{"id":"https://openalex.org/W2248672482","doi":null,"title":"A Multifactor Analysis of Polymicrobial Wound Pathogenic Biofilms Using Conventional Assays, Nanoscale Imaging, and a Microfluidic Platform","display_name":"A Multifactor Analysis of Polymicrobial Wound Pathogenic Biofilms Using Conventional Assays, Nanoscale Imaging, and a Microfluidic Platform","publication_year":2014,"publication_date":"2014-12-24","ids":{"openalex":"https://openalex.org/W2248672482","mag":"2248672482"},"language":"en","primary_location":{"id":"pmh:oai:atrium.lib.uoguelph.ca:10214/8630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10214/8630","pdf_url":"http://atrium.lib.uoguelph.ca/xmlui/bitstream/10214/8630/3/Birkenhauer_Eric_201412_MSc.pdf","source":{"id":"https://openalex.org/S4306401043","display_name":"The Atrium (University of Guelph)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79817857","host_organization_name":"University of Guelph","host_organization_lineage":["https://openalex.org/I79817857"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://atrium.lib.uoguelph.ca/xmlui/bitstream/10214/8630/3/Birkenhauer_Eric_201412_MSc.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049777687","display_name":"Eric Birkenhauer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Eric Birkenhauer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5049777687"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multispecies-biofilms","display_name":"polymicrobial biofilms","score":0.8849999904632568},{"id":"https://openalex.org/keywords/chronic-wounds","display_name":"chronic wounds","score":0.609000027179718},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9940000176429749},{"id":"https://openalex.org/keywords/methicillin-resistant-staphylococcus-aureus","display_name":"methicillin-resistant Staphylococcus aureus","score":0.9909999966621399},{"id":"https://openalex.org/keywords/microbial-competition","display_name":"microbial competition","score":0.6380000114440918},{"id":"https://openalex.org/keywords/biofilm-biomass","display_name":"biofilm biomass","score":0.9229999780654907},{"id":"https://openalex.org/keywords/kelvin-probe-force-microscopy","display_name":"Kelvin probe force microscopy","score":0.890999972820282},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.8330000042915344},{"id":"https://openalex.org/keywords/wound-infection","display_name":"wound infection","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.6659854650497437},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.5324498414993286},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5239593982696533},{"id":"https://openalex.org/C45206210","wikidata":"https://www.wikidata.org/wiki/Q2415817","display_name":"Nanoscopic scale","level":2,"score":0.4661945402622223},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3693157434463501},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.36549893021583557},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.35883235931396484},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3405620753765106},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2373712658882141},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09020882844924927},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:atrium.lib.uoguelph.ca:10214/8630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10214/8630","pdf_url":"http://atrium.lib.uoguelph.ca/xmlui/bitstream/10214/8630/3/Birkenhauer_Eric_201412_MSc.pdf","source":{"id":"https://openalex.org/S4306401043","display_name":"The Atrium (University of Guelph)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79817857","host_organization_name":"University of Guelph","host_organization_lineage":["https://openalex.org/I79817857"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2248672482","doi":null,"is_oa":false,"landing_page_url":"https://atrium.lib.uoguelph.ca/xmlui/handle/10214/8630","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:atrium.lib.uoguelph.ca:10214/8630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10214/8630","pdf_url":"http://atrium.lib.uoguelph.ca/xmlui/bitstream/10214/8630/3/Birkenhauer_Eric_201412_MSc.pdf","source":{"id":"https://openalex.org/S4306401043","display_name":"The Atrium (University of Guelph)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79817857","host_organization_name":"University of