{"id":"https://openalex.org/W2238727170","doi":null,"title":"Studies on hemodynamics and coagulation in neuroanesthesia","display_name":"Studies on hemodynamics and coagulation in neuroanesthesia","publication_year":2015,"publication_date":"2015-11-06","ids":{"openalex":"https://openalex.org/W2238727170","mag":"2238727170"},"language":"en","primary_location":{"id":"pmh:oai:helda.helsinki.fi:10138/156630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/156630","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10138/156630","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043281201","display_name":"Teemu Luostarinen","orcid":"https://orcid.org/0000-0001-7482-4166","observed_orcids":["https://orcid.org/0000-0001-7482-4166"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Teemu Luostarinen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7482-4166","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5043281201"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.38089999556541443,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.38089999556541443,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications","score":0.22110000252723694,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.11490000039339066,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroanesthesia","display_name":"neuroanesthesia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cerebral-perfusion-pressure","display_name":"cerebral perfusion pressure","score":0.9599999785423279},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":1.0},{"id":"https://openalex.org/keywords/blood-coagulation","display_name":"coagulation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/intraoperative-transfusion","display_name":"intraoperative blood transfusion","score":0.7200000286102295},{"id":"https://openalex.org/keywords/ruptured-intracranial-aneurysm","display_name":"ruptured intracranial aneurysm","score":0.9340000152587891},{"id":"https://openalex.org/keywords/subarachnoid-hemorrhage","display_name":"subarachnoid hemorrhage","score":0.9610000252723694},{"id":"https://openalex.org/keywords/fresh-frozen-plasma","display_name":"fresh frozen plasma","score":0.9660000205039978},{"id":"https://openalex.org/keywords/hypertonic-saline","display_name":"hypertonic saline","score":0.9750000238418579},{"id":"https://openalex.org/keywords/mannitol","display_name":"mannitol","score":0.9879999756813049},{"id":"https://openalex.org/keywords/intracranial-pressure","display_name":"intracranial pressure","score":0.906000018119812},{"id":"https://openalex.org/keywords/end-tidal-carbon-dioxide","display_name":"end-tidal carbon dioxide","score":0.9269999861717224},{"id":"https://openalex.org/keywords/paco2","display_name":"PaCO2","score":0.8669999837875366},{"id":"https://openalex.org/keywords/arterial-blood-gas","display_name":"arterial blood gases","score":0.8560000061988831},{"id":"https://openalex.org/keywords/prone-position","display_name":"prone position","score":0.5479999780654907},{"id":"https://openalex.org/keywords/goal-directed-fluid-therapy","display_name":"goal-directed fluid therapy","score":0.7699999809265137},{"id":"https://openalex.org/keywords/hydroxyethyl-starch","display_name":"hydroxyethyl starch","score":0.9589999914169312},{"id":"https://openalex.org/keywords/ringer-s-acetate","display_name":"Ringer's acetate","score":0.878000020980835}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9052056074142456},{"id":"https://openalex.org/C2776848632","wikidata":"https://www.wikidata.org/wiki/Q853463","display_name":"Clipping (morphology)","level":2,"score":0.8675165176391602},{"id":"https://openalex.org/C2776098176","wikidata":"https://www.wikidata.org/wiki/Q189389","display_name":"Aneurysm","level":2,"score":0.8451231122016907},{"id":"https://openalex.org/C2776991684","wikidata":"https://www.wikidata.org/wiki/Q190012","display_name":"Adenosine","level":2,"score":0.5846433639526367},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5167045593261719},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5133313536643982},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27811890840530396},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:helda.helsinki.fi:10138/156630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/156630","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoralThesis"},{"id":"mag:2238727170","doi":null,"is_oa":false,"landing_page_url":"https://helda.helsinki.fi/bitstream/10138/156630/1/studieso.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:helda.helsinki.fi:10138/156630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/156630","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1590049712","https://openalex.org/W1968669906","https://openalex.org/W1968714831","https://openalex.org/W1969970548","https://openalex.org/W1971874142","https://openalex.org/W1975413561","https://openalex.org/W1975459904","https://openalex.org/W1976094322","https://openalex.org/W1976519721","https://openalex.org/W1991144596","https://openalex.org/W1999140958","https://openalex.org/W2002626261","https://openalex.org/W2003369939","https://openalex.org/W2008928751","https://openalex.org/W2012863747","https://openalex.org/W2016016217","https://openalex.org/W2020706581","https://openalex.org/W2021056798","https://openalex.org/W2023292526","https://openalex.org/W2028419900","https://openalex.org/W2038