{"id":"https://openalex.org/W2226775845","doi":"https://doi.org/10.1016/j.chest.2015.12.016","title":"Crises in Sickle Cell Disease","display_name":"Crises in Sickle Cell Disease","publication_year":2015,"publication_date":"2015-12-28","ids":{"openalex":"https://openalex.org/W2226775845","doi":"https://doi.org/10.1016/j.chest.2015.12.016","mag":"2226775845","pmid":"https://pubmed.ncbi.nlm.nih.gov/26836899","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6637264"},"language":"en","primary_location":{"id":"doi:10.1016/j.chest.2015.12.016","doi":"https://doi.org/10.1016/j.chest.2015.12.016","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chest.2015.12.016","pdf_url":"http://journal.chestnet.org/article/S0012369215003451/pdf","source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://journal.chestnet.org/article/S0012369215003451/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020250954","display_name":"Enrico Maria Novelli","orcid":"https://orcid.org/0000-0003-3010-8285","observed_orcids":["https://orcid.org/0000-0003-3010-8285"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Enrico M. Novelli","raw_affiliation_strings":["Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA","Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA","Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007944034","display_name":"Mark T. Gladwin","orcid":"https://orcid.org/0000-0001-7267-9006","observed_orcids":["https://orcid.org/0000-0001-7267-9006"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark T. Gladwin","raw_affiliation_strings":["Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: gladwinmt@upmc.edu","Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA","Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA","Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: gladwinmt@upmc.edu","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5007944034"],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":{"value":4160,"currency":"USD","value_usd":4160},"apc_paid":null,"fwci":1.3632,"has_fulltext":true,"cited_by_count":166,"citation_normalized_percentile":{"value":0.78827038,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"149","issue":"4","first_page":"1082","last_page":"1093"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/vaso-occlusive-crisis","display_name":"vaso-occlusive crisis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acute-chest-syndrome","display_name":"acute chest syndrome","score":0.9900000095367432},{"id":"https://openalex.org/keywords/end-organ-ischemia","display_name":"end-organ ischemia","score":0.9179999828338623},{"id":"https://openalex.org/keywords/hemolysis","display_name":"hemolysis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/red-blood-cell-sickling","display_name":"red blood cell sickling","score":0.7940000295639038},{"id":"https://openalex.org/keywords/blood-transfusion","display_name":"blood transfusion","score":0.8429999947547913},{"id":"https://openalex.org/keywords/red-cell-alloimmunization","display_name":"red blood cell alloimmunization","score":0.7319999933242798},{"id":"https://openalex.org/keywords/immune-dysregulation","display_name":"immune dysregulation","score":0.7260000109672546},{"id":"https://openalex.org/keywords/critical-care-management","display_name":"intensive care management","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9528710246086121},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5360221266746521},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5265422463417053},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2817758321762085}],"mesh":[{"descriptor_ui":"D000741","descriptor_name":"Anemia, Aplastic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D000741","descriptor_name":"Anemia, Aplastic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000741","descriptor_name":"Anemia, Aplastic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001788","descriptor_name":"Blood Grouping and Crossmatching","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005078","descriptor_name":"Exchange Transfusion, Whole Blood","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009102","descriptor_name":"Multiple Organ Failure","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009102","descriptor_name":"Multiple Organ Failure","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009102","descriptor_name":"Multiple Organ Failure","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011697","descriptor_name":"Purpura, Thrombotic Thrombocytopenic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011697","descriptor_name":"Purpura, Thrombotic Thrombocytopenic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011697","descriptor_name":"Purpura, Thrombotic Thrombocytopenic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D017707","descriptor_name":"Erythrocyte Transfusion","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020521","descriptor_name":"Stroke","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D054038","descriptor_name":"Posterior Leukoencephalopathy Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056586","descriptor_name":"Acute Chest Syndrome","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D056586","descriptor_name":"Acute Chest Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D056586","descriptor_name":"Acute Chest Syndrome","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D059408","descriptor_name":"Pain