{"id":"https://openalex.org/W2232519919","doi":"https://doi.org/10.1007/978-1-4939-1191-2_4","title":"Cyclosporines: Biosynthesis and Beyond","display_name":"Cyclosporines: Biosynthesis and Beyond","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2232519919","doi":"https://doi.org/10.1007/978-1-4939-1191-2_4","mag":"2232519919"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4939-1191-2_4","doi":"https://doi.org/10.1007/978-1-4939-1191-2_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4939-1191-2_4","pdf_url":null,"source":{"id":"https://openalex.org/S4210230153","display_name":"Fungal biology","issn_l":"2198-7777","issn":["2198-7777","2198-7785"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fungal Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1250236606","display_name":"Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020748618","display_name":"Tony Velkov","orcid":"https://orcid.org/0000-0002-0017-7952","observed_orcids":["https://orcid.org/0000-0002-0017-7952"]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Tony Velkov","raw_affiliation_strings":["Department of Pharmaceutics, Monash University, Parkville, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Monash University, Parkville, VIC, Australia","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074972614","display_name":"Alfons Lawen","orcid":"https://orcid.org/0000-0001-6553-9945","observed_orcids":["https://orcid.org/0000-0001-6553-9945"]},"institutions":[{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Alfons Lawen","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Melbourne, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Melbourne, VIC, Australia","institution_ids":["https://openalex.org/I56590836"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5074972614"],"corresponding_institution_ids":["https://openalex.org/I56590836"],"apc_list":null,"apc_paid":null,"fwci":1.8736,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.8659595,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"65","last_page":"88"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclosporine","display_name":"cyclosporine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/nonribosomal-peptide-synthetase","display_name":"nonribosomal peptide synthetase","score":0.9769999980926514},{"id":"https://openalex.org/keywords/tolypocladium-inflatum","display_name":"Tolypocladium inflatum","score":0.9779999852180481},{"id":"https://openalex.org/keywords/fungal-secondary-metabolism","display_name":"fungal secondary metabolism","score":0.7749999761581421},{"id":"https://openalex.org/keywords/n-methylation","display_name":"N-methylation","score":0.8140000104904175},{"id":"https://openalex.org/keywords/immunosuppressive-drugs","display_name":"immunosuppressants","score":0.6980000138282776},{"id":"https://openalex.org/keywords/organ-transplantation","display_name":"organ transplantation","score":0.5249999761581421},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.3919999897480011}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7775218486785889},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.6995375156402588},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5593386888504028},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.5518820285797119},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.49712732434272766},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4500744640827179},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.42395544052124023},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.4144018888473511},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10169008374214172},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.09577816724777222},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0946333110332489}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4939-1191-2_4","doi":"https://doi.org/10.1007/978-1-4939-1191-2_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4939-1191-2_4","pdf_url":null,"source":{"id":"https://openalex.org/S4210230153","display_name":"Fungal biology","issn_l":"2198-7777","issn":["2198-7777","2198-7785"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Fungal