{"id":"https://openalex.org/W2224770524","doi":null,"title":"CB1 Receptor Antagonist AM-251: Effect on Spatial Memory in Male Mice","display_name":"CB1 Receptor Antagonist AM-251: Effect on Spatial Memory in Male Mice","publication_year":2009,"publication_date":"2009-10-13","ids":{"openalex":"https://openalex.org/W2224770524","mag":"2224770524"},"language":"en","primary_location":{"id":"pmh:oai:dspace.calstate.edu:10211.3/10211.4_83","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10211.3/10211.4_83","pdf_url":"http://hdl.handle.net/10211.3/10211.4_83","source":{"id":"https://openalex.org/S7407064448","display_name":"California State University ScholarWorks (system-wide DSpace)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10211.3/10211.4_83","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011556194","display_name":"Brannon M. Green","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Brannon Green","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5011556194"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.02370000071823597,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10918","display_name":"Memory Processes and Influences","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/am251","display_name":"AM251","score":0.9020000100135803},{"id":"https://openalex.org/keywords/cb1-receptor-antagonist","display_name":"CB1 receptor antagonist","score":0.8330000042915344},{"id":"https://openalex.org/keywords/endocannabinoid-system","display_name":"endocannabinoid system","score":0.9139999747276306},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.9890000224113464},{"id":"https://openalex.org/keywords/memory-retrieval","display_name":"memory retrieval","score":0.9039999842643738},{"id":"https://openalex.org/keywords/morris-water-maze","display_name":"Morris water maze","score":0.6850000023841858},{"id":"https://openalex.org/keywords/cannabinoid-receptor-antagonism","display_name":"cannabinoid receptor antagonism","score":0.6169999837875366},{"id":"https://openalex.org/keywords/c57bl-6-mice","display_name":"C57BL/6 mice","score":0.8220000267028809}],"concepts":[{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.8807027339935303},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.8154793977737427},{"id":"https://openalex.org/C148001335","wikidata":"https://www.wikidata.org/wiki/Q421237","display_name":"Cannabinoid receptor","level":4,"score":0.6578158140182495},{"id":"https://openalex.org/C12515866","wikidata":"https://www.wikidata.org/wiki/Q50628021","display_name":"Water maze","level":3,"score":0.5874520540237427},{"id":"https://openalex.org/C2780871563","wikidata":"https://www.wikidata.org/wiki/Q422936","display_name":"Cannabinoid","level":3,"score":0.5658290386199951},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5083627104759216},{"id":"https://openalex.org/C2778122271","wikidata":"https://www.wikidata.org/wiki/Q410943","display_name":"Receptor antagonist","level":4,"score":0.46146160364151},{"id":"https://openalex.org/C46721173","wikidata":"https://www.wikidata.org/wiki/Q368952","display_name":"Endocannabinoid system","level":3,"score":0.4455929100513458},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.33589863777160645},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2621113359928131},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22534021735191345},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.15374460816383362},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.12626996636390686}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:dspace.calstate.edu:10211.3/10211.4_83","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10211.3/10211.4_83","pdf_url":"http://hdl.handle.net/10211.3/10211.4_83","source":{"id":"https://openalex.org/S7407064448","display_name":"California State University ScholarWorks (system-wide DSpace)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:oai:scholarworks.calstate.edu:10211.4/83","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10211.4/83","pdf_url":null,"source":{"id":"https://openalex.org/S4306402638","display_name":"CSUN ScholarWorks (California State University, Northridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I157638225","host_organization_name":"California State University, Northridge","host_organization_lineage":["https://openalex.org/I157638225"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null},{"id":"mag:2224770524","doi":null,"is_oa":false,"landing_page_url":"http://scholarworks.calstate.edu/handle/10211.4/83","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:dspace.calstate.edu:10211.3/10211.4_83","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10211.3/10211.4_83","pdf_url":"http://hdl.handle.net/10211.3/10211.4_83","source":{"id":"https://openalex.org/S7407064448","display_name":"California State University ScholarWorks (system-wide