{"id":"https://openalex.org/W2236760940","doi":null,"title":"Thiopental alters long term nociceptive response of young rats","display_name":"Thiopental alters long term nociceptive response of young rats","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2236760940","mag":"2236760940"},"language":"en","primary_location":{"id":"pmh:oai:www.lume.ufrgs.br:10183/225965","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/225965","pdf_url":"http://hdl.handle.net/10183/225965","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UFRGS","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10183/225965","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103235931","display_name":"Giovana Dantas","orcid":"https://orcid.org/0000-0001-6530-1603","observed_orcids":["https://orcid.org/0000-0001-6530-1603"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giovana Dantas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062316896","display_name":"Gabriela Laste","orcid":"https://orcid.org/0000-0003-1554-6658","observed_orcids":["https://orcid.org/0000-0003-1554-6658"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriela Laste","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107823822","display_name":"Joanna Ripoll Rozisky","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joanna Ripoll Rozisky","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014448554","display_name":"Iraci Lucena da Silva Torres","orcid":"https://orcid.org/0000-0002-3081-115X","observed_orcids":["https://orcid.org/0000-0002-3081-115X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Iraci L.S. Torres","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5051771270","display_name":"Maria Beatriz Cardoso Ferreira","orcid":"https://orcid.org/0000-0002-6814-6773","observed_orcids":["https://orcid.org/0000-0002-6814-6773","https://orcid.org/0000-0002-4099-3364"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Beatriz  Cardoso Ferreira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2312,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.57392107,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.7505000233650208,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.7505000233650208,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11905","display_name":"Veterinary Pharmacology and Anesthesia","score":0.1356000006198883,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12963","display_name":"Anesthesia and Neurotoxicity Research","score":0.05649999901652336,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thiopental","display_name":"thiopental","score":1.0},{"id":"https://openalex.org/keywords/halothane","display_name":"halothane","score":0.9929999709129333},{"id":"https://openalex.org/keywords/general-anesthesia","display_name":"general anesthesia","score":0.6269999742507935},{"id":"https://openalex.org/keywords/nociception","display_name":"nociception","score":0.8220000267028809},{"id":"https://openalex.org/keywords/hyperalgesia","display_name":"hyperalgesia","score":0.8709999918937683},{"id":"https://openalex.org/keywords/tail-flick-latency","display_name":"tail-flick latency","score":0.878000020980835},{"id":"https://openalex.org/keywords/juvenile-rats","display_name":"young rats","score":0.8130000233650208},{"id":"https://openalex.org/keywords/inhalational-anesthetics","display_name":"inhalational anesthetics","score":0.6769999861717224},{"id":"https://openalex.org/keywords/intravenous-anesthetics","display_name":"intravenous anesthetics","score":0.9810000061988831}],"concepts":[{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.6387327313423157},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.49172475934028625},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.48916247487068176},{"id":"https://openalex.org/C2776932660","wikidata":"https://www.wikidata.org/wiki/Q32921","display_name":"Halothane","level":2,"score":0.48523569107055664},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.45849645137786865},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4491705894470215},{"id":"https://openalex.org/C2910962159","wikidata":"https://www.wikidata.org/wiki/Q410179","display_name":"Thiopental Sodium","level":3,"score":0.4355655312538147},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37435752153396606},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27403974533081055},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07652559876441956},{"id":"https://openalex.org/C2776277131","wikidata":"https://www.wikidata.org/wiki/Q422740","display_name":"Propofol","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:www.lume.ufrgs.br:10183/225965","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/225965","pdf_url":"http://hdl.handle.net/10183/225965","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UFRGS","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:44cdd6ddca6243a5bf51316376ad8a35","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/44cdd6ddca6243a5bf51316376ad8a35","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista de Ci\u00eancias Farmac\u00eauticas B\u00e1sica e Aplicada, Vol 36, Iss 2 (2015)","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:ab37882624624252b4aeefec69304945","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/ab37882624624252b4aeefec69304945","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista de Ci\u00eancias Farmac\u00eauticas B\u00e1sica e Aplicada, Vol 36, Iss 2 (2015)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:www.lume.ufrgs.br:10183/225965","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/225965","pdf_url":"http://hdl.handle.net/10183/225965","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UFRGS","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2236760940.pdf","grobid_xml":"https://content.openalex.org/works/W2236760940.