org/0000-0002-4481-7827","observed_orcids":["https://orcid.org/0000-0002-4481-7827"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Miriam Merad","raw_affiliation_strings":["Center for Gene Therapy, Department of Medicine, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA","Mount Sinai School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Gene Therapy, Department of Medicine, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA","institution_ids":["https://openalex.org/I98704320"]},{"raw_affiliation_string":"Mount Sinai School of Medicine","institution_ids":["https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070354041"],"corresponding_institution_ids":["https://openalex.org/I98704320"],"apc_list":null,"apc_paid":null,"fwci":4.3455,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.90356394,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"560","issue":null,"first_page":"115","last_page":"123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.6563000082969666,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.6563000082969666,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.29739999771118164,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.020400000736117363,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/langerhans-cells","display_name":"Langerhans cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cutaneous-graft-versus-host-disease","display_name":"cutaneous graft-versus-host disease","score":0.8339999914169312},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.8100000023841858},{"id":"https://openalex.org/keywords/allogeneic-bone-marrow-transplantation","display_name":"allogeneic bone marrow transplantation","score":0.9020000100135803},{"id":"https://openalex.org/keywords/antigen-presentation","display_name":"antigen presentation","score":0.6899999976158142},{"id":"https://openalex.org/keywords/donor-t-cell-activation","display_name":"donor T cell activation","score":0.6859999895095825},{"id":"https://openalex.org/keywords/epidermis","display_name":"epidermis","score":0.7179999947547913},{"id":"https://openalex.org/keywords/skin-immunity","display_name":"skin immunity","score":0.6610000133514404}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6345714330673218},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6145318150520325},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5332208871841431},{"id":"https://openalex.org/C2776458125","wikidata":"https://www.wikidata.org/wiki/Q1827343","display_name":"Epidermis (zoology)","level":2,"score":0.5193865895271301},{"id":"https://openalex.org/C2779972918","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft-versus-host disease","level":3,"score":0.5120937824249268},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.5085185766220093},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.45529085397720337},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4524305462837219},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4419674575328827},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.43478095531463623},{"id":"https://openalex.org/C2778170410","wikidata":"https://www.wikidata.org/wiki/Q506253","display_name":"Dendritic cell","level":3,"score":0.416761189699173},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4110383987426758},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.36545801162719727},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33112335205078125},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.29948097467422485},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21191558241844177},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1058228611946106},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.09464308619499207}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007801","descriptor_name":"Langerhans Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007801","descriptor_name":"Langerhans Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D014466","descriptor_name":"Ultraviolet Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018925","descriptor_name":"Chemokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/0-387-24180-9_15","doi":"https://doi.org/10.1007/0-387-24180-9_15","is_oa":false,"landing_page_url":"https://doi.org/10.1007/0-387-24180-9_15","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},{"id":"pmid:15932027","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15932027","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in experimental medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":77,"referenced_works":["https://openalex.org/W95626283","https://openalex.org/W97158386","https://openalex.org/W142150519","https://openalex.org/W1500757144","https://openalex.org/W1504310442","https://openalex.org/W1557751646","https://openalex.org/W1599864954","https://openalex.org/W1600921312","https://openalex.org/W1810563907","https://openalex.org/W1964118772","https://openalex.org/W1972817398","https://openalex.org/W1975442047","https://openalex.org/W1975463463","https://openalex.org/W1992613163","https://openalex.org/W1994942368","https://openalex.org/W1999345400","https://openalex.org/W2003673339","https://openalex.org/W2004722629","https://openalex.org/W2007321497","https://openalex.org/W2008661167","https://openalex.org/W2010951033","https://openalex.org/W2012940838","https://openalex.org/W2013888332","https://openalex.org/W2015954946","https://openalex.org/W2017372035","https://openalex.org/W2024352457","https://openalex.org/W2024599128","https://openalex.org/W2024949461","https://openalex.org/W2025859796","https://openalex.org/W2026578487","https://openalex.org/W2027409800","https://openalex.org/W2032494769","https://openalex.org/W2033164429","https://openalex.org/W2041438140","https://openalex.org/W2047736625","https://openalex.org/W2052071946","https://openalex.org/W2053583666","https://openalex.org/W2054846695","https://openalex.org/W2056461632","https://openalex.org/W2056895818","https://openalex.org/W2064681773","https://openalex.org/W2067564880","https://openalex.org/W2070515735","https://openalex.org/W2071066932","https://openalex.org/W2078581257","https://openalex.org/W2082816999","https://openalex.org/W2085530853","https://openalex.org/W2086387065","https://openalex.org/W2088024377","https://openalex.org/W2088764241","https://openalex.org/W2090786449","https://openalex.org/W2096152012","https://openalex.org/W2099675490","https://openalex.org/W2103384599","https://openalex.org/W2111220263","https://openalex.org/W2114521050","https://openalex.org/W2116134009","https://openalex.org/W2122509690","https://openalex.org/W2125347897","https://openalex.org/W2131761283","https://openalex.org/W2134326405","https://openalex.org/W2139507768","https://openalex.org/W2152414109","https://openalex.org/W2154463442","https://openalex.org/W2155792963","https://openalex.org/W2157796499","https://openalex.org/W2161354474","https://openalex.org/W2165299403","https://openalex.org/W2169672731","https://openalex.org/W2182195177","https://openalex.org/W2185201488","https://openalex.org/W2402533012","https://openalex.org/W2404928744","https://openalex.org/W2916269123","https://openalex.org/W4236572065","https://openalex.org/W4256235973","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W1984275656","https://openalex.org/W2029470950","https://openalex.org/W906598096","https://openalex.org/W1979185708","https://openalex.org/W2530570872","https://openalex.org/W2564406354","https://openalex.org/W2060009502","https://openalex.org/W2095838137","https://openalex.org/W4205884397","https://openalex.org/W2574662994"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}