{"id":"https://openalex.org/W2222005304","doi":null,"title":"Langzeitergebnisse nach semistereotaktischer, konventionell fraktionierter Strahlenbehandlung von arterioven\u00f6sen Malformationen des Gehirns","display_name":"Langzeitergebnisse nach semistereotaktischer, konventionell fraktionierter Strahlenbehandlung von arterioven\u00f6sen Malformationen des Gehirns","publication_year":2002,"publication_date":"2002-11-06","ids":{"openalex":"https://openalex.org/W2222005304","mag":"2222005304"},"language":"de","primary_location":{"id":"pmh:oai:duepublico.uni-duisburg-essen.de:10748","doi":null,"is_oa":true,"landing_page_url":"http://duepublico.uni-duisburg-essen.de/go/dissOnline/fb14/2002/wilms.marc","pdf_url":"http://duepublico.uni-duisburg-essen.de/servlets/DocumentServlet?id=10748","source":{"id":"https://openalex.org/S4306400212","display_name":"DuEPublico (University of Duisburg-Essen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I62318514","host_organization_name":"University of Duisburg-Essen","host_organization_lineage":["https://openalex.org/I62318514"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Wissenschaftliche Abschlussarbeiten \u00bb Dissertation"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://duepublico.uni-duisburg-essen.de/servlets/DocumentServlet?id=10748","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050604568","display_name":"Marc Ernst Wilms","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Marc Ernst Wilms","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050604568"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11402","display_name":"Vascular Malformations Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11402","display_name":"Vascular Malformations Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10980","display_name":"Vascular Malformations and Hemangiomas","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-arteriovenous-malformations","display_name":"cerebral arteriovenous malformations","score":0.9229999780654907},{"id":"https://openalex.org/keywords/stereotactic-radiotherapy","display_name":"stereotactic radiotherapy","score":0.753000020980835},{"id":"https://openalex.org/keywords/fractionated-radiotherapy","display_name":"fractionated radiotherapy","score":0.9049999713897705},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.8479999899864197},{"id":"https://openalex.org/keywords/avm-obliteration","display_name":"AVM obliteration","score":0.6919999718666077},{"id":"https://openalex.org/keywords/linear-accelerator-radiotherapy","display_name":"linear accelerator radiotherapy","score":0.5490000247955322},{"id":"https://openalex.org/keywords/radiation-induced-meningioma","display_name":"radiation-induced meningioma","score":0.4350000023841858},{"id":"https://openalex.org/keywords/radiation-induced-glioma","display_name":"radiation-induced glioma","score":0.4230000078678131},{"id":"https://openalex.org/keywords/radiation-induced-vasculopathy","display_name":"radiation-induced vasculopathy","score":0.3919999897480011},{"id":"https://openalex.org/keywords/radiation-induced-encephalopathy","display_name":"radiation-induced encephalopathy","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5952924489974976},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.452381432056427}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:duepublico.uni-duisburg-essen.de:10748","doi":null,"is_oa":true,"landing_page_url":"http://duepublico.uni-duisburg-essen.de/go/dissOnline/fb14/2002/wilms.marc","pdf_url":"http://duepublico.uni-duisburg-essen.de/servlets/DocumentServlet?id=10748","source":{"id":"https://openalex.org/S4306400212","display_name":"DuEPublico (University of