Guelph","host_organization_lineage":["https://openalex.org/I79817857"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2248672482.pdf","grobid_xml":"https://content.openalex.org/works/W2248672482.grobid-xml"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W1497457526","https://openalex.org/W1523052701","https://openalex.org/W1532788636","https://openalex.org/W1537265286","https://openalex.org/W1577305427","https://openalex.org/W1831712802","https://openalex.org/W1882424553","https://openalex.org/W1892190732","https://openalex.org/W1963567444","https://openalex.org/W1966090583","https://openalex.org/W1967018406","https://openalex.org/W1967410235","https://openalex.org/W1970294462","https://openalex.org/W1972344874","https://openalex.org/W1972714867","https://openalex.org/W1973691193","https://openalex.org/W1974603116","https://openalex.org/W1974941450","https://openalex.org/W1978641850","https://openalex.org/W1979358562","https://openalex.org/W1979803376","https://openalex.org/W1981264689","https://openalex.org/W1984590702","https://openalex.org/W1985349190","https://openalex.org/W1985986963","https://openalex.org/W1989452115","https://openalex.org/W1995676605","https://openalex.org/W1997093480","https://openalex.org/W1999425652","https://openalex.org/W2000522161","https://openalex.org/W2002838338","https://openalex.org/W2004325260","https://openalex.org/W2008009348","https://openalex.org/W2010779233","https://openalex.org/W2012128059","https://openalex.org/W2015981897","https://openalex.org/W2016158447","https://openalex.org/W2017345593","https://openalex.org/W2021429998","https://openalex.org/W2021848675","https://openalex.org/W2028272831","https://openalex.org/W2029043977","https://openalex.org/W2029776332","https://openalex.org/W2032624491","https://openalex.org/W2032936079","https://openalex.org/W2038334406","https://openalex.org/W2041363846","https://openalex.org/W2042820491","https://openalex.org/W2044015123","https://openalex.org/W2044857579","https://openalex.org/W2047093090","https://openalex.org/W2048602281","https://openalex.org/W2048631210","https://openalex.org/W2053110759","https://openalex.org/W2061403746","https://openalex.org/W2062457723","https://openalex.org/W2063356483","https://openalex.org/W2065059072","https://openalex.org/W2067189227","https://openalex.org/W2067612722","https://openalex.org/W2068225897","https://openalex.org/W2068607751","https://openalex.org/W2071912459","https://openalex.org/W2075933756","https://openalex.org/W2085304745","https://openalex.org/W2085887522","https://openalex.org/W2087771681","https://openalex.org/W2089613599","https://openalex.org/W2094264280","https://openalex.org/W2096341513","https://openalex.org/W2105173502","https://openalex.org/W2106107840","https://openalex.org/W2107941718","https://openalex.org/W2111519259","https://openalex.org/W2112713239","https://openalex.org/W2113882505","https://openalex.org/W2120839774","https://openalex.org/W2124394298","https://openalex.org/W2125510352","https://openalex.org/W2127511446","https://openalex.org/W2133838892","https://openalex.org/W2143732800","https://openalex.org/W2151217692","https://openalex.org/W2154661271","https://openalex.org/W2155827766","https://openalex.org/W2157057697","https://openalex.org/W2157177676","https://openalex.org/W2158246014","https://openalex.org/W2165337806","https://openalex.org/W2166698592","https://openalex.org/W2169808625","https://openalex.org/W2412866415","https://openalex.org/W3150248096"],"related_works":["https://openalex.org/W4281770006","https://openalex.org/W3037491291","https://openalex.org/W7124150805","https://openalex.org/W1959698936","https://openalex.org/W3157287104","https://openalex.org/W2752027350","https://openalex.org/W3167638683","https://openalex.org/W4296280970","https://openalex.org/W4226177263","https://openalex.org/W2002838338"],"abstract_inverted_index":{"This":[0],"thesis":[1],"investigates":[2],"Pseudomonas":[3],"aeruginosa":[4,18,64,71],"and":[5,19,37,46,65,125,145],"methicillin-resistant":[6],"Staphylococcus":[7],"aureus":[8],"(MRSA)":[9],"pathogenic":[10],"wound":[11,26,137],"biofilms":[12,77],"through":[13],"a":[14,131,143],"multifactor":[15],"analysis.":[16],"P.":[17,63,70,151],"MRSA":[20,66],"are":[21,30,42,53],"commonly":[22],"found":[23],"in":[24],"chronic":[25],"biofilms.":[27],"Chronic":[28],"wounds":[29],"of":[31,90,113,150],"major":[32],"concern":[33],"to":[34,44,80,94,108,122],"healthcare":[35],"systems":[36],"medical":[38],"professionals":[39],"as":[40,142],"they":[41],"costly":[43],"treat":[45],"often":[47],"become":[48],"infected.":[49],"Co-culture":[50,76],"biofilm":[51,83],"studies":[52],"relatively":[54],"novel.":[55],"Quantitative":[56],"results":[57],"(P":[58],"<":[59],"0.05)":[60],"show":[61],"that":[62,103,136],"act":[67],"competitively,":[68],"with":[69],"being":[72],"the":[73,147],"dominant":[74],"species.":[75],"were":[78],"shown":[79],"produce":[81],"less":[82],"biomass":[84],"than":[85],"their":[86],"mono-culture":[87],"counterparts.":[88],"Examination":[89],"microbial":[91],"adhesion":[92,107,121],"kinetics":[93],"various":[95],"material-surfaces":[96,124],"using":[97,130],"Kelvin":[98],"probe":[99],"force":[100],"microscopy":[101],"revealed":[102,117],"both":[104],"microorganisms":[105],"preferred":[106],"positively":[109],"charged":[110],"surfaces.":[111],"Measurements":[112],"cell":[114],"surface":[115],"potentials":[116],"significant":[118],"changes":[119],"upon":[120],"different":[123],"from":[126],"co-culturing.":[127],"Chemotaxis":[128],"experiments":[129],"nanoporous":[132],"microfluidic":[133],"platform":[134],"showed":[135],"relevant":[138],"cytokine":[139],"VEGF":[140],"acts":[141],"chemoattractant":[144],"influences":[146],"swimming":[148],"dynamics":[149],"aeruginosa.":[152]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}
