{"id":"https://openalex.org/W2235564299","doi":"https://doi.org/10.34626/n2d0-2t38","title":"A S\u00cdNDROME DA APNEIA OBSTRUTIVA DO SONO E O S\u00cdNDROME METAB\u00d3LICO: ENTIDADES INSEPAR\u00c1VEIS","display_name":"A S\u00cdNDROME DA APNEIA OBSTRUTIVA DO SONO E O S\u00cdNDROME METAB\u00d3LICO: ENTIDADES INSEPAR\u00c1VEIS","publication_year":2012,"publication_date":"2012-07-24","ids":{"openalex":"https://openalex.org/W2235564299","doi":"https://doi.org/10.34626/n2d0-2t38","mag":"2235564299"},"language":"pt","primary_location":{"id":"pmh:oai:repositorio-aberto.up.pt:10216/66115","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10216/66115","pdf_url":"https://repositorio-aberto.up.pt/bitstream/10216/66115/2/30833.pdf","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"master thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://repositorio-aberto.up.pt/bitstream/10216/66115/2/30833.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102011192","display_name":"Gustavo Duarte","orcid":"https://orcid.org/0000-0002-9402-7671","observed_orcids":["https://orcid.org/0000-0002-9402-7671"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Duarte, Gustavo Gaspar Peixoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5102011192"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.8949999809265137},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.9850000143051147},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6079999804496765},{"id":"https://openalex.org/keywords/visceral-adipose-tissue","display_name":"visceral adipose tissue","score":0.9539999961853027},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8289999961853027},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.734000027179718},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.9359999895095825},{"id":"https://openalex.org/keywords/intermittent-hypoxia","display_name":"intermittent hypoxia","score":0.972000002861023},{"id":"https://openalex.org/keywords/sleep-fragmentation","display_name":"sleep fragmentation","score":0.8450000286102295},{"id":"https://openalex.org/keywords/sympathetic-activation","display_name":"sympathetic activation","score":0.9430000185966492},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7960000038146973},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9959999918937683},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/adipocytes","display_name":"adipocytes","score":0.3569999933242798},{"id":"https://openalex.org/keywords/pathophysiological-mechanisms","display_name":"pathophysiological mechanisms","score":0.6299999952316284},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.4480000138282776},{"id":"https://openalex.org/keywords/underdiagnosis","display_name":"underdiagnosis","score":0.6399999856948853},{"id":"https://openalex.org/keywords/cardiovascular-morbidity-and-mortality","display_name":"cardiovascular morbidity and mortality","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42160555720329285},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.34995222091674805},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.3423870801925659},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.32703161239624023},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.11115634441375732}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:repositorio-aberto.up.pt:10216/66115","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10216/66115","pdf_url":"https://repositorio-aberto.up.pt/bitstream/10216/66115/2/30833.pdf","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"master thesis"},{"id":"doi:10.34626/n2d0-2t38","doi":"https://doi.org/10.34626/n2d0-2t38","is_oa":true,"landing_page_url":"https://doi.org/10.34626/n2d0-2t38","pdf_url":null,"source":{"id":"https://openalex.org/S7407051329","display_name":"Universidade do Porto","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},{"id":"mag:2235564299","doi":null,"is_oa":false,"landing_page_url":"https://repositorio-aberto.up.pt/bitstream/10216/66115/2/30833.