{"id":"https://openalex.org/W2247170744","doi":null,"title":"The role of orlistat in weight management.","display_name":"The role of orlistat in weight management.","publication_year":2001,"publication_date":"2001-04-01","ids":{"openalex":"https://openalex.org/W2247170744","mag":"2247170744","pmid":"https://pubmed.ncbi.nlm.nih.gov/11355219"},"language":"en","primary_location":{"id":"pmid:11355219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11355219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Australian family physician","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110163994","display_name":"S. J. Marks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801350665","display_name":"Monash Medical Centre","ror":"https://ror.org/036s9kg65","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2801350665","https://openalex.org/I4210121067"]},{"id":"https://openalex.org/I4210121067","display_name":"Monash Health","ror":"https://ror.org/02t1bej08","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I4210121067"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"S Marks","raw_affiliation_strings":["Monash Medical Centre, Melbourne, Victoria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Monash Medical Centre, Melbourne, Victoria","institution_ids":["https://openalex.org/I2801350665","https://openalex.org/I4210121067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110163994"],"corresponding_institution_ids":["https://openalex.org/I2801350665","https://openalex.org/I4210121067"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.24115075,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"30","issue":"4","first_page":"335","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10010","display_name":"Obesity, Physical Activity, Diet","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/orlistat","display_name":"orlistat","score":1.0},{"id":"https://openalex.org/keywords/weight-management","display_name":"weight management","score":0.8730000257492065},{"id":"https://openalex.org/keywords/anti-obesity-drugs","display_name":"anti-obesity drugs","score":0.8429999947547913},{"id":"https://openalex.org/keywords/fat-absorption-inhibition","display_name":"fat absorption inhibition","score":0.8619999885559082},{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.9269999861717224},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.6240000128746033},{"id":"https://openalex.org/keywords/cholesterol-lowering","display_name":"cholesterol lowering","score":0.6370000243186951},{"id":"https://openalex.org/keywords/low-fat-diet","display_name":"low-fat diet","score":0.7229999899864197},{"id":"https://openalex.org/keywords/adverse-effects","display_name":"adverse effects","score":0.6959999799728394},{"id":"https://openalex.org/keywords/dietary-change","display_name":"dietary change","score":0.5950000286102295},{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.9810000061988831}],"concepts":[{"id":"https://openalex.org/C2780780548","wikidata":"https://www.wikidata.org/wiki/Q424163","display_name":"Orlistat","level":4,"score":0.9978744983673096},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.863838791847229},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5728151798248291},{"id":"https://openalex.org/C34320749","wikidata":"https://www.wikidata.org/wiki/Q17087302","display_name":"Weight management","level":4,"score":0.5356414318084717},{"id":"https://openalex.org/C2779952866","wikidata":"https://www.wikidata.org/wiki/Q6746705","display_name":"Management of obesity","level":4,"score":0.531236469745636},{"id":"https://openalex.org/C75908981","wikidata":"https://www.wikidata.org/wiki/Q28578","display_name":"Appetite","level":2,"score":0.52692711353302},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4633524715900421},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.46211081743240356},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3302030861377716}],"mesh":[{"descriptor_ui":"D000077403","descriptor_name":"Orlistat","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001361","descriptor_name":"Avitaminosis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007783","descriptor_name":"Lactones","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007783","descriptor_name":"Lactones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019440","descriptor_name":"Anti-Obesity Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D019440","descriptor_name":"Anti-Obesity Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:11355219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11355219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Australian family physician","raw_type":"Journal Article"},{"id":"mag:2247170744","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11355219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9907000064849854}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2066580118","https://openalex.org/W2041294995","https://openalex.org/W2058573970","https://openalex.org/W2052766793","https://openalex.org/W4301502981","https://openalex.org/W1929262177","https://openalex.org/W1488055325","https://openalex.org/W1999047125","https://openalex.org/W6885050120","https://openalex.org/W4299641013"],"abstract_inverted_index":{"BACKGROUND:":[0],"Most":[1],"antiobesity":[2],"drugs":[3,21],"act":[4],"centrally":[5],"to":[6,44,65],"reduce":[7],"appetite":[8],"or":[9],"increase":[10],"satiety.":[11],"Orlistat":[12,53],"is":[13,54],"the":[14,36],"first":[15],"in":[16,28,48,57,74,78],"a":[17,24,79,102],"new":[18],"class":[19],"of":[20,41],"targeted":[22],"at":[23],"single":[25],"dietary":[26,31,66],"component,":[27],"this":[29],"case":[30],"fat.":[32],"OBJECTIVE:":[33],"To":[34],"review":[35],"clinical":[37],"actions":[38],"and":[39,43,68,85,93],"efficacy":[40],"orlistat":[42],"discuss":[45],"its":[46],"place":[47],"overall":[49],"weight":[50,60,83],"management.":[51],"DISCUSSION:":[52],"best":[55],"used":[56],"long":[58],"term":[59],"management":[61],"as":[62,90],"an":[63],"adjunct":[64],"modification":[67],"increased":[69],"physical":[70],"activity.":[71],"The":[72],"reduction":[73,84],"fat":[75,104],"absorption":[76],"results":[77],"slow":[80],"but":[81],"sustained":[82],"improved":[86],"metabolic":[87],"parameters":[88],"such":[89],"reduced":[91],"total,":[92],"LDL":[94],"cholesterol.":[95],"Side":[96],"effects":[97],"are":[98],"minimised":[99],"by":[100],"maintaining":[101],"low":[103],"diet.":[105]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}