Management","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.chest.2015.12.016","doi":"https://doi.org/10.1016/j.chest.2015.12.016","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chest.2015.12.016","pdf_url":"http://journal.chestnet.org/article/S0012369215003451/pdf","source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6637264","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6637264","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"Text"},{"id":"pmid:26836899","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26836899","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.chest.2015.12.016","doi":"https://doi.org/10.1016/j.chest.2015.12.016","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.chest.2015.12.016","pdf_url":"http://journal.chestnet.org/article/S0012369215003451/pdf","source":{"id":"https://openalex.org/S76900504","display_name":"CHEST Journal","issn_l":"0012-3692","issn":["0012-3692","1931-3543"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chest","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3197132307","display_name":"Platelet TSP1 Mediates Vascular Disease and pulmonary hypertension in Sickle Cell","funder_award_id":"K23HL112848","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2226775845.pdf","grobid_xml":"https://content.openalex.org/works/W2226775845.grobid-xml"},"referenced_works_count":126,"referenced_works":["https://openalex.org/W7956554","https://openalex.org/W50870326","https://openalex.org/W145680385","https://openalex.org/W194436889","https://openalex.org/W194543173","https://openalex.org/W1272191569","https://openalex.org/W1528211603","https://openalex.org/W1545159647","https://openalex.org/W1559736154","https://openalex.org/W1597151660","https://openalex.org/W1820952050","https://openalex.org/W1965318182","https://openalex.org/W1965971764","https://openalex.org/W1968642156","https://openalex.org/W1969949369","https://openalex.org/W1975561845","https://openalex.org/W1976293536","https://openalex.org/W1977841527","https://openalex.org/W1977902516","https://openalex.org/W1978011659","https://openalex.org/W1978298987","https://openalex.org/W1980127925","https://openalex.org/W1980961981","https://openalex.org/W1982483077","https://openalex.org/W1986165815","https://openalex.org/W1986327647","https://openalex.org/W1987382405","https://openalex.org/W1987738542","https://openalex.org/W1987745683","https://openalex.org/W1990033742","https://openalex.org/W1991171158","https://openalex.org/W1992323755","https://openalex.org/W1993119016","https://openalex.org/W1995698717","https://openalex.org/W1997122596","https://openalex.org/W1997547983","https://openalex.org/W1997739956","https://openalex.org/W2000056470","https://openalex.org/W2004524066","https://openalex.org/W2005990638","https://openalex.org/W2013752873","https://openalex.org/W2016226738","https://openalex.org/W2018965817","https://openalex.org/W2024188336","https://openalex.org/W2024351946","https://openalex.org/W2024939795","https://openalex.org/W2026254409","https://openalex.org/W2028505162","https://openalex.org/W2030851049","https://openalex.org/W2031998621","https://openalex.org/W2032993103","https://openalex.org/W2033357297","https://openalex.org/W2034213315","https://openalex.org/W2035268617","https://openalex.org/W2035582196","https://openalex.org/W2036210568","https://openalex.org/W2037174504","https://openalex.org/W2039327271","https://openalex.org/W2042544679","https://openalex.org/W2047264930","https://openalex.org/W2054785459","https://openalex.org/W2058021592","https://openalex.org/W2060753739","https://openalex.org/W2060969789","https://openalex.org/W2067738744","https://openalex.org/W2069755913","https://openalex.org/W2073869392","https://openalex.org/W2077228402","https://openalex.org/W2077716817","https://openalex.org/W2080435312","https://openalex.org/W2083399493","https://openalex.org/W2083790580","https://openalex.org/W2084776559","https://openalex.org/W2087355617","https://openalex.org/W2088153090","https://openalex.org/W2092304285","https://openalex.org/W2095027102","https://openalex.org/W2095997878","https://openalex.org/W2096448596","https://openalex.org/W2100360129","https://openalex.org/W2101679774","https://openalex.org/W2104724413","https://openalex.org/W2105131190","https://openalex.org/W2111365428","https://openalex.org/W2115206864","https://openalex.org/W2122472501","https://openalex.org/W2122876469","https://openalex.org/W2123161963","https://openalex.org/W2129355183","https://openalex.org/W2130410599","https://openalex.org/W2130661964","https://openalex.org/W2132346004","https://openalex.org/W2134706686","https://openalex.org/W2137654289","https://openalex.org/W2138719823","https://openalex.org/W2142915976","https://openalex.org/W2148547093","https://openalex.org/W2150182456","https://openalex.org/W2152440317","https://openalex.org/W2152548322","https://openalex.org/W2152605304","https://openalex.org/W2154398657","https://openalex.org/W2156174439","https://openalex.org/W2157729110","https://openalex.org/W2158085108","https://openalex.org/W2163565535","https://openalex.org/W2165727837","https://openalex.org/W2167273447","https://openalex.org/W2167732573","https://openalex.org/W2170086069","https://openalex.org/W2187604395","https://openalex.org/W2307457245","https://openalex.org/W2313541759","https://openalex.org/W2314213298","https://openalex.org/W2314661484","https://openalex.org/W2330393631","https://openalex.org/W2332642667","https://openalex.org/W2334263927","https://openalex.org/W2338826424","https://openalex.org/W2397807342","https://openalex.org/W2405830933","https://openalex.org/W3141197395","https://openalex.org/W4237033680","https://openalex.org/W4249517110","https://openalex.org/W4253645796","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4247779503","https://openalex.org/W2177723349","https://openalex.org/W4401280665","https://openalex.org/W2539600999","https://openalex.org/W4280521881","https://openalex.org/W2465694343","https://openalex.org/W4406269469","https://openalex.org/W4366084907","https://openalex.org/W4387578128","https://openalex.org/W4211260912"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":21},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}