{"id":"https://openalex.org/W2234756268","doi":null,"title":"Construction of a Novel Recombinant Escherichia coli Strain Capable of Simultaneously Utilizing Glucose and Xylose","display_name":"Construction of a Novel Recombinant Escherichia coli Strain Capable of Simultaneously Utilizing Glucose and Xylose","publication_year":2013,"publication_date":"2013-11-01","ids":{"openalex":"https://openalex.org/W2234756268","mag":"2234756268"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.unist.ac.kr:201301/1057","doi":null,"is_oa":true,"landing_page_url":"http://unist.dcollection.net/jsp/common/DcLoOrgPer.jsp?sItemId=000001655988","pdf_url":"https://scholarworks.unist.ac.kr/handle/201301/1057","source":{"id":"https://openalex.org/S4306401118","display_name":"Scholarworks@UNIST (Ulsan National Institute of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I48566637","host_organization_name":"Ulsan National Institute of Science and Technology","host_organization_lineage":["https://openalex.org/I48566637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Master's thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarworks.unist.ac.kr/handle/201301/1057","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113483110","display_name":"Seong Hun Jeong","orcid":"https://orcid.org/0009-0001-5877-7678","observed_orcids":["https://orcid.org/0009-0001-5877-7678"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Seong Hun Jeong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5113483110"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glucose-xylose-co-fermentation","display_name":"glucose-xylose co-fermentation","score":0.8889999985694885},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8209999799728394},{"id":"https://openalex.org/keywords/carbon-catabolite-repression","display_name":"catabolite repression","score":0.9079999923706055},{"id":"https://openalex.org/keywords/xylose-metabolism","display_name":"xylose metabolism","score":0.8539999723434448},{"id":"https://openalex.org/keywords/constitutive-promoters","display_name":"constitutive promoters","score":0.9449999928474426},{"id":"https://openalex.org/keywords/adaptive-evolution","display_name":"adaptive evolution","score":0.9330000281333923},{"id":"https://openalex.org/keywords/synthetic-promoters","display_name":"synthetic promoters","score":0.8370000123977661},{"id":"https://openalex.org/keywords/lignocellulosic-biomass","display_name":"lignocellulosic biomass","score":0.8730000257492065},{"id":"https://openalex.org/keywords/genome-editing","display_name":"genome editing","score":0.5569999814033508},{"id":"https://openalex.org/keywords/bioproducts","display_name":"bioproducts","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.7594999074935913},{"id":"https://openalex.org/C2780294150","wikidata":"https://www.wikidata.org/wiki/Q66589603","display_name":"Xylose","level":3,"score":0.7122519016265869},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.6694222092628479},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.6618304252624512},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4247328042984009},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4005904197692871},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3287747800350189},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2711099684238434},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2487465739250183},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.20986822247505188},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09958189725875854},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0633760392665863}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:scholarworks.unist.ac.kr:201301/1057","doi":null,"is_oa":true,"landing_page_url":"http://unist.dcollection.net/jsp/common/DcLoOrgPer.jsp?sItemId=000001655988","pdf_url":"https://scholarworks.unist.ac.kr/handle/201301/1057","source":{"id":"https://openalex.org/S4306401118","display_name":"Scholarworks@UNIST (Ulsan National Institute of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I48566637","host_organization_name":"Ulsan National Institute of Science and Technology","host_organization_lineage":["https://openalex.org/I48566637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Master's thesis"},{"id":"mag:2234756268","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.unist.ac.kr/bitstream/201301/1057/1/Construction%20of%20a%20Novel%20Recombinant%20Escherichia%20coli%20Strain.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarworks.unist.ac.kr:201301/1057","doi":null,"is_oa":true,"landing_page_url":"http://unist.dcollection.net/jsp/common/DcLoOrgPer.jsp?sItemId=000001655988","pdf_url":"https://scholarworks.unist.ac.kr/handle/201301/1057","source":{"id":"https://openalex.org/S4306401118","display_name":"Scholarworks@UNIST (Ulsan National Institute of Science and Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I48566637","host_organization_name":"Ulsan National Institute of Science and Technology","host_organization_lineage":["https://openalex.org/I48566637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Master's thesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2234756268.pdf","grobid_xml":"https://content.openalex.org/works/W2234756268.