Duisburg-Essen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I62318514","host_organization_name":"University of Duisburg-Essen","host_organization_lineage":["https://openalex.org/I62318514"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Wissenschaftliche Abschlussarbeiten \u00bb Dissertation"},{"id":"pmh:oai:duepublico2.uni-due.de:duepublico_mods_00010748","doi":null,"is_oa":true,"landing_page_url":"https://nbn-resolving.org/urn:nbn:de:hbz:465-miless-010748-5","pdf_url":"https://duepublico2.uni-due.de/receive/duepublico_mods_00010748","source":{"id":"https://openalex.org/S4306400212","display_name":"DuEPublico (University of Duisburg-Essen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I62318514","host_organization_name":"University of Duisburg-Essen","host_organization_lineage":["https://openalex.org/I62318514"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dissertation"},{"id":"pmh:oai:bibliographie.ub.uni-due.de:ubo_mods_00000212","doi":null,"is_oa":false,"landing_page_url":"https://primo.uni-due.de/discovery/search?tab=Everything&search_scope=MyInst_and_CI_custom&vid=49HBZ_UDE:UDE&lang=de&offset=0&query=holding_call_number,exact,%22ZZX637823%22","pdf_url":null,"source":{"id":"https://openalex.org/S7407055102","display_name":"Universit\u00e4tsbibliographie, Universit\u00e4t Duisburg-Essen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dissertation"},{"id":"mag:2222005304","doi":null,"is_oa":false,"landing_page_url":"https://duepublico2.uni-due.de/receive/duepublico_mods_00010748","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:duepublico.uni-duisburg-essen.de:10748","doi":null,"is_oa":true,"landing_page_url":"http://duepublico.uni-duisburg-essen.de/go/dissOnline/fb14/2002/wilms.marc","pdf_url":"http://duepublico.uni-duisburg-essen.de/servlets/DocumentServlet?id=10748","source":{"id":"https://openalex.org/S4306400212","display_name":"DuEPublico (University of Duisburg-Essen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I62318514","host_organization_name":"University of Duisburg-Essen","host_organization_lineage":["https://openalex.org/I62318514"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Wissenschaftliche Abschlussarbeiten \u00bb Dissertation"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2222005304.pdf","grobid_xml":"https://content.openalex.org/works/W2222005304.grobid-xml"},"referenced_works_count":105,"referenced_works":["https://openalex.org/W13424725","https://openalex.org/W25179832","https://openalex.org/W72663156","https://openalex.org/W76452102","https://openalex.org/W136533565","https://openalex.org/W139724943","https://openalex.org/W152319095","https://openalex.org/W174751717","https://openalex.org/W188734112","https://openalex.org/W1504746250","https://openalex.org/W1515334663","https://openalex.org/W1545136637","https://openalex.org/W1775639312","https://openalex.org/W1830762985","https://openalex.org/W1918751823","https://openalex.org/W1965061510","https://openalex.org/W1967796171","https://openalex.org/W1970407051","https://openalex.org/W1971627071","https://openalex.org/W1972840914","https://openalex.org/W1973470461","https://openalex.org/W1973705009","https://openalex.org/W1974117670","https://openalex.org/W1974148850","https://openalex.org/W1974569268","https://openalex.org/W1979036526","https://openalex.org/W1979804903","https://openalex.org/W1979983008","https://openalex.org/W1985651239","https://openalex.org/W1986616384","https://openalex.org/W1995624150","https://openalex.org/W1997247219","https://openalex.org/W1998873528","https://openalex.org/W1999474289","https://openalex.org/W2000402877","https://openalex.org/W2003311492","https://openalex.org/W2009279657","https://openalex.