{"id":"https://openalex.org/W2214835533","doi":"https://doi.org/10.1152/ajpregu.1983.244.1.r93","title":"Sex differences in the circadian control of hamster wheel-running activity","display_name":"Sex differences in the circadian control of hamster wheel-running activity","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W2214835533","doi":"https://doi.org/10.1152/ajpregu.1983.244.1.r93","mag":"2214835533","pmid":"https://pubmed.ncbi.nlm.nih.gov/6849422"},"language":"en","primary_location":{"id":"doi:10.1152/ajpregu.1983.244.1.r93","doi":"https://doi.org/10.1152/ajpregu.1983.244.1.r93","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.1983.244.1.r93","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018952013","display_name":"Fred C. Davis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. C. Davis","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051099113","display_name":"Janet M. Darrow","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. M. Darrow","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111840073","display_name":"Michael Menaker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Menaker","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2482,"has_fulltext":false,"cited_by_count":99,"citation_normalized_percentile":{"value":0.76377171,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"244","issue":"1","first_page":"R93","last_page":"R105"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circadian-pacemaker","display_name":"circadian pacemaker","score":0.8500000238418579},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7760000228881836},{"id":"https://openalex.org/keywords/wheel-running","display_name":"wheel running","score":0.7950000166893005},{"id":"https://openalex.org/keywords/hamster","display_name":"hamster","score":0.800000011920929},{"id":"https://openalex.org/keywords/light-induced-phase-shift","display_name":"light-induced phase shift","score":0.7879999876022339},{"id":"https://openalex.org/keywords/free-running-period","display_name":"free-running period","score":0.8180000185966492},{"id":"https://openalex.org/keywords/castration","display_name":"castration","score":0.9610000252723694},{"id":"https://openalex.org/keywords/sex-steroids","display_name":"sex steroids","score":0.9520000219345093},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.6660000085830688},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C139992725","wikidata":"https://www.wikidata.org/wiki/Q5380656","display_name":"Entrainment (biomusicology)","level":3,"score":0.8805940747261047},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.6583949327468872},{"id":"https://openalex.org/C2910755853","wikidata":"https://www.wikidata.org/wiki/Q17130203","display_name":"Light Cycle","level":3,"score":0.6554544568061829},{"id":"https://openalex.org/C2779256933","wikidata":"https://www.wikidata.org/wiki/Q58929","display_name":"Castration","level":3,"score":0.5742793679237366},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.5673090815544128},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5558685064315796},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5336487889289856},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.5270669460296631},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4931737780570984},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21618551015853882},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.15153756737709045}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002369","descriptor_name":"Castration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002940","descriptor_name":"Circadian Rhythm","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008647","descriptor_name":"Mesocricetus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D010507","descriptor_name":"Periodicity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpregu.1983.244.1.r93","doi":"https://doi.org/10.1152/ajpregu.1983.244.1.r93","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.1983.244.1.r93","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},{"id":"pmid:6849422","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6849422","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4415353591","https://openalex.org/W3006470227","https://openalex.org/W1980983198","https://openalex.org/W1976602242","https://openalex.org/W2199744762","https://openalex.org/W2075422398","https://openalex.org/W2060196233","https://openalex.org/W2024773508","https://openalex.org/W1987190901","https://openalex.org/W1995997919"],"abstract_inverted_index":{"The":[0],"circadian":[1],"pacemaker":[2,26,228],"that":[3,117,205],"underlies":[4],"the":[5,21,25,33,69,81,97,108,118,132,189,199,206,221,227],"wheel-running":[6],"activity":[7,36,173,210,225],"of":[8,35,47,53,72,83,106,131,136,150,191,198,223],"hamsters":[9],"was":[10],"studied":[11],"in":[12,20,32,68,80,90,100,111,188,196,209,220,229],"males":[13,55,151,175,231],"and":[14,31,176,195,232],"females.":[15,65,179,233],"Sex":[16],"differences":[17],"were":[18,167],"found":[19,168],"mechanism":[22],"by":[23,216],"which":[24],"entrains":[27],"to":[28,40,60,76,96,145,153,159,169,226],"light-dark":[29,42,162],"cycles":[30],"timing":[34],"onset.":[37],"When":[38],"exposed":[39],"a":[41,45,57,77,160,185,217],"cycle":[43,163],"with":[44,184],"period":[46,92],"24.75":[48],"h":[49,52],"(with":[50],"1":[51],"light/cycle),":[54],"show":[56],"greater":[58],"ability":[59,144],"maintain":[61],"entrainment":[62,73,112,155,158,197],"than":[63],"do":[64],"This":[66,180],"difference":[67,79,89,99,110,119,181,187,208,219],"upper":[70],"limit":[71],"appears":[74],"due":[75],"sex":[78,98,109,186,207,218],"magnitude":[82,190],"light-induced":[84,192],"phase":[85,193],"shifts.":[86],"A":[87],"small":[88],"free-running":[91],"may":[93],"also":[94,213],"contribute":[95],"entrainment.":[101],"Two":[102],"weeks":[103],"after":[104],"castration":[105,135,149],"adults,":[107],"is":[113,182,203],"not":[114,121],"affected,":[115],"indicating":[116],"does":[120],"depend":[122],"on":[123,128],"circulating":[124],"gonadal":[125],"steroids":[126],"or":[127],"estrous":[129],"cyclicity":[130],"female.":[133],"However,":[134,201],"females":[137,166],"at":[138],"an":[139],"early":[140],"age":[141],"increases":[142],"their":[143,171],"entrain,":[146],"whereas":[147],"long-term":[148],"seems":[152],"reduce":[154],"ability.":[156],"During":[157],"24-h":[161],"(LD":[164],"14:10),":[165],"begin":[170],"daily":[172],"before":[174,177],"castrated":[178],"consistent":[183],"shifts":[194],"pacemaker.":[200],"evidence":[202],"given":[204],"onset":[211],"might":[212],"be":[214],"caused":[215],"relationship":[222],"locomotor":[224],"intact":[230]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}