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W1525972719","https://openalex.org/W1532383968","https://openalex.org/W1607918644","https://openalex.org/W1771671623","https://openalex.org/W1903320665","https://openalex.org/W1968509014","https://openalex.org/W1972403536","https://openalex.org/W1972875046","https://openalex.org/W1974879552","https://openalex.org/W1981560730","https://openalex.org/W1989015881","https://openalex.org/W1990722231","https://openalex.org/W1999433900","https://openalex.org/W2000244693","https://openalex.org/W2001721950","https://openalex.org/W2006203409","https://openalex.org/W2007389618","https://openalex.org/W2009392979","https://openalex.org/W2014361215","https://openalex.org/W2021313883","https://openalex.org/W2030794862","https://openalex.org/W2031146914","https://openalex.org/W2036449301","https://openalex.org/W2038683612","https://openalex.org/W2042847327","https://openalex.org/W2044338870","https://openalex.org/W2055658855","https://openalex.org/W2057601066","https://openalex.org/W2058686369","https://openalex.org/W2059680577","https://openalex.org/W2063855430","https://openalex.org/W2069568056","https://openalex.org/W2071075154","https://openalex.org/W2083119773","https://openalex.org/W2085075090","https://openalex.org/W2089933528","https://openalex.org/W2090072316","https://openalex.org/W2090806625","https://openalex.org/W2093548226","https://openalex.org/W2094216282","https://openalex.org/W2095197013","https://openalex.org/W2095407700","https://openalex.org/W2098839738","https://openalex.org/W2101197109","https://openalex.org/W2105250945","https://openalex.org/W2105636171","https://openalex.org/W2109910682","https://openalex.org/W2116137883","https://openalex.org/W2126856019","https://openalex.org/W2129887334","https://openalex.org/W2134153749","https://openalex.org/W2138596848","https://openalex.org/W2142982903","https://openalex.org/W2144779133","https://openalex.org/W2148899088","https://openalex.org/W2151463520","https://openalex.org/W2152007804","https://openalex.org/W2152808252","https://openalex.org/W2156439743","https://openalex.org/W2162395942","https://openalex.org/W2165864045","https://openalex.org/W2166837862","https://openalex.org/W2312224748","https://openalex.org/W2419079520"],"related_works":["https://openalex.org/W632958011","https://openalex.org/W4281392607","https://openalex.org/W7168280843","https://openalex.org/W2959218880","https://openalex.org/W2312224748","https://openalex.org/W2952470240","https://openalex.org/W2117280310","https://openalex.org/W2258606127","https://openalex.org/W7220830645","https://openalex.org/W4410098603"],"abstract_inverted_index":{"Lignocellulose-derived":[0],"carbon":[1,33],"sources":[2],"are":[3],"attractive":[4],"to":[5,49,75,86,143],"produce":[6],"valuable":[7,22,150],"biofuels":[8],"and":[9,45,53,160],"biochemicals.":[10],"Despite":[11],"many":[12],"approaches":[13],"have":[14,58],"been":[15],"intensively":[16],"attempted":[17],"for":[18,129,149],"the":[19,60,88,93,102,124],"production":[20],"of":[21,97,101,126,158],"bioproducts":[23,151],"in":[24,73,78,113,118],"Escherichia":[25],"coli,":[26],"there":[27],"still":[28],"problems":[29],"remaining":[30],"such":[31],"as":[32],"catabolite":[34],"repression":[35],"(CCR).":[36],"Since":[37],"non-engineered":[38],"E.":[39,79,104],"coli":[40,105],"cannot":[41],"simultaneously":[42],"utilize":[43],"glucose":[44,159],"xylose,":[46],"it":[47],"leads":[48],"longer":[50],"fermentation":[51],"times":[52],"lower":[54],"productivities.":[55],"Recently,":[56],"we":[57,82,122],"found":[59,112],"enhanced":[61],"glucose-xylose":[62],"co-fermenting":[63],"strains":[64,106],"by":[65,92,132],"using":[66,133],"xylose":[67,89,130],"metabolic":[68,119],"operon":[69],"with":[70],"constitutive":[71],"promoters,":[72],"order":[74],"exclude":[76],"CCR":[77],"coli.":[80],"Further,":[81],"performed":[83],"adaptive":[84],"evolution":[85],"strengthen":[87],"metabolism":[90,131],"mediated":[91],"synthetic":[94],"promoters.":[95],"Analysis":[96],"whole":[98],"genome":[99,135],"re-sequencing":[100],"adapted":[103,115],"showed":[107],"that":[108],"four":[109],"mutations":[110,128],"were":[111],"each":[114],"strain":[116,148],"resulting":[117],"changes.":[120],"Consequently":[121],"confirmed":[123],"significance":[125],"these":[127],"precise":[134],"engineering":[136],"tools.":[137],"This":[138],"study":[139],"would":[140],"be":[141],"helpful":[142],"design":[144],"an":[145],"efficient":[146],"platform":[147],"from":[152],"lignocellulosic":[153],"biomass":[154],"containing":[155],"large":[156],"amount":[157],"xylose.":[161]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2016-06-24T00:00:00"}