{"id":"https://openalex.org/W2228656337","doi":"https://doi.org/10.1016/j.biopha.2015.12.023","title":"Preparation and pharmaceutical evaluation of acetaminophen nano-fiber tablets: Application of a solvent-based electrospinning method for tableting","display_name":"Preparation and pharmaceutical evaluation of acetaminophen nano-fiber tablets: Application of a solvent-based electrospinning method for tableting","publication_year":2016,"publication_date":"2016-01-08","ids":{"openalex":"https://openalex.org/W2228656337","doi":"https://doi.org/10.1016/j.biopha.2015.12.023","mag":"2228656337","pmid":"https://pubmed.ncbi.nlm.nih.gov/26898420"},"language":"en","primary_location":{"id":"doi:10.1016/j.biopha.2015.12.023","doi":"https://doi.org/10.1016/j.biopha.2015.12.023","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biopha.2015.12.023","pdf_url":null,"source":{"id":"https://openalex.org/S15111687","display_name":"Biomedicine & Pharmacotherapy","issn_l":"0753-3322","issn":["0753-3322","1950-6007"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-2","ki-jl-1","medline","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicine & Pharmacotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076772195","display_name":"Mami Hamori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mami Hamori","raw_affiliation_strings":["Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064690039","display_name":"Kana Nagano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kana Nagano","raw_affiliation_strings":["Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072271766","display_name":"Sayaka Kakimoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sayaka Kakimoto","raw_affiliation_strings":["Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007108013","display_name":"Kazumasa Naruhashi","orcid":"https://orcid.org/0000-0002-1231-5179","observed_orcids":["https://orcid.org/0000-0002-1231-5179"]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazumasa Naruhashi","raw_affiliation_strings":["Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008759538","display_name":"Akiko Kiriyama","orcid":"https://orcid.org/0000-0001-7772-9367","observed_orcids":["https://orcid.org/0000-0001-7772-9367"]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akiko Kiriyama","raw_affiliation_strings":["Department of Pharmacokinetics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacokinetics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032422017","display_name":"Asako Nishimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Asako Nishimura","raw_affiliation_strings":["Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111743912","display_name":"Nobuhito Shibata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72023434","display_name":"Doshisha Women's College of Liberal Arts","ror":"https://ror.org/02p6jga18","country_code":"JP","type":"education","lineage":["https://openalex.org/I72023434"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Nobuhito Shibata","raw_affiliation_strings":["Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan. Electronic address: nshibata@dwc.doshisha.ac.jp","Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan. Electronic address: nshibata@dwc.doshisha.ac.jp","institution_ids":["https://openalex.org/I72023434"]},{"raw_affiliation_string":"Department of Biopharmaceutics, Faculty of Pharmaceutical Science, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto 610-0395, Japan","institution_ids":["https://openalex.org/I72023434"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111743912"],"corresponding_institution_ids":["https://openalex.org/I72023434"],"apc_list":{"value":3610,"currency":"USD","value_usd":3610},"apc_paid":null,"fwci":1.6266,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.78256172,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"78","issue":null,"first_page":"14","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9570000171661377,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.021900000050663948,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.01679999940097332,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paracetamol","display_name":"paracetamol","score":1.0},{"id":"https://openalex.org/keywords/methacrylic-acid-copolymer","display_name":"methacrylic acid copolymer","score":0.8849999904632568},{"id":"https://openalex.org/keywords/eudragit-s100","display_name":"Eudragit S100","score":0.9440000057220459},{"id":"https://openalex.org/keywords/controlled-drug-delivery","display_name":"controlled drug delivery","score":0.7229999899864197},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.7680000066757202},{"id":"https://openalex.org/keywords/ph-dependent-drug-release","display_name":"pH-dependent drug release","score":0.796999990940094},{"id":"https://openalex.org/keywords/tablet-disintegration","display_name":"tablet