717349","https://openalex.org/W2039522486","https://openalex.org/W2045192768","https://openalex.org/W2047722872","https://openalex.org/W2051434026","https://openalex.org/W2051707492","https://openalex.org/W2054859560","https://openalex.org/W2059103024","https://openalex.org/W2062139349","https://openalex.org/W2073543701","https://openalex.org/W2075880115","https://openalex.org/W2078731312","https://openalex.org/W2091470148","https://openalex.org/W2094521642","https://openalex.org/W2102221735","https://openalex.org/W2123366884","https://openalex.org/W2128874753","https://openalex.org/W2132135347","https://openalex.org/W2132472275","https://openalex.org/W2132589192","https://openalex.org/W2133212152","https://openalex.org/W2159176257","https://openalex.org/W2162928891","https://openalex.org/W2170344041","https://openalex.org/W2299947939","https://openalex.org/W2316058382","https://openalex.org/W2331205033"],"related_works":["https://openalex.org/W2050962336","https://openalex.org/W3084118589","https://openalex.org/W2792487481","https://openalex.org/W195326389","https://openalex.org/W2886381481","https://openalex.org/W2088709381","https://openalex.org/W2089611642","https://openalex.org/W1994341736","https://openalex.org/W4403516251","https://openalex.org/W4255148069"],"abstract_inverted_index":{"The":[0,162,330],"main":[1],"goals":[2],"of":[3,23,42,53,61,100,115,119,134,139,144,167,190,206,216,219,226,261],"neuroanesthesia":[4,43],"are":[5],"to":[6,19,27,38,46,81,87,92,127,149,157,172,275,345],"maintain":[7],"adequate":[8],"cerebral":[9,15],"perfusion":[10],"pressure":[11,231,250,300],"(CPP)":[12],"and,":[13],"consequently,":[14,284],"blood":[16,49,54,63,76,175,268,299],"flow":[17],"(CBF)":[18],"guarantee":[20],"sufficient":[21],"oxygenation":[22],"the":[24,33,59,88,113,129,135,179,203,242,337,357],"brain":[25,194],"and":[26,51,131,211,251,283,291,301],"provide":[28],"good":[29],"surgical":[30],"conditions":[31],"for":[32,70,151,188],"neurosurgeon.":[34],"This":[35],"thesis":[36],"aimed":[37],"examine":[39],"critical":[40],"aspects":[41],"with":[44,97,296,308],"regard":[45],"CBF,":[47],"CPP,":[48],"coagulation,":[50],"transfusion":[52,65,78],"products.":[55],"In":[56,112],"our":[57,255],"material":[58],"requirement":[60,332],"intraoperative":[62,98,117],"product":[64],"was":[66],"low":[67],"during":[68,325],"surgery":[69],"ruptured":[71],"arterial":[72,227,249,267],"aneurysm.":[73,102,136],"Intraoperative":[74,103],"red":[75],"cell":[77],"(RBCT)":[79],"seems":[80],"be":[82,125,147,264],"preemptive":[83,305],"in":[84,155,241,247,254,271,281,285,288,298,327],"nature":[85],"according":[86],"hemoglobin":[89],"levels":[90],"prior":[91],"transfusion.":[93],"RBCT":[94,104],"is":[95,236,294,343,350],"associated":[96,295],"rupture":[99,118],"an":[101,120,185,224],"may":[105,177],"itself":[106],"worsen":[107],"SAH":[108],"patients":[109,272],"neurological":[110],"outcome.":[111],"event":[114],"sudden":[116],"aneurysm,":[121],"adenosine-induced":[122],"asystole":[123],"can":[124],"used":[126],"stop":[128],"bleeding":[130,154,200],"facilitate":[132],"clipping":[133],"Early":[137],"infusion":[138],"fresh":[140],"frozen":[141],"plasma":[142],"instead":[143],"crystalloids":[145],"should":[146,263],"considered":[148],"compensate":[150],"expected":[152],"excess":[153,199],"neurosurgery":[156,274,326],"preserve":[158],"normal":[159],"coagulation":[160,176],"capacity.":[161],"potentially":[163,278],"less":[164,341],"harmful":[165,279],"effect":[166],"hypertonic":[168],"saline":[169],"(HS),":[170],"relative":[171],"mannitol,":[173],"on":[174],"shift":[178],"decision":[180],"towards":[181],"HS":[182],"when":[183,198],"choosing":[184],"optimal":[186],"solution":[187],"treatment":[189],"elevated":[191],"ICP":[192],"or":[193,313],"swelling,":[195],"at":[196],"least":[197],"occurs.":[201],"However,":[202,304],"clinical":[204],"relevance":[205],"this":[207,354],"finding":[208],"remains":[209],"unclear":[210],"warrants":[212],"further":[213],"study.":[214,256],"Reliability":[215],"end-tidal":[217],"concentration":[218],"carbon":[220,228],"dioxide":[221,229],"(EtCO2)":[222],"as":[223,239],"estimate":[225],"partial":[230],"(PaCO2)":[232],"after":[233,259],"anesthesia":[234,262],"induction":[235,260],"not":[237,334],"adequate,":[238],"seen":[240],"correlation":[243],"between":[244,336],"a":[245,277,321],"decrease":[246],"mean":[248],"EtCO2-PaCO2":[252],"difference":[253],"Optimal":[257],"ventilation":[258],"confirmed":[265],"by":[266],"gas":[269],"analysis":[270],"undergoing":[273],"prevent":[276],"increase":[280],"PaCO2,":[282],"CBF.":[286],"Anesthesia":[287],"both":[289,328],"sitting":[290],"prone":[292],"positions":[293],"changes":[297],"cardiac":[302],"function.":[303],"goal-directed":[306],"therapy":[307],"either":[309],"Ringer":[310],"s":[311],"acetate":[312],"hydroxyethyl":[314],"starch":[315],"(HES)":[316],"solutions":[317],"before":[318],"positioning":[319],"enables":[320],"stable":[322],"hemodynamic":[323],"state":[324],"positions.":[329,339],"fluid":[331],"did":[333],"differ":[335],"two":[338],"Slightly":[340],"HES":[342],"needed":[344],"achieve":[346],"comparable":[347],"hemodynamics,":[348],"but":[349],"it":[351],"questionable":[352],"whether":[353],"advantage":[355],"outweighs":[356],"recent":[358],"concerns":[359],"regarding":[360],"colloid":[361],"safety.":[362]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