Biology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4043000042438507}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":144,"referenced_works":["https://openalex.org/W45088497","https://openalex.org/W641824313","https://openalex.org/W1013130271","https://openalex.org/W1491358981","https://openalex.org/W1495878229","https://openalex.org/W1517954442","https://openalex.org/W1546849601","https://openalex.org/W1566716279","https://openalex.org/W1584186345","https://openalex.org/W1587696955","https://openalex.org/W1593612801","https://openalex.org/W1596255677","https://openalex.org/W1602746521","https://openalex.org/W1608216620","https://openalex.org/W1661847997","https://openalex.org/W1670081794","https://openalex.org/W1924133121","https://openalex.org/W1941924385","https://openalex.org/W1965585392","https://openalex.org/W1970520750","https://openalex.org/W1973035470","https://openalex.org/W1973059973","https://openalex.org/W1973223043","https://openalex.org/W1974172219","https://openalex.org/W1975216099","https://openalex.org/W1977704501","https://openalex.org/W1978148517","https://openalex.org/W1979488831","https://openalex.org/W1982070824","https://openalex.org/W1982958200","https://openalex.org/W1983061734","https://openalex.org/W1984083401","https://openalex.org/W1984851737","https://openalex.org/W1986645514","https://openalex.org/W1987062044","https://openalex.org/W1990783608","https://openalex.org/W1990812439","https://openalex.org/W1991795245","https://openalex.org/W1992744133","https://openalex.org/W2000134506","https://openalex.org/W2000176823","https://openalex.org/W2001946192","https://openalex.org/W2002631857","https://openalex.org/W2003706451","https://openalex.org/W2003765981","https://openalex.org/W2004542850","https://openalex.org/W2007343995","https://openalex.org/W2008114749","https://openalex.org/W2008733674","https://openalex.org/W2009456978","https://openalex.org/W2012394508","https://openalex.org/W2012474757","https://openalex.org/W2013116132","https://openalex.org/W2013612636","https://openalex.org/W2013966777","https://openalex.org/W2016046073","https://openalex.org/W2018849951","https://openalex.org/W2018936231","https://openalex.org/W2022103755","https://openalex.org/W2023888521","https://openalex.org/W2024666387","https://openalex.org/W2025603734","https://openalex.org/W2025733284","https://openalex.org/W2028223358","https://openalex.org/W2029805256","https://openalex.org/W2030896354","https://openalex.org/W2032737956","https://openalex.org/W2033047693","https://openalex.org/W2033877033","https://openalex.org/W2037649969","https://openalex.org/W2043650544","https://openalex.org/W2043677695","https://openalex.org/W2044236886","https://openalex.org/W2046069017","https://openalex.org/W2046213778","https://openalex.org/W2046830658","https://openalex.org/W2047261739","https://openalex.org/W2047695364","https://openalex.org/W2049083467","https://openalex.org/W2049178799","https://openalex.org/W2053175174","https://openalex.org/W2053213384","https://openalex.org/W2053516177","https://openalex.org/W2057819846","https://openalex.org/W2058926555","https://openalex.org/W2059117179","https://openalex.org/W2059504647","https://openalex.org/W2063212143","https://openalex.org/W2063835653","https://openalex.org/W2064465533","https://openalex.org/W2065705005","https://openalex.org/W2066483109","https://openalex.org/W2075561057","https://openalex.org/W2077047167","https://openalex.org/W2078248506","https://openalex.org/W2078267612","https://openalex.org/W2082587144","https://openalex.org/W2082813397","https://openalex.org/W2086470568","https://openalex.org/W2089475202","https://openalex.org/W2090219189","https://openalex.org/W2092022278","https://openalex.org/W2099117662","https://openalex.org/W2100380533","https://openalex.org/W2101600846","https://openalex.org/W2103254492","https://openalex.org/W2103287691","https://openalex.org/W2103368826","https://openalex.org/W2103586220","https://openalex.org/W2110323022","https://openalex.org/W2114064167","https://openalex.org/W2118484018","https://openalex.org/W2118502418","https://openalex.org/W2120650350","https://openalex.org/W2123621483","https://openalex.org/W2125778807","https://openalex.org/W2133423088","https://openalex.org/W2136391678","https://openalex.org/W2137849882","https://openalex.org/W2146585480","https://openalex.org/W2147443793","https://openalex.org/W2149227294","https://openalex.org/W2151719116","https://openalex.org/W2161246113","https://openalex.org/W2163996875","https://openalex.org/W2167397435","https://openalex.org/W2188185325","https://openalex.org/W2212662171","https://openalex.org/W2238023010","https://openalex.org/W2315377404","https://openalex.org/W2330088745","https://openalex.org/W2330341694","https://openalex.org/W2401910362","https://openalex.org/W2402568427","https://openalex.org/W2410429922","https://openalex.org/W2412305100","https://openalex.org/W2438433946","https://openalex.org/W2477057870","https://openalex.org/W2494353375","https://openalex.org/W4211040508","https://openalex.org/W4237200343","https://openalex.org/W4248488798","https://openalex.org/W4254711499","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2016046073","https://openalex.org/W2439339734","https://openalex.org/W2895586625","https://openalex.org/W2030896354","https://openalex.org/W1602746521","https://openalex.org/W7095815613","https://openalex.org/W2053175174","https://openalex.org/W2330341694","https://openalex.org/W1608216620","https://openalex.org/W1546849601"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}
