{"id":"https://openalex.org/W2223927142","doi":null,"title":"Myelodysplastic syndromes (MDS) in Central Africans.","display_name":"Myelodysplastic syndromes (MDS) in Central Africans.","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2223927142","mag":"2223927142","pmid":"https://pubmed.ncbi.nlm.nih.gov/8165730"},"language":"en","primary_location":{"id":"pmid:8165730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8165730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical and geographical medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061236672","display_name":"Joshua M. Mukiibi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I153455119","display_name":"University of Zimbabwe","ror":"https://ror.org/04ze6rb18","country_code":"ZW","type":"education","lineage":["https://openalex.org/I153455119"]}],"countries":["ZW"],"is_corresponding":false,"raw_author_name":"J M Mukiibi","raw_affiliation_strings":["University of Zimbabwe, Medical School, Department of Haematology, Avondale, Harare"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Zimbabwe, Medical School, Department of Haematology, Avondale, Harare","institution_ids":["https://openalex.org/I153455119"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111811007","display_name":"B Paul","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Paul","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4769,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.65055872,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"46","issue":"1","first_page":"17","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9110999703407288,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.08529999852180481,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":1.0},{"id":"https://openalex.org/keywords/central-africa","display_name":"Central Africa","score":0.703000009059906},{"id":"https://openalex.org/keywords/refractory-anemia","display_name":"refractory anemia","score":0.8320000171661377},{"id":"https://openalex.org/keywords/ring-sideroblasts","display_name":"ring sideroblasts","score":0.8569999933242798},{"id":"https://openalex.org/keywords/chronic-myelomonocytic-leukemia","display_name":"chronic myelomonocytic leukemia","score":0.9290000200271606},{"id":"https://openalex.org/keywords/diagnostic-awareness","display_name":"diagnostic awareness","score":0.6850000023841858},{"id":"https://openalex.org/keywords/fab-classification","display_name":"FAB classification","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C2780817109","wikidata":"https://www.wikidata.org/wiki/Q954625","display_name":"Myelodysplastic syndromes","level":3,"score":0.8088822364807129},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6932935118675232},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5303987264633179},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.5032798647880554},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47903552651405334},{"id":"https://openalex.org/C551997983","wikidata":"https://www.wikidata.org/wiki/Q12167","display_name":"Malnutrition","level":2,"score":0.4763662815093994},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.47436317801475525},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4525716006755829},{"id":"https://openalex.org/C2777928532","wikidata":"https://www.wikidata.org/wiki/Q1088072","display_name":"Chronic myelomonocytic leukemia","level":4,"score":0.41406935453414917},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.13476228713989258},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1181725263595581},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10628366470336914},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005492","descriptor_name":"Folic Acid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014805","descriptor_name":"Vitamin B 12","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015030","descriptor_name":"Zimbabwe","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:8165730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8165730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tropical and geographical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:http://erepository.uonbi.ac.ke:11295/31072","doi":null,"is_oa":false,"landing_page_url":"http://www.ncbi.nlm.nih.gov/pubmed/8165730","pdf_url":null,"source":{"id":"https://openalex.org/S4306402107","display_name":"University of Nairobi Research Archive (University of Nairobi)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I12859529","host_organization_name":"University of Nairobi","host_organization_lineage":["https://openalex.org/I12859529"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"mag:2223927142","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8165730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2242681912","https://openalex.org/W2185881314","https://openalex.org/W255669957","https://openalex.org/W2412904967","https://openalex.org/W2192623785","https://openalex.org/W2472347952","https://openalex.org/W2412870611","https://openalex.org/W2028043063","https://openalex.org/W4417005220","https://openalex.org/W1992929601"],"abstract_inverted_index":{"Forty":[0],"two":[1],"patients":[2],"who":[3],"were":[4],"seen":[5],"and":[6,94,110,152],"satisfied":[7],"the":[8,22,102,106,133,140,161,171],"French-American-British":[9],"(FAB)":[10],"diagnostic":[11,165],"criteria":[12],"for":[13],"myelodysplastic":[14],"syndromes":[15],"(MDS)":[16],"over":[17],"a":[18,42,55,128,153],"6-year":[19],"period":[20],"at":[21],"University":[23],"of":[24,27,46,60,101,130,143,155,173],"Zimbabwe's":[25],"Department":[26],"Haematology,":[28],"Harare,":[29],"are":[30],"presented.":[31],"Their":[32],"overall":[33],"ages":[34],"ranged":[35],"from":[36],"29":[37],"to":[38,57,115,148,163],"75":[39],"years":[40],"with":[41,54,70,78,86],"mean":[43],"+/-":[44,48],"SD":[45],"57.8":[47],"11.2":[49],"years.":[50],"Males":[51],"outnumbered":[52],"females":[53],"male":[56],"female":[58],"ratio":[59],"1.2:1.":[61],"Refractory":[62],"anaemia":[63,69,77,85,131],"(RA)":[64],"occurred":[65],"in":[66,74,82,89,92,99,111,119,132,139],"33.3%;":[67],"refractory":[68,76,84],"ringed":[71],"sideroblasts":[72],"(RARS)":[73],"16.7%;":[75],"excess":[79,87],"blasts":[80,88],"(RAEB)":[81],"21.4%;":[83],"transformation":[90],"(RAEB-T)":[91],"16.7%":[93],"chronic":[95],"myelomonocytic":[96],"leukaemia":[97],"(CMML)":[98],"11.9%":[100],"patients.":[103],"In":[104],"90.5%":[105],"disease":[107],"was":[108],"primary":[109],"9.5%":[112],"prior":[113],"exposure":[114],"myelotoxic":[116],"agents":[117],"resulted":[118],"secondary":[120],"MDS.":[121],"The":[122],"study":[123],"reveals":[124],"that":[125],"MDS":[126],"as":[127],"cause":[129],"African":[134],"population":[135],"is":[136,159],"usually":[137],"hidden":[138],"big":[141],"number":[142],"well":[144],"known":[145],"anaemias":[146],"due":[147],"rampant":[149],"malaria,":[150],"malnutrition":[151],"host":[154],"nutritional":[156],"deficiencies.":[157],"There":[158],"therefore":[160],"need":[162],"increase":[164],"awareness":[166],"among":[167],"our":[168],"clinicians":[169],"about":[170],"existence":[172],"these":[174],"disorders.":[175]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}