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1858094726","https://openalex.org/W1968071780","https://openalex.org/W1971408129","https://openalex.org/W1972577147","https://openalex.org/W1973518423","https://openalex.org/W1995661630","https://openalex.org/W1999601502","https://openalex.org/W2002120520","https://openalex.org/W2011381188","https://openalex.org/W2013150544","https://openalex.org/W2019208784","https://openalex.org/W2021733070","https://openalex.org/W2023450003","https://openalex.org/W2023906412","https://openalex.org/W2027124131","https://openalex.org/W2028875667","https://openalex.org/W2038665575","https://openalex.org/W2040576664","https://openalex.org/W2040831152","https://openalex.org/W2058346250","https://openalex.org/W2062700118","https://openalex.org/W2065169750","https://openalex.org/W2065368498","https://openalex.org/W2069675624","https://openalex.org/W2071763249","https://openalex.org/W2077998988","https://openalex.org/W2078963381","https://openalex.org/W2086180395","https://openalex.org/W2086880966","https://openalex.org/W2092002730","https://openalex.org/W2113225634","https://openalex.org/W2130203159","https://openalex.org/W2139148797","https://openalex.org/W2140594985","https://openalex.org/W2142047460","https://openalex.org/W2168132586","https://openalex.org/W2169848851","https://openalex.org/W2206043426"],"related_works":["https://openalex.org/W2294672592","https://openalex.org/W2019366746","https://openalex.org/W1983633909","https://openalex.org/W2055635515","https://openalex.org/W1968071780","https://openalex.org/W2077114922","https://openalex.org/W1973110563","https://openalex.org/W2092463312","https://openalex.org/W2051249090","https://openalex.org/W2045735188"],"abstract_inverted_index":{"The":[0,113],"objective":[1],"of":[2,16,35,38,56,80],"this":[3,117],"study":[4,118],"was":[5,74],"to":[6],"evaluate":[7],"the":[8,23,30,33,52,57,84,110,125,132],"long":[9],"term":[10],"nociceptive":[11,126],"response":[12,127,136],"determined":[13],"by":[14],"use":[15],"two":[17,63],"general":[18],"anesthetics,":[19],"one":[20],"intravenous":[21],"and":[22,45,68],"other":[24],"inhalatory,":[25],"in":[26,62,83,116,128,137],"young":[27,129],"animals.":[28,130],"In":[29,51,70,89],"first":[31],"experiment,":[32,54],"animals":[34],"21":[36,184],"days":[37],"age":[39,59],"were":[40,60,93],"divided":[41,61],"into":[42],"control":[43],"(saline)":[44],"thiopental":[46,86,133],"(35":[47,198],"mg/kg,":[48,199],"i.p.)":[49],"groups.":[50],"second":[53],"rats":[55],"same":[58],"groups":[64,77,97],"\u2013":[65,78,169,213],"halothane":[66,121],"(2%)":[67,215],"control.":[69],"experiment":[71,90],"1,":[72,220],"there":[73,92],"difference":[75],"between":[76,96,100],"reduction":[79],"tail-flick":[81],"latency":[82],"group":[85,103],"(P<":[87],"0.05).":[88],"2,":[91,235],"no":[94,229],"differences":[95],"or":[98],"interaction":[99],"time":[101],"versus":[102],"(F(1,19)=0.11":[104],"for":[105,109],"groups,":[106],"P>0.05;":[107],"F(1,19)=0.032":[108],"interaction,":[111],"P>0.05).":[112],"results":[114],"obtained":[115],"showed":[119],"that":[120],"did":[122],"not":[123],"alter":[124],"However,":[131],"induced":[134],"hyperalgesic":[135],"rats.":[138],"Key":[139],"words:":[140],"Rats.":[141],"Sodium":[142],"thiopental.":[143],"Halothane.":[144],"Nociception.":[145],"Tail":[146],"flick":[147],"latency.":[148],"RESUMO":[149],"O":[150],"objetivo":[151],"desse":[152],"estudo":[153,261],"foi":[154],"avaliar":[155],"a":[156,159,254,268],"resposta":[157,269,278],"nociceptiva":[158,270],"longo":[160],"prazo":[161],"relacionada":[162],"ao":[163],"uso":[164],"de":[165,183,186,205,225,289],"dois":[166,211],"anest\u00e9sicos":[167],"gerais":[168],"um":[170],"intravenoso":[171],"e":[172,195,216],"outro":[173],"inalat\u00f3rio,":[174],"em":[175,210,271],"animais":[176,182,204,272],"jovens.":[177,273],"No":[178,201,218,233],"primeiro":[179],"experimento,":[180,203],"os":[181,240],"dias":[185],"idade":[187,207],"foram":[188,208],"divididos":[189,209],"nos":[190],"grupos":[191,212,241],"controle":[192],"(solu\u00e7\u00e3o":[193],"salina)":[194],"tiopental":[196,231,276],"s\u00f3dico":[197],"i.p.).":[200],"segundo":[202],"mesma":[206],"halotano":[214,265],"controle.":[217],"Experimento":[219,234],"houve":[221,237],"redu\u00e7\u00e3o":[222],"da":[223,227,291],"lat\u00eancia":[224],"retirada":[226,290],"cauda":[228],"grupo":[230,245],"(P<0,05).":[232],"n\u00e3o":[236,266],"diferen\u00e7a":[238],"entre":[239,244],"ou":[242],"intera\u00e7\u00e3o":[243],"x":[246],"tempo":[247],"(F(1,19)=0,11":[248],"para":[249,253],"grupos,":[250],"P>0,05;":[251],"F(1,19)=0,032":[252],"intera\u00e7\u00e3o,":[255],"P>0,05).":[256],"Os":[257],"resultados":[258],"obtidos":[259],"nesse":[260],"demonstraram":[262],"que":[263],"o":[264,275],"altera":[267],"Entretanto,":[274],"induziu":[277],"hiperalg\u00e9sica":[279],"nestes":[280],"ratos.":[281],"Palavras-chave:":[282],"Ratos.":[283],"Tiopental":[284],"s\u00f3dico.":[285],"Halotano.":[286],"Nocicep\u00e7\u00e3o.":[287],"Lat\u00eancia":[288],"cauda.":[292]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}