org/W2010254668","https://openalex.org/W2011262239","https://openalex.org/W2014083087","https://openalex.org/W2014208541","https://openalex.org/W2017283742","https://openalex.org/W2018620520","https://openalex.org/W2027739675","https://openalex.org/W2028030167","https://openalex.org/W2030610529","https://openalex.org/W2034221584","https://openalex.org/W2035109934","https://openalex.org/W2037803738","https://openalex.org/W2038008306","https://openalex.org/W2038802495","https://openalex.org/W2041744438","https://openalex.org/W2044334709","https://openalex.org/W2045492424","https://openalex.org/W2048020454","https://openalex.org/W2050529289","https://openalex.org/W2051433507","https://openalex.org/W2054990897","https://openalex.org/W2060015278","https://openalex.org/W2060665388","https://openalex.org/W2061894482","https://openalex.org/W2063319269","https://openalex.org/W2065568800","https://openalex.org/W2067129671","https://openalex.org/W2072723019","https://openalex.org/W2073005838","https://openalex.org/W2076043896","https://openalex.org/W2085363287","https://openalex.org/W2100788029","https://openalex.org/W2102766489","https://openalex.org/W2112276453","https://openalex.org/W2112531069","https://openalex.org/W2118380723","https://openalex.org/W2126321126","https://openalex.org/W2128994495","https://openalex.org/W2141001988","https://openalex.org/W2143669951","https://openalex.org/W2154902592","https://openalex.org/W2154970859","https://openalex.org/W2157863903","https://openalex.org/W2161284024","https://openalex.org/W2169972640","https://openalex.org/W2172326499","https://openalex.org/W2183483051","https://openalex.org/W2279957693","https://openalex.org/W2298740550","https://openalex.org/W2316750950","https://openalex.org/W2324079519","https://openalex.org/W2331414666","https://openalex.org/W2343789403","https://openalex.org/W2346447441","https://openalex.org/W2395166068","https://openalex.org/W2401660047","https://openalex.org/W2404704158","https://openalex.org/W2406589577","https://openalex.org/W2437760834","https://openalex.org/W2462830546","https://openalex.org/W2501511914","https://openalex.org/W2506104372","https://openalex.org/W2754592546","https://openalex.org/W2887705377","https://openalex.org/W3026529836","https://openalex.org/W3122314703","https://openalex.org/W4230762009","https://openalex.org/W4233290071"],"related_works":["https://openalex.org/W6983426205","https://openalex.org/W7025173009","https://openalex.org/W2975009144","https://openalex.org/W2405239844","https://openalex.org/W242623382","https://openalex.org/W4290128681","https://openalex.org/W7057916232","https://openalex.org/W2900951726","https://openalex.org/W6999459443","https://openalex.org/W4245704416"],"abstract_inverted_index":{"In":[0,183,218,246],"den":[1,15,184,272,291],"Jahren":[2],"1982":[3],"bis":[4,69,101],"1993":[5],"wurden":[6,158,203],"insgesamt":[7],"92":[8],"Patienten":[9,113,228,236],"(58":[10],"M\u00e4nner,":[11],"34":[12],"Frauen)":[13],"in":[14,27,95,121,123,130,151,171,206,290,293,366],"St\u00e4dtischen":[16],"Kliniken":[17],"Duisburg":[18],"wegen":[19],"einer":[20,25,103,124,275,309],"Arterioven\u00f6sen":[21],"Malformation":[22],"des":[23,197,200,259,307],"Gehirns":[24],"Strahlenbehandlung":[26,86,316],"fraktionierter":[28],"Technik":[29],"unterzogen.":[30],"Hierbei":[31,193],"handelte":[32],"es":[33],"sich":[34,188,254,303],"ausnahmslos":[35],"um":[36,40],"inoperable":[37],"F\u00e4lle":[38,64,174],"oder":[39],"Patienten,":[41],"die":[42,189,195,261,313,356],"eine":[43,176,255,295],"Operation":[44],"ablehnten.":[45],"Dementsprechend":[46],"waren":[47,241],"h\u00f6hergradige":[48],"Angiome":[49,168,210,365],"\u00fcberrepr\u00e4sentiert":[50],"(Spetzler