DSpace)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2224770524.pdf","grobid_xml":"https://content.openalex.org/works/W2224770524.grobid-xml"},"referenced_works_count":73,"referenced_works":["https://openalex.org/W62415273","https://openalex.org/W157867011","https://openalex.org/W1488329806","https://openalex.org/W1597278618","https://openalex.org/W1654380405","https://openalex.org/W1836729582","https://openalex.org/W1844090762","https://openalex.org/W1965117109","https://openalex.org/W1965620797","https://openalex.org/W1968911801","https://openalex.org/W1970391423","https://openalex.org/W1986620071","https://openalex.org/W1989073099","https://openalex.org/W1989644542","https://openalex.org/W1991497324","https://openalex.org/W1991973951","https://openalex.org/W1992164240","https://openalex.org/W1993681287","https://openalex.org/W1995359090","https://openalex.org/W1996302313","https://openalex.org/W2000144084","https://openalex.org/W2009732294","https://openalex.org/W2011695609","https://openalex.org/W2015614945","https://openalex.org/W2017255572","https://openalex.org/W2018702809","https://openalex.org/W2025055783","https://openalex.org/W2027352187","https://openalex.org/W2029775732","https://openalex.org/W2031439839","https://openalex.org/W2035980199","https://openalex.org/W2038266242","https://openalex.org/W2046507387","https://openalex.org/W2047297178","https://openalex.org/W2050641367","https://openalex.org/W2051030173","https://openalex.org/W2052496571","https://openalex.org/W2058051322","https://openalex.org/W2058578514","https://openalex.org/W2059363316","https://openalex.org/W2059421922","https://openalex.org/W2062152100","https://openalex.org/W2062723619","https://openalex.org/W2065788111","https://openalex.org/W2067703623","https://openalex.org/W2069751705","https://openalex.org/W2071059133","https://openalex.org/W2072759829","https://openalex.org/W2076039092","https://openalex.org/W2080872002","https://openalex.org/W2081525577","https://openalex.org/W2085802434","https://openalex.org/W2086781281","https://openalex.org/W2088083175","https://openalex.org/W2089619028","https://openalex.org/W2092441620","https://openalex.org/W2095418258","https://openalex.org/W2100338555","https://openalex.org/W2103903337","https://openalex.org/W2112924959","https://openalex.org/W2118091961","https://openalex.org/W2123700490","https://openalex.org/W2124248227","https://openalex.org/W2127696179","https://openalex.org/W2133394764","https://openalex.org/W2134004988","https://openalex.org/W2149601015","https://openalex.org/W2160485854","https://openalex.org/W2169473035","https://openalex.org/W2171275714","https://openalex.org/W2434117662","https://openalex.org/W2766965424","https://openalex.org/W4322703223"],"related_works":["https://openalex.org/W2061061104","https://openalex.org/W2073473812","https://openalex.org/W1995612817","https://openalex.org/W2033377716","https://openalex.org/W1512723324","https://openalex.org/W1522398482","https://openalex.org/W7219507289","https://openalex.org/W1969858878","https://openalex.org/W2325550621","https://openalex.org/W2012675758"],"abstract_inverted_index":{"ABSTRACT":[0],"\\nCB1":[1],"RECEPTOR":[2],"ANTAGONIST":[3],"AM-251:":[4],"EFFECT":[5],"\\nON":[6],"SPATIAL":[7],"MEMORY":[8],"IN":[9],"MALE":[10],"MICE":[11],"\\nby":[12],"\\nBrannon":[13],"Micheal":[14],"Green":[15],"\\nMaster":[16],"of":[17,36,106],"Arts":[18],"in":[19,43],"Psychology":[20],"\\nPsychological":[21],"Science":[22],"Option":[23],"\\nCalifornia":[24],"State":[25],"University,":[26],"Chico":[27],"\\nSummer":[28],"2009":[29],"\\nThe":[30],"current":[31],"study":[32],"investigated":[33],"the":[34,37,81,90,98,114,122,133],"effect":[35],"endocannabinoid":[38],"system":[39],"on":[40,56,80,97,121,135,149],"\\nspatial":[41],"memory":[42,58,71,136],"mice.":[44],"We":[45],"hypothesized":[46],"that":[47],"a":[48,53,142],"cannabinoid":[49,139],"antagonist":[50,140],"would":[51],"have":[52],"\\nnegative":[54],"impact":[55,148],"spatial":[57,70],"retrieval":[59],"and":[60,85,94],"reacquisition":[61],"by":[62],"interrupting":[63],"normal":[64],"\\ncannabinoid":[65],"activity":[66],"associated":[67],"with":[68,88,113],"these":[69,107],"functions.":[72],"C57BL/6":[73],"male":[74],"mice":[75,108],"\\nwere":[76],"brought":[77],"to":[78,102,131],"criterion":[79],"Morris":[82,99,123],"Water":[83,100,124],"Maze":[84,101,125],"acutely":[86],"treated":[87,112],"either":[89],"\\nantagonist":[91],"or":[92,117],"vehicle,":[93],"were":[95,109,126],"retested":[96],"assess":[103],"retrieval.":[104],"\\nHalf":[105],"then":[110],"chronically":[111],"antagonist,":[115],"vehicle":[116],"saline.":[118],"\\nLatency":[119],"times":[120],"compared":[127],"over":[128],"10":[129],"days":[130],"evaluate":[132],"\\neffect":[134],"reacquisition.":[137],"The":[138],"had":[141],"small,":[143],"but":[144],"statistically":[145],"\\nsignificant,":[146],"negative":[147],"retrieval,":[150],"although":[151],"it":[152],"did":[153],"not":[154],"significantly":[155],"affect":[156],"\\nreacquisition.":[157],"\\nvi":[158]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