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repositorio-aberto.up.pt:10216/66115","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10216/66115","pdf_url":"https://repositorio-aberto.up.pt/bitstream/10216/66115/2/30833.pdf","source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"master thesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2235564299.pdf","grobid_xml":"https://content.openalex.org/works/W2235564299.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2593172741","https://openalex.org/W2584209887","https://openalex.org/W6927489426","https://openalex.org/W6946236033","https://openalex.org/W2614661832","https://openalex.org/W6927598887","https://openalex.org/W3180167985","https://openalex.org/W6890091601","https://openalex.org/W2633137001","https://openalex.org/W7005772697"],"abstract_inverted_index":{"Resumo":[0],"O":[1],"S\u00edndrome":[2,29,49,56,69,77,133,150,195,264],"Metab\u00f3lico":[3,151],"\u00e9":[4,35,53,139,258],"uma":[5,36,179,260],"entidade":[6,37],"cl\u00ednica":[7],"constitu\u00edda":[8],"pela":[9],"coocorr\u00eancia":[10],"de":[11,24,26,30,55,130,134,141,259,265],"obesidade,":[12],"resist\u00eancia":[13],"insul\u00ednica,":[14],"hipertens\u00e3o":[15],"e":[16,18,43,75,88,112,152,160,184,209,252],"dislipid\u00e9mia,":[17],"est\u00e1":[19,44],"associada":[20],"a":[21,64,68,79,89,132,158,170,189,234,241,255,282],"um":[22],"aumento":[23,84,226],"morbo-mortalidade":[25],"origem":[27],"cardiovascular.A":[28],"Apneia":[31,71,135,266],"Obstrutiva":[32,72,136],"do":[33,73,85,137,149,162,172,194,227,267,275,277],"Sono":[34,74,138,268],"sub-diagnosticada,":[38],"cada":[39],"vez":[40],"mais":[41,249,285],"prevalente":[42],"intimamente":[45],"relacionada":[46],"com":[47,92,200],"o":[48,76,83,93,145,201,284],"Metab\u00f3lico.A":[50,196],"sua":[51,80],"associa\u00e7\u00e3o":[52,97],"denominada":[54],"Z.":[57],"Os":[58],"objetivos":[59],"deste":[60],"trabalho":[61],"s\u00e3o":[62,176,247],"rever":[63],"rela\u00e7\u00e3o":[65,90,197,217,242],"existente":[66],"entre":[67,218,244],"da":[70,118,121,263],"Metab\u00f3lico,":[78],"contribui\u00e7\u00e3o":[81],"para":[82,144,239],"risco":[86,142,228],"cardiovascular":[87],"destas":[91,198,236],"tecido":[94,278],"adiposo":[95],"visceral.Esta":[96],"n\u00e3o":[98],"existe":[99,128],"s\u00f3":[100],"pelo":[101],"elemento":[102],"comum":[103],"-obesidademas":[104],"tamb\u00e9m":[105],"devida":[106],"\u00e0":[107,231],"semelhan\u00e7a":[108],"dos":[109,147,165],"mecanismos":[110],"fisiopatol\u00f3gicos":[111],"disfun\u00e7\u00f5es":[113],"metab\u00f3licas":[114,191],"que":[115,131,187,223,233,238],"ambas":[116],"desencadeiam.Apesar":[117],"maior":[119,261],"incid\u00eancia":[120],"obesidade/gordura":[122],"visceral":[123,203,280],"nas":[124],"altera\u00e7\u00f5es":[125,190,272],"metab\u00f3licas,":[126,273],"j\u00e1":[127],"evid\u00eancia":[129,256],"fator":[140],"independente":[143],"desenvolvimento":[146,270],"componentes":[148],"outras":[153],"doen\u00e7as":[154],"cardiovasculares.A":[155],"hipoxia":[156],"intermitente,":[157],"priva\u00e7\u00e3o":[159],"fragmenta\u00e7\u00e3o":[161],"sono":[163],"derivadas":[164],"epis\u00f3dios":[166],"apneicos,":[167],"bem":[168],"como":[169],"ativa\u00e7\u00e3o":[171],"Sistema":[173],"Nervoso":[174],"Simp\u00e1tico":[175],"respons\u00e1veis":[177],"por":[178],"inflama\u00e7\u00e3o":[180],"sustentada,":[181],"disfun\u00e7\u00e3o":[182],"endotelial":[183],"stress":[185],"oxidativo":[186],"levar\u00e3o":[188],"similares":[192],"\u00e0s":[193],"entidades":[199],"adip\u00f3cito":[202],"merece":[204],"especial":[205],"destaque":[206],"na":[207,216],"evolu\u00e7\u00e3o":[208],"progress\u00e3o":[210],"das":[211,271],"consequ\u00eancias":[212],"metab\u00f3licas.Parece":[213],"haver":[214],"sinergismos":[215],"estas":[219,245],"duas":[220],"entidades,":[221],"no":[222,269,287],"toca":[224],"ao":[225],"cardiovascular,":[229],"principalmente":[230],"medida":[232],"gravidade":[235],"aumenta.Concluiu-se":[237],"estudar":[240],"causal":[243],"s\u00edndromes":[246],"necess\u00e1rios":[248],"estudos":[250],"longitudinais":[251],"controlados.No":[253],"entanto,":[254],"crescente":[257],"implica\u00e7\u00e3o":[262],"apesar":[274],"papel":[276],"gordo":[279],"continuar":[281],"ser":[283],"determinante":[286],"seu":[288],"desenvolvimento.":[289]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}