-Grade:":[51],"I\u00b0:":[52],"3,3%,":[53],"II\u00b0:":[54],"19,6%,":[55],"III\u00b0:":[56],"32,6%,":[57],"IV\u00b0:":[58],"22,8%,":[59],"V\u00b0:21,7%).":[60],"Bei":[61],"32,6%":[62],"der":[63,66,92,167,173,179,207,209,221,227,232,247,249,283,298,325,335,339,367],"betrug":[65],"maximale":[67],"Durchmesser":[68,213],"drei":[70,75,215,280],"Zentimeter,":[71],"bei":[72,80,140,225,271],"31,5%":[73],"zwischen":[74],"und":[76,79,148,161,338,358],"sechs":[77,83],"Zentimeter":[78],"35,9%":[81],"\u00fcber":[82,361],"Zentimeter.":[84],"Die":[85,345],"wurde":[87,224],"vorgenommen":[88],"an":[89],"einem":[90],"Linearbeschleuniger":[91],"Grenzenergie":[93],"10MeV":[94],"Einzelfraktionen":[96,131,141],"von":[97,105,112,132,142,277],"2Gy":[98],"f\u00fcnfmal":[99],"w\u00f6chentlich":[100,135],"zu":[102],"Gesamtdosis":[104,119,128,138,149],"50Gy":[106],"(65":[107],"Patienten).":[108],"Eine":[109],"kleine":[110],"Anzahl":[111],"erhielt":[114],"auch":[115],"ein":[116,229,304],"alternatives":[117],"Konzept:":[118],"20Gy":[120],"4x5Gy":[122],"Woche":[125,145,154],"(23":[126],"Patienten),":[127,137],"48Gy":[129,139],"4Gy":[133],"2x":[134],"(2":[136],"4x2Gy":[143],"pro":[144,153],"(1":[146,155],"Patient)":[147],"51Gy":[150],"3x3Gy":[152],"Patient).":[156],"Kontrolluntersuchungen":[157],"angiographisch,":[159],"computertomographisch":[160],"kernspintomographisch":[162],"vorgenommen.":[163],"Insgesamt":[164],"blieben":[165],"70%":[166],"unver\u00e4ndert.":[169],"Nur":[170,235],"11,3%":[172],"konnte":[175],"vollst\u00e4ndige":[177,296],"Obliteration":[178,297],"AVM":[180,223,251],"nachgewiesen":[181],"werden.":[182,344],"restlichen":[185],"18,7%":[186],"stellte":[187],"Gef\u00e4\u00dfmi\u00dfbildung":[190],"verkleinert":[191],"dar.":[192],"entsprachen":[194],"Resultate":[196],"50Gy-Konzepts":[198],"denen":[199,294],"20Gy-Konzepts.":[201],"Totalobliterationen":[202],"fast":[204],"ausschlie\u00dflich":[205],"Untergruppe":[208,248],"beobachtet,":[211],"deren":[212],"unter":[214],"Zentimetern":[216,281],"betrug.":[217],"dieser":[219],"Gruppe":[220],"kleinen":[222,250],"29,2%":[226],"vollst\u00e4ndiger":[230],"Verschlu\u00df":[231],"L\u00e4sion":[233,299],"festgestellt.":[234],"mit":[237,274],"vollst\u00e4ndig":[238],"obliterierten":[239],"L\u00e4sionen":[240],"vor":[242],"weiteren":[243],"Angiomblutungen":[244],"gefeit.":[245],"(<3cm)":[252],"zeigte":[253,302],"Tendenz":[256],"zur":[257],"Abnahme":[258],"Blutungsrisikos,":[260],"jedoch":[262,355],"statistisch":[263,286],"nicht":[264],"signifikant":[265,287],"war.":[266],"Demgegen\u00fcber":[267],"stieg":[268],"das":[269],"Blutungsrisiko":[270],"Angiomen":[273],"Gr\u00f6\u00dfe":[276],"mehr":[278],"als":[279],"nach":[282],"Radiatio":[284],"noch":[285],"an.":[288],"Auch":[289,330],"F\u00e4llen,":[292],"ausgeblieben":[300],"war,":[301],"signifikanter":[305],"Anstieg":[306],"Risikos":[308],"Angiomblutung.":[310],"Heutzutage":[311],"ist":[312,354],"konventionell":[314,362],"fraktionierte":[315],"zerebraler":[317],"Arterioven\u00f6ser":[318],"Malformationen":[319],"aufgrund":[320],"ihrer":[321],"schlechten":[322],"Ergebnisse":[323],"zugunsten":[324],"stereotaktischen":[326],"Einzeittherapie":[327],"verlassen":[328],"worden.":[329],"konnten":[331],"auf":[332],"dem":[333],"Gebiet":[334],"neurochirurgischen":[336],"Mikrochirurgie":[337],"Embolisationstechnik":[340],"entscheidende":[341],"Fortschritte":[342],"errungen":[343],"vorliegende":[346],"Studie":[347,360],"hat":[348],"insofern":[349],"eher":[350],"historischen":[351],"Wert.":[352],"Sie":[353],"gr\u00f6\u00dfte":[357],"einheitlichste":[359],"fraktioniert":[363],"bestrahlte":[364],"verf\u00fcgbaren":[368],"Literatur.":[369]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}