disintegration","score":0.6460000276565552},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.6549999713897705},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.8019999861717224}],"concepts":[{"id":"https://openalex.org/C144796933","wikidata":"https://www.wikidata.org/wiki/Q1533542","display_name":"Electrospinning","level":3,"score":0.6777931451797485},{"id":"https://openalex.org/C2779849058","wikidata":"https://www.wikidata.org/wiki/Q7673462","display_name":"Tableting","level":2,"score":0.6330669522285461},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6216081976890564},{"id":"https://openalex.org/C2780357685","wikidata":"https://www.wikidata.org/wiki/Q154357","display_name":"Nano-","level":2,"score":0.5330746173858643},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5329801440238953},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.512782633304596},{"id":"https://openalex.org/C519885992","wikidata":"https://www.wikidata.org/wiki/Q161","display_name":"Fiber","level":2,"score":0.5107340812683105},{"id":"https://openalex.org/C91129048","wikidata":"https://www.wikidata.org/wiki/Q594196","display_name":"Nanofiber","level":2,"score":0.4874151051044464},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.46715372800827026},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.4578913152217865},{"id":"https://openalex.org/C163588942","wikidata":"https://www.wikidata.org/wiki/Q5165929","display_name":"Controlled release","level":2,"score":0.45570406317710876},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.43373480439186096},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.35550346970558167},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2751082479953766},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.2192927896976471},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1695581078529358},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.15780681371688843},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.09465745091438293},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000082","descriptor_name":"Acetaminophen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000082","descriptor_name":"Acetaminophen","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D000082","descriptor_name":"Acetaminophen","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004333","descriptor_name":"Drug Administration Routes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008689","descriptor_name":"Methacrylates","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011312","descriptor_name":"Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013607","descriptor_name":"Tablets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014965","descriptor_name":"X-Rays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016018","descriptor_name":"Least-Squares Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057139","descriptor_name":"Nanofibers","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D057139","descriptor_name":"Nanofibers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biopha.2015.12.023","doi":"https://doi.org/10.1016/j.biopha.2015.12.023","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biopha.2015.12.023","pdf_url":null,"source":{"id":"https://openalex.org/S15111687","display_name":"Biomedicine & Pharmacotherapy","issn_l":"0753-3322","issn":["0753-3322","1950-6007"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-2","ki-jl-1","medline","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicine & Pharmacotherapy","raw_type":"journal-article"},{"id":"pmid:26898420","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26898420","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W837690959","https://openalex.org/W1830311524","https://openalex.org/W1967745423","https://openalex.org/W1975715871","https://openalex.org/W1981266770","https://openalex.org/W1983010120","https://openalex.org/W1988345739","https://openalex.org/W1989180570","https://openalex.org/W1991730891","https://openalex.org/W1995317848","https://openalex.org/W1996025190","https://openalex.org/W1997878563","https://openalex.org/W2006228823","https://openalex.org/W2007107040","https://openalex.org/W2008243786","https://openalex.org/W2008805549","https://openalex.org/W2010192296","https://openalex.org/W2027509252","https://openalex.org/W2028424288","https://openalex.org/W2044396597","https://openalex.org/W2055475096","https://openalex.org/W2056008845","https://openalex.org/W2057071345","https://openalex.org/W2057899781","https://openalex.org/W2062572684","https://openalex.org/W2063306981","https://openalex.org/W2066455282","https://openalex.org/W2077815743","https://openalex.org/W2079140183","https://openalex.org/W2088893202","https://openalex.org/W2106727463","https://openalex.org/W2116102494","https://openalex.org/W2137721915","https://openalex.org/W2166832805","https://openalex.org/W2330190529"],"related_works":["https://openalex.org/W2079140183","https://openalex.org/W2166832805","https://openalex.org/W4281490587","https://openalex.org/W2086051986","https://openalex.org/W3209698269","https://openalex.org/W2912115336","https://openalex.org/W2583497251","https://openalex.org/W2563790050","https://openalex.org/W2557720332","https://openalex.org/W2152745786"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}