{"id":"https://openalex.org/W2225261071","doi":"https://doi.org/10.1093/ajcp/96.2.160","title":"Acute Basophilic Leukemia: A Clinical, Morphologic, and Cytogenetic Study of Eight Cases","display_name":"Acute Basophilic Leukemia: A Clinical, Morphologic, and Cytogenetic Study of Eight Cases","publication_year":1991,"publication_date":"1991-08-01","ids":{"openalex":"https://openalex.org/W2225261071","doi":"https://doi.org/10.1093/ajcp/96.2.160","mag":"2225261071","pmid":"https://pubmed.ncbi.nlm.nih.gov/1862771"},"language":"en","primary_location":{"id":"doi:10.1093/ajcp/96.2.160","doi":"https://doi.org/10.1093/ajcp/96.2.160","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/96.2.160","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050932576","display_name":"LoAnn C. Peterson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I2802288015","display_name":"Hennepin County Medical Center","ror":"https://ror.org/01k7a6660","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802288015"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Loann C. Peterson","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, Minneapolis, Minnesota","Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I2802288015"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084994730","display_name":"Janet L. Parkin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Janet L. Parkin","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110480067","display_name":"Diane C. Arthur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diane C. Arthur","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052071909","display_name":"Richard D. Brunning","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard D. Brunning","raw_affiliation_strings":["Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, Minnesota","institution_ids":["https://openalex.org/I130238516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050932576"],"corresponding_institution_ids":["https://openalex.org/I130238516","https://openalex.org/I2802288015"],"apc_list":{"value":4660,"currency":"USD","value_usd":4660},"apc_paid":null,"fwci":0.2538,"has_fulltext":false,"cited_by_count":70,"citation_normalized_percentile":{"value":0.56942042,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"96","issue":"2","first_page":"160","last_page":"170"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.029500000178813934,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-basophilic-leukemia","display_name":"acute basophilic leukemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ultrastructural-diagnosis","display_name":"ultrastructural diagnosis","score":0.5230000019073486},{"id":"https://openalex.org/keywords/basophil-granules","display_name":"basophil granules","score":0.9179999828338623},{"id":"https://openalex.org/keywords/philadelphia-chromosome","display_name":"Philadelphia chromosome","score":0.9010000228881836},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.875},{"id":"https://openalex.org/keywords/cytogenetics","display_name":"cytogenetics","score":0.6729999780654907},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.4819999933242798},{"id":"https://openalex.org/keywords/blast-morphology","display_name":"blast morphology","score":0.38600000739097595}],"concepts":[{"id":"https://openalex.org/C19210678","wikidata":"https://www.wikidata.org/wiki/Q672718","display_name":"Basophilic","level":2,"score":0.9485952258110046},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.6914114952087402},{"id":"https://openalex.org/C2777456892","wikidata":"https://www.wikidata.org/wiki/Q107988","display_name":"Basophil","level":4,"score":0.6886412501335144},{"id":"https://openalex.org/C87555872","wikidata":"https://www.wikidata.org/wiki/Q3141316","display_name":"Ultrastructure","level":2,"score":0.6198189854621887},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.5728569626808167},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.5384032726287842},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.537846028804779},{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.5316059589385986},{"id":"https://openalex.org/C2776863199","wikidata":"https://www.wikidata.org/wiki/Q976388","display_name":"Acute leukemia","level":3,"score":0.47524213790893555},{"id":"https://openalex.org/C53226629","wikidata":"https://www.wikidata.org/wiki/Q189967","display_name":"Karyotype","level":4,"score":0.4682009816169739},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3209765553474426},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2792968153953552},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.22924020886421204},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10769590735435486},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.06749629974365234},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003582","descriptor_name":"Cytogenetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004253","descriptor_name":"DNA Nucleotidylexotransferase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006651","descriptor_name":"Histocytochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010677","descriptor_name":"Philadelphia Chromosome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015471","descriptor_name":"Leukemia, Basophilic, Acute","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D015471","descriptor_name":"Leukemia, Basophilic, Acute","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015471","descriptor_name":"Leukemia, Basophilic, Acute","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/ajcp/96.2.160","doi":"https://doi.org/10.1093/ajcp/96.2.160","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/96.2.160","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},{"id":"pmid:1862771","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1862771","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of clinical pathology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2277001697","https://openalex.org/W2035795753","https://openalex.org/W2038980466","https://openalex.org/W1985208448","https://openalex.org/W2067844014","https://openalex.org/W1977619732","https://openalex.org/W2067273169","https://openalex.org/W2021737243","https://openalex.org/W1983548533","https://openalex.org/W2414788695"],"abstract_inverted_index":{"The":[0,24,121],"authors":[1,122],"describe":[2],"eight":[3,13,59],"cases":[4,25,60,109],"of":[5,11,31,38,74,99,158],"acute":[6,104,133,137],"basophilic":[7,15,134,138],"leukemia.":[8,106],"In":[9,69],"six":[10],"the":[12,29,39,108,144,149],"cases,":[14,71],"involvement":[16],"was":[17,79],"not":[18],"apparent":[19],"by":[20],"light":[21],"microscopic":[22],"examination.":[23],"were":[26,110],"identified":[27],"on":[28],"basis":[30],"ultrastructural":[32,72,125,150],"evidence":[33,73,85,153],"for":[34,86,154],"basophil/mast":[35],"cell":[36,76,91],"differentiation":[37,45,77],"blasts":[40,56,65],"with":[41,81,103,143],"little":[42],"or":[43],"no":[44],"into":[46],"other":[47],"lineages.":[48],"Ultrastructural":[49],"analysis":[50,126],"revealed":[51],"immature":[52],"basophil":[53,88],"granules":[54,63],"in":[55,57,64,66],"all":[58],"and":[61,89,147,160],"theta":[62],"four":[67],"cases.":[68],"three":[70],"mast":[75,90,161],"also":[78],"present,":[80],"rare":[82],"cells":[83],"showing":[84],"both":[87],"differentiation.":[92],"No":[93],"clinical":[94],"features":[95],"distinguished":[96],"this":[97],"group":[98],"patients":[100],"from":[101],"others":[102],"myeloid":[105],"Cytogenetically,":[107],"heterogeneous.":[111],"Three":[112],"had":[113,118],"a":[114,119,155],"Philadelphia":[115,145],"chromosome;":[116],"none":[117],"t(6;9).":[120],"conclude":[123],"that":[124,136,148],"usually":[127],"must":[128],"be":[129],"used":[130],"to":[131],"diagnose":[132],"leukemia,":[135],"leukemia":[139],"is":[140],"associated":[141],"frequently":[142],"chromosome,":[146],"findings":[151],"provide":[152],"common":[156],"origin":[157],"basophils":[159],